γδ T Lymphocyte Homeostasis Is Negatively Regulated by β2-Microglobulin

Journal of Immunology

Volumn 182, Issue 4, 2009, Pages 1892-1900

  French, Jena D ^b   Roark, Christina L ^c   Born, Willi K ^a   O'Brieny, Rebecca L ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Beacon Biotechnology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; CYTOKINE RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2A; PROTEIN BCL 2; PROTEIN LY49; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VGAMMA4 T LYMPHOCYTE RECEPTOR; VGAMMA5 T LYMPHOCYTE RECEPTOR; INTERLEUKIN RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD8+ GAMMA DELTA T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; GAMMA DELTA T LYMPHOCYTE; HOMEOSTASIS; LYMPHOCYTE PROLIFERATION; MOUSE; NK1.1+ GAMMA DELTA T LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; ANIMAL; BIOSYNTHESIS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IMMUNOLOGY; MALE; METABOLISM; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; BETA 2-MICROGLOBULIN; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HOMEOSTASIS; MALE; MICE; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, INTERLEUKIN; T-LYMPHOCYTE SUBSETS;

EID: 61449086337     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803165     Document Type: Article

References (55)

1. Hayday, A., and R. Tigelaar. 2003. Immunoregulation in the tissues by γδ T cells. Nat. Rev. Immunol. 3: 233-242.
2. French, J. D., C. L. Roark, W. K. Born, and L. R. O'Brien. 2005. γδ T cell homeostasis is established in competition with αβ T cells and NK cells. Proc. Natl. Acad. Sci. USA 102: 14741-14746.
3. Kirberg, J., A. Berns, and H. von Boehmer. 1997. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J. Exp. Med. 186:1269 -1275.
4. Tanchot, C., F. A. Lemonnier, B. Perarnau, A. A. Freitas, and B. Rocha. 1997. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276: 2057-2062.
5. Chien, Y. H., R. Jores, and M. P. Crowley. 1996. Recognition by γδ T cells. Annu. Rev. Immunol. 14: 511-532.
6. Groh, V., A. Steinle, S. Bauer, and T. Spies. 1998. Recognition of stress-induced MHC molecules by intestinal epithelial γδ T cells. Science 279: 1737-1740.
7. Wu, J., V. Groh, and T. Spies. 2002. T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells. J. Immunol. 169: 1236-1240.
8. Weintraub, B. C., M. R. Jackson, and S. M. Hedrick. 1994. γδ T cells can recognize nonclassical MHC in the absence of conventional antigenic peptides. J. Immunol. 153: 3051-3058.
9. Tough, D. F., and J. Sprent. 1998. Lifespan of γδ T cells. J. Exp. Med. 187: 357-365.
10. Crowley, M. P., A. M. Fahrer, N. Baumgarth, J. Hampl, I. Gutgemann, L. Teyton, and Y. Chien. 2000. A population of murine γδ T cells that recognize an inducible MHC class Ib molecule. Science 287: 314-316.
11. Bucy, R. P., C. L. Chen, and M. D. Cooper. 1989. Tissue localization and CD8 accessory molecule expression of T γδ cells in humans. J. Immunol. 142: 3045-3049.
12. Deusch, K., F. Luling, K. Reich, M. Classen, H. Wagner, and K. Pfeffer. 1991. A major fraction of human intraepithelial lymphocytes simultaneously expresses the γδ T cell receptor, the CD8 accessory molecule and preferentially uses the Vδ1 gene segment. Eur. J. Immunol. 21: 1053-1059.
13. Sato, K., K. Ohtsuka, H. Watanabe, H. Asakura, and T. Abo. 1993. Detailed characterization of γδ T cells within the organs in mice: classification into three groups. Immunology 80: 380-387.
