Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex

European Journal of Immunology

Volumn 39, Issue 2, 2009, Pages 580-588

  Wan, Mimi ^a   Zhang, Jianmin ^a,c   Lai, Dazhi ^a   Jani, Anant ^a   Prestone Hurlburt, Paula ^a   Zhao, Lulu ^a   Ramachandran, Aruna ^b   Schnitzler, Gavin R ^b   Chi, Tian ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BAF27; CD4; Chromatin

Indexed keywords

BARRIER TO AUTOINTEGRATION FACTOR; BARRIER TO AUTOINTEGRATION FACTOR 57; CD4 ANTIGEN; HISTONE H1; PROTEIN BAF57; PROTEIN SWI; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SNF; UNCLASSIFIED DRUG; HISTONE; NONHISTONE PROTEIN; RUNX1 PROTEIN, MOUSE; SMARCE1 PROTEIN, MOUSE; SWI SNF B CHROMATIN REMODELING COMPLEX; SWI-SNF-B CHROMATIN-REMODELING COMPLEX; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; MUTANT; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN BINDING; RESTRICTION MAPPING; THYMOCYTE; WESTERN BLOTTING; ANIMAL; CHROMATIN; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION; SILENCER ELEMENT;

ANIMALS; ANTIGENS, CD4; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOMAL PROTEINS, NON-HISTONE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; GENE EXPRESSION REGULATION; HISTONES; MICE; MICE, KNOCKOUT; MUTATION; SILENCER ELEMENTS, TRANSCRIPTIONAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 60749093350     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838909     Document Type: Article

References (36)

