메뉴 건너뛰기




Volumn 63, Issue 3, 2009, Pages 202-208

Reversal effect of substituted 1,3-dimethyl-1H-quinoxalin-2-ones on multidrug resistance in adriamycin-resistant K562/A02 cells

Author keywords

K562 A02 cells; Multidrug resistance (MDR); P glycoprotein (P gp); Reversal effect; Substituted 1,3 dimethyl 1H quinoxalin 2 ones

Indexed keywords

1,3 DIMETHYL 1H QUINOXALIN 2 ONE; DOXORUBICIN; GLYCOPROTEIN P; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 61349086677     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2008.07.090     Document Type: Article
Times cited : (10)

References (27)
  • 1
    • 0036224915 scopus 로고    scopus 로고
    • Inhibitors of multidrug resistance to antitumor agents (MDR)
    • Avendano C., and Menendez J.C. Inhibitors of multidrug resistance to antitumor agents (MDR). Curr Med Chem 9 (2002) 159-193
    • (2002) Curr Med Chem , vol.9 , pp. 159-193
    • Avendano, C.1    Menendez, J.C.2
  • 2
    • 0031864689 scopus 로고    scopus 로고
    • Approaches to multidrug resistance reversal
    • Robert J. Approaches to multidrug resistance reversal. Expert Opin Investig Drugs 7 (1998) 929-939
    • (1998) Expert Opin Investig Drugs , vol.7 , pp. 929-939
    • Robert, J.1
  • 3
    • 0035954243 scopus 로고    scopus 로고
    • Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators
    • Aszalos A., Ladanyi A., Bocsi J., and Szende B. Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators. Cancer Lett 167 (2001) 157-162
    • (2001) Cancer Lett , vol.167 , pp. 157-162
    • Aszalos, A.1    Ladanyi, A.2    Bocsi, J.3    Szende, B.4
  • 4
    • 0037400577 scopus 로고    scopus 로고
    • Multidrug resistance modulators PSC 833 and CsA show differential capacity to induce apoptosis in lymphoid leukemia cell lines independently of their MDR phenotype
    • Lopes E.C., Garcia M., Benavides F., Shen J., Conti C.J., Alvarez E., et al. Multidrug resistance modulators PSC 833 and CsA show differential capacity to induce apoptosis in lymphoid leukemia cell lines independently of their MDR phenotype. Leuk Res 27 (2003) 413-423
    • (2003) Leuk Res , vol.27 , pp. 413-423
    • Lopes, E.C.1    Garcia, M.2    Benavides, F.3    Shen, J.4    Conti, C.J.5    Alvarez, E.6
  • 5
    • 37349069575 scopus 로고    scopus 로고
    • Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells
    • Shen F., Chu S., Bence A.K., Bailey B., Xue X., Erickson P.A., et al. Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells. J Pharmacol Exp Ther 324 (2008) 95-102
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 95-102
    • Shen, F.1    Chu, S.2    Bence, A.K.3    Bailey, B.4    Xue, X.5    Erickson, P.A.6
  • 6
    • 0035863315 scopus 로고    scopus 로고
    • In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576
    • Mistry P., Stewart A.J., Dangerfield W., Okiji S., Liddle C., Bootle D., et al. In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576. Cancer Res 61 (2001) 749-758
    • (2001) Cancer Res , vol.61 , pp. 749-758
    • Mistry, P.1    Stewart, A.J.2    Dangerfield, W.3    Okiji, S.4    Liddle, C.5    Bootle, D.6
  • 7
    • 0035865923 scopus 로고    scopus 로고
    • Structure-activity studies of substituted quinoxalinones as multiple-drug-resistance antagonists
    • Lawrence D.S., Copper J.E., and Smith C.D. Structure-activity studies of substituted quinoxalinones as multiple-drug-resistance antagonists. J Med Chem 44 (2001) 594-601
    • (2001) J Med Chem , vol.44 , pp. 594-601
    • Lawrence, D.S.1    Copper, J.E.2    Smith, C.D.3
  • 8
    • 33646887025 scopus 로고    scopus 로고
    • Synthesis of substituted 1,3-dimethyl-1H-quinoxalin-2-ones from aniline derivatives
    • Li X., Wang D., Wu J., and Xu W. Synthesis of substituted 1,3-dimethyl-1H-quinoxalin-2-ones from aniline derivatives. Heterocycles 65 (2005) 2741-2751
    • (2005) Heterocycles , vol.65 , pp. 2741-2751
    • Li, X.1    Wang, D.2    Wu, J.3    Xu, W.4
  • 9
    • 33748446959 scopus 로고    scopus 로고
