Quinine-dependent, platelet-reactive monoclonals mimic antibodies found in patients with quinine-induced immune thrombocytopenia

Blood

Volumn 113, Issue 5, 2009, Pages 1105-1111

  Bougie, Daniel W ^a   Birenbaum, Jessica ^a   Rasmussen, Mark ^a   Poncz, Mortimer ^b   Aster, Richard H ^a,c  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIB; GLYCOPROTEIN IIIA; HAPTEN; MONOCLONAL ANTIBODY; QUININE; ANALGESIC AGENT; AUTOANTIBODY;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIGEN BINDING; ARTICLE; COVALENT BOND; DRUG INDUCED DISEASE; DRUG INDUCED IMMUNE THROMBOCYTOPENIA; DRUG TARGETING; IMMUNE RESPONSE; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTOPENIA; ANIMAL; CHEMICALLY INDUCED DISORDER; CHO CELL; CRICETULUS; HAMSTER; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOLOGY; PROTEIN TERTIARY STRUCTURE;

ANALGESICS, NON-NARCOTIC; ANIMALS; ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; BLOOD PLATELETS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MICE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN STRUCTURE, TERTIARY; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; QUININE;

EID: 60849113420     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-09-177279     Document Type: Article

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