Heterogenous Expression of the Related MBP70 and MPB83 Proteins Distinguish Various Substrains of Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv

Scandinavian Journal of Immunology

Volumn 43, Issue 4, 1996, Pages 374-380

  Wiker, H G ^a   Nagai, S ^b   Hewinson, R G ^c   Russell, W P ^c   Harboe, M ^a,d  

^a UNIVERSITY OF OSLO   (Norway)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c VETERINARY LABORATORIES AGENCY   (United Kingdom)

^d Inst of Immunology and Rheumatology   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; MONOCLONAL ANTIBODY; MYCOBACTERIUM ANTIGEN;

ARTICLE; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; VIRULENCE;

ANTIBODY SPECIFICITY; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CROSS REACTIONS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; MEMBRANE PROTEINS; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 0029864754     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1996.d01-61.x     Document Type: Article

References (27)

1. Harboe M, Nagai S. MPB70, a unique antigen of Mycobacterium bovis BCG. Am Rev Respir Dis 1994;129:444-52.
2. Miura K, Nagai S, Kinomoto M, Haga S, Tokunaga T. Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70. Infect Immun 1983;39:540-5.
3. Matsuo T, Matsumoto S, Ohara N, Kitaura H, Mizuno A, Yamada T. Differential transcription of the MPB70 genes in two major groups of Mycobacterium bovis BCG substrains. Microbiol 1995;141:1601-7.
4. Harboe M, Wiker HG, Duncan JR et al. Protein G-based enzyme-linked immunosorbent assay for anti-MPB70 antibodies in bovine tuberculosis. J Clin Microbiol 1990;28:913-21.
5. Fifis T, Costopoulos C, Radford AJ, Bacic A, Wood PR. Purification and characterization of major antigens from a Mycobacterium bovis culture filtrate. Infect Immun 1991; 59:800-7.
6. Fifis T, Costopoulos C, Corner LA, Wood PR. Serological reactivity to Mycobacterium bovis protein antigens in cattle. Vet Microbiol 1992;30:343-54.
7. Wood PR, Corner LA, Rothel JS et al. A field evaluation of serological and cellular diagnostic tests for bovine tuberculosis. Vet Microbiol 1992;31:71-9.
8. Fifis T, Corner LA, Rothel JS, Wood PR. Cellular and humoral immune responses to purified Mycobacterium bovis antigens. Scand J Immunol 1994;39:267-74.
9. Pollock JM, Douglas AJ, Mackie DP, Neill SD. Identification of bovine T cell epitopes for three Mycobacterium bovis antigens: MPB70, 19 000 MW and MPB57. Immunology 1994;82:9-15.
10. Hasløv K, Andersen ÅB, Bentzon MW. Biological activity in sensitized guinea pigs of MPB70, a protein specific for some strains of Mycobacterium bovis BCG. Scand J Immunol 1987;26:445-54.
11. Harboe M, Wiker HG, Lachmann P. Carrier effect of Concanavalin A-reactive and -non-reactive material in tuberculin PPD. Scand J Immunol 1990;32:263-71.
12. Ulstrup JC, Jeansson S, Wiker HG, Harboe M. Relationship of secretion pattern and MPB70 homology with osteoblastspecific factor 2 to osteitis following Mycobacterium bovis BCG vaccination. Infect Immun 1995;63:672-5.
13. Takeshita S, Kikuno R, Tezuka K, Amann E. Osteoblastspecific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I Biochem J 1993;294:271-8.
14. Harboe M, Nagai S, Wiker HG, Sletten K, Haga S. Homology between the MPB70 and MPB83 proteins of Mycobacterium bovis BCG. Scand J Immunol 1995;42:46-51.
15. Nagai S, Matsumoto J, Nagasuga T. Specific skin-reactive protein from culture filtrate of Mycobacterium bovis BCG. Infect Immun. 1981;31:1152-60.
16. Morris JA, Thorns CJ, Wooley J. The identification of antigenic determinants on Mycobacterium bovis using monoclonal antibodies. J Gen Microbiol 1985;131:1825-31.
17. Hewinson RG, Russell WP. Processing and secretion by Escherichia coli of a recombinant form of the immunogenic protein MPB70 of Mycobacterium bovis. J Gen Microbiol 1993; 139:1253-9.
18. Goodger J, Nolan A, Russell WP et al. Serodiagnosis of Mycobacterium bovis infection in badgers: development of an indirect ELISA using 25kDa antigen. Veterinary Record 1994;135:82-5.
19. Goodger J, Russell WP, Nolan A, Newell DG. Production and characterization of a monoclonal badger anti-immunoglobulin G and its use in defining the specificity of Mycobacterium bovis infection in badgers by western blot. Veterinary Immunol Immunopathol 1994;40:243-52.
20. Wiker HG, Harboe M, Nagai S, Bennedsen J. Quantitative and qualitative studies on the major extracellular antigen of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis BCG. Am Rev Respir Dis 1990;141:830-8.
21. Abou-Zeid C, Harboe M, Rook GAW. Characterization of the secreted antigens of Mycobacterium bovis BCG: comparison of the 46-kilodalton dimeric protein with proteins MPB64 and MPB70. Infect Immun 1987;55:3213-14.
22. Harboe M, Nagai S, Patarroyo ME, Torres ML, Ramirez C, Cruz N. Properties of proteins MPB64, MPB70, and MPB80 of Mycobacterium bovis BCG. Infect Immun 1986;52:293-302.
23. Li H, Ulstrup JC, Jonassen TØ, Melby K, Nagai S, Harboe M. Evidence for absence of the MPB64 gene in some substrains of Mycobacterium bovis BCG. Infect Immun 1993;61:1730-4.
24. Oettinger T, Andersen AB. Cloning and B cell-epitope mapping of MPT64 from Mycobacterium tuberculosis H37Rv. Infect Immun 1994;62:2058-64.
25. Young DB, Kaufmann SHE, Hermans PWM, Thole JER. Mycobacterial protein antigens: a compilation. Mol Microbiol 1992; 6:133-45.
26. Wiker HG, Nagai S, Harboe H, Ljungqvist L. A family of cross-reactive proteins secreted by Mycobacterium tuberculosis. Scand J Immunol 1992;36:307-19.
27. Fifis T, Plackett P, Corner LA, Wood PR. Purification of a major Mycobacterium bavis antigen for the diagnosis of bovine tuberculosis. Scand J Immunol 1989;29:91-101.