-
1
-
-
17244373451
-
Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort
-
Alarcon-Segovia D, Alarcon-Riquelme ME, Cardiel MH, Caeiro F, Massardo L, Villa AR, et al. Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. Arthritis Rheum 2005;52:1138-47.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1138-1147
-
-
Alarcon-Segovia, D.1
Alarcon-Riquelme, M.E.2
Cardiel, M.H.3
Caeiro, F.4
Massardo, L.5
Villa, A.R.6
-
2
-
-
0035069106
-
A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases
-
Jawaheer D, Seldin MF, Amos Cl, Chen WV, Shlgeta R, Monteiro J, et al. A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Hum Genet 2001;68:927-36.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 927-936
-
-
Jawaheer, D.1
Seldin, M.F.2
Amos, C.3
Chen, W.V.4
Shlgeta, R.5
Monteiro, J.6
-
3
-
-
0023500817
-
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
-
Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987;30:1205-13.
-
(1987)
Arthritis Rheum
, vol.30
, pp. 1205-1213
-
-
Gregersen, P.K.1
Silver, J.2
Winchester, R.J.3
-
4
-
-
9144273357
-
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences
-
Kochi Y, Yamada R, Kobayashi K, Takahashi A, Suzuki A, Seklne A, et al. Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences. Arthritis Rheum 2004;50:63-71.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 63-71
-
-
Kochi, Y.1
Yamada, R.2
Kobayashi, K.3
Takahashi, A.4
Suzuki, A.5
Seklne, A.6
-
6
-
-
18544367934
-
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus
-
Graham RR, Ortmann WA, Langefeld CD, Jawaheer D, Selby SA, Rodine PR, et al. Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet 2002;71:543-53.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 543-553
-
-
Graham, R.R.1
Ortmann, W.A.2
Langefeld, C.D.3
Jawaheer, D.4
Selby, S.A.5
Rodine, P.R.6
-
7
-
-
28144441356
-
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: Association of susceptibility with PTPN22, CTLA4, and PADI4
-
Plenge RM, Padyukov L, Remmers EF, Purcell S, Lee AT, Karlson EW, et al. Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet 2005;77:1044-60.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 1044-1060
-
-
Plenge, R.M.1
Padyukov, L.2
Remmers, E.F.3
Purcell, S.4
Lee, A.T.5
Karlson, E.W.6
-
8
-
-
33845578510
-
The PTPN22 C1858T functional polymorphism and autoimmune diseases - a meta-analysis
-
Lee YH, Rho YH, Choi SJ, Ji JD, Song GG, Nath SK, et al. The PTPN22 C1858T functional polymorphism and autoimmune diseases - a meta-analysis. Rheumatology (Oxford) 2007;46:49-56.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 49-56
-
-
Lee, Y.H.1
Rho, Y.H.2
Choi, S.J.3
Ji, J.D.4
Song, G.G.5
Nath, S.K.6
-
9
-
-
34548427925
-
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
-
Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, Behrens TW, et al. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med 2007;357:977-86.
-
(2007)
N Engl J Med
, vol.357
, pp. 977-986
-
-
Remmers, E.F.1
Plenge, R.M.2
Lee, A.T.3
Graham, R.R.4
Hom, G.5
Behrens, T.W.6
-
10
-
-
13844292408
-
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
-
Sigurdsson S, Nordmark G, Goring HH, Lindroos K, Wiman AC, Sturfelt G, et al. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 2005;76:528-37.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 528-537
-
-
Sigurdsson, S.1
Nordmark, G.2
Goring, H.H.3
Lindroos, K.4
Wiman, A.C.5
Sturfelt, G.6
-
11
-
-
33646368404
-
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
-
Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, et al. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 2006;38:550-5.
-
(2006)
Nat Genet
, vol.38
, pp. 550-555
-
-
Graham, R.R.1
Kozyrev, S.V.2
Baechler, E.C.3
Reddy, M.V.4
Plenge, R.M.5
Bauer, J.W.6
-
12
-
-
34247628971
-
Replication of genetic effects of interferon regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population
-
Shin HD, Sung YK, Choi CB, Lee SO, Lee HW, Bae SC. Replication of genetic effects of interferon regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population. Arthritis Res Ther 2007;9:R32.
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Shin, H.D.1
Sung, Y.K.2
Choi, C.B.3
Lee, S.O.4
Lee, H.W.5
Bae, S.C.6
-
13
-
-
34247254495
-
Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus
-
Kozyrev SV, Lewen S, Reddy PM, Pons-Estel B, Witte T, Junker P, et al. Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus. Arthritis Rheum 2007;56:1234-41.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1234-1241
-
-
Kozyrev, S.V.1
Lewen, S.2
Reddy, P.M.3
Pons-Estel, B.4
Witte, T.5
Junker, P.6
-
14
-
-
34247162727
-
Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE)
-
Demirci FY, Manzi S, Ramsey-Goldman R, Minster RL, Kenney M, Shaw PS, et al. Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE). Ann Hum Genet 2007;71:308-11.
