Activation of latent transforming growth factor beta during chlamydia trachomatis -induced murine pneumonia

Research in Microbiology

Volumn 147, Issue 4, 1996, Pages 251-262

  Williams, D M ^a,c   Grubbs, B G ^a   Park Snyder, S ^a   Rank, R G ^b   Bonewald, L F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c Division of Infectious Disease ^*  (United States)

Author keywords

Active and latent TGF ; Chlamydia trachomatis; Cytokine; Immunosuppression; Northern blot; RT PCR; TGF ; 1 and 2 isoforms

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ARTICLE; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; FEMALE; GENETIC REGULATION; GENETIC TRANSCRIPTION; IMMUNOSUPPRESSIVE TREATMENT; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PNEUMONIA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; FEMALE; LUNG; MALE; MICE; MICE, INBRED BALB C; PNEUMONIA, BACTERIAL; POLYMERASE CHAIN REACTION; RADIOIMMUNOASSAY; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029919730     PISSN: 09232508     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-2508(96)81385-4     Document Type: Article

References (47)

1. Assoian, R.K., Fleurdelys, B., Stevenson, H., Miller, P.L., Madtes, D., Raines, E., Ross, R. & Sporn, M. (1987), Expression and secretion of type beta TGF by activated human macrophages. Proc. Natl. Acad. Sci. USA, 84, 6020-6032.
2. Barral-Netto, M., Barrai, A., Brownell, C.E., Skeiky, Y., Ellingsworth, L., Twardzik, D. & Reed, S. (1992), Transforming growth factor beta in leishmanial infection: a parasite escape mechanism. Science, 257, 545-548.
3. Beatty, W.L., Morrison, R.P. & Byrne, G.I. (1994), Persistent chlamydiae from cell culture to a paradigm for chlamydial pathogenesis. Microbiol. Rev., 58, 686-699.
4. Bermudez, L. (1993), Production of TGFβ by M. avium infected human macrophages is associated with unresponsiveness to IFN-gamma. J. Immunol., 150, 1838-1845.
5. Bermudez, L.E., Covaro, G. & Remington, J. (1993), Infection of murine macrophages with T. gondii is associated with release of TGFβ and downregulation of expression of TNF receptors. Infect. Immun., 61, 4126-4130.
6. Bonewald, L.F. & Dallas, S.L. (1994), The role of active and latent TGFβ in bone formation. J. Cell. Biochem., 55, 350-357.
7. Bonewald, L.F., Wakefield, L., Oreffo, R.O.C., Escobedo, A., Twardzik, D.R. & Mundy, G.R. (1991), Latent forms of TGFβ derived from bone cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGFβ. Mol. Endocrinol., 5, 741-751.
8. Border, W., Noble, N.A., Yamamoto, T., Harper, J., Yamaguchi, J., Piershbacher, M. & Ruoslahti, E. (1992), Natural inhibitor of TGFβ protects against scarring in experimental kidney disease. Nature (Lond.), 360, 361-364.
9. Border, W.A. & Ruoslahti, E. (1992), Transforming growth factor-beta in disease: the dark side of tissue repair. J. Clin. Invest., 90, 1-7.
10. Broekelmann, T., Limper, A.H., Colby, T.V. & McDonald, J.A. (1991), TGFβ1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Natl Acad. Sci. USA, 88, 6642-6646.
11. Byrne, G.I., Grubbs, B., Dickey, T.J., Schachter, J. & Williams, D.M. (1987), A role for Interferon in recovery from pneumonia due to Chlamydia trachomatis in the mouse. J. Infect. Dis., 156, 993-996.
12. Chen, D. & Klebe, R. (1993), Controls for validation of relative reverse transcription PCR assays. PCR Meth. Appl., 3, 127-129.
13. Chen, D., Magnuson, V., Steffensen, B. & Klebe, R. (1993), Use of stock solutions to simplify mRNA quantitation by reverse transcription PCR assays. PCR Meth. Appl., 2, 351-353.