1. Choudhary, P. and Varga-Weisz, P., ATP-dependent chromatin remodelling: Action and reaction. Subcell. Biochem. 2007. 41: 29-43.
2. Gangaraju, V. K. and Bartholomew, B., Mechanisms of ATP dependent chromatin remodeling. Mutat. Res. 2007. 618: 3-17.
3. Wang, W., The SWI/SNF family of ATP-dependent chromatin remodelers: Similar mechanisms for diverse functions. Curr. Top. Microbiol. Immunol. 2003. 274: 143-169.
4. Chi, T., A BAF-centred view of the immune system. Nat. Rev. Immunol. 2004. 4: 965-977.
5. de la Serna, I. L., Ohkawa, Y. and Imbalzano, A. N., Chromatin remodelling in mammalian differentiation: Lessons from ATP-dependent remodellers. Nat. Rev. Genet. 2006. 7: 461-473.
6. Wang, W., Chi, T., Xue, Y., Zhou, S., Kuo, A. and Crabtree, G. R., Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. Proc. Natl. Acad. Sci. USA 1998. 95: 492-498.
7. Phelan, M. L., Sif, S., Narlikar, G. J. and Kingston, R. E., Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Mol. Cell. 1999. 3: 247-253.
8. Nie, Z., Xue, Y., Yang, D., Zhou, S., Deroo, B. Archer, T. K. and Wang, W., A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol. Cell. Biol. 2000. 20: 8879-8888.
9. Oh, J., Sohn, D. H., Ko, M., Chung, H., Jeon, S. H. and Seong, R. H., BAF60a interacts with p53 to recruit the SWI/SNF complex. J. Biol. Chem. 2008. 283: 11924-11934.
10. Lickert, H., Takeuchi, J. K., Von Both, I., Walls, J. R., McAuliffe, F., Adamson, S. L., Henkelman, R. M. et al., Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature 2004. 432: 107-112.
11. Wu, J. I., Lessard, J., Olave, I. A., Qiu, Z., Ghosh, A., Graef, I. A. and Crabtree, G. R., Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 2007. 56: 94-108.
12. Hendricks, K. B., Shanahan, F. and Lees, E., Role for BRG1 in cell cycle control and tumor suppression. Mol. Cell. Biol. 2004. 24: 362-376.
13. Trotter, K. W. and Archer, T. K., Reconstitution of glucocorticoid receptor-dependent transcription in vivo. Mol. Cell. Biol. 2004. 24: 3347-3358.
14. Batsche, E., Yaniv, M. and Muchardt, C., The human SWI/SNF subunit Brm is a regulator of alternative splicing. Nat. Struct. Mol. Biol. 2006. 13: 22-29.
15. Taniuchi, I., Ellmeier, W, and Littman, D. R., The CD4/CD8 lineage choice: New insights into epigenetic regulation during T cell development. Adv. Immunol. 2004. 83: 55-89.
16. Gebuhr, T. C., Kovalev, G. I., Bultman, S., Godfrey, V., Su, L. and Magnuson, T., The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development. J. Exp. Med. 2003. 198: 1937-1949.
17. Chi, T. H., Wan, M., Zhao, K., Taniuchi, I., Chen, L., Littman, D. R. and Crabtree, G. R., Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature 2002. 418: 195-199.
18. Chi, T. H., Wan, M., Lee, P.. P., Akashi, K., Metzger, D., Chambon, P., Wilson, C. B. and Crabtree, G. R., Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity 2003. 19: 169-182.
19. Yu, M., Wan, M., Zhang, J., Wu, J., Khatri, R. and Chi T., Nucleoprotein structure of the CD4 locus: Implications for the mechanisms underlying CD4 regulation during T cell development. Proc. Natl. Acad. Sci. USA 2008. 105: 3873-3878.
20. Zhao, K., Wang, W., Rando, O. J., Xue, Y., Swiderek, K., Kuo, A. and Crabtree, G. R., Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 1999. 95: 625-636.
21. Bresnick, E. H., Bustin, M., Marsaud, V., Richard-Foy, H. and Hager, G. L., The transcniptionaliy-active MMTV promoter is depleted of histone H1. Nucleic Acids Res. 1992. 20: 273-278.
22. Flavin, M., Cappabianca, L., Kress, C., Thomassin, H. and Grange, T., Nature of the accessible chromatin at a glucocorticoid-responsive enhancer. Mol. Cell. Biol. 2004. 24: 7891-7901.
23. Taniuchi, I., Osato, M., Egawa, T., Sunshine, M. J., Bae, S. C., Komori, T., Ito, Y. and Littman, D. R., Differential requirements for Runx proteins in CD4 repression and epigenetic, silencing during T lymphocyte development. Cell 2002. 111: 621-633.
24. Sato, T., Ohno, S., Hayashi, T., Sato, C., Kohu, K., Satake, M. and Habu, S., Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes. Immunity 2005. 22: 317-328.
25. Sawada, S. and Littman, D. R., A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines. Mol. Cell. Biol. 1993. 13: 5620-5628.
26. Williams, C. J., Naito, T., Arco, P. G., Seavitt, J. R., Cashman, S. M., De Souza, B., Qi, X. et al., The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity 2004. 20: 719-733.
27. Setoguchi, R., Tachibana, M., Naoe, Y., Muroi, S., Akiyama, K., Tezuka, C., Okuds, T. and Taniuchi, J., Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science 2008. 319: 822-825.
28. Yuan, G. C., Liu, Y. J., Dion, M. F., Slack, M. D., Wu, L. F., Altschuler, S. J. and Rando, O. J., Genome-scale identification of nucleosome positions in S. cerevisiae. Science 2005. 309: 626-630.
29. Weinmann, A. S., Mitchell, D. M., Sanjabi, S., Bradley, M. N., Hoffmann, A., Liou, H. C. and Smale, S. T., Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat. Immunol. 2001. 2: 51-57.
30. Lomvardas, S. and Thanos, D., Nucleosome sliding via TBP DNA binding in vivo. Cell 2001. 106: 685-696.
31. Fragoso, G., John, S., Roberts, M. S. and Hager, G. L., Nucleosome positioning on the MMTV LTR results from the frequency-biased occupancy of multiple frames. Genes Dev. 1995. 9: 1933-1947.
32. Schones, D. E., Cui, K., Cuddapah, S., Roh, T. Y., Barski, A., Wang, Z., Wei, G. and Zhao, K., Dynamic regulation of nucleosome positioning in the human genome. Cell 2008. 132: 887-898.
33. Hill, D. A., Influence of linker histone H1 on chromatin remodeling. Biochem. Cell Biol. 2001. 79: 317-324.
34. Weinmann, A. S., Plevy, S. E. and Smale, S. T., Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription. Immunity 1999. 11: 665-675.
35. Chi, T., Yan, Z., Xue, Y. and Wang, W., Purification and functional analysis of the mammalian SWI/SNF-family of chromatin-remodeling complexes. Methods Enzymol. 2004. 377: 299-316.
36. Krishnakumar, R., Gamble, M. J., Frizzell, K. M., Berrocal, J. G., Kininis, M. and Kraus, W. L., Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes. Science 2008. 319: 819-821.