-
1
-
-
38349186895
-
Replication stress induces tumor-like microdeletions in FHIT/FRA3B
-
Durkin SG, Ragland RL, Arlt MF, et al. Replication stress induces tumor-like microdeletions in FHIT/FRA3B. Proc Natl Acad Sci USA. 2008;105:246-251.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 246-251
-
-
Durkin, S.G.1
Ragland, R.L.2
Arlt, M.F.3
-
2
-
-
44349119351
-
Oncogene- induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study
-
Tsantoulis PK, Kotsinas A, Sfikakis PP, et al. Oncogene- induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study. Oncogene. 2008;27:3256-3264.
-
(2008)
Oncogene
, vol.27
, pp. 3256-3264
-
-
Tsantoulis, P.K.1
Kotsinas, A.2
Sfikakis, P.P.3
-
3
-
-
27644582835
-
-
Thavathiru E, Ludes-Meyers JH, MacLeod MC, Aldaz CM. Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR. Mol Carcinog. 2005;44:174-182.
-
Thavathiru E, Ludes-Meyers JH, MacLeod MC, Aldaz CM. Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR. Mol Carcinog. 2005;44:174-182.
-
-
-
-
4
-
-
1842581808
-
The fragile genes, FHIT and WWOX, are coordinately inactivated in invasive breast cancer: Correlations with clinical features
-
Guler G, Uner A, Guler N, et al. The fragile genes, FHIT and WWOX, are coordinately inactivated in invasive breast cancer: correlations with clinical features. Cancer. 2004;100: 1605-1614.
-
(2004)
Cancer
, vol.100
, pp. 1605-1614
-
-
Guler, G.1
Uner, A.2
Guler, N.3
-
5
-
-
23244433750
-
Concordant loss of fragile genes, Fhit and Wwox, in breast cancer development
-
Guler G, Uner A, Guler N, et al. Concordant loss of fragile genes, Fhit and Wwox, in breast cancer development. Pathol Int. 2005;55:471-478.
-
(2005)
Pathol Int
, vol.55
, pp. 471-478
-
-
Guler, G.1
Uner, A.2
Guler, N.3
-
6
-
-
35948973956
-
Wwox and Ap2γ expression levels predict tamoxifen response
-
Guler G, Iliopoulos D, Guler N, et al. Wwox and Ap2γ expression levels predict tamoxifen response. Clin Cancer Res. 2007;13:6115-6121.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6115-6121
-
-
Guler, G.1
Iliopoulos, D.2
Guler, N.3
-
7
-
-
13844281272
-
Frequent loss of WWOX expression in breast cancer: Correlation with estrogen receptor status
-
Nunez MI, Ludes-Meyers J, Abba MC, et al. Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status. Breast Cancer Res Treat. 2005;89:99-105.
-
(2005)
Breast Cancer Res Treat
, vol.89
, pp. 99-105
-
-
Nunez, M.I.1
Ludes-Meyers, J.2
Abba, M.C.3
-
8
-
-
33645838382
-
Chromosomal fragile sites FRA3B and FRA16D show correlated expression and association with failure of apoptosis in lymphocytes from patients with thyroid cancer
-
Sbrana I, Veroni F, Nieri M, et al. Chromosomal fragile sites FRA3B and FRA16D show correlated expression and association with failure of apoptosis in lymphocytes from patients with thyroid cancer. Genes Chromosomes Cancer. 2006;45:429-436.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 429-436
-
-
Sbrana, I.1
Veroni, F.2
Nieri, M.3
-
9
-
-
0344874589
-
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies
-
Ishii H, Vecchione A, Furukawa Y, et al. Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies. Mol Cancer Res. 2003;1:940-947.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 940-947
-
-
Ishii, H.1
Vecchione, A.2
Furukawa, Y.3
-
10
-
-
8544283814
-
Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor
-
Aqeilan RI, Palamarchuk A, Weigel RJ, et al. Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor. Cancer Res. 2004;64:8256-8261.
-
(2004)
Cancer Res
, vol.64
, pp. 8256-8261
-
-
Aqeilan, R.I.1
Palamarchuk, A.2
Weigel, R.J.3
-
11
-
-
23044492008
-
WW domain- containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function
-
Aqeilan RI, Donati V, Palamarchuk A, et al. WW domain- containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function. Cancer Res. 2005;65:6764-6772.