14. Coffman, R.L., Lebman, D.A. & Shrader, B. (1989), Transforming growth factor β specifically enhances IgA production by LPS-stimulated murine B lymphocytes. J. Exp. Med., 170, 1039-1044.
15. Dallas, S.L., Park-Snyder, S., Miyazono, K., Twardzik, D., Mundy, G.R. & Bonewald, L.F. (1994), Characterization and autoregulation of latent transforming growth factor β complex in osteoblast-like cell lines. J. Biol. Chem., 269, 1815-1822.
16. Danielpour, D., Dart, L., Flanders, K., Roberts, A. & Sporn, M. (1989), Immunodetection and quantitation of the two forms of TGF-β secreted by cells in culture. J. Cell. Physiol., 138, 79-86.
17. Denis, M. (1994), Neutralization of transforming growth factor-β1 in a mouse model of immune-induced lung fibrosis. Immunology, 82, 584-590.
18. Espevik, T., Figari, I.S., Ranges, G.E. & Palladino, M.A., Jr. (1988), Transforming growth factor-beta and recombinant human tumor necrosis factor-alpha reciprocally regulate the generation of lymphokine-activated killer cell activity. J. Immunol., 140, 2312-2316.
19. Fava, R., Olsen, N., Keski-Oja, J., Moses, H. & Pincus, T. (1989), Active and latent forms of transforming growth factor β activity in synovial effusions. J. Exp. Med., 169, 291-296.
20. Flaumenhaft, R., Kojima, S., Abe, M. & Rifkin, D.B. (1993), Activation of latent transforming growth factor β. Adv. Pharmacol., 24, 51-76.
21. Guagliardi, L.E., Byrne, G.I. & Paulnock, D.M. (1989), Differential modulation of lymphocyte proliferation responses and lymphokine secretion in mice during development of immunity to Chlamydia psittaci. Infect. Immun., 57, 1561-1567.
22. Igietseme, J.V., Ramsey, K.H., Magee, D.M., Williams, D.M., Kinsy, T.J. & Rank, R.G. (1993), Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific Th1 lymphocyte clone. Reg. Immunol., 5, 317-324.
23. Kehrl, J.H., Roberts, A.B., Wakefield, L.M., Jakowlew, S., Sporn, M.B. & Fauci, A.S. (1986a), Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes. J. Immunol., 137, 3855-3860.
24. Kehrl, J.H., Wakefield, L.M., Roberts, A.B., Jakowlew, S., Alvarez-mon, M., Derynck, R., Sporn, M.S. & Fauci, A.S. (1986b), Production of transforming growth factor beta by human lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med., 163, 1037-1050.
25. Kulkarni, A.B., Huh, G.G., Becker, D., Geiser, A., Lyght, M., Flanders, K., Roberts, A., Sporn, M., Ward, J. & Karlsson, S. (1993), Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA, 90, 770-774.
26. Magee, D.M., Smith, J.G., Bleicker, C., Carter, C.J., Bonewald, L.F., Schachter, J. & Williams, D.M. (1992), Chlamydia trachomatis pneumonia induces the in vivo production of IL-1 and IL-6. Infect. Immun., 60, 1217-1220.
27. Mule, J.J., Schwartz, S.L., Roberts, A.B., Sporn, M.B. & Rosenberg, S.A. (1988), Transforming growth factor beta inhibits the in vitro generation of lymphokine-activated killer cells and cytotoxic T cells. Cancer Immunol. Immunother., 26, 95-100.
28. Okuda, S., Languino, L.R., Ruoslahti, E. & Border, W.A. (1990), Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. J. Clin. Invest., 86, 453-462.
29. Oreffo, R.O.C., Mundy, G.R., Seyedin, S.M. & Bonewald, L.F. (1989), Activation of the bone-derived latent TGF beta complex by isolated osteoclasts. Biochem. Biophys. Res. Commun., 158, 817-823.
