Synergistic effects of basic fibroblast growth factor and insulin on Chinese hamster ovary cells under serum-free conditions

Journal of Bioscience and Bioengineering

Volumn 107, Issue 3, 2009, Pages 312-317

  Liu, Chi Hsien ^a   Wu, Kuo Wei ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Basic fibroblast growth factor; Chinese hamster ovary cells; Insulin; Macrophage colony stimulating factor

Indexed keywords

ANTIAPOPTOTIC; APOPTOTIC; BASIC FIBROBLAST GROWTH FACTOR; BIOTECHNOLOGY INDUSTRIES; CELL CYCLES; CELL LINES; CELL VIABILITIES; CHINESE HAMSTER OVARY CELLS; CHO CELLS; DESIGN AND DEVELOPMENT; GROWTH FACTORS; MAMMALIAN CELLS; MITOGENIC EFFECTS; RECOMBINANT PROTEINS; SERUM-FREE CONDITIONS; SERUM-FREE MEDIAS; STIMULATORY EFFECTS; SYNERGISTIC EFFECTS;

ANIMAL CELL CULTURE; BIOACTIVITY; BODY FLUIDS; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; INSULIN; MACROPHAGES; MAMMALS; MEATS; PEPTIDES;

CELL CULTURE;

ANIMALS; CELL CYCLE; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; CULTURE MEDIA, SERUM-FREE; DRUG SYNERGISM; FIBROBLAST GROWTH FACTOR 2; INSULIN; MACROPHAGE COLONY-STIMULATING FACTOR;

CRICETULUS GRISEUS; MAMMALIA;

EID: 61349143201     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2009.02.001     Document Type: Article

References (38)

