-
1
-
-
0035262598
-
Targeting tumour vasculature: The development of combretastatin A4
-
Griggs J, Metcalfe JC and Hesketh R: Targeting tumour vasculature: the development of combretastatin A4. Lancet Oncol 2: 82-87, 2001.
-
(2001)
Lancet Oncol
, vol.2
, pp. 82-87
-
-
Griggs, J.1
Metcalfe, J.C.2
Hesketh, R.3
-
3
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
Arap W, Pasqualini R and Ruoslahti E: Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279: 377-380, 1998.
-
(1998)
Science
, vol.279
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
4
-
-
0036891466
-
Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy
-
Ran S and Thorpe PE: Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy. Int J Radiat Oncol Biol Phys 54: 1479-1484, 2002.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1479-1484
-
-
Ran, S.1
Thorpe, P.E.2
-
5
-
-
2242469358
-
Exploiting the differential production of angiogenic factors within the tumor microenvironment in the design of a novel vascular-targeted gene therapy-based approach to the treatment of cancer
-
Carpenito C, Davis PD, Dougherty ST and Dougherty GJ: Exploiting the differential production of angiogenic factors within the tumor microenvironment in the design of a novel vascular-targeted gene therapy-based approach to the treatment of cancer. Int J Radiat Oncol Biol Phys 54: 1473-1478, 2002.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1473-1478
-
-
Carpenito, C.1
Davis, P.D.2
Dougherty, S.T.3
Dougherty, G.J.4
-
6
-
-
0036891050
-
DMXAA: An antivascular agent with multiple host responses
-
Baguley BC and Ching LM: DMXAA: an antivascular agent with multiple host responses. Int J Radiat Oncol Biol Phys 54: 1503-1511, 2002.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1503-1511
-
-
Baguley, B.C.1
Ching, L.M.2
-
7
-
-
0030875686
-
Immunomodulatory action of xanthenone anticancer agents
-
Baguley BC and Ching L-M: Immunomodulatory action of xanthenone anticancer agents. Biodrugs 8: 119-127, 1997.
-
(1997)
Biodrugs
, vol.8
, pp. 119-127
-
-
Baguley, B.C.1
Ching, L.-M.2
-
8
-
-
0030002174
-
Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents
-
Pedley RB, Boden JA, Boden R, Boxer GM, Flynn AA, Keep PA and Begent RH: Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents. Cancer Res 56: 3293-3300, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 3293-3300
-
-
Pedley, R.B.1
Boden, J.A.2
Boden, R.3
Boxer, G.M.4
Flynn, A.A.5
Keep, P.A.6
Begent, R.H.7
-
9
-
-
0028124643
-
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents
-
Zwi LJ, Baguley BC, Gavin JB and Wilson WR: Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents. Oncol Res 6: 79-85, 1994.
-
(1994)
Oncol Res
, vol.6
, pp. 79-85
-
-
Zwi, L.J.1
Baguley, B.C.2
Gavin, J.B.3
Wilson, W.R.4
-
10
-
-
0031858141
-
Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs
-
Lash CJ, Li AE, Rutland M, Baguley BC, Zwi LJ and Wilson WR: Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs. Br J Cancer 78: 439-445, 1998.
-
(1998)
Br J Cancer
, vol.78
, pp. 439-445
-
-
Lash, C.J.1
Li, A.E.2
Rutland, M.3
Baguley, B.C.4
Zwi, L.J.5
Wilson, W.R.6
-
11
-
-
0026089375
-
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice
-
Thomsen LL, Ching LM, Zhuang L, Gavin JB and Baguley BC: Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice. Cancer Res 51: 77-81, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 77-81
-
-
Thomsen, L.L.1
Ching, L.M.2
Zhuang, L.3
Gavin, J.B.4
Baguley, B.C.5
-
12
-
-
0034812637
-
The antitumour agent 5,6-dimethylxanthenone-4-acetic acid acts in vitro on human mononuclear cells as a co-stimulator with other inducers of tumour necrosis factor
-
Philpott M, Ching LM and Baguley BC: The antitumour agent 5,6-dimethylxanthenone-4-acetic acid acts in vitro on human mononuclear cells as a co-stimulator with other inducers of tumour necrosis factor. Eur J Cancer 37: 1930-1937, 2001.
-
(2001)
Eur J Cancer
, vol.37
, pp. 1930-1937
-
-
Philpott, M.1
Ching, L.M.2
Baguley, B.C.3
-
13
-
-
0029894709
-
Synthesis and antitumor activity of some analogues of flavone acetic acid
-
Valenti P, Fabbri G, Rampa A, Bisi A, Gobbi S, Da Re P, Carrara M, Sgevano A and Cima L: Synthesis and antitumor activity of some analogues of flavone acetic acid. Anticancer Drug Des 11: 243-252, 1996.