    • Overexpression of sorcin in multidrug resistant human leukemia cells and its role in regulating cell apoptosis
    • Qi J., Liu N., Zhou Y., Tan Y., Cheng Y., Yang C., et al. Overexpression of sorcin in multidrug resistant human leukemia cells and its role in regulating cell apoptosis. Biochem Biophys Res Commun 349 (2006) 303-309
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 303-309
    • Qi, J.1    Liu, N.2    Zhou, Y.3    Tan, Y.4    Cheng, Y.5    Yang, C.6
  • 10
    • 34447342246 scopus 로고    scopus 로고
    • CJY, an isoflavone, reverses P-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukaemia (K562/DOX) cells
    • Ji B.S., and He L. CJY, an isoflavone, reverses P-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukaemia (K562/DOX) cells. J Pharm Pharmacol 59 (2007) 1011-1015
    • (2007) J Pharm Pharmacol , vol.59 , pp. 1011-1015
    • Ji, B.S.1    He, L.2
  • 11
    • 32144441841 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer cells
    • Pu Y.S., Hsieh M.W., Wang C.W., Liu G.Y., Huang C.Y., Lin C.C., et al. Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer cells. Biochem Pharmacol 71 (2006) 751-760
    • (2006) Biochem Pharmacol , vol.71 , pp. 751-760
    • Pu, Y.S.1    Hsieh, M.W.2    Wang, C.W.3    Liu, G.Y.4    Huang, C.Y.5    Lin, C.C.6
  • 12
    • 33646807161 scopus 로고    scopus 로고
    • Chemosensitizing multiple drug resistance of human carcinoma by bicyclol involves attenuated p-glycoprotein, GST-P and Bcl-2
    • Zhu B., Liu G.T., Zhao Y.M., Wu R.S., and Strada S.J. Chemosensitizing multiple drug resistance of human carcinoma by bicyclol involves attenuated p-glycoprotein, GST-P and Bcl-2. Cancer Biol Ther 5 (2006) 536-543
    • (2006) Cancer Biol Ther , vol.5 , pp. 536-543
    • Zhu, B.1    Liu, G.T.2    Zhao, Y.M.3    Wu, R.S.4    Strada, S.J.5
  • 13
    • 23844445265 scopus 로고    scopus 로고
    • Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells
    • Ji B.S., He L., and Liu G.Q. Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells. Life Sci 77 (2005) 2221-2232
    • (2005) Life Sci , vol.77 , pp. 2221-2232
    • Ji, B.S.1    He, L.2    Liu, G.Q.3
  • 14
    • 34848879536 scopus 로고    scopus 로고
    • Lipid excipients peceol and gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within caco-2 cells
    • Sachs-Barable K., Thamboo A., Lee S.D., and Wasan K.M. Lipid excipients peceol and gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within caco-2 cells. J Pharm Pharm Sci 10 (2007) 319-331
    • (2007) J Pharm Pharm Sci , vol.10 , pp. 319-331
    • Sachs-Barable, K.1    Thamboo, A.2    Lee, S.D.3    Wasan, K.M.4
  • 15
    • 16244371036 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein function and expression by kaempferol and quercetin
    • Limtrakul P., Khantamat O., and Pintha K. Inhibition of P-glycoprotein function and expression by kaempferol and quercetin. J Chemother 17 (2005) 86-95
    • (2005) J Chemother , vol.17 , pp. 86-95
    • Limtrakul, P.1    Khantamat, O.2    Pintha, K.3
  • 16
    • 35348993755 scopus 로고    scopus 로고
    • Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells
    • Kim S.Y., Kim D.H., Han S.J., Hyun J.W., and Kim H.S. Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells. Biochem Pharmacol 74 (2007) 1642-1651
    • (2007) Biochem Pharmacol , vol.74 , pp. 1642-1651
    • Kim, S.Y.1    Kim, D.H.2    Han, S.J.3    Hyun, J.W.4    Kim, H.S.5
  • 17
    • 34347374838 scopus 로고    scopus 로고
    • Comparison of five methods for determination of total plasma protein concentration
    • Okutucu B., Dincer A., Habib O., and Zihnioqlu F. Comparison of five methods for determination of total plasma protein concentration. J Biochem Biophys Methods 70 (2007) 709-711
    • (2007) J Biochem Biophys Methods , vol.70 , pp. 709-711
    • Okutucu, B.1    Dincer, A.2    Habib, O.3    Zihnioqlu, F.4
  • 18
    • 12544258857 scopus 로고    scopus 로고
    • Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux
    • Riganti C., Miraglia E., Viarisio D., Costamagna C., Pescarmona G., Ghigo D., et al. Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux. Cancer Res 65 (2005) 516-525
    • (2005) Cancer Res , vol.65 , pp. 516-525
    • Riganti, C.1    Miraglia, E.2    Viarisio, D.3    Costamagna, C.4    Pescarmona, G.5    Ghigo, D.6
  • 19
    • 1542268189 scopus 로고    scopus 로고
    • Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein
    • Lee B.D., Li Z., French K.J., French K.J., Zhuang Y., Xia Z., et al. Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem 47 (2004) 1413-1422
    • (2004) J Med Chem , vol.47 , pp. 1413-1422
    • Lee, B.D.1    Li, Z.2    French, K.J.3    French, K.J.4    Zhuang, Y.5    Xia, Z.6
  • 20
    • 0842348985 scopus 로고    scopus 로고
    • Development of a syngeneic in vivo tumor model and its use in evaluating a novel P-glycoprotein modulator, PGP-4008
    • Lee B.D., French K.J., Zhuang Y., and Smith C.D. Development of a syngeneic in vivo tumor model and its use in evaluating a novel P-glycoprotein modulator, PGP-4008. Oncol Res 14 (2003) 49-60
    • (2003) Oncol Res , vol.14 , pp. 49-60
    • Lee, B.D.1    French, K.J.2    Zhuang, Y.3    Smith, C.D.4
  • 21
    • 0028034463 scopus 로고
    • Expression of the multidrug resistance-associated protein (MRP) gene in human lung tumours and normal tissue as determined by in situ hybridization
    • Thomas G.A., Barrand M.A., Stewart S., Rabbitts P.H., Williams E.D., and Twentyman P.R. Expression of the multidrug resistance-associated protein (MRP) gene in human lung tumours and normal tissue as determined by in situ hybridization. Eur J Cancer 30A (1994) 1705-1709
    • (1994) Eur J Cancer , vol.30 A , pp. 1705-1709
    • Thomas, G.A.1    Barrand, M.A.2    Stewart, S.3    Rabbitts, P.H.4    Williams, E.D.5    Twentyman, P.R.6
  • 22
    • 0028025021 scopus 로고
    • Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells
    • Abbaszadegan M.R., Futscher B.W., Klimecki W.T., List A., and Dalton W.S. Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells. Cancer Res 54 (1994) 4676-4679
    • (1994) Cancer Res , vol.54 , pp. 4676-4679
    • Abbaszadegan, M.R.1    Futscher, B.W.2    Klimecki, W.T.3    List, A.4    Dalton, W.S.5
  • 24
    • 0042167430 scopus 로고    scopus 로고
    • P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement
    • Varma M.V., Ashokraj Y., Dey C.S., and Panchagnula R. P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement. Pharmacol Res 48 (2003) 347-349
    • (2003) Pharmacol Res , vol.48 , pp. 347-349
    • Varma, M.V.1    Ashokraj, Y.2    Dey, C.S.3    Panchagnula, R.4
  • 25
    • 0030003644 scopus 로고    scopus 로고
    • Sensitive and rapid bioassay for analysis of P-glycoprotein-inhibiting activity of chemosensitizers in patient serum
    • Lehnert M., de Giuli R., and Twentyman P.R. Sensitive and rapid bioassay for analysis of P-glycoprotein-inhibiting activity of chemosensitizers in patient serum. Clin Cancer Res 2 (1996) 403-410
    • (1996) Clin Cancer Res , vol.2 , pp. 403-410
    • Lehnert, M.1    de Giuli, R.2    Twentyman, P.R.3
  • 26
    • 16244384633 scopus 로고    scopus 로고
    • A novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux
    • Vanhuyse M., Kluza J., Tardy C., Otero G., Cuevas C., Bailly C., et al. A novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux. Cancer Lett 221 (2005) 165-175
    • (2005) Cancer Lett , vol.221 , pp. 165-175
    • Vanhuyse, M.1    Kluza, J.2    Tardy, C.3    Otero, G.4    Cuevas, C.5    Bailly, C.6
  • 27
    • 0035371207 scopus 로고    scopus 로고
    • Modulation by LY335979 of P-glycoprotein function in multidrug-resistant cell lines and human natural killer cells
    • Green L.J., Marder P., and Slapak C.A. Modulation by LY335979 of P-glycoprotein function in multidrug-resistant cell lines and human natural killer cells. Biochem Pharmacol 6 (2001) 1393-1399
    • (2001) Biochem Pharmacol , vol.6 , pp. 1393-1399
    • Green, L.J.1    Marder, P.2    Slapak, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.