14. Poccia, F., B. Cipriani, S. Vendetti, V. Colizzi, Y. Poquet, L. Battistini, M. Lopez-Botet, J. J. Fournie, and M. L. Gougeon. 1997. CD94/NKG2 inhibitory receptor complex modulates both anti-viral and anti-tumoral responses of polyclonal phosphoantigen-reactive Vγ9Vδ2 T lymphocytes. J. Immunol. 159: 6009-6017.
15. + γδ T cells. Immunology 102: 24-30.
16. Toyama-Sorimachi, N., Y. Taguchi, H. Yagita, F. Kitamura, A. Kawasaki, S. Koyasu, and H. Karasuyama. 2001. Mouse CD94 participates in Qa-1-mediated self recognition by NK cells and delivers inhibitory signals independent of Ly-49. J. Immunol. 166: 3771-3779.
17. Van Beneden, K., A. De Creus, F. Stevenaert, V. Debacker, J. Plum, and G. Leclercq. 2002. Expression of inhibitory receptors Ly49E and CD94/NKG2 on fetal thymic and adult epidermal TCR Vγ3 lymphocytes. J. Immunol. 168: 3295-3302.
18. Ryan, J. C., J. Turck, E. C. Niemi, W. M. Yokoyama, and W. E. Seaman. 1992. Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. J. Immunol. 149: 1631-1635.
19. Carlyle, J. R., A. M. Jamieson, S. Gasser, C. S. Clingan, H. Arase, and D. H. Raulet. 2004. Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc. Natl. Acad. Sci. USA 101: 3527-3532.
20. Iizuka, K., O. V. Naidenko, B. F. Plougastel, D. H. Fremont, and W. M. Yokoyama. 2003. Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors. Nat. Immunol. 4: 801-807.
21. Battistini, L., G. Borsellino, G. Sawicki, F. Poccia, M. Salvetti, G. Ristori, and C. F. Brosnan. 1997. Phenotypic and cytokine analysis of human peripheral blood γδ T cells expressing NK cell receptors. J. Immunol. 159: 3723-3730.
22. Vance, R. E., A. M. Jamieson, and D. H. Raulet. 1999. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/ NKG2E on mouse natural killer cells. J. Exp. Med. 190: 1801-1812.
23. Sentman, C. L., J. Hackett, Jr., V. Kumar, and M. Bennett. 1989. Identification of a subset of murine natural killer cells that mediates rejection of Hh-1d but not Hh-1b bone marrow grafts. J. Exp. Med. 170: 191-202.
24. Liao, N. S., M. Bix, M. Zijlstra, R. Jaenisch, and D. Raulet. 1991. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253: 199-202.
25. Jamieson, A. M., P. Isnard, J. R. Dorfman, M. C. Coles, and D. H. Raulet. 2004. Turnover and proliferation of NK cells in steady state and lymphopenic conditions. J. Immunol. 172: 864-870.
26. Ranson, T., C. A. Vosshenrich, E. Corcuff, O. Richard, W. Muller, and J. P. Di Santo. 2003. IL-15 is an essential mediator of peripheral NK-cell homeostasis. Blood 101: 4887-4893.
27. Lanier, L. L. 1998. NK cell receptors. Annu. Rev. Immunol. 16: 359-393.
28. + T cells. Curr. Opin. Immunol. 13: 465-470.
29. Brennan, J., G. Mahon, D. L. Mager, W. A. Jefferies, and F. Takei. 1996. Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions. J. Exp. Med. 183: 1553-1559.
30. George, T. C., J. R. Ortaldo, S. Lemieux, V. Kumar, and M. Bennett. 1999. Tolerance and alloreactivity of the Ly49D subset of murine NK cells. J. Immunol. 163: 1859-1867.
31. Shin, S., R. El-Diwany, S. Schaffert, E. J. Adams, K. C. Garcia, P. Pereira, and Y. H. Chien. 2005. Antigen recognition determinants of γδ T cell receptors. Science 308: 252-255.
32. Adams, E. J., Y. H. Chien, and K. C. Garcia. 2005. Structure of a γδ T cell receptor in complex with the nonclassical MHC T22 (see comment). Science 308: 227-231.
33. Roark, C. L., J. D. French, M. A. Taylor, A. M. Bendele, W. K. Born, and R. L. O'Brien. 2007. Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing γδ T cells. J. Immunol. 179: 5576-5583.
34. Yio, X. Y., and L. Mayer. 1997. Characterization of a 180-kDa intestinal epithelial cell membrane glycoprotein, gp180: a candidate molecule mediating T cell-epithelial cell interactions. J. Biol. Chem. 272: 12786-12792.
