Demonstration of three-dimensional optical imaging using a confocal microscope based on a liquid-crystal electronic lens

Optical Engineering

Volumn 47, Issue 6, 2008, Pages

  Riza, Nabeel A ^a   Sheikh, Mumtaz ^a   Webb Wood, Grady ^a   Kik, Pieter G ^a  

^a UNIVERSITY OF CENTRAL FLORIDA   (United States)

Author keywords

Liquid crystal; microscopy; optical imaging

Indexed keywords

CONFOCAL MICROSCOPES; CORRELATION VALUE; ELECTRONIC LENS; GLASS SLIDES; IMAGE SIZES; IMAGING ERRORS; LASER WAVELENGTH; MECHANICAL FORCE; MICRO-OBJECTIVES; MICROSCOPE IMAGES; MICROSCOPY SYSTEMS; OPTICAL IMAGING; OPTICAL LENS; ORIGINAL SAMPLE; TRANSVERSE MOTIONS;

BLOOD VESSELS; GLASS LASERS; IMAGE PROCESSING; LENSES; LIQUID CRYSTALS; MICROSCOPES; OPTICAL DATA PROCESSING; OPTICAL IMAGE STORAGE;

THREE DIMENSIONAL;

EID: 60749091134     PISSN: 00913286     EISSN: 15602303     Source Type: Journal    
DOI: 10.1117/1.2944135     Document Type: Article

References (38)

