Leucine-induced dissociation of Escherichia coli Lrp hexadecamers to octamers

Journal of Molecular Biology

Volumn 318, Issue 4, 2002, Pages 1031-1042

  Chen, Shaolin ^a   Calvo, Joseph M ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Escherichia coli; Global regulation; Leucine; Lrp; Oligomerization

Indexed keywords

LEUCINE; PROTEIN; PROTEIN LRP; PROTEIN LRP 1; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; DISSOCIATION; ENERGY; ESCHERICHIA COLI; FLUORESCENCE ANALYSIS; LIGHT SCATTERING; MATHEMATICAL MODEL; OPERON; PRIORITY JOURNAL; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 0036041669     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00187-0     Document Type: Article

References (25)

1. The leucine-responsive regulatory protein (Lrp), a global regulator of metabolism in Escherichia coli
2. The leucine/Lrp regulon
3. The leucine-Lrp regulon in E. coli: A global response in search of a raison d'être
4. The effect of nutrition and growth rate upon Lrp levels in Escherichia coli
5. Characterization of Lrp, an Escherichia coli regulatory protein that mediates a global response to leucine
6. Metabolic regulation of lrp gene expression in Escherichia coli K-12
7. Modulation of Lrp action in Escherichia coli by leucine: Effects on non-specific binding of Lrp to DNA
8. Self-association of leucine-responsive regulatory protein (Lrp) from Escherichia coli
9. Mutations affecting the ability of Escherichia coli Lrp to bind DNA, activate transcription, or respond to leucine
10. Lrp, a global regulatory protein of E. coli, binds cooperatively to multiple sites and activates transcription of ilvIH
11. In vivo footprinting analysis of Lrp binding to the ilvIH promoter region of Escherichia coli
12. Amino acid transport systems in Escherichia coli K-12
13. Role of transport systems in amino acid metabolism: Leucine toxicity and the branched-chain amino acid transport systems
14. Amino acid pool of Escherichia coli during the different phases of growth
15. Measurement of subnanomolar retinoic acid binding affinities for cellular retinoic acid binding proteins by fluorometric titration
16. Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus
17. An Lrp-type transcriptional regulator from Agrobacterium tumefaciens condenses more than 100 nucleotides of DNA into globular nucleoprotein complexes
18. Analysis of growth rate effects on productivity of recombinant Escherichia coli populations using molecular mechanism models
19. Regulation of the gltBDF operon of Escherichia coli: How is a leucine-insensitive operon regulated by the leucine-responsive regulatory protein?
20. The leucine-responsive regulatory protein (Lrp) from Escherichia coli: Stoichiometry and minimal requirements for binding to DNA
21. Wild-type and hexahistidine-tagged derivatives of leucine-responsive regulatory protein from Escherichia coli
22. Calculation of protein extinction coefficients from amino acid sequence data