35. Baccala, R., D. Witherden, R. Gonzalez-Quintial, W. Dummer, C. D. Surh, W. L. Havran, and A. N. Theofilopoulus. 2005. γδ T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors. J. Immunol. 174: 4606-4612.
36. Hill, G. R., J. M. Crawford, K. R. Cooke, Y. S. Brinson, L. Pan, and J. L. Ferrara. 1997. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 90: 3204-3213.
37. Gruber, A., and T. Brocker. 2005. MHC class I-positive dendritic cells (DC) control CD8 T cell homeostasis in vivo: T cell lymphopenia as a prerequisite for DC-mediated homeostatic proliferation of naive CD8 T cells. J. Immunol. 175:201-206.
38. + T cells. Proc. Natl. Acad. Sci. USA 95: 1172-1177.
39. Hanke, T., H. Takizawa, C. W. McMahon, D. H. Busch, E. G. Pamer, J. D. Miller, J. D. Altman, Y. Liu, D. Cado, F. A. Lemonnier, et al. 1999. Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 11: 67-77.
40. Rodgers, J. R., and R. G. Cook. 2005. MHC class Ib molecules bridge innate and acquired immunity. Nat. Rev. Immunol. 5: 459-471.
41. Howcroft, T. K., and D. S. Singer. 2003. Expression of nonclassical MHC class Ib genes: comparison of regulatory elements. Immunol. Res. 27: 1-30.
42. Cardoso, C. S., and M. de Sousa. 2003. HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I. Tissue Antigens 61: 263-275.
43. 2-microglobulin-deficient mice. Immunol. Lett. 39: 105-111.
44. Bowern, N., I. A. Ramshaw, P. Badenoch-Jones, and P. C. Doherty. 1984. Effect of an iron-chelating agent on lymphocyte proliferation. Aust J. Exp. Biol. Med. Sci. 62 (Pt. 6): 743-754.
45. Brock, J. H., T. Mainou-Fowler, and L. M. Webster. 1986. Evidence that transferrin may function exclusively as an iron donor in promoting lymphocyte proliferation. Immunology 57: 105-110.
46. Mainou-Fowler, T., and J. H. Brock. 1985. Effect of iron deficiency on the response of mouse lymphocytes to concanavalin A: the importance of transferrinbound iron. Immunology 54: 325-332.
47. Ernst, B., D. S. Lee, J. M. Chang, J. Sprent, and C. D. Surh. 1999. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 11: 173-181.
48. Goldrath, A. W., and M. J. Bevan. 1999. Selecting and maintaining a diverse T cell repertoire. Nature 402: 255-262.
49. Kieper, W. C., and S. C. Jameson. 1999. Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands. Proc. Natl. Acad. Sci. USA 96: 13306-13311.
50. Matsuda, J. L., L. Gapin, S. Sidobre, W. C. Kieper, J. T. Tan, R. Ceredig, C. D. Surh, and M. Kronenberg. 2002. Homeostasis of Vα14i NKT cells. Nat. Immunol. 3: 966-974.
51. Ranson, T., C. A. Vosshenrich, E. Corcuff, O. Richard, V. Laloux, A. Lehuen, and J. P. Di Santo. 2003. IL-15 availability conditions homeostasis of peripheral natural killer T cells. Proc. Natl. Acad. Sci. USA 100:2663-2668.
52. Dieli, F., N. Gebbia, F. Poccia, N. Caccamo, C. Montesano, F. Fulfaro, C. Arcara, M. R. Valerio, S. Meraviglia, C. Di Sano, et al. 2003. Induction of γδ T lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo. Blood 102: 2310-2311.
53. + T cells in diseasefree survivors following T cell-depleted, partially mismatched, related donor bone marrow transplantation for leukemia. J. Hematother. 5: 503-509.
54. Wilhelm, M., V. Kunzmann, S. Eckstein, P. Reimer, F. Weissinger, T. Ruediger, and H. P. Tony. 2003. γδ T cells for immune therapy of patients with lymphoid malignancies. Blood 102:200 -206.
55. 2-Microglobulin level predicts outcome following autologous hematopoietic stem cell transplantation in patients with multiple myeloma. Transplant. Proc. 39:2893-2897.