Platelet-activating factor increases prostaglandin E2 release from astrocyte-enriched cortical cell cultures

Brain Research

Volumn 946, Issue 1, 2002, Pages 87-95

  Teather, Lisa A ^a   Lee, Robert K K ^a   Wurtman, Richard J ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Alzheimer's disease; Astrocyte; Inflammation; Phospholipase; Platelet activating factor; Prostaglandin

Indexed keywords

PHOSPHOLIPID; PROSTAGLANDIN E2; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR DERIVATIVE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BINDING SITE; BRAIN CELL; CELL CULTURE; CELL LEVEL; CELL SECRETION; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HYDROLYSIS; MOBILIZATION; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; RECEPTOR BLOCKING; TIME;

ANIMALS; ARACHIDONIC ACID; ASTROCYTES; BINDING SITES; CELLS, CULTURED; CEREBRAL CORTEX; DINOPROSTONE; DITERPENES; DRUG SYNERGISM; FEMALE; GINKGOLIDES; LACTONES; OSMOLAR CONCENTRATION; PHOSPHOLIPID ETHERS; PLATELET ACTIVATING FACTOR; PYRIDINIUM COMPOUNDS; RATS; SOLVENTS;

EID: 0037047460     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)02866-4     Document Type: Article

References (43)

1. Interaction between neurone and microglia mediated by platelet-activating factor
2. Increased expression of the proinflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
3. PAF stimulates cAMP formation in P388D1 macrophage-like cells via the formation and secretion of prostaglandin E2 in an autocrine fashion
4. Platelet-activating factor is a synapse messenger and an intracellular modulator of gene expression
5. Phospholipid degradation, second messengers and activation of cell signaling genes
6. Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene
7. Bioactive lipids in excitatory neurotransmission and neuronal plasticity
8. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes
9. Characterization of platelet-activating factor (PAF) receptor in the rat brain
10. 2+ in hippocampal neurons
11. Metabolic fate of platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-3-phosphocholine) and lyso-PAF (1-O-alkyl-2-lyso-sn-glycerol-3-phosphocholine) in FRTL5 cells
12. Inverse association of anti-inflammatory treatments and Alzheimer's disease: Initial results of a co-twin control study
13. Recombinant human interleukin 1β induces production of prostaglandins in primary human fetal astrocytes and immortalized human fetal astrocyte cultures
14. PAF-acetylhydrolases
15. Arachidonic acid eicosanoids as targets and effectors in second messenger interactions
16. Inhibition of cyclooxygenase-2 protects motor neurons in an organotypic model of amyotrophic lateral sclerosis
17. Properties and regulation of microsomal PAF-synthesizing enzymes in rat brain cortex
18. Lysophospholipids trigger calcium signals but not DNA synthesis in cortical astrocytes
19. Characteristics of endothelial cells derived from the blood-brain barrier and of astrocytes in culture
20. Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia
21. Ionic and GTP regulation of binding of platelet-activating factor to receptors and platelet-activating factor-induced activation of GTPase in rabbit platelet membranes
22. Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain
23. Metabolic glutamate receptors increase amyloid precursor protein processing in astrocytes: Inhibition by cyclic AMP
24. Transforming growth factor β1 regulates the expression of cyclooxygenase in cultured cortical astrocytes and neurons
25. Platelet-activating factor is a messenger in the electroconvulsive shock-induced transcriptional activation of c-fos and zif-268 in hippocampus
26. Distinct platelet-activating factor binding sites in synaptic endings and in intracellular membranes of rat cerebral cortex
27. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
28. Anti-inflammatory drugs and Alzheimer's disease
29. 2 in rat cultured astrocytes
30. A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation process
31. Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate
32. Arachidonic acid cyclo and lipoxygenase pathways in astroglial cells
33. Reactive astrocytes: Cellular and molecular cues to biological function
34. TWEAK stimulation of astrocytes and the proinflammatory consequences
35. Platelet-activating factor and its analogs: Metabolic pathways and related intracellular pathways
36. Platelet-activating factor stimulates a Fos/Jun/AP-1 transcriptional signaling system in human neuroblastoma cells
37. 2) is expressed in human brain astrocytes
38. 2) immunoreactivity is elevated in Alzheimer's disease brain
39. Regulation of platelet-activating factor (PAF) biosynthesis via coenzyme A-independent transacylase in the macrophage cell line IC-21 stimulated with lipopolysaccharide
40. Stimulation of platelet-activating factor synthesis by a nonmetabolizable bioactive analog of platelet-activating factor and influence of arachidonic acid metabolites
41. Production of eicosanoids derived from 20;4n-6 and 20:5n-3 in primary cultures of turbot (Scopthalmus maximus) brain astrocytes in response to platelet-activating factor, substance P and interleukin-1β
42. Cyclooxygenases 1 and 2
43. i protein