1. Fujiwara M., Koizumi S., and Takagi M. Effect of static pressure on intracellular ph of adhesive Chinese hamster ovary cells. J. Biosci. Bioeng. 104 (2007) 510-512
2. De Leon Gatti M., Wlaschin K.F., Nissom M.P., Yap M., and Hu W.S. Comparative transcriptional analysis of mouse hybridoma and recombinant Chinese hamster ovary cells undergoing butyrate treatment. J. Biosci. Bioeng. 103 (2007) 82-91
3. Han Y., Liu X.M., Liu H., Li S.C., Wu B.C., Ye L.L., Wang Q.W., and Chen Z.L. Cultivation of recombinant Chinese hamster ovary cells grown as suspended aggregates in stirred vessels. J. Biosci. Bioeng. 102 (2006) 430-435
4. Omasa T., Tanaka R., Doi T., Ando M., Kitamoto Y., Honda K., Kishimoto M., and Ohtake H. Decrease in antithrombin III fucosylation by expressing GDP-fucose transporter siRNA in Chinese hamster ovary cells. J. Biosci. Bioeng. 106 (2008) 168-173
5. Kim H.J., and Kim H.J. Glycosylation variant analysis of recombinant human tissue plasminogen activator produced in urea-cycle-enzyme-expressing Chinese hamster ovary (CHO) cell line. J. Biosci. Bioeng. 102 (2006) 447-451
6. Liu C.H., and Chen L.H. Promotion of recombinant macrophage colony stimulating factor production by dimethyl sulfoxide addition in Chinese hamster ovary cells. J. Biosci. Bioeng. 103 (2007) 45-49
7. Park H., An S., and Choe T. Change of insulin-like growth factor gene expression in Chinese hamster ovary cells cultured in serum-free media. Biotechnol. Bioproc. Eng. 11 (2006) 319-324
8. Goswami J., Sinskey A.J., Steller H., Stephanopoulos G.N., and Wang D.I.C. Apoptosis in batch cultures of Chinese hamster ovary cells. Biotechnol. Bioeng. 62 (1999) 632-640
9. Zanghi J.A., Fussenegger M., and Bailey J.E. Serum protects protein-free competent chinese hamster ovary cells against apoptosis induced by nutrient deprivation in batch culture. Biotechnol. Bioeng. 64 (1999) 108-119
10. Sun O.H., and Lee G.M. Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture. Biotechnol. Bioeng. 99 (2008) 678-685
11. Ifandi V., and Al-Rubeai M. Regulation of cell proliferation and apoptosis in CHO-K1 cells by the coexpression of c-Myc and Bcl-2. Biotechnol. Prog. 21 (2005) 671-677
12. Sunstrom N.A.S., Gay R.D., Wong D.C., Kitchen N.A., Deboer L., and Gray P.P. Insulin-like growth factor-I and transferrin mediate growth and survival of Chinese hamster ovary cells. Biotechnol. Prog. 16 (2000) 698-702
13. Adamson L., and Walum E. Insulin and IGF-1 mediated inhibition of apoptosis in CHO cells grown in suspension in a protein-free medium. ATLA Alter. Lab. Animal 35 (2007) 349-352
14. Hunt S.M.N., Pak S.C.O., Bridges M.W., Gray P.P., and Sleigh M.J. Chinese hamster ovary cells produce sufficient recombinant insulin-like growth factor I to support growth in serum-free medium. Cytotechnology 24 (1997) 55-64
15. Liu C.H., and Chang T.Y. Rational development of serum-free medium for Chinese hamster ovary cells. Process Biochem. 41 (2006) 2314-2319
16. Sakai K., Hayashi C., Yamaji H., and Fukuda H. Use of nonionic surfactants for effective supply of phosphatidic acid in serum-free culture of Chinese hamster ovary cells. J. Biosci. Bioeng. 92 (2001) 256-261
17. Hayashi C., Sakai K., Yamaji H., and Fukuda H. Comparative study on delivery of phosphatidic acid to serum-free culture of Chinese hamster ovary cells. J. Biosci. Bioeng. 96 (2003) 196-198
18. Darfler F.J. Preparation and use of lipid microemulsions as nutritional supplements for culturing mammalian cells. In Vitro Cell Dev. Biol. - Animal 26 (1990) 779-783
19. Bertrand F., Desbois-Mouthon C., Cadoret A., Prunier C., Robin H., Capeau J., Atfi A., and Cherqui G. Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase. J. Biol. Chem. 274 (1999) 30596-30602
20. Matsuoka N., Ishii K., Akimoto M., Hamada H., Hashimoto N., Miyatake S.I., Hodge Jr. C.J., and Rutka J.T. Overexpression of basic fibroblast growth factor and Bcl-xL with adenoviral vectors protects primarily cultured neurons against glutamate insult. Neurosurgery 50 (2002) 857-863
21. Lynch K., Fernandez G., Pappalardo A., and Peluso J.J. Basic fibroblast growth factor inhibits apoptosis of spontaneously immortalized granulosa cells by regulating intracellular free calcium levels through a protein kinase C8-dependent pathway. Endocrinology 141 (2000) 4209-4217
22. Hsuan S.L., Klintworth H.M., and Xia Z. Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways. J. Neurosci. 26 (2006) 4481-4491
23. Zhao J., Zhao B., Du A., Zhao Q., and Miao J. Effects of novel safrole oxide derivatives, 1-propyl-3-(3,4-methylenedioxyphenyl)-2-propanol and 1-isopropoxy-3- (3,4-methylenedioxyphenyl)-2-propanol, on apoptosis induced by deprivation of survival factors in vascular endothelial cells. J. Endothelial. Cell Res. 11 (2004) 267-273
24. Wong V.V.T., Ho K.W., and Yap M.G.S. Evaluation of insulin-mimetic trace metals as insulin replacements in mammalian cell cultures. Cytotechnology 45 (2004) 107-115
25. Pratsinis H., and Kletsas D. PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways. Eur. Spine J. 16 (2007) 1858-1866
26. Xiao Z., Kong Y., Yang S., Li M., Wen J., and Li L. Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation. Cell Res. 17 (2007) 73-79
27. Deo D.D., William Axelrad T., Robert E.G., Marcheselli V., Bazan N.G., and Hunt J.D. Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism. J. Biol. Chem. 277 (2002) 21237-21245
28. Crickard K. Basic fibroblast growth factor and receptor expression in human ovarian cancer. Gynecol. Oncol. 55 (1994) 277-284
29. Zhang H., Zhang S., Zhuang H., and Lu F. Cytotoxicity of a novel fibroblast growth factor receptor targeted immunotoxin on a human ovarian teratocarcinoma cell line. Cancer Biother. Radiopharm. 21 (2006) 321-332
30. Hsia E., Richardson T.P., and Nugent M.A. Nuclear localization of basic fibroblast growth factor is mediated by heparan sulfate proteoglycans through protein kinase C signaling. J. Cell Biochem. 88 (2003) 1214-1225
31. Engling A., Backhaus R., Stegmayer C., Zehe C., Seelenmeyer C., Kehlenbach A., Schwappach B., Wegehingel S., and Nickel W. Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells. J. Cell Sci. 115 (2002) 3619-3631
32. Florio T., Yao H., Carey K.D., Dillon T.J., and Stork P.J.S. Somatostatin activation of mitogen-activated protein kinase via somatostatin receptor 1 (SSTR1). Mol. Endocrinol. 13 (1999) 24-37
33. Florio T., Thellung S., Arena S., Corsaro A., Bajetto A., Schettini G., and Stork P.J.S. Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2. J. Physiol. Paris 94 (2000) 239-250
34. Florio T., Arena S., Pattarozzi A., Thellung S., Corsaro A., Villa V., Massa A., Diana F., Spoto G., Forcella S., Damonte G., Filocamo M., Benatti U., and Schettini G. Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis. Mol. Pharm. 63 (2003) 297-310
35. Takahashi T., Ogasawara T., Kishimoto J., Liu G., Asato H., Nakatsuka T., Uchinuma E., Nakamura K., Kawaguchi H., Takato T., and Hoshi K. Synergistic effects of FGF-2 with insulin or IGF-I on the proliferation of human auricular chondrocytes. Cell. Transplant. 14 (2005) 683-693
36. Peehl D.M., Sellers R.G., and Wong S.T. Defined medium for normal adult human prostatic stromal cells. In Vitro Cell Dev. Biol. - Animal 34 (1998) 555-560
37. Bendall S.C., Stewart M.H., Menendez P., George D., Vijayaragavan K., Werbowetski-Ogilvie T., Ramos-Mejia V., Rouleau A., Yang J., Bosse M., Lajoie G., and Bhatia M. IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature 448 (2007) 1015-1021
38. Sanfeliu A., Chung J.D., and Stephanopoulos G. Effect of insulin stimulation on the proliferation and death of Chinese hamster ovary cells. Biotechnol. Bioeng. 70 (2000) 421-427