30. Perdue, T.D. & Brody, A.R. (1994), Distribution of transforming growth factor-beta 1, fibronectin, and smooth muscle actin in asbestos-induced pulmonary fibrosis in rats. J. Histochem. Cytochem., 42, 1061-1070.
31. Ramsey, K.H., Soderberg, L.S.F. & Rank, R.G. (1988), Resolution of chlamydial genital infection in β-cell-deficient mice and immunity to reinfection. Infect. Immun., 56, 1320-1325.
32. Shah, M., Foreman, D.M. & Ferguson, M.W.J. (1992), Control of scarring in adult wounds by neutralizing antibody to TGFβ. Lancet, 339, 213-214.
33. Shull, M.M., Ormsby, I., Kier, A.B., Pawlowski, S., Diebold, R.J., Yin, M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., Annunziata, N. & Doetschman, T. (1992), Targeted disruption of the mouse TGFβ1 gene results in multifocal inflammatory disease. Nature (Lond.), 359, 693-697.
34. Silva, J., Twardzik, D.R. & Reed, S.G. (1991), Regulation of T. cruzi infections in vitro and in vivo by TGFβ. J. Exp. Med., 174, 539-545.
35. Spaccapelo, R., Luigina, R., Tonnetti, L., Cenci, E., Mencacci, A., Del Sero, G., Tognellini, R., Reed, S.G., Puccetti, P. & Bistoni, F. (1995), TGFβ is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans. J. Immunol., 155, 1349-1360.
36. Svensson, L., Mardh, P.A. & Westrom, L. (1983), Infertility after acute salpingitis with special reference to Chlamydia trachomatis. Fertil. Steril., 40, 322-329.
37. Sue, H. & Caldwell, H.R. (1995), Kinetics of chlamydial antigen processing and presentation to T cells by paraformaldehyde-fixed bone marrow-derived macrophages. Infect. Immun., 63, 946-953.
38. Tada, T., Yabu, K. & Kobayashi, S. (1993), Detection of active form of transforming growth factor-β in cerebrospinal fluid of patients with glioma. Jpn. J. Cancer Res., 84, 544-548.
39. Taylor, H.R., Johnson, S.L., Schachter, J.S., Caldwell, H.D. & Prendergast, R.A. (1987), Pathogenesis of trachoma: the stimulus for inflammation. J. Immunol., 138, 3023-3027.
40. Twardzik, D.R., Mihovits, A., Ranchalis, I.E., Purchio, A.F., Ellingsworth, L. & Ruscetti, F.W. (1990), Gamma interferon induced activation of latent transforming growth factor beta by human monocytes. NY Acad. Sci., 593, 276-284.
41. Vanhee, D., Gosset, P., Wallaert, B., Voison, C. & Tonnel, A.B. (1994), Mechanisms of fibrosis in coal workers' pneumoconiosis. Increased production of platelet-derived growth factor, insulin-like growth factor, and transforming growth factor beta and relationship to disease. Am. J. Crit. Care Med., 150, 1049-1055.
42. Wahl, S. (1992), Transforming growth factor beta in inflammation: cause and a cure. J. Clin. Immunol., 12, 61-74.
43. Williams, D.M., Byrne, G.I., Grubbs, B., Marshall, T.J. & Schachter, J. (1988), A role in vivo for interferon gamma in control of pneumonia due to Chlamydia trachomatis in the mouse. Infect. Immun., 56, 3004-3006.
44. Williams, D.M., Magee, D.M., Bonewald, L.F., Smith, J.G., Byrne, G.I. & Schachter, J. (1990), A role in vivo for tumor necrosis factor alpha in host defense against Chlamydia trachomatis. Infect. Immun., 58, 1572-1577.
45. Williams, D., Schachter, J., Coalson, J. & Sumaya, C. (1984a), Cellular immunity to the mouse pneumonitis agent. J. Infect. Dis., 149, 630-639.
46. Williams, D.M., Schachter, J., Weiner, M.H. & Grubbs, B. (1984b), Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis). Infect. Immun., 45, 674-678.
47. Zhou, D., Munster, A. & Winchurch, R. (1991), Pathologic concentrations of IL-6 inhibit T-cell responses via induction of activation of TGFβ. FASEB J., 5, 2582-2585.