-
(2007)
Ann Hum Genet
, vol.71
, pp. 308-311
-
-
Demirci, F.Y.1
Manzi, S.2
Ramsey-Goldman, R.3
Minster, R.L.4
Kenney, M.5
Shaw, P.S.6
-
15
-
-
34249860408
-
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
-
Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, et al. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci USA 2007;104:6758-63.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6758-6763
-
-
Graham, R.R.1
Kyogoku, C.2
Sigurdsson, S.3
Vlasova, I.A.4
Davies, L.R.5
Baechler, E.C.6
-
16
-
-
34547541897
-
Opposed independent effects and epistasis in the complex association of IRF5 to SLE
-
Ferreiro-Neira I, Calaza M, Alonso-Perez E, Marchini M, Scorza R, Sebastiani GD, et al. Opposed independent effects and epistasis in the complex association of IRF5 to SLE. Genes Immun 2007;8:429-38.
-
(2007)
Genes Immun
, vol.8
, pp. 429-438
-
-
Ferreiro-Neira, I.1
Calaza, M.2
Alonso-Perez, E.3
Marchini, M.4
Scorza, R.5
Sebastiani, G.D.6
-
17
-
-
34247125683
-
Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation
-
Cunninghame Graham DS, Manku H, Wagner S, Reid J, Timms K, Gutin A, et al. Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation. Hum Mol Genet 2007;16:579-91.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 579-591
-
-
Cunninghame Graham, D.S.1
Manku, H.2
Wagner, S.3
Reid, J.4
Timms, K.5
Gutin, A.6
-
18
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
Morley M, Molony CM, Weber TM, Devlin JL, Ewens KG, Splelman RS, et al. Genetic analysis of genome-wide variation in human gene expression. Nature 2004;430:743-7.
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
Molony, C.M.2
Weber, T.M.3
Devlin, J.L.4
Ewens, K.G.5
Splelman, R.S.6
-
19
-
-
27644482314
-
Mapping determinants of human gene expression by regional and genome-wide association
-
Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT. Mapping determinants of human gene expression by regional and genome-wide association. Nature 2005;437:1365-9.
-
(2005)
Nature
, vol.437
, pp. 1365-1369
-
-
Cheung, V.G.1
Spielman, R.S.2
Ewens, K.G.3
Weber, T.M.4
Morley, M.5
Burdick, J.T.6
-
20
-
-
40649121122
-
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus
-
Sigurdsson S, Goring HH, Kristjansdottir G, Milani L, Nordmark G, Sandling J, et al. Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus. Hum Mol Genet 2008;17:872-81.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 872-881
-
-
Sigurdsson, S.1
Goring, H.H.2
Kristjansdottir, G.3
Milani, L.4
Nordmark, G.5
Sandling, J.6
-
21
-
-
36249002287
-
An insertion-deletion polymorphism in the interferon regulatory factor 5 (IRF5) gene confers risk of inflammatory bowel diseases
-
Dideberg V, Kristjansdottir G, Milani L, Libioulle C, Sigurdsson S, Louis E, et al. An insertion-deletion polymorphism in the interferon regulatory factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet 2007;16:3008-16.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 3008-3016
-
-
Dideberg, V.1
Kristjansdottir, G.2
Milani, L.3
Libioulle, C.4
Sigurdsson, S.5
Louis, E.6
-
22
-
-
33845623329
-
Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis
-
Rueda B, Reddy MV, Gonzalez-Gay MA, Balsa A, Pascual-Salcedo D, Petersson IF, et al. Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis. Arthritis Rheum 2006;54:3815-9.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3815-3819
-
-
Rueda, B.1
Reddy, M.V.2
Gonzalez-Gay, M.A.3
Balsa, A.4
Pascual-Salcedo, D.5
Petersson, I.F.6
-
23
-
-
34249815199
-
IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis
-
Gamier S, Dieude P, Michou L, Barbet S, Tan A, Lasbleiz S, et al. IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis. Ann Rheum Dis 2007;66:828-31.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 828-831
-
-
Gamier, S.1
Dieude, P.2
Michou, L.3
Barbet, S.4
Tan, A.5
Lasbleiz, S.6
-
24
-
-
34547492359
-
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis
-
Sigurdsson S, Padyukov L, Kurreeman FA, Liljedahl U, Wiman AC, Alfredsson L, et al. Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis. Arthritis Rheum 2007;56:2202-10.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2202-2210
-
-
Sigurdsson, S.1
Padyukov, L.2
Kurreeman, F.A.3
Liljedahl, U.4
Wiman, A.C.5
Alfredsson, L.6
-
25
-
-
0042667153
-
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
-
Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet 2003;34:395-402.
-
(2003)
Nat Genet
, vol.34
, pp. 395-402
-
-
Suzuki, A.1
Yamada, R.2
Chang, X.3
Tokuhiro, S.4
Sawada, T.5
Suzuki, M.6
-
26
-
-
0344364566
-
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
-
Tokuhiro S, Yamada R, Chang X, Suzuki A, Kochi Y, Sawada T, et al. An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet 2003;35:341-8.
