The hardening phenomenon in irritant contact dermatitis: An interpretative update

Contact Dermatitis

Volumn 60, Issue 3, 2009, Pages 123-130

  Watkins, Shannon A ^a   Maibach, Howard I ^b,c  

^a Columbia College of Physicians and Surgeons ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Accommodation; Contact dermatitis; Hardening; Hyporeactivity; Irritant; Irritant contact dermatitis; Skin hyporeactivity

Indexed keywords

BLOOD VESSEL REACTIVITY; HUMAN; INFLAMMATION; IRRITANT DERMATITIS; PATHOGENESIS; REVIEW; SKIN MANIFESTATION; SKIN PERMEABILITY;

ADAPTATION, PHYSIOLOGICAL; CHRONIC DISEASE; DERMATITIS, ALLERGIC CONTACT; DERMATITIS, IRRITANT; DERMATITIS, OCCUPATIONAL; HAND DERMATOSES; HUMANS; IRRITANTS; OCCUPATIONAL EXPOSURE; SKIN; UNITED STATES; WORKPLACE;

EID: 61349116123     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.1600-0536.2009.01507.x     Document Type: Review

References (35)

1. John S M, Uter W, Schwanitz H J. Relevance of multiparametric skin bioengineering in a prospectively-followed cohort of junior hairdressers. Contact Dermatitis 2000 : 43 : 161 168.
2. Heinemann C, Paschold C, Fluhr J et al. Induction of a hardening phenomenon by repeated application of SLS: analysis of lipid changes in the stratum corneum. Acta Derm Venereol 2005 : 85 : 290 295.
3. de Jongh C M, John S M, Bruynzeel D P et al. Cytokine gene polymorphisms and susceptibility to chronic irritant contact dermatitis. Contact Dermatitis 2008 : 58 : 269 277.
4. Wigger-Alberti W, Krebs A, Elsner P. Experimental irritant contact dermatitis due to cumulative epicutaneous exposure to sodium lauryl sulphate and toluene: single and concurrent application. Br J Dermatol 2000 : 143 : 551 556.
5. Wulfhorst B. Skin hardening in occupational dermatology. In : Handbook of Occupational Dermatology, Kanerva L, Elsner P, Wahlberg J E, Maibach H I (eds Berlin, Springer-Verlag, 2000 : pp. 115 121.
6. Levin C Y, Maibach H I. Irritant contact dermatitis: is there an immunologic component? Int Immunopharmacol 2002 : 2 : 183 189.
7. Slodownik D, Lee A, Nixon R. Irritant contact dermatitis: a review. Australas J Dermatol 2008 : 49 : 10 11.
8. Fartasch M, Schnetz E, Diepgen T L. Characterization of detergent-induced barrier alterations - effect of barrier cream on irritation. J Investig Dermatol Symp Proc 1998 : 3 : 121 127.
9. Grubauer G, Elias P M, Feingold K R. Transepidermal water loss: the signal for recovery of barrier structure and function. J Lipid Res 1989 : 30 : 323 333.
10. Berner B, Wilson D R, Guy R H, Mazzenga G C, Clarke F H, Maibach H I. The relationship of pKa and acute skin irritation in man. Pharm Res 1988 : 5 : 660 663.
11. Berner B, Wilson D R, Steffens R J et al. The relationship between pKa and skin irritation for a series of basic penetrants in man. Fundam Appl Toxicol 1990 : 15 : 760 766.
12. Babu R J, Chatterjee A, Ahaghotu E, Singh M. Percutaneous absorption and skin irritation upon low-level prolonged dermal exposure to nonane, dodecane and tetradecane in hairless rats. Toxicol Ind Health 2004 : 20 : 109 118.
13. Effendy I, Loffler H, Maibach H I. Epidermal cytokines in murine cutaneous irritant responses. J Appl Toxicol 2000 : 20 : 335 341.
14. Eberhard Y, Ortiz S, Ruiz Lascano A, Kuznitzky R, Serra H M. Up-regulation of the chemokine CCL21 in the skin of subjects exposed to irritants. BMC Immunol 2004 : 5 : 7.
15. de Jongh C M, Khrenova L, Verberk M M, Calkoen F, van Dijk F J, Voss H, John S M, Kezic S. Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: a case-control study. Br J Dermatol 2008.