-
(2005)
Cancer Res
, vol.65
, pp. 6764-6772
-
-
Aqeilan, R.I.1
Donati, V.2
Palamarchuk, A.3
-
12
-
-
0029910361
-
A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma
-
Bosher JM, Totty NF, Hsuan JJ, et al. A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma. Oncogene. 1996;17:1701-1707.
-
(1996)
Oncogene
, vol.17
, pp. 1701-1707
-
-
Bosher, J.M.1
Totty, N.F.2
Hsuan, J.J.3
-
13
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
14
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA. 2001;98:10869-10874.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
15
-
-
37248999372
-
Triple negative tumours: A critical review
-
Reis-Filho JS, Tutt ANJ. Triple negative tumours: a critical review. Histopathology. 2008;52:108-118.
-
(2008)
Histopathology
, vol.52
, pp. 108-118
-
-
Reis-Filho, J.S.1
Tutt, A.N.J.2
-
16
-
-
33750976943
-
Deconstructing the molecular portrait of basal-like breast cancer
-
Yehiely F, Moyano JV, Evans RE, et al. Deconstructing the molecular portrait of basal-like breast cancer. Trends Mol Med. 2006;12:537-544.
-
(2006)
Trends Mol Med
, vol.12
, pp. 537-544
-
-
Yehiely, F.1
Moyano, J.V.2
Evans, R.E.3
-
17
-
-
33847136743
-
Triple-negative breast cancer: Therapeutic options
-
Cleator S, Heller W, Coombs RC. Triple-negative breast cancer: therapeutic options. Lancet Oncol. 2007;8:235-244.
-
(2007)
Lancet Oncol
, vol.8
, pp. 235-244
-
-
Cleator, S.1
Heller, W.2
Coombs, R.C.3
-
18
-
-
33847022042
-
BRCA1 dysfunction in sporadic basal-like breast cancer
-
Turner NC, Reis-Filho JS, Russell AM, et al. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene. 2006;26:2126-2132.
-
(2006)
Oncogene
, vol.26
, pp. 2126-2132
-
-
Turner, N.C.1
Reis-Filho, J.S.2
Russell, A.M.3
-
19
-
-
33749022506
-
Basal-like breast cancer and the BRCA1 phenotype
-
Turner NC, Reis-Filho JS. Basal-like breast cancer and the BRCA1 phenotype. Oncogene. 2006;25:5846-5853.
-
(2006)
Oncogene
, vol.25
, pp. 5846-5853
-
-
Turner, N.C.1
Reis-Filho, J.S.2
-
20
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
Nielson TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004;10:5367-5374.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5367-5374
-
-
Nielson, T.O.1
Hsu, F.D.2
Jensen, K.3
-
21
-
-
40949121882
-
Basal-like breast cancer defined by 5 biomarkers has superior prognostic value than triple-negative phenotype
-
Cheang MC, Voduc D, Bajdik C, et al. Basal-like breast cancer defined by 5 biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res. 2008;14:1368-1376.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1368-1376
-
-
Cheang, M.C.1
Voduc, D.2
Bajdik, C.3
-
22
-
-
12944309911
-
Muir-Torre-like syndrome in Fhit-deficient mice
-
Fong LY, Fidanza V, Zanesi N, et al. Muir-Torre-like syndrome in Fhit-deficient mice. Proc Natl Acad Sci USA. 2000;97:4742-4747.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4742-4747
-
-
Fong, L.Y.1
Fidanza, V.2
Zanesi, N.3
-
24
-
-
34247273473
-
Targeted deletion of Wwox reveals a tumor suppressor function
-
Aqeilan RI, Trapasso F, Hussain S, et al. Targeted deletion of Wwox reveals a tumor suppressor function. Proc Natl Acad Sci USA. 2007;104:3949-3954.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3949-3954
-
-
Aqeilan, R.I.1
Trapasso, F.2
Hussain, S.3
-
25
-
-
0037099669
-
The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers
-
Turner BC, Ottey M, Zimonjic DB, et al. The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers. Cancer Res. 2002;62:4054-4060.
-
(2002)
Cancer Res
, vol.62
, pp. 4054-4060
-
-
Turner, B.C.1
Ottey, M.2
Zimonjic, D.B.3
-
26
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature. 2005;434:907-913.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
-
27
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature. 2005;434:864-870.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
-
28
-
-
36949005417
-
DNA damage signalling guards against activated oncogenes and tumour progression
-
Bartek J, Bartkova J, Lukas J. DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene. 2007;26:7773-7779.