-
(2003)
Nat Genet
, vol.35
, pp. 341-348
-
-
Tokuhiro, S.1
Yamada, R.2
Chang, X.3
Suzuki, A.4
Kochi, Y.5
Sawada, T.6
-
27
-
-
20944434679
-
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
-
Kochi Y, Yamada R, Suzuki A, Harley JB, Shirasawa S, Sawada T, et al. A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet 2005;37:478-85.
-
(2005)
Nat Genet
, vol.37
, pp. 478-485
-
-
Kochi, Y.1
Yamada, R.2
Suzuki, A.3
Harley, J.B.4
Shirasawa, S.5
Sawada, T.6
-
28
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
McShane, D.J.4
Fries, J.F.5
Cooper, N.S.6
-
29
-
-
20444368020
-
-
Mancl ME, Hu G, Sangster-Guity N, Olshalsky SL, Hoops K, Fitzgerald-Bocarsly P, et al. Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function. J Biol Chem 2005;280:21078-90.
-
Mancl ME, Hu G, Sangster-Guity N, Olshalsky SL, Hoops K, Fitzgerald-Bocarsly P, et al. Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function. J Biol Chem 2005;280:21078-90.
-
-
-
-
30
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 2005;434:243-9.
-
(2005)
Nature
, vol.434
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
Mizutani, T.6
-
31
-
-
3142769762
-
Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis
-
van Gaalen FA, van Aken J, Huizinga TW, Schreuder GM, Breedveld FC, Zanelli E, et al. Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis. Arthritis Rheum 2004;50:2113-21.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2113-2121
-
-
van Gaalen, F.A.1
van Aken, J.2
Huizinga, T.W.3
Schreuder, G.M.4
Breedveld, F.C.5
Zanelli, E.6
-
32
-
-
27744550413
-
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins
-
Huizinga TW, Amos Cl, van der Helm-van Mil AH, Chen W, van Gaalen FA, Jawaheer D, et al. Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis Rheum 2005;52:3433-8.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3433-3438
-
-
Huizinga, T.W.1
Amos, C.2
van der Helm-van Mil, A.H.3
Chen, W.4
van Gaalen, F.A.5
Jawaheer, D.6
-
33
-
-
29144460980
-
Regulation of anticyclic citrullinated peptide antibodies in rheumatoid arthritis: Contrasting effects of HLA-DR3 and the shared epitope alleles
-
Irigoyen P, Lee AT, Wener MH, Li W, Kern M, Batliwalla F, et al. Regulation of anticyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles. Arthritis Rheum 2005;52:3813-8.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3813-3818
-
-
Irigoyen, P.1
Lee, A.T.2
Wener, M.H.3
Li, W.4
Kern, M.5
Batliwalla, F.6
-
34
-
-
26844438822
-
Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis
-
Verpoort KN, van Gaalen FA, van der Helm-van Mil AH, Schreuder GM, Breedveld FC, Huizinga TW, et al. Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis. Arthritis Rheum 2005;52:3058-62.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3058-3062
-
-
Verpoort, K.N.1
van Gaalen, F.A.2
van der Helm-van Mil, A.H.3
Schreuder, G.M.4
Breedveld, F.C.5
Huizinga, T.W.6
-
35
-
-
18544362452
-
Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis
-
Jawaheer D, Li W, Graham RR, Chen W, Damle A, Xiao X, et al. Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. Am J Hum Genet 2002;71:585-94.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 585-594
-
-
Jawaheer, D.1
Li, W.2
Graham, R.R.3
Chen, W.4
Damle, A.5
Xiao, X.6
-
36
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003;423:356-61.
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
-
37
-
-
0018830639
-
Immunisation against heterologous type II collagen induces arthritis in mice
-
Courtenay JS, Dallman MJ, Dayan AD, Martin A, Mosedale B. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 1980;283:666-8.
-
(1980)
Nature
, vol.283
, pp. 666-668
-
-
Courtenay, J.S.1
Dallman, M.J.2
Dayan, A.D.3
Martin, A.4
Mosedale, B.5
-
38
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
-
Keffer J, Probert L, Cazlaris H, Georgopoulos S, Kaslaris E, Kioussls D, et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J 1991;10:4025-31.
-
(1991)
EMBO J
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
Probert, L.2
Cazlaris, H.3
Georgopoulos, S.4
Kaslaris, E.5
Kioussls, D.6
-
39
-
-
19244364722
-
Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis
-
Mulcahy B, Waldron-Lynch F, McDermott MF, Adams C, Amos Cl, Zhu DK, et al. Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis. Am J Hum Genet 1996;59:676-83.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 676-683
-
-
Mulcahy, B.1
Waldron-Lynch, F.2
McDermott, M.F.3
Adams, C.4
Amos, C.5
Zhu, D.K.6
|