Investigation of hepatic gluconeogenesis pathway in non-diabetic Asian Indians with non-alcoholic fatty liver disease using in vivo (31P) phosphorus magnetic resonance spectroscopy

Atherosclerosis

Volumn 203, Issue 1, 2009, Pages 291-297

  Sharma, Rajeev ^a   Sinha, Sanjeev ^a   Danishad, K A ^a   Vikram, Naval K ^a   Gupta, Arun ^a   Ahuja, Vineet ^a   Jagannathan, N R ^a   Pandey, R M ^a   Misra, Anoop ^a,b  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b Diabetes Foundation India New Delhi   (India)

Author keywords

Chemical shift imaging; Non alcoholic fatty liver; Phosphomonoesters; Phosphorus magnetic resonance spectroscopy; Short insulin tolerance test

Indexed keywords

ADENOSINE TRIPHOSPHATE; PHOSPHATE; PHOSPHORUS 31; RECOMBINANT HUMAN INSULIN;

ADULT; ANTHROPOMETRY; ARTICLE; BODY FAT; BODY MASS; CONTROLLED STUDY; DISEASE PREDISPOSITION; FATTY LIVER; GLUCONEOGENESIS; HUMAN; HYPERGLYCEMIA; INDIAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; MAJOR CLINICAL STUDY; OBESITY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; ULTRASOUND; WAIST CIRCUMFERENCE;

ADULT; ANTHROPOMETRY; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FATTY LIVER; GLUCONEOGENESIS; GLUCOSE TOLERANCE TEST; HUMANS; INDIA; INSULIN RESISTANCE; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; PHOSPHORUS ISOTOPES;

EID: 60949101697     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.06.016     Document Type: Article

References (31)

1. Andersen T., and Gluud C. Liver morphology in morbid obesity: a literature study. Int J Obes 8 (1984) 97-106
2. Cairns S.R., and Peters T.J. Biochemical analysis of hepatic lipid in alcoholic, diabetic and control subjects. Clin Sci 65 (1983) 645
3. Pagano G., Pacini G., Musso G., et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association. Hepatology 35 (2002) 367-372
4. Hassan A.Y., Ibrahim E.M., Muhim F.A., Nabhan A.A., and Chammas M.Y. Fatty infiltration of liver. Analysis of prevalence, radiological and clinical features and influence on patient management. Br J Radiol 65 (1992) 774-778
5. Dixon J.B., Bhathal P.S., and Brien PE O. Nonalcoholic fatty liver disease: predictors of non-alcoholic steatohepatitis and liver fibrosis in severely obese. Gastroenterology 121 1 (2001) 91-100
6. Sanyal A.J., Campbell-Sargent C., Mirshahi F., et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 120 5 (2001) 1183-1192
7. Gupta R., and Misra A. Type 2 diabetes in India: regional disparities. Br J Diab Vasc Dis 7 1 (2007) 12-16
8. Misra, and Vikram. Clinical and pathophysiological consequences of abdominal adiposity and abdominal adipose tissue depots. Nutrition 19 5 (2003) 457-466
9. Misra A., Misra R., Wijesuriya M., and Banerjee D. The metabolic syndrome in south Asians: continuing escalation & possible solutions. Indian J Med Res 125 3 (2007) 345-354
10. Garg A., and Misra A. Editorial: hepatic steatosis, insulin resistance, and adipose tissue disorders. J Clin Endocrinol Metab 87 7 (2002) 3019-3022
11. Misra A. Insulin resistance syndrome: current perspective and its relevance in Indians. Indian Heart J 50 (1998) 385-395
12. Misra A., Chaudhary D., Vikram N.K., et al. Insulin resistance and clustering of atherogenic risk factors in women belonging to low socio-economic strata in urban slums of North India. Diabetes Res Clin Pract 56 (2002) 73-75
13. Misra A., and Vikram N.K. Insulin resistance syndrome (metabolic syndrome) and obesity in Asian Indians: evidence and implications. Nutrition 20 5 (2004) 482-491
14. Misra A., Khurana L., Vikram N.K., Goel A., and Wasir J.S. Metabolic syndrome in children: current issues and South Asian perspective. Nutrition 23 11-12 (2007) 895-910
15. Felig P., Sherwin R.S., Soman V., et al. Hormonal interactions in the regulation of blood glucose. Recent Prog Horm Res 35 (1979) 501-532
16. 31P magnetic resonance spectroscopy in vivo. Clin Sci (Lond) 98 2 (2000) 167-174
17. 13C MRS without proton decoupling. Acta Radiol 38 6 (1997) 998-1002
18. 31PMRS. Gut 49 (2001) 557-564
19. Dudeja V., Misra A., Pandey R.M., Devina G., Kumar G., and Vikram N.K. Body mass index does not accurately predict overweight in Asian Indians in Northern India. Br J Nutr 86 (2001) 105-112
20. National Diabetes Data Group. Classification and diagnosis of diabetes and other categories of glucose intolerance. Diabetes 28 (1979) 1039-1057
21. Friedwald W.T., Levy R.I., and Frederickson D.S. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifugation. Clin Chem 18 (1972) 499-502
22. Grundy S.M., Cleeman J.I., Bairey Merz C.N., et al. Implication of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation 110 (2004) 227-239
23. Monzillo L.U., and Hamdy O. Evaluation of insulin sensitivity in clinical practice and in research setting. Nutr Rev 61 12 (2003) 397-412
24. Chen C.C., Wang T.Y., Hsu S.Y., Chen R.H., Chang C.T., and Chen S.J. Is the short insulin tolerance test safe and reproducible?. Diabet Med 15 11 (1998) 924-927
25. Vikram N.K., Misra A., Dwivedi M., et al. Correlations of C-reactive protein levels with anthropometric profile, percentage of body fat and lipids in healthy adolescents and young adults in urban North India. Atherosclerosis 168 (2003) 305-313
26. International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. Available at http://www.idf.org/webdata/docs/IDF_Metasyndrome_definition.pdf. Accessed June 2007.
27. Corbin R., Ryner L.N., Singh H., and Minuk G.Y. Quantitative hepatic phosphorus-31 magnetic resonance spectroscopy in compensated and decompensated cirrhosis. Am J Physiol Gastrointest Liver Physiol 287 (2004) G379-G384
28. 31P nuclear magnetic resonance spectroscopy. Clin Sci (Lond) 78 (1990) 33-38
29. Leij-Halfwerk S., van den Berg J.W., Sijens P.E., Wilson J.H., Oudkerk M., and Dagnelie P.C. Altered hepatic gluconeogenesis during l-alanine infusion in weight-losing lung cancer patients as observed by phosphorus magnetic resonance spectroscopy and turnover measurements. Cancer Res 60 3 (2000) 618-623
30. 31P magnetic resonance spectroscopy. Liver Int 28 5 (2008) 675-681
31. Cortez-Pinto H., Chatham J., Chacko V.P., Arnold C., Rashid A., and Diehl A.M. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 282 (1999) 1659-1664