-
(1996)
Anticancer Drug Des
, vol.11
, pp. 243-252
-
-
Valenti, P.1
Fabbri, G.2
Rampa, A.3
Bisi, A.4
Gobbi, S.5
Da Re, P.6
Carrara, M.7
Sgevano, A.8
Cima, L.9
-
14
-
-
0032427301
-
Synthesis of flavone-2′-carboxylic acid analogues as potential antitumor agents
-
Valenti P, Bisi A, Rampa A, Gobbi S, Belluti F, Da Re P, Cima L and Carrara M: Synthesis of flavone-2′-carboxylic acid analogues as potential antitumor agents. Anticancer Drug Des 13: 881-892, 1998.
-
(1998)
Anticancer Drug Des
, vol.13
, pp. 881-892
-
-
Valenti, P.1
Bisi, A.2
Rampa, A.3
Gobbi, S.4
Belluti, F.5
Da Re, P.6
Cima, L.7
Carrara, M.8
-
15
-
-
0034089324
-
Synthesis and biological activity of some rigid analogues of flavone-8-acetic acid
-
Valenti P, Bisi A, Rampa A, Belluti F, Gobbi S, Zampiron A and Carrara M: Synthesis and biological activity of some rigid analogues of flavone-8-acetic acid. Bioorg Med Chem 8: 239-246, 2000.
-
(2000)
Bioorg Med Chem
, vol.8
, pp. 239-246
-
-
Valenti, P.1
Bisi, A.2
Rampa, A.3
Belluti, F.4
Gobbi, S.5
Zampiron, A.6
Carrara, M.7
-
16
-
-
0037168054
-
Synthesis and antitumor activity of new derivatives of xanthen-9-one-4-acetic acid
-
Gobbi S, Rampa A, Bisi A, Belluti F, Valenti P, Caputo A, Zampiron A and Carrara M: Synthesis and antitumor activity of new derivatives of xanthen-9-one-4-acetic acid. J Med Chem 45: 4931-4939, 2002.
-
(2002)
J Med Chem
, vol.45
, pp. 4931-4939
-
-
Gobbi, S.1
Rampa, A.2
Bisi, A.3
Belluti, F.4
Valenti, P.5
Caputo, A.6
Zampiron, A.7
Carrara, M.8
-
17
-
-
0042231993
-
Synthesis and biological evaluation of 3-alkoxy analogues of flavone-8-acetic acid
-
Gobbi S, Rampa A, Bisi A, Belluti F, Piazzi L, Valenti P, Caputo A, Zampiron A and Carrara M: Synthesis and biological evaluation of 3-alkoxy analogues of flavone-8-acetic acid. J Med Chem 46: 3662-3669, 2003.
-
(2003)
J Med Chem
, vol.46
, pp. 3662-3669
-
-
Gobbi, S.1
Rampa, A.2
Bisi, A.3
Belluti, F.4
Piazzi, L.5
Valenti, P.6
Caputo, A.7
Zampiron, A.8
Carrara, M.9
-
18
-
-
33646175026
-
New derivatives of xanthenone-4-acetic acid: Synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells
-
Gobbi S, Belluti F, Bisi A, Piazzi L, Rampa A, Zampiron A, Barbera M, Caputo A and Carrara M: New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells. Bioorg Med Chem 14: 4101-4109, 2006.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 4101-4109
-
-
Gobbi, S.1
Belluti, F.2
Bisi, A.3
Piazzi, L.4
Rampa, A.5
Zampiron, A.6
Barbera, M.7
Caputo, A.8
Carrara, M.9
-
19
-
-
20244379287
-
Mono- or difluorinated analogues of flavone-8-acetic acid: Synthesis and in vitro biological activity
-
Carrara M, Zampiron A, Barbera M, Caputo A, Bisi A, Gobbi S, Belluti F, Piazzi L, Rampa A and Valenti P: Mono- or difluorinated analogues of flavone-8-acetic acid: synthesis and in vitro biological activity. Anticancer Res 25: 1179-1185, 2005.
-
(2005)
Anticancer Res
, vol.25
, pp. 1179-1185
-
-
Carrara, M.1
Zampiron, A.2
Barbera, M.3
Caputo, A.4
Bisi, A.5
Gobbi, S.6
Belluti, F.7
Piazzi, L.8
Rampa, A.9
Valenti, P.10
-
20
-
-
0032853898
-
Key factors in the acquisition of contrast kinetic data for oncology
-
Evelhoch JL: Key factors in the acquisition of contrast kinetic data for oncology. J Magn Reson Imaging 10: 254-259, 1999.
-
(1999)
J Magn Reson Imaging
, vol.10
, pp. 254-259
-
-
Evelhoch, J.L.1
-
21
-
-
33750539995
-
Vascular disrupting agents
-
Pilat MJ and Lorusso PM: Vascular disrupting agents. J Cell Biochem 99: 1021-1039, 2006.
-
(2006)
J Cell Biochem
, vol.99
, pp. 1021-1039
-
-
Pilat, M.J.1
Lorusso, P.M.2
-
22
-
-
33845286942
-
Vascular disrupting agents
-
Lippert JW III: Vascular disrupting agents. Bioorg Med Chem 15: 605-615, 2007.
