Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10 in vitro

Clinical Science

Volumn 116, Issue 3, 2009, Pages 241-248

  Deng, Jingti ^a   James, Christian H ^b   Patel, Lisa ^c   Smith, Alberto ^d   Burnand, Kevin G ^d   Rahmoune, Hassan ^a   Lamb, Jonathan R ^e   Davis, Bill ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b GLAXOSMITHKLINE   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Atherosclerosis; Interleukin 10 (IL 10); Macrophage; Tribbles homologue 2 (Trb2); Unstable plaque

Indexed keywords

INTERLEUKIN 10; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN; REGULATOR PROTEIN; TRIBBLES PROTEIN 1; TRIBBLES PROTEIN 2; UNCLASSIFIED DRUG; CD68 ANTIGEN, HUMAN; CELL CYCLE PROTEIN; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; LOW DENSITY LIPOPROTEIN; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; SIGNAL PEPTIDE; TRIB1 PROTEIN, HUMAN; TRIB2 PROTEIN, HUMAN; TRIB3 PROTEIN, HUMAN;

ARTICLE; ATHEROSCLEROTIC PLAQUE; BRAIN ATHEROSCLEROSIS; CAROTID ARTERY DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE CONTROL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; UPREGULATION; BIOSYNTHESIS; CAROTID ENDARTERECTOMY; CELL CULTURE; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CAROTID ARTERY DISEASES; CELL CYCLE PROTEINS; CELLS, CULTURED; ENDARTERECTOMY, CAROTID; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-10; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPROTEINS, LDL; MACROPHAGES; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; RNA, MESSENGER;

EID: 60549108381     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080058     Document Type: Article

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