1. M., Minsky, " Microscopy apparatus, " U.S. Patent No. 3,013,467 (1961).
2. T., Wilson, Confocal Microscopy, Academic Press, San Diego (1990).
3. T., Corle and G., Kino, Confocal Scanning Optical Microscopy and Related Imaging Systems, Academic Press, San Diego (1996).
4. M., Rajadhyaksha, R., Anderson, and R., Webb, " Video-rate confocal scanning laser microscope for imaging human tissues in vivo, ", Appl. Opt., 38 (10), 2105-2115 (1999). apo APOPAI 0003-6935 10.1364/AO.38.002105 (Pubitemid 129306953)
5. R. L., Forward, " Passive beam deflecting apparatus, " U.S. Patent No. 3,612,659 (1971).
6. G., Molesini, G., Pedrini, P., Poggi, and F., Quercioli, " Focus wavelength encoded optical profilometer, ", Opt. Commun., 49 (4), 229-233 (1984). opc OPCOB8 0030-4018 10.1016/0030-4018(84)90179-2 (Pubitemid 14547945)
7. M. A., Browne, O., Akinyemi, and A., Boyde, " Confocal surface profiling using chromatic aberration, ", Scanning, 14, 145-153 (1992). scy SCNNDF 0161-0457
8. B., Picard, " Method for the scanning confocal light optical microscopic & indepth examination of an extended field & devices for implementing said method, " U.S. Patent No. 4,965,441 (1990).
9. H. J., Tiziani and H. M., Uhde, " Three dimensional image sensing by chromatic confocal microscopy, ", Appl. Opt., 33 (10), 1838-1843 (1994). apo APOPAI 0003-6935
10. N. A., Riza, " Photonically controlled ultrasonic arrays: scenarios and systems, " in, IEEE Ultrasonics Symp., Vol. 2, pp. 1545-1550 (1996).
11. N. A., Riza, " Photonically controlled ultrasonic probes, " U.S. Patent No. 5,718,226 (1998).
12. G. J., Tearney, R. H., Webb, and B. E., Bouma, " Spectrally encoded confocal microscopy, ", Opt. Lett., 23 (15), 1152-1154 (1998). opl OPLEDP 0146-9592 10.1364/OL.23.001152 (Pubitemid 128597690)
13. N. A., Riza and Y., Huang, " High speed optical scanner for multi-dimensional beam pointing and acquisition, " in, IEEE LEOS Annual Meeting, Vol. 1, pp. 184-185 (1999). (Pubitemid 30525659)
14. N. A., Riza and Z., Yaqoob, " High-speed fiber-optic probe for dynamic blood analysis measurements, ", Proc. SPIE, 4163, 18-23 (August 2000). spi PSISDG 0277-786X (Pubitemid 32227469)
15. Z., Yaqoob, A. A., Rizvi, and N. A., Riza, " Free-space wavelength multiplexed optical scanner, ", Appl. Opt., 40 (35), 6425-6438 (2001). apo APOPAI 0003-6935 10.1364/AO.40.006425
16. Z., Yaqoob and N. A., Riza, " Free-space wavelength-multiplexed optical scanner demonstration, ", Appl. Opt., 41 (26), 5568 (2002). apo APOPAI 0003-6935 10.1364/AO.41.005568
17. G. J., Tearney, M., Shishkov, and B. E., Bouma, " Spectrally encoded miniature endoscopy, ", Opt. Lett., 27 (6), 412-414 (2002). opl OPLEDP 0146-9592 10.1038/415412a (Pubitemid 34102988)
18. Z., Yaqoob, M., Arain, and N. A., Riza, " Wavelength multiplexed optical scanner using photothermorefractive glasses, ", Appl. Opt., 42 (26), 5251 (2003). apo APOPAI 0003-6935 10.1364/AO.42.005251
19. Z., Yaqoob and N. A., Riza, " Low loss wavelength-multiplexed optical scanners using volume Bragg gratings for transmit-receive lasercom systems, ", Opt. Eng., 43 (5), 1128-1135 (2004). gar OPEGAR 0091-3286 10.1117/1.1690765
20. N. A., Riza, " Wavelength switched fiber-optically controlled ultrasonic intracavity probes, " in, IEEE LEOS Ann. Mtg. Digest, pp. 31-36 (1996).
21. Z., Yaqoob and N. A., Riza, " High-speed scanning probes for internal and external cavity biomedical optics, " in, OSA Biomedical Topical Meeting, pp. 381-383 (2002).
22. N. A., Riza, " Multiplexed optical scanner technology, " U.S. Patent No. 6,687,036 (2004).
23. N. A., Riza and A., Bokhari, " Agile optical confocal microscopy instrument architectures for high flexibility imaging, " in, Three Dimensional Confocal Microscopies, BIOS 2004 Biomedical Optics, Photonics West, Proc. SPIE, 5324, 77-88 (Jan. 2004). (Pubitemid 40108915)
24. B., Qi, A. P., Himmer, L. M., Gordon, X. D. V., Yang, L. D., Dickensheets, and I. A., Vitkin, " Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror, ", Opt. Commun., 232 (1-6), 123-128 (2004). opc OPCOB8 0030-4018 10.1016/j.optcom.2004.01.015
25. A., Divetia, T., Hsieh, J., Zhang, Z., Chen, M., Bachman, and G., Li, " Dynamically focused optical coherence tomography for endoscopic applications, ", Appl. Phys. Lett., 86, 103902 (2005). apl APPLAB 0003-6951 10.1063/1.1879096 (Pubitemid 40597147)
26. G. D., Reddy and P., Saggau, " Fast three-dimensional laser scanning scheme using acousto-optic deflectors, ", J. Biomed. Opt., 10 (6), 064038 (2005). jbo JBOPFO 1083-3668 10.1117/1.2141504 (Pubitemid 44255990)
27. S. A., Khan and N. A., Riza, " Demonstration of a no-moving-parts axial scanning confocal microscope using liquid crystal optics, ", Opt. Commun., 265 (2), 461-467 (2006). opc OPCOB8 0030-4018 (Pubitemid 44314141)
28. N. A., Riza, M., Sheikh, G., Webb-Wood, and P., Kik, " Demonstration of three dimensional imaging of blood vessel using a no-moving parts electronic lens-based optical confocal microscope, " in, Conf. MI03: Physics of Medical Imaging, SPIE Medical Imaging, Proc. SPIE, 6510, 65100J1-5 (Feb. 2007).
29. G., Vdovin, A., Naumov, M., Loktev, V., Belopukhov, F., Vladimirov, and G., Love, " Wave front control systems based on modal liquid crystal lenses, ", Rev. Sci. Instrum., 71 (9), 3290-3297 (2000). rsi RSINAK 0034-6748 10.1063/1.1288256
30. N. A., Riza and S. A., Khan, " Polarization multiplexed optical scanner, ", Opt. Lett., 28 (7), 561-563 (2003). opl OPLEDP 0146-9592
31. R. C., Gonzalez and R. E., Woods, Digital Image Processing, 3rd ed., Addison-Wesley, Reading, MA (1992).
32. M., Gu and C. J. R., Sheppard, " Effects of defocus and primary spherical aberration on three-dimensional coherent transfer functions in confocal microscopes, ", Appl. Opt., 31 (14), 2541-2549 (1992). apo APOPAI 0003-6935
33. V., Mahajan, " Axial irradiance of a focused beam, ", J. Opt. Soc. Am. A, 22 (9), 1814-1823 (2005). joa JOAOD6 0740-3232 (Pubitemid 41372908)
34. L., Sherman, J. Y., Ye, O., Albert, and T. B., Norris, " Adaptive correction of depth-induced aberrations in multiphoton scanning microscopy using adeformable mirror, ", J. Microsc., 206 (1), 65-71 (2002). jmi JMICAR 0022-2720 10.1046/j.1365-2818.2002.01004.x (Pubitemid 34534138)
35. Y., Yasuno, T. F., Wiesendanger, A. K., Ruprecht, S., Makita, T., Yatagai, and H. J., Tiziani, " Wavefront-flatness evaluation by wavefront-correlation-information-entropy method and its application for adaptive confocal microscope, ", Opt. Commun., 232 (1-6), 91-97 (2004). opc OPCOB8 0030-4018
36. S., Kuiper and B. H. W., Hendriks, " Variable-focus liquid lens for miniature cameras, ", Appl. Phys. Lett., 85, 1128-1130 (Aug. 16, 2004). apl APPLAB 0003-6951 10.1063/1.1779954
37. B., Berge and J., Peseux, " Variable focal lens controlled by an external voltage: an application of electrowetting, ", Eur. Phys. J. E, 3, 159-163 (2000). 9fm EPJSFH 1292-8941 10.1007/s101890070029
38. G., Vdovin, P. M., Sarro, and S., Middelhoek, " Technology and applications of micromachined adaptive mirrors, ", Opt. Eng., 36 (5), 1382-1390 (1997). gar OPEGAR 0091-3286 10.1117/1.601334 (Pubitemid 127655893)