Heterotypic interactions in the preservation of morphology and functionality of porcine hepatocytes by bone marrow mesenchymal stem cells in vitro

Journal of Cellular Physiology

Volumn 219, Issue 1, 2009, Pages 100-108

  Gu, Jinyang ^a,b,c   Shi, Xiaolei ^b,c   Zhang, Yue ^a,b,c   Ding, Yitao ^a,b,c  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c Jiangsu Province's Key Medical Center for Hepatobiliary Disease   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 5; CYTOCHROME P450 3A1; FIBRONECTIN; LAMININ; UREA; ALBUMINOID; SCLEROPROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DEATH; CELL FUNCTION; CELL INTERACTION; CELL METABOLISM; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LIVER CELL; MESENCHYMAL STEM CELL; NONHUMAN; PRESERVATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SPHEROID CELL; SWINE; ANIMAL; BONE MARROW CELL; CELL CULTURE; CELL SHAPE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; GENETICS; HUMAN; METABOLISM; MULTICELLULAR SPHEROID;

SUS;

ALBUMINS; ANIMALS; BONE MARROW CELLS; CELL SHAPE; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HEPATOCYTES; HUMANS; MESENCHYMAL STEM CELLS; RNA, SMALL INTERFERING; SPHEROIDS, CELLULAR; SWINE;

EID: 60849092547     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21651     Document Type: Article

References (36)

