New derivatives of xanthenone-4-acetic acid: Synthesis, pharmacological profile and effect on TNF-α and NO production by human immune cells

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 12, 2006, Pages 4101-4109

  Gobbi, Silvia ^a   Belluti, Federica ^a   Bisi, Alessandra ^a   Piazzi, Lorna ^a   Rampa, Angela ^a   Zampiron, Antonella ^b   Barbera, Mariagnese ^b   Caputo, Anna ^b   Carrara, Maria ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

DMXAA; Human monocytes; Nitric oxide; TNF

Indexed keywords

3 (2 CHLOROETHOXY) 4 ALLYLXANTHENONE; 3 (2 CHLOROETHOXY)XANTHENONE 4 ACETIC ACID; 3 (2 IODOETHOXY)XANTHENONE 4 ACETIC ACID; 3 (3 CHLOROPROPOXY) 4 ALLYLXANTHENONE; 3 (3 CHLOROPROPOXY)XANTHENONE 4 ACETIC ACID; 3 (3 IODOPROPOXY)XANTHENONE 4 ACETIC ACID; 3 (4 CHLOROBUTOXY) 4 ALLYLXANTHENONE; 3 (4 CHLOROBUTOXY)XANTHENONE 4 ACETIC ACID; 3 (4 IODOBUTOXY)XANTHENONE 4 ACETIC ACID; 3 (5 CHLOROPENTOXY) 4 ALLYLXANTHENONE; 3 (5 CHLOROPENTOXY)XANTHENONE 4 ACETIC ACID; 3 (5 IODOPENTOXY)XANTHENONE 4 ACETIC ACID; 5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; 6 (2 CHLOROETHOXY)XANTHENONE 4 ACETIC ACID; 6 (2 CHLOROETHOXY)XANTHENONE 4 ACETIC ACID METHYL ESTER; 6 (2 IODOETHOXY)XANTHENONE 4 ACETIC ACID; 6 (3 CHLOROPROPOXY)XANTHENONE 4 ACETIC ACID; 6 (3 CHLOROPROPOXY)XANTHENONE 4 ACETIC ACID METHYL ESTER; 6 (3 IODOPROPOXY)XANTHENONE 4 ACETIC ACID; 6 (4 CHLOROBUTOXY)XANTHENONE 4 ACETIC ACID; 6 (4 CHLOROBUTOXY)XANTHENONE 4 ACETIC ACID METHYL ESTER; 6 (4 IODOBUTOXY)XANTHENONE 4 ACETIC ACID; 6 (5 CHLOROPENTOXY)XANTHENONE 4 ACETIC ACID; 6 (5 CHLOROPENTOXY)XANTHENONE 4 ACETIC ACID METHYL ESTER; 6 (5 IODOPENTOXY)XANTHENONE 4 ACETIC ACID; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHENE DERIVATIVE; XANTHONE 4 ACETIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CYTOLYSIS; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOCOMPETENT CELL; MONOCYTE;

CELL PROLIFERATION; HUMANS; LEUKOCYTES, MONONUCLEAR; MOLECULAR STRUCTURE; NITRIC OXIDE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA; XANTHENES; XANTHONES;

EID: 33646175026     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.02.003     Document Type: Article

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