The leucine-responsive regulatory protein, Lrp, modulates microcin J25 intrinsic resistance in Escherichia coli by regulating expression of the YojI microcin exporter

Journal of Bacteriology

Volumn 191, Issue 4, 2009, Pages 1343-1348

  Socías, Sergio B ^a,b   Vincent, Paula A ^a,b   Salomón, Raúl A ^a,b  

^a Instituto Superior de Investigaciones Biologicas   (Argentina)

^b UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CARRIER PROTEIN; LEUCINE; LEUCINE RESPONSIVE REGULATORY PROTEIN; MICROCIN J25; POLYPEPTIDE ANTIBIOTIC AGENT; RNA POLYMERASE; UNCLASSIFIED DRUG; YOJI PROTEIN; ABC TRANSPORTER; BACTERIOCIN; ESCHERICHIA COLI PROTEIN; MICROCIN; YOJI PROTEIN, E COLI;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM MUTANT; BINDING SITE; CULTURE MEDIUM; DRUG TRANSPORT; ENZYME ACTIVITY; ESCHERICHIA COLI K 12; GENE EXPRESSION; GENE EXPRESSION REGULATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; YOJI GENE; DRUG EFFECT; ESCHERICHIA COLI; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

ESCHERICHIA COLI; ESCHERICHIA COLI K12;

ATP-BINDING CASSETTE TRANSPORTERS; BACTERIOCINS; BASE SEQUENCE; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; LEUCINE; LEUCINE-RESPONSIVE REGULATORY PROTEIN; MOLECULAR SEQUENCE DATA;

EID: 60849134826     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01074-08     Document Type: Article

References (37)

