Structure-effect relationship in the down-regulation of glutaminase in cultured human cells by phenylarsenic compounds

Toxicology

Volumn 258, Issue 2-3, 2009, Pages 157-163

  Kita, Kayoko ^a   Sato, Motohiro ^a   Suzuki, Toshihide ^a   Ochi, Takafumi ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Diphenylarsinic acid (DPAA); Glutaminase C (GAC); Phenylarsonic acid (PAA); Phenylmethylarsinic acid (PMAA); Phosphate activated glutaminase (PAG)

Indexed keywords

ARSENIC DERIVATIVE; ARSINIC ACID DERIVATIVE; BENZENEARSONIC ACID; BIS(DIPHENYLARSINE)OXIDE; CACODYLIC ACID; DIMETHYLARSINOUS ACID; DIPHENYLARSINIC ACID; DIPHENYLMETHYLARSINE OXIDE; GLUTAMINASE; GLUTAMINASE C; GLUTATHIONE; HYDROXYL GROUP; INORGANIC COMPOUND; PHENYLDIMETHYLARSINE OXIDE; PHENYLMETHYLARSINIC ACID; PHOSPHATE ACTIVATED GLUTAMINASE; TRIPHENYLARSINE; UNCLASSIFIED DRUG;

ARSENIC POISONING; ARTICLE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; JAPAN; METABOLITE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ARSENICALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GLUTAMINASE; HEPATOCYTES; HUMANS; LIVER NEOPLASMS; MOLECULAR STRUCTURE; TIME FACTORS;

EID: 61349182492     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.01.020     Document Type: Article

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