The calcium channel blocker cilnidipine selectively suppresses hypoxia-inducible factor 1 activity in vascular cells

European Journal of Pharmacology

Volumn 606, Issue 1-3, 2009, Pages 130-136

  Oda, Seiko ^a   Oda, Tomoyuki ^b   Takabuchi, Satoshi ^a   Nishi, Kenichiro ^c   Wakamatsu, Takuhiko ^a   Tanaka, Tomoharu ^a   Adachi, Takehiko ^d   Fukuda, Kazuhiko ^a   Nohara, Ryuji ^d   Hirota, Kiichi ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KANSAI MEDICAL UNIVERSITY   (Japan)

^d Kitano Hospital   (Japan)

Author keywords

Calcium channel blocker; Hypoxia; Hypoxia inducible factor 1 (HIF 1); Smooth muscle cell; Translation; Vascular endothelial cell

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; CILNIDIPINE; DILTIAZEM; EFONIDIPINE; HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; NIFEDIPINE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN KINASE B; VERAPAMIL;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG INHIBITION; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL LINE, TUMOR; DIHYDROPYRIDINES; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INTRACELLULAR SPACE; OXYGEN; STRESS, PHYSIOLOGICAL;

EID: 60949097457     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.01.012     Document Type: Article

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