1. Adelman, K., J. Yuzenkova, A. LaPorta, N. Zenkin, J. Lee, J. T. Lis, S. Borukhov, M. D. Wang, and K. Severinov. 2004. Molecular mechanism of transcription inhibition by peptide antibiotic microcin J25. Mol. Cell 14:753-762.
2. Bayro, M. J., J. Mukhopadhyay, G. V. T. Swapna, J. Y. Huang, L.-C. Ma, E. Sineva, P. E. Dawson, G. T. Montelione, and R. H. Ebright. 2003. Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot. J. Am. Chem. Soc. 125:12382-12383.
3. Blond, A., J. Péduzzi, C. Goulard, M. J. Chiuchiolo, M. Barthélémy, Y. Prigent, R. A. Salomón, R. N. Farías, F. Moreno, and S. Rebuffat. 1999. The cyclic structure of microcin J25. a 21-residue peptide antibiotic from Escherichia coli. Eur. J. Biochem. 259:747-755.
4. Calvo, J. M., and R. G. Matthews. 1994. The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli. Microbiol. Rev. 58:466-490.
5. Chen, C., and E. B. Newman. 1998. Comparison of the sensitivities of two Escherichia coli genes to in vivo variation of Lrp concentration. J. Bacteriol. 180:655-659.
6. Chen, S., M. H. Rosner, and J. M. Calvo. 2001. Leucine-regulated self association of leucine-responsive regulatory protein (Lrp) from Escherichia coli. J. Mol. Biol. 312:625-635.
7. Chen, S., Z. Hao, E. Bieniek, and J. M. Calvo. 2001. Modulation of Lrp action in Escherichia coli by leucine: effects on non-specific binding of Lrp to DNA. J. Mol. Biol. 314:1067-1075.
8. Chen, S., and J. M. Calvo. 2002. Leucine-induced dissociation of Escherichia coli Lrp hexadecamers to octamers. J. Mol. Biol. 318:1031-1042.
9. Datsenko, K. A., and B. L. Wanner. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97:6640-6645.
10. De Haan, P. G., W. P. M. Hoekstra, C. Verhoef, and H. S. Felix. 1969. Recombination in Escherichia coli. III. Mapping by the gradient of transmission. Mutat. Res. 8:505-512.
11. Delgado, M. A., J. O. Solbiati, M. J. Chiuchiolo, R. N. Farías, and R. A. Salomón. 1999. Escherichia coli outer membrane protein TolC is involved in the production of the peptide antibiotic microcin J25. J. Bacteriol. 181:1968-1970.
12. Delgado, M. A., M. R. Rintoul, R. N. Farías, and R. A. Salomón. 2001. Escherichia coli RNA polymerase is the target of the cyclopeptide antibiotic microcin J25. J. Bacteriol. 183:4543-4550.
13. Delgado, M. A., P. A. Vincent, R. N. Farías, and R. A. Salomón. 2005. YojI of Escherichia coli functions as a microcin J25 efflux pump. J. Bacteriol. 187:3465-3470.
14. Duquesne, S., D. Destoumieux-Garzón, S. Zirah, C. Goulard, J. Péduzzi, and S. Rebuffat. 2007. Two enzymes catalyze the maturation of a lasso peptide in Escherichia coli. Chem. Biol. 14:793-803.
15. Ellermeier, C. D., A. Janakiraman, and J. M. Slauch. 2002. Construction of targeted single copy lac fusions using λ Red and FLP-mediated site-specific recombination in bacteria. Gene 290:153-161.
16. Haldimann, A., and B. L. Wanner. 2001. Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies in bacteria. J. Bacteriol. 183:6384-6393.
17. Hawley, D. K., and W. R. McClure. 1983. Compilation and analysis of Escherichia coli promoter DNA sequences. Nucleic Acids Res. 11:2237-2255.
18. Landgraf, J. R., J. Wu, and J. M. Calvo. 1996. Effects of nutrition and growth rate on Lrp levels in Escherichia coli. J. Bacteriol. 178:6930-6936.
19. Manoil, C. 1990. Analysis of protein localization by use of gene fusions with complementary properties. J. Bacteriol. 172:1035-1042.
20. Miller, J. H. 1992. A short course in bacterial genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
21. Mukhopadhyay, J., E. Sineva, J. Knight, R. M. Levy, and R. H. Ebright. 2004. Antibacterial peptide microcin J25 inhibits transcription by binding within and obstructing the RNA polymerase secondary channel. Mol. Cell 14:739-751.
22. Newman, E. B., and R. Lin. 1995. Leucine-responsive regulatory protein: a global regulator of gene expression in E. coli. Annu. Rev. Microbiol. 49:747-775.
23. Newman, E. B., R. T. Lin, and R. D'Ari. 1996. The leucine/Lrp regulon, p. 1513-1525. In F. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter. and H. E. Umbarger (ed.). Escherichia coli and Salmonella typhimurium: cellular and molecular biology. ASM Press, Washington, DC.
24. Nickerson, C. A., and E. C. Achberger. 1995. Role of curved DNA in binding of Escherichia coli RNA polymerase to promoters. J. Bacteriol. 177:5756-5761.
25. Nishino, K., and A. Yamaguchi. 2001. Analysis of a complete library of putative drug transporter genes in Escherichia coli. J. Bacteriol. 183:5803-5812.
26. Platko, J. V., and J. M. Calvo. 1993. Mutations affecting the ability of Escherichia coli Lrp to bind DNA, activate transcription, or respond to leucine. J. Bacteriol. 175:1110-1117.
27. Pomares, M. F., P. A. Vincent, R. N. Farías, and R. A. Salomón. 2008. Protective action of ppGpp in microcin J25-sensitive strains. J. Bacteriol. 190:4328-4334.
28. Rex, J. H., B. D. Aronson, and R. L. Somerville. 1991. The tdh and serA operons of Escherichia coli: mutational analysis of the regulatory elements of leucine-responsive genes. J. Bacteriol. 173:5944-5953.
29. Rosengren, K. J., R. J. Clark, N. L. Daly, U. Goransson, A. Jones, and D. J. Craik. 2003. Microcin J25 has a threaded side chain-to-backbone ring structure and not a head-to-tail cyclized backbone. J. Am. Chem. Soc. 125:12464-12474.
30. Salomón, R. A., and R. N. Farías. 1992. Microcin 25, a novel antimicrobial peptide produced by Escherichia coli. J. Bacteriol. 174:7428-7435.
31. Salomón, R. A., and R. N. Farías. 1993. The FhuA protein is involved in microcin 25 uptake J. Bacteriol. 175:7741-7742.
32. Salomón, R. A., and R. N. Farías. 1995. The peptide antibiotic microcin 25 is imported through the TonB pathway and the SbmA protein. J. Bacteriol. 177:3323-3325.
33. Shine, J., and L. Dalgarno. 1974. The 3′-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc. Natl. Acad. Sci. USA 71:1342-1346.
34. Solbiati, J. O., M. Ciaccio, R. N. Farías, and R. A. Salomón. 1996. Genetic analysis of plasmid determinants for microcin 25 production and immunity. J. Bacteriol. 178:3661-3663.
35. Solbiati, J. O., M. Ciaccio, R. N. Farías, J. E. González-Pastor, F. Moreno, and R. A. Salomón. 1999. Sequence analysis of the four plasmid genes required to produce the circular peptide antibiotic microcin J25. J. Bacteriol. 181:2659-2662.
36. Wilson, K. A., M. Kalkum, J. Ottesen, J. Yuzenkova, B. T. Chait, R. Landick, T. Muir, K. Severinov, and S. A. Darst. 2003. Structure of microcin J25. a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. J. Am. Chem. Soc. 125:12475-12483.
37. Yuzenkova, J., M. Delgado, S. Nechaev, D. Savalia, V. Epshtein, I. Artsimovitch, R. A. Mooney, R. Landick, R. N. Farias, R. Salomon, and K. Severinov. 2002. Mutations of bacterial RNA polymerase leading to resistance to microcin J25. J. Biol. Chem. 277:50867-50875.