16. McOsker D E, Beck L W. Characteristics of accommodated (hardened) skin. J Invest Dermatol 1967 : 48 : 372 83.
17. van der Valk P G, Maibach H I. A functional study of the skin barrier to evaporative water loss by means of repeated cellophane-tape stripping. Clin Exp Dermatol 1990 : 15 : 180 182.
18. Lammintausta K, Maibach H I, Wilson D. Human cutaneous irritation: induced hyporeactivity. Contact Dermatitis 1987 : 17 : 193 198.
19. Widmer J, Elsner P, Burg G. Skin irritant reactivity following experimental cumulative irritant contact dermatitis. Contact Dermatitis 1994 : 30 : 35 39.
20. Jungersted J M, Hellgren L I, Jemec G B, Agner T. Lipids and skin barrier function - a clinical perspective. Contact Dermatitis 2008 : 58 : 255 262.
21. Pinnagoda J, Tupker R A, Agner T, Serup J. Guidelines for transepidermal water loss (TEWL) measurement. A report from the Standardization Group of the European Society of Contact Dermatitis. Contact Dermatitis 1990 : 22 : 164 178.
22. Tupker R A, Pinnagoda J, Coenraads P J, Nater J P. Susceptibility to irritants: role of barrier function, skin dryness and history of atopic dermatitis. Br J Dermatol 1990 : 123 : 199 205.
23. Turz E, Weltfriend S, Schulze K, Maibach H I. Reaction of cutaneous blood vessels to successive insults: repeated intradermal histamine challenge on normal and irritated human skin. Exog Dermatol 2002 : 1 : 39 44.
24. Moyal D D, Fourtanier A M. Broad-spectrum sunscreens provide better protection from solar ultraviolet-simulated radiation and natural sunlight-induced immunosuppression in human beings. J Am Acad Dermatol 2008 : 58 : S149 S154.
25. Aubin F. Mechanisms involved in ultraviolet light-induced immunosuppression. Eur J Dermatol 2003 : 13 : 515 523.
26. Koehler A M, Maibach H I. Skin hyporeactivity in relation to patch testing. Contact Dermatitis 2000 : 42 : 1 4.
27. De Jongh C M, Verberk M M, Withagen C E, Jacobs J J, Rustemeyer T, Kezic S. Stratum corneum cytokines and skin irritation response to sodium lauryl sulfate. Contact Dermatitis 2006 : 54 : 325 333.
28. Parslew R, Friedmann P S. The irritancy of anthralin is inhibited by repeat applications of a subirritant concentration. Br J Dermatol 1999 : 141 : 469 474.
29. de Jongh C M, Lutter R, Verberk M M, Kezic S. Differential cytokine expression in skin after single and repeated irritation by sodium lauryl sulphate. Exp Dermatol 2007 : 16 : 1032 1040.
30. Raychaudhuri S P, Jiang W Y, Farber E M, Schall T J, Ruff M R, Pert C B. Upregulation of RANTES in psoriatic keratinocytes: a possible pathogenic mechanism for psoriasis. Acta Derm Venereol 1999 : 79 : 9 11.
31. Franzke A. The role of G-CSF in adaptive immunity. Cytokine Growth Factor Rev 2006 : 17 : 235 244.
32. de Jongh C M, Khrenova L, Kezic S, Rustemeyer T, Verberk M M, John S M. Polymorphisms in the interleukin-1 gene influence the stratum corneum interleukin-1 alpha concentration in uninvolved skin of patients with chronic irritant contact dermatitis. Contact Dermatitis 2008 : 58 : 263 268.
33. Tupker R A. Prediction of irritancy in the human skin irritancy model and occupational setting. Contact Dermatitis 2003 : 49 : 61 69.
34. Robinson M K. Intra-individual variations in acute and cumulative skin irritation responses. Contact Dermatitis 2001 : 45 : 75 83.
35. O'Regan G M, Irvine A D. The role of filaggrin loss-of-function mutations in atopic dermatitis. Curr Opin Allergy Clin Immunol 2008 : 8 : 406 410.