1α,25-Dihydroxyvitamin D3 inhibits pro-inflammatory cytokine and chemokine expression in human corneal epithelial cells colonized with Pseudomonas aeruginosa

Immunology and Cell Biology

Volumn 80, Issue 4, 2002, Pages 340-345

  Xue, Mei Lang ^a   Zhu, Hua ^a   Thakur, Archana ^a   Willcox, Mark ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

1 ,25 dihydroxyvitamin D3; Corneal epithelial cells; IL 1 ; IL 6; IL 8; Pseudomonas aeruginosa

Indexed keywords

CALCITRIOL; CHEMOKINE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; CELL GROWTH; CELL IMMORTALIZATION; CELL LINE; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROVOCATION TEST; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SUPERNATANT; BIOSYNTHESIS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INFLAMMATION; KINETICS; MICROBIOLOGY;

CALCITRIOL; CELL LINE; CHEMOKINES; CYTOKINES; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; INTERLEUKIN-6; INTERLEUKIN-8; KINETICS; PSEUDOMONAS AERUGINOSA; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; HUMANS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0035996446     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.80.4august.1.x     Document Type: Article

References (21)

1. Characterization of the inflammatory response induced by corneal infection with Pseudomonas aeruginosa
2. Proinflammatory cytokines
3. Early cytokine and chemokine gene expression during Pseudomonas aeruginosa corneal infection in mice
4. Prolonged elevation of IL-1 in Pseudomonas aeruginosa ocular infection regulates macrophage-inflammatory protein-2 production, polymorphonuclear neutrophil persistence, and corneal perforation
5. Macrophage inflammatory protein-2 is a mediator of polymorphonuclear neutrophil influx on ocular bacterial infection
6. 3 on Langerhans cell migration and corneal neovascularization in mice
7. 1-Alpha,25-dihydroxyvitamin D(3) inhibits angiogenesis in vitro and in vivo
8. 3 on inflammatory responses in psoriasis
9. 3 on interleukin-6 production and osteoclast-like cell formation in mouse bone marrow primary cultures
10. An SV40-immortalized human corneal epithelial cell line and its characterization
11. Beta-adrenergic and serotonergic responsiveness of rabbit corneal epithelial cells in culture
12. Pro-inflammatory cytokine/chemokine gene expression in human corneal epithelial cells colonized by Pseudomonas aeruginosa
13. Role of MIP-2 in neutrophil migration and tissue injury in the herpes simples virus-1-infected cornea
14. IL-1 beta primes IL-8-activated human neutrophils for elastase release, phospholipase D activity, and calcium flux
15. IL-1 beta does not cause neutrophil degranulation but does lead to IL-6, IL-8, and nitrite/ nitrate release when used in patients with cancer
16. 3 on cytokine production by human corneal epithelial cells
17. Effects of exogenous interleukin-6 during Pseudomonas aeruginosa corneal infection
18. Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines
19. Regulation of cytokine production in the human thymus: Epidermal growth factor and transforming growth factor alpha regulate mRNA concentrations of interleukin 1 alpha (IL-1 alpha), IL-1 beta, and IL-6 in human thymic epithelial cells at a post-transcriptional concentration
20. 3 inhibits cytokine production by human blood monocytes at the post-transcriptional concentration
21. 3 as a natural regulator of human immune functions