Progressive nuclear translocation of somatostatin analogs

Journal of Nuclear Medicine

Volumn 41, Issue 7, 2000, Pages 1256-1263

  Hornick, Conrad A ^b   Anthony, Catherine T ^b   Hughey, Susan ^b   Gebhardt, Bryan M ^b   Espenan, Gregory D ^b   Woltering, Eugene A ^a  

^a New Orleans Civil Service   (United States)

^b NONE

Author keywords

DNA binding; Endocytosis; In situ radiotherapy; Membrane receptor; Somatostatin

Indexed keywords

IODINE 125; MEMBRANE RECEPTOR; OCTREOTIDE; PENTETREOTIDE IN 111; SOMATOSTATIN 14; SOMATOSTATIN DERIVATIVE;

ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; DNA BINDING; DRUG ACCUMULATION; DRUG BINDING; DRUG DEGRADATION; DRUG DISTRIBUTION; DRUG UPTAKE; ENDOCYTOSIS; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL;

CELL NUCLEUS; DNA, NEOPLASM; HUMANS; INDIUM; NEUROBLASTOMA; ORGANOMETALLIC COMPOUNDS; PROTEIN BINDING; SOMATOSTATIN; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0033912674     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Reisine T, Bell GI. Molecular biology of somatostatin receptors. Endocr Rev. 1995;16:427-442.
2. Patel YC, Greenwood MT, Warszynska A, Panetta R, Srikant CB. All five cloned human somatostatin receptors are functionally coupled to adenyl cyclase. Biochem Biophys Res Commun. 1994;198:605-612.
3. Lamberts SW, Krenning EP, Klijn JG, Reubi JC. The clinical use of somatostatin analogs in the treatment of cancer. Baillieres Clin Endocrinol Metab. 1990;4: 29-49.
4. Reubi JC, Laissue J, Krenning EP, Lamberts SW. Somatostatin receptors in human cancer: incidence, characteristics, functional correlates and clinical implications. J Steroid Biochem Mol Biol. 1992;43:27-35.
5. Wollering EA, O'Dorisio MS, O'Dorisio TM. The role of radiolabeled somatostatin analogs in the management of cancer patients. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. Principles and Practice of Oncology. Philadelphia, PA: Lippincott-Raven; 1995:1-16.
6. 111In-pentetreotide: initial observations and future directions. Cancer J Sci Am. 1998;4:94-102.
7. Meyers MO, Anthony CT, O'Dorisio TM, et al. Multiply radioiodinated somatostatin analogs induce receptor specific cytotoxicity. J Surg Res. 1998;76:154-158.
8. 1)-octreotide: a case history. Ann NY Acad Sci. 1994;733:496-506.
9. Sahu SK, Baranowska-Kortylewicz J, Taube RA, Adelstein SJ, Kassis AL. Strand breaks after the decay of iodine-125 in proximity to plasmid pBR322 DNA. Radiat Res. 1997;147:401-408.
10. Humm JL, Howell RW, Rao DV. Dosimetry of Auger-electron emitting radionuclides: report no. 3 of AAPM Nuclear Medicine Task Group No. 6. Med Phys. 1994;21:1901-1915.
11. Amherdt M, Patel YC, Orci L. Binding and internalizalion of somatostatin, insulin, and glucagon by cultured rat islet cells. J Clin Invest. 1989;84:412-417.
12. Hornick CA, Hui DY, DeLamatre JG. A role for retrosomes in intracellular cholesterol transport from endosomes to the plasma membrane. Am J Physiol. 1997;273:C1075-C1081.
13. Brown WJ, Farquhar MG. The mannose phosphate receptor for lysosomal enzymes is concentrated in cis golgi cisternae. Cell. 1984;36:295-307.
14. Apodaca G, Katz LA, Mostov KE. Receptor mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. J Cell Biol. 1994;125:67-86.
15. Roth A, Kreienkamp HJ, Nehring RB, Roosterman D, Meyerhof W, Richter D. Endocytosis of the rat somatostatin receptors: subtype discrimination, ligand specificity, and delineation of carboxy-terminal positive and negative sequence motifs. DNA Cell Biol. 1997;16:111-119.
16. Nouel D, Gaudriault G, Houle M, et al. Differential internalization of somatostatin in COS-7 cells transfected with SST-1 and SST-2 receptor subtypes: a confocal microscopic study using novel fluorescent somatostatin derivatives. Endocrinology. 1997;138:296-306.
17. Koenig, JA, Edwardson JM, Humphrey PP. Somatostatin receptors in Neuro2A neuroblastoma cells: ligand internalization. Br J Pharmacol. 1997;120:52-59.
18. Hukovic N, Panetta R, Kumar U, Patel YC. Agonist-dependent regulation of cloned human somatostatin receptor type sw 1-5 (hSSTR1-5): subtype selective intemalization or upregulation. Endocrinology. 1996;137:4046-4049.
19. O'Dorisio MS, Chen F, O'Dorisio TM, Wrang D, Qualman SJ. Characterization of somatostatin receptors on human neuroblastoma tumors. Cell Growth Differ. 1991;5:1-8.
20. Khoury G, Lai CJ. Preparation of simian virus 40 and its DNA. In: Jakoby WB, Pastan IM, eds. Methods in Enzymology. Vol 57. New York, NY: Academic Press; 1978:404-412.
21. Emmelot PC, Bos J, Benedetti EL, Rumke PH. Studies on plasma membranes: 1. Chemical composition and enzyme content of plasma membranes isolated from rat liver. Biochem Biophys Acta. 1964;90:126-145.
22. Findlay JG, Levy A, Marsh CA. Inhibition of glycosidases by aldonolactones of corresponding configuration. Biochem J. 1958;69:467-476.
23. Woltering EA, O'Dorisio MS, Murphy WA, et al. Synthesis and characterization of multiply-tyrosinated, multiply-iodinated somatostatin analogs. J Peptide Res. 1999;53:201-213.
24. Viguerie N, Esteve JP, Susiini C, Vaysse N, Ribet A. Processing of receptor-bound somatostatin: internalization and degradation by pancreatic acini. Am J Physiol. 1987;252:G535-G542.
25. Morel G, Pelletier G, Heisler S. Internalization and distribution of radiolabeled somatostatin-28 in mouse anterior pituitary tumor cells. Endocrinology. 1986;119: 1972-1979.
26. Morel G. Internalization and nuclear localization of peptide hormones. Biochemical Pharm. 1994;47:63-76.
27. Espenan GD, Nelson JA, Fisher DR, et al. Experiences with high-dose radiopeptide therapy: the health physics perspective. Health Phys. 1999;76:225-235.