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Volumn 27, Issue 1, 2009, Pages 82-87

Polymorphism in the methylenetetrahydrofolate reductase (C677T) gene and homocysteine levels: A comparison in Brazilian patients with coronary arterial disease, ischemic stroke and peripheral arterial obstructive disease

Author keywords

Coronary arterial disease and peripheral arterial obstructive disease; Homocysteine; Ischemic stroke; MTHFR

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CHOLESTEROL; CYTOSINE; HOMOCYSTEINE; LOW DENSITY LIPOPROTEIN; THREONINE;

EID: 60649093092     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-007-0172-z     Document Type: Article
Times cited : (29)

References (37)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R (1999) Atherosclerosis: An inflammatory disease. N Engl J Med 340:115-126
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 2
    • 0035799341 scopus 로고    scopus 로고
    • Inflammation and thrombosis: The clot thickens
    • Libby P, Simon DI (2001) Inflammation and thrombosis: The clot thickens. Circulation 103:1718-1720
    • (2001) Circulation , vol.103 , pp. 1718-1720
    • Libby, P.1    Simon, D.I.2
  • 3
    • 0141730235 scopus 로고    scopus 로고
    • Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part II
    • Luscher TF, Creager MA, Beckman JA, Cosentino F (2003) Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part II. Circulation 108:1655-1661
    • (2003) Circulation , vol.108 , pp. 1655-1661
    • Luscher, T.F.1    Creager, M.A.2    Beckman, J.A.3    Cosentino, F.4
  • 4
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ (2000) Atherosclerosis. Nature 407:233-241
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 5
    • 0003062329 scopus 로고    scopus 로고
    • Atherosclerosis
    • In: Fauci AS, Braunwald E, Isselbacher KJ et al. (eds). 14th edn. McGraw-Hill, New York
    • Libby P (1998) Atherosclerosis. In: Fauci AS, Braunwald E, Isselbacher KJ et al. (eds). Harrison's principles of internal medicine, 14th edn. McGraw-Hill, New York
    • (1998) Harrison's Principles of Internal Medicine
    • Libby, P.1
  • 6
    • 0036773399 scopus 로고    scopus 로고
    • Coronary artery disease in women: A review of emerging cardiovascular risk factors
    • Nguyen VHD, Mclaughlin MA (2002) Coronary artery disease in women: A review of emerging cardiovascular risk factors. Mt Sinai J Med 69:338-349
    • (2002) Mt Sinai J Med , vol.69 , pp. 338-349
    • Nguyen, V.H.D.1    Mclaughlin, M.A.2
  • 7
    • 10944224173 scopus 로고    scopus 로고
    • The relationship of cigarette smoking to peripheral arterial disease
    • Jeffrey T, Lu AB, Mark A, Creager MD (2004) The relationship of cigarette smoking to peripheral arterial disease. Rev Cardiovasc Med 5:189-193
    • (2004) Rev Cardiovasc Med , vol.5 , pp. 189-193
    • Jeffrey, T.1    Lu, A.B.2    Mark, A.3    Creager, M.D.4
  • 8
    • 0003731910 scopus 로고    scopus 로고
    • World Health Report World Health Organization, Geneva, Switzerland. Cited 30 Aug 2007
    • World Health Report (2002) Reducing risks, promoting healthy life. World Health Organization, Geneva, Switzerland. http://www.who.int/whr/2002. Cited 30 Aug 2007
    • (2002) Reducing Risks, Promoting Healthy Life
  • 9
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Prospective Studies Collaboration
    • Lewington S, Clarke R, Qizilbash N, Peto R, Collins R (2002) Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Prospective Studies Collaboration. Lancet 360:1903-1913
    • (2002) Lancet , vol.360 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 11
    • 0028889807 scopus 로고
    • Overweight prevalence and trends for children and adolescents - The National and Nutrition Examination Surveys, 1963 to 1991
    • Troiano RP, Flegal KM, Kukzmarski RJ, Campbell SM, Johnson CL (1995) Overweight prevalence and trends for children and adolescents - the National and Nutrition Examination Surveys, 1963 to 1991. Arch Pediatr Adolesc Med 149:1085-1091
    • (1995) Arch Pediatr Adolesc Med , vol.149 , pp. 1085-1091
    • Troiano, R.P.1    Flegal, K.M.2    Kukzmarski, R.J.3    Campbell, S.M.4    Johnson, C.L.5
  • 14
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A commom mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, Goyette P, Shepparó CA, Matthews RG (1995). A candidate genetic risk factor for vascular disease: A commom mutation in methylenetetrahydrofolate reductase. Nat Genet 10:111-113
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3    Goyette, P.4    Shepparó, C.A.5    Matthews, R.G.6
