Effect of structural parameters of peptides on dimer formation and highly oxidized side products in the oxidation of thiols of linear analogues of human β-defensin 3 by DMSO

Journal of Peptide Science

Volumn 15, Issue 2, 2009, Pages 95-106

  Liu, Shouping ^a   Zhou, Lei ^a,b   Chen, Liyan ^a   Dastidar, Shubhra Ghosh ^c   Verma, Chandra ^c   Li, Jing ^a,b   Tan, Donald ^a,b,d   Beuerman, Roger ^a,b  

^a SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c BIOINFORMATICS INSTITUTE   (Singapore)

^d SINGAPORE NATIONAL EYE CENTRE   (Singapore)

Author keywords

Antimicrobial peptides; Dimers; DMSO; Highly oxidized side products; Human defensin 3 (hBD3); Molecular hydrophobicity; Molecular modelling

Indexed keywords

BETA DEFENSIN; CYSTEINE; DIMER; DIMETHYL SULFOXIDE; DISULFIDE; HOMODIMER; PEPTIDE DERIVATIVE; THIOL DERIVATIVE; BETA DEFENSIN 3, HUMAN; BETA-DEFENSIN 3, HUMAN; PEPTIDE; SOLVENT;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANALYTICAL PARAMETERS; ARTICLE; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR WEIGHT; OXIDATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METHODOLOGY; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN QUATERNARY STRUCTURE;

PIERIDAE;

AMINO ACID SEQUENCE; BETA-DEFENSINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; DIMERIZATION; DIMETHYL SULFOXIDE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PEPTIDES; PROTEIN STRUCTURE, QUATERNARY; SOLVENTS; SULFHYDRYL COMPOUNDS;

EID: 61449100509     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1100     Document Type: Article

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