1. BerthiaumeF, Moghe PV, Toner M, Yarmush ML. 1996. Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: Hepatocytes cultured in a sandwich configuration. FASEB J 10:1471-1484.
2. Bhatia SN, Balis UJ, Yarmush ML, Toner M. 1999. Effect of cell-cell interactions in preservation of cellular phenotype: Co-cultivation of hepatocytes and non-parenchymal cells. FASEB J 13:1883-1900.
3. Bissell DM, Guzelian PS. 1980. Phenotypic stability of adult rat hepatocytes in primary monolayer culture. Ann NY Acad Sci 349:85-98.
4. Burugapalli K, Thapasimuttu A, Chan JC, Yao L, Brody S, Kelly JL, Pandit A. 2007. Scaffold with a natural mesh-like architecture: Isolation, structural, and in vitro characterization. Biomacromolecules 8:928-936.
5. Chan C, Berthiaume F, Nath BD, Tilles AW, Toner M, Yarmush ML. 2004. Hepatic tissue engineering for adjunct and temporary liver support: Critical technologies. Liver Transpl 10:1331-1342.
6. Demetriou AA, Brown RS, Jr., Busuttil RW, Fair J, McGuire BM, Rosenthal P, Am Esch JS II, Lerut J, Nyberg SL, Salizzoni M, Fagan EA, de Hemptinne B, Broelsch CE, Muraca M, Salmeron JM, Rabkin JM, Metselaar HJ, Pratt D, De La Mata M, McChesney LP, Everson GT, Lavin PT, Stevens AC, Pitkin Z, Solomon BA. 2004. Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure. Ann Surg 239:660-667.
7. Di Campli C, Nestola M, Piscaglia AC, Santoliquido A, Gasbarrini G, Pola P, Gasbarrini A. 2003. Cell-based therapy for liver diseases. Eur Rev Med Pharmacol Sci 7:41-44.
8. Elaut G, Henkens T, Papeleu P, Snykers S, Vinken M, Vanhaecke T, Rogiers V. 2006. Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. Curr Drug Metab 7:629-660.
9. Guo KT, SchAfer R, Paul A, Gerber A, Ziemer G, Wendel HP. 2006. A new technique for the isolation and surface immobilization of mesenchymal stem cells from whole bone marrow using high-specific DNA aptamers. Stem Cells 24:2220-2231.
10. Ijima H, Murakami S, Matsuo T, Takei T, Ono T, Kawakami K. 2005. Enhancement of liver- specific functions of primary rat hepatocytes co-cultured with bone marrow cells on tissue culture-treated polystyrene surfaces. J Artif Organs 8:104-109.
11. Isoda K, Kojima M, Takeda M, Higashiyama S, Kawase M, Yagi K. 2004. Maintenance of hepatocyte functions by coculture with bone marrow stromal cells. J Biosci Bioeng 97:343-346.
12. Khashab M, Tector AJ, Kwo PY. 2007. Epidemiology of acute liver failure. Curr Gastroenterol Rep 9:66-73.
13. Lee KD, Kuo TK, Whang-Peng J, Chung YF, Lin CT, Chou SH, Chen JR, Chen YP, Lee OK. 2004. In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology 40:1275-1284.
14. Li J, Chen X, Dong X, Xu Z, Jiang H, Sun X. 2006. Specific COX-2 inhibitor, meloxicam, suppresses proliferation and induces apoptosis in human HepG2 hepatocellular carcinoma cells. J Gastroenterol Hepatol 21:1814-1820.
15. Lysy PA, Campard D, Smets F, Malaise J, Mourad M, Najimi M, Sokal EM. 2008. Persistence of a chimerical phenotype after hepatocyte differentiation of human bone marrow mesenchymal stem cells. Cell Prolif 41:36-58.
16. Mitaka T. 1998. The current status of primary hepatocyte culture. Int J Exp Pathol 79:393-409.
17. Mizuguchi T, Palm K, Hui T, Aoki T, Mochizuki Y, Mitaka T, Demetriou AA, Rozga J. 2002. Effects of bone marrow stromal cells on the structural and functionalpolarity of primary rat hepatocytes. In Vitro Cell Dev Biol Anim 38:62-65.
18. Nishikawa M, Kojima N, Komori K, Yamamoto T, Fujii T, Sakai Y. 2008. Enhanced maintenance and functions of rat hepatocytes induced by combination of on-site oxygenation and co-culture with fibroblasts. J Biotechnol 133:253-260.
19. Papeleu P, Vanhaecke T, Henkens T, Elaut G, Vinken M, Snykers S, Rogiers V. 2006. Isolation of rat hepatocytes. Methods Mol Biol 320:229-237.
20. Patel SA, Sherman L, Munoz J, RameshwarP. 2008. Immunologicalproperties of mesenchymal stem cells and clinical implications. Arch Immunol Ther Exp 56:1-8.
21. Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N, Boggs SS, Greenberger JS, Goff JP. 1999. Bone marrow as a potential source of hepatic oval cells. Science 284:1168-1170.
22. Poyck PP, Hoekstra R, van Wijk AC, Attanasio C, Calise F, Chamuleau RA, van Gulik TM. 2007. Functional and morphological comparison of three primary liver cell types cultured in the AMC bioartificial liver. Liver Transpl 13:589-598.
23. Price JA, Caldwell J, Hewitt NJ. 2006. The effect of EGF and the comitogen, norepinephrine, on the proliferative responses of fresh and cryopreserved rat and mouse hepatocytes. Cryobiology 53:182-193.
24. Seglen PO. 1976. Preparation of isolated rat liver cells. Methods Cell Biol 13:29-83.
25. Seo SJ, Choi YJ, Akaike T, Higuchi A, Cho CS. 2006a. Alginate/ galactosylated chitosan/heparin scaffold as a new synthetic extracellular matrix for hepatocytes. Tissue Eng 12:33-44.
26. Seo SJ, Kim IY, Choi YJ, Akaike T, Cho CS. 2006b. Enhanced liver functions of hepatocytes cocultured with NIH 3T3 in the alginate/galactosylated chitosan scaffold. Biomaterials 27:1487-1495.
27. Stadlbauer V, Davies NA, Sen S, Jalan R. 2008. Artificial liver support systems in the management of complications of cirrhosis. Semin Liver Dis 28:96-109.
28. Stadlbauer V, Jalan R. 2007. Acute liver failure: Liver support therapies. Curr Opin Crit Care 13:215-221.
29. Sympson CJ, Talhouk RS, Alexander CM, Chin JR, Clift SM, Bissell MJ, Werb Z. 1994. Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression. J Cell Biol 125:681-693.
30. Takai K, Hara J, Matsumoto K, Hosoi G, Osugi Y, Tawa A, Okada S, Nakamura T. 1997. Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis. Blood 89:1560-1565.
31. Theise ND, Badve S, Saxena R, Henegariu O, Sell S, Crawford JM, Krause DS. 2000. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 31:235-240.
32. Thomas RJ, Bhandari R, Barrett DA, Bennett AJ, Fry JR, Powe D, Thomson BJ, Shakesheff KM. 2005. The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro. Cells Tissues Organs 181:67-79.
33. Tsuda Y, Kikuchi A, Yamato M, Chen G, Okano T. 2006. Heterotypic cell interactions on a dually patterned surface. Biochem Biophys Res Commun 348:937-944.
34. Ueno H, Sakita-Ishikawa M, MorikawaY, NakanoT, KitamuraT, Saito M. 2003. A stromal cell- derived membrane protein that supports hematopoietic stem cells. Nat Immunol 4:457-463.
35. Verdonk RC, van den Berg AP, Slooff MJ, Porte RJ, Haagsma EB. 2007. Liver transplantation: An update. Neth J Med 65:372-380.
36. Zinchenko YS, Coger RN. 2005. Engineering micropatterned surfaces for the coculture of hepatocytes and Kupffer cells. J Biomed Mater Res A 75:242-248.