  • 15
    • 4344575902 scopus 로고    scopus 로고
    • European guidelines on cardiovascular disease prevention in clinical practice: Third joint task force of European and other societies on cardiovascular disease prevention in clinical practice
    • De Backer G, Ambrosioni E, Broch-Johnsen K et al (2003 European guidelines on cardiovascular disease prevention in clinical practice: third joint task force of European and other societies on cardiovascular disease prevention in clinical practice. Eur J Card Prev Reh 10:S1-S10
    • (2003) Eur J Card Prev Reh , vol.10
    • De Backer, G.1    Ambrosioni, E.2    Broch-Johnsen, K.3
  • 16
    • 1942438624 scopus 로고    scopus 로고
    • Effect of C677T methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine levels in ethnic groups
    • Gasparovic J, Raslova K, Basistova Z et al (2004). Effect of C677T methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine levels in ethnic groups. Physiol Res 53:215-218
    • (2004) Physiol Res , vol.53 , pp. 215-218
    • Gasparovic, J.1    Raslova, K.2    Basistova, Z.3
  • 17
    • 0033960892 scopus 로고    scopus 로고
    • Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults
    • Voetsch B, Damasceno BP, Camargo EC et al (2000) Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults. Thromb Haemost 83:229-233
    • (2000) Thromb Haemost , vol.83 , pp. 229-233
    • Voetsch, B.1    Damasceno, B.P.2    Camargo, E.C.3
  • 18
    • 0035057410 scopus 로고    scopus 로고
    • C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: Incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease
    • Hanson NQ, Aras O, Yang F, Tsai MY (2001) C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: Incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular disease. Clin Chem 47:661-666
    • (2001) Clin Chem , vol.47 , pp. 661-666
    • Hanson, N.Q.1    Aras, O.2    Yang, F.3    Tsai, M.Y.4
  • 19
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in vascular disease. The Heart Outcomes Prevention Evaluation (HOPE)
    • Lonn E, Yusuf S, Phil D (2006). Homocysteine lowering with folic acid and B vitamins in vascular disease. The Heart Outcomes Prevention Evaluation (HOPE). N Engl J Med 354:1567-1577
    • (2006) N Engl J Med , vol.354 , pp. 1567-1577
    • Lonn, E.1    Yusuf, S.2    Phil, D.3
  • 20
    • 33645796222 scopus 로고    scopus 로고
    • Homocysteine lowering and cardiovascular events after acute myocardial infarction. For the NORVIT Trial Investigators
    • Bonaa KH, Njolstad I, Ueland PM et al (2006). Homocysteine lowering and cardiovascular events after acute myocardial infarction. For the NORVIT Trial Investigators. N Engl J Med 354:1578-1588
    • (2006) N Engl J Med , vol.354 , pp. 1578-1588
    • Bonaa, K.H.1    Njolstad, I.2    Ueland, P.M.3
  • 21
    • 1342309318 scopus 로고    scopus 로고
    • Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial
    • Toole JF, Malinow MR, Chambless LE et al (2004) Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 291:565-575
    • (2004) JAMA , vol.291 , pp. 565-575
    • Toole, J.F.1    Malinow, M.R.2    Chambless, L.E.3
  • 23
    • 33644693101 scopus 로고    scopus 로고
    • Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease
    • Stott DJ, MacIntosh G, Lowe GD et al (2005) Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. Am J Clin Nutr 82:1320-1326
    • (2005) Am J Clin Nutr , vol.82 , pp. 1320-1326
    • Stott, D.J.1    MacIntosh, G.2    Lowe, G.D.3
  • 24
    • 0031821779 scopus 로고    scopus 로고
    • Homocysteine and vitamins in cardiovascular disease
    • Jacobsen DW (1998) Homocysteine and vitamins in cardiovascular disease. Clin Chem 44:1833-1843
    • (1998) Clin Chem , vol.44 , pp. 1833-1843
    • Jacobsen, D.W.1
  • 25
    • 0036526239 scopus 로고    scopus 로고
    • Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients
    • Morelli VM, Lourenco DM, D'Almeida V et al (2002) Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients. Blood Coagul Fibrinolysis 13:271-275
    • (2002) Blood Coagul Fibrinolysis , vol.13 , pp. 271-275
    • Morelli, V.M.1    Lourenco, D.M.2    D'Almeida, V.3
  • 26
    • 33846378138 scopus 로고    scopus 로고
    • Evaluation of MTHFR C677T gene polymorphism and homocysteine level in coronary atherosclerotic disease
    • Muniz MT, Siqueira ER, Fonseca RA et al (2006). Evaluation of MTHFR C677T gene polymorphism and homocysteine level in coronary atherosclerotic disease. Arq Bras Endocrinol Metabol 50:1059-1065
    • (2006) Arq Bras Endocrinol Metabol , vol.50 , pp. 1059-1065