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 605-615
-
-
Lippert III, J.W.1
-
23
-
-
0028878040
-
Phase I and pharmacology study of flavone acetic acid administered two or three times weekly without alkalinization
-
De Forni M, Chabot GG, Armand JP, Gouyette A, Klink-Alak M and Recondo G: Phase I and pharmacology study of flavone acetic acid administered two or three times weekly without alkalinization. Cancer Chemother Pharmacol 35: 219-224, 1995.
-
(1995)
Cancer Chemother Pharmacol
, vol.35
, pp. 219-224
-
-
De Forni, M.1
Chabot, G.G.2
Armand, J.P.3
Gouyette, A.4
Klink-Alak, M.5
Recondo, G.6
-
24
-
-
0024418074
-
Synthesis and anti-tumour activity of topologically-related analogues of flavoneacetic acid
-
Atwell GJ, Rewcastle GW, Baguley BC and Denny WA: Synthesis and anti-tumour activity of topologically-related analogues of flavoneacetic acid. Anticancer Drug Des 4: 161-169, 1989.
-
(1989)
Anticancer Drug Des
, vol.4
, pp. 161-169
-
-
Atwell, G.J.1
Rewcastle, G.W.2
Baguley, B.C.3
Denny, W.A.4
-
25
-
-
0026079805
-
Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid
-
Rewcastle GW, Atwell GJ, Baguley BC, Boyd M, Thomsen LL, Zhuang L and Denny WA: Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid. J Med Chem 34: 2864-2870, 1991.
-
(1991)
J Med Chem
, vol.34
, pp. 2864-2870
-
-
Rewcastle, G.W.1
Atwell, G.J.2
Baguley, B.C.3
Boyd, M.4
Thomsen, L.L.5
Zhuang, L.6
Denny, W.A.7
-
26
-
-
0025981526
-
Potential antitumor agents. 62. Structureactivity relationships for tricyclic compounds related to the colon tumor active drug 9-oxo-9H-xanthene-4-acetic acid
-
Rewcastle GW, Atwell GJ, Palmer BD, Boyd PD, Baguley BC and Denny WA: Potential antitumor agents. 62. Structureactivity relationships for tricyclic compounds related to the colon tumor active drug 9-oxo-9H-xanthene-4-acetic acid. J Med Chem 34: 491-496, 1991.
-
(1991)
J Med Chem
, vol.34
, pp. 491-496
-
-
Rewcastle, G.W.1
Atwell, G.J.2
Palmer, B.D.3
Boyd, P.D.4
Baguley, B.C.5
Denny, W.A.6
-
27
-
-
0026100365
-
Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9Hxanthene-4-acetic acids
-
Rewcastle GW, Atwell GJ, Li ZA, Baguley BC and Denny WA: Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9Hxanthene-4-acetic acids. J Med Chem 34: 217-222, 1991.
-
(1991)
J Med Chem
, vol.34
, pp. 217-222
-
-
Rewcastle, G.W.1
Atwell, G.J.2
Li, Z.A.3
Baguley, B.C.4
Denny, W.A.5
-
28
-
-
34247266033
-
Phase Ib/II study of DMXAA combined with carboplatin and paclitaxel in non-small cell lung cancer (NSCLC)
-
and investigators A-Sg
-
McKeage M and investigators A-Sg: Phase Ib/II study of DMXAA combined with carboplatin and paclitaxel in non-small cell lung cancer (NSCLC). J Clin Oncol 24: 7102, 2006.
-
(2006)
J Clin Oncol
, vol.24
, pp. 7102
-
-
McKeage, M.1
-
29
-
-
1042263997
-
Induction of tumour necrosis factor and interferon-gamma in cultured murine splenocytes by the antivascular agent DMXAA and its metabolites
-
Wang LC, Reddy CB, Baguley BC, Kestell P, Sutherland R and Ching LM: Induction of tumour necrosis factor and interferon-gamma in cultured murine splenocytes by the antivascular agent DMXAA and its metabolites. Biochem Pharmacol 67: 937-945, 2004.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 937-945
-
-
Wang, L.C.1
Reddy, C.B.2
Baguley, B.C.3
Kestell, P.4
Sutherland, R.5
Ching, L.M.6
-
30
-
-
0025082527
-
Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity
-
Engelmann H, Holtmann H, Brakebusch C, Avni YS, Sarov I, Nophar Y, Hadas E, Leitner O and Wallach D: Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. J Biol Chem 265: 14497-14504, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 14497-14504
-
-
Engelmann, H.1
Holtmann, H.2
Brakebusch, C.3
Avni, Y.S.4
Sarov, I.5
Nophar, Y.6
Hadas, E.7
Leitner, O.8
Wallach, D.9
-
31
-
-
0037068317
-
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice
-
Zhao L, Ching LM, Kestell P and Baguley BC: The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. Br J Cancer 87: 465-470, 2002.
-
(2002)
Br J Cancer
, vol.87
, pp. 465-470
-
-
Zhao, L.1
Ching, L.M.2
Kestell, P.3
Baguley, B.C.4
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