-
(2007)
Oncogene
, vol.26
, pp. 7773-7779
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
29
-
-
33845796072
-
Fhit modulates the DNA damage checkpoint response
-
Ishii H, Mimori K, Inoue H, et al. Fhit modulates the DNA damage checkpoint response. Cancer Res. 2006;66:11287-11292.
-
(2006)
Cancer Res
, vol.66
, pp. 11287-11292
-
-
Ishii, H.1
Mimori, K.2
Inoue, H.3
-
30
-
-
34248141602
-
A Fhit-ing role in the DNA damage checkpoint response
-
Ishii H, Wang Y, Huebner K. A Fhit-ing role in the DNA damage checkpoint response. Cell Cycle. 2007;6:1044-1048.
-
(2007)
Cell Cycle
, vol.6
, pp. 1044-1048
-
-
Ishii, H.1
Wang, Y.2
Huebner, K.3
-
31
-
-
50249162487
-
Molecular parameters of genome instability: Roles of fragile genes at common fragile sites
-
Pichiorri F, Ishii H, Okumura H, et al. Molecular parameters of genome instability: roles of fragile genes at common fragile sites. J Cell Biochem. 2008;104:1525-1533.
-
(2008)
J Cell Biochem
, vol.104
, pp. 1525-1533
-
-
Pichiorri, F.1
Ishii, H.2
Okumura, H.3
-
32
-
-
56549131207
-
Deletions of BRCA1/2 and p53 R248W gain-of-function mutation suggest impaired homologous recombination repair in fragile histidine triad-negative sebaceous gland carcinomas
-
Becker K, Goldberg M, Helmbold P, et al. Deletions of BRCA1/2 and p53 R248W gain-of-function mutation suggest impaired homologous recombination repair in fragile histidine triad-negative sebaceous gland carcinomas. Br J Dermatol. 2008;159:1282-1289.
-
(2008)
Br J Dermatol
, vol.159
, pp. 1282-1289
-
-
Becker, K.1
Goldberg, M.2
Helmbold, P.3
-
33
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature. 2005;434:913-917.
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
-
34
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe R, Lord CJ, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 2005;434:917-921.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, R.2
Lord, C.J.3
-
35
-
-
36949012288
-
Targeted cancer therapies based on the inhibition of DNA strand break repair
-
O'Connor MJ, Martin NMB, Smith GCM. Targeted cancer therapies based on the inhibition of DNA strand break repair. Oncogene. 2007;26:7816-7824.
-
(2007)
Oncogene
, vol.26
, pp. 7816-7824
-
-
O'Connor, M.J.1
Martin, N.M.B.2
Smith, G.C.M.3
-
36
-
-
34547109117
-
The E2F- regulated gene Chk1 is highly expressed in triple-negative estrogen receptor-/progesterone receptor-/Her1 -breast carcinomas
-
Verlinden L, Vandem Bempt I, Eelen G, et al. The E2F- regulated gene Chk1 is highly expressed in triple-negative estrogen receptor-/progesterone receptor-/Her1 -breast carcinomas. Cancer Res. 2007;67:6574-6581.
-
(2007)
Cancer Res
, vol.67
, pp. 6574-6581
-
-
Verlinden, L.1
Vandem Bempt, I.2
Eelen, G.3
-
37
-
-
30144438249
-
Roles of FHIT and WWOX fragile genes in cancer
-
Iliopoulos D, Guler G, Han SY, et al. Roles of FHIT and WWOX fragile genes in cancer. Cancer Lett. 2006;232:27-36.
-
(2006)
Cancer Lett
, vol.232
, pp. 27-36
-
-
Iliopoulos, D.1
Guler, G.2
Han, S.Y.3
-
39
-
-
45549109220
-
FHIT-deficient hematopoietic stem cells survive hydroquinone treatment long-term, carrying precancerous alterations
-
Ishii H, Mimori K, Ishikawa K, et al. FHIT-deficient hematopoietic stem cells survive hydroquinone treatment long-term, carrying precancerous alterations. Cancer Res. 2008;68:3662-3670.
-
(2008)
Cancer Res
, vol.68
, pp. 3662-3670
-
-
Ishii, H.1
Mimori, K.2
Ishikawa, K.3
|