    • Muniz, M.T.1    Siqueira, E.R.2    Fonseca, R.A.3
  • 28
    • 33947608269 scopus 로고    scopus 로고
    • Homocysteine and metilenetetrahydrofolate reductase (MTHFR) in subjects submitted to coronary angiography
    • Lima LM, Carvalho MG, Sabino AP et al (2006) Homocysteine and metilenetetrahydrofolate reductase (MTHFR) in subjects submitted to coronary angiography. Arq Bras Cardiol 88:167-172
    • (2006) Arq Bras Cardiol , vol.88 , pp. 167-172
    • Lima, L.M.1    Carvalho, M.G.2    Sabino, A.P.3
  • 29
    • 1542515013 scopus 로고    scopus 로고
    • Validation of a new method of detecting peripheral artery disease by determination of ankle-brachial index using an automatic blood pressure device
    • Benchimol A, Bernard V, Pillois X, Hong NT, Benchimol D, Bonnet J (2004) Validation of a new method of detecting peripheral artery disease by determination of ankle-brachial index using an automatic blood pressure device. Angiology 55:127-134
    • (2004) Angiology , vol.55 , pp. 127-134
    • Benchimol, A.1    Bernard, V.2    Pillois, X.3    Hong, N.T.4    Benchimol, D.5    Bonnet, J.6
  • 30
    • 0000677439 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma, without the use of preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredickison DS (1972) Estimation of the concentration of low density lipoprotein cholesterol in plasma, without the use of preparative ultracentrifuge. Clin Chem 18:449-452
    • (1972) Clin Chem , vol.18 , pp. 449-452
    • Friedewald, W.T.1    Levy, R.I.2    Fredickison, D.S.3
  • 31
    • 0038167784 scopus 로고    scopus 로고
    • The effects of hyperhomocysteinemia on the presence, extent, and severity of coronary artery disease
    • Bozkurt A, Toyaksi H, Acartürk E, Tuli A, Cayli M (2003) The effects of hyperhomocysteinemia on the presence, extent, and severity of coronary artery disease. Jpn Heart J 44:357-368
    • (2003) Jpn Heart J , vol.44 , pp. 357-368
    • Bozkurt, A.1    Toyaksi, H.2    Acartürk, E.3    Tuli, A.4    Cayli, M.5
  • 32
    • 0033547813 scopus 로고    scopus 로고
    • Homocysteine, diet, and cardiovascular diseases: A statement for healthcare professionals from the Nutrition Committee, American Heart Association
    • Malinow MR, Bostom AG, Krauss RM (1999) Homocysteine, diet, and cardiovascular diseases: A statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation 99:178-182
    • (1999) Circulation , vol.99 , pp. 178-182
    • Malinow, M.R.1    Bostom, A.G.2    Krauss, R.M.3
  • 33
    • 0034723761 scopus 로고    scopus 로고
    • Blood levels of homocysteine and increased risks of cardiovascular disease. Causal or casual?
    • Christen W, Ajani U, Glynn R (2000) Blood levels of homocysteine and increased risks of cardiovascular disease. Causal or casual? Arch Intern Med 169:422-434
    • (2000) Arch Intern Med , vol.169 , pp. 422-434
    • Christen, W.1    Ajani, U.2    Glynn, R.3
  • 35
    • 1342288111 scopus 로고    scopus 로고
    • Serum total homocysteine levels and the prevalence of folic acid deficiency and C677T mutation at the MTHFR gene in an indigenous population of Amazonia: The relationship of homocysteine with other cardiovascular risk factors
    • Tavares EF, Vieira-Filho JP, Andriolo A et al (2004) Serum total homocysteine levels and the prevalence of folic acid deficiency and C677T mutation at the MTHFR gene in an indigenous population of Amazonia: The relationship of homocysteine with other cardiovascular risk factors. Ethn Dis 14:49-56
    • (2004) Ethn Dis , vol.14 , pp. 49-56
    • Tavares, E.F.1    Vieira-Filho, J.P.2    Andriolo, A.3
  • 36
    • 0035996584 scopus 로고    scopus 로고
    • Homocysteine levels in men and women of different ethnic and cultural background living in England
    • Cappuccio FP, Bell R, Perry IJ et al (2002). Homocysteine levels in men and women of different ethnic and cultural background living in England. Atherosclerosis 164:95-102
    • (2002) Atherosclerosis , vol.164 , pp. 95-102
    • Cappuccio, F.P.1    Bell, R.2    Perry, I.J.3
  • 37
    • 0031902128 scopus 로고    scopus 로고
    • Prevalence of the mutation C677 T in the methylenetetrahydrofolate reductase gene among distinct ethnic groups in Brazil
    • Arruda VR, Siqueira LH, Goncalves MS et al. (1998). Prevalence of the mutation C677 T in the methylenetetrahydrofolate reductase gene among distinct ethnic groups in Brazil. Am J Med Genet 78:332-335
    • (1998) Am J Med Genet , vol.78 , pp. 332-335
    • Arruda, V.R.1    Siqueira, L.H.2    Goncalves, M.S.3


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