Human initiator caspases trigger apoptotic and autophagic phenotypes in Saccharomyces cerevisiae

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1793, Issue 3, 2009, Pages 561-571

  Lisa Santamaría, Patricia ^a   Neiman, Aaron M ^b   Cuesta Marbán, Álvaro ^a   Mollinedo, Faustino ^a   Revuelta, José L ^a   Jiménez, Alberto ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Apoptosis; Autophagy; Caspase; Cell death; Oxidative stress; Yeast

Indexed keywords

ACTIN; CASPASE 10; CASPASE 8; HYDROXYUREA; INITIATOR CASPASE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE ARREST; CELL VACUOLE; CELL WALL; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOSKELETON; DNA REPLICATION; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; YEAST CELL;

APOPTOSIS; AUTOPHAGY; CASPASE 10; CASPASE 8; CELL CYCLE; CELL DEATH; HUMANS; JURKAT CELLS; PHENOTYPE; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 60549085728     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2008.12.016     Document Type: Article

References (50)

1. Ho P.K., and Hawkins C.J. Mammalian initiator apoptotic caspases. FEBS J. 272 (2005) 5436-5453
2. Bao Q., and Shi Y. Apoptosome: a platform for the activation of initiator caspases. Cell Death Differ. 14 (2007) 56-65
3. Festjens N., Cornelis S., Lamkanfi M., and Vandenabeele P. Caspase-containing complexes in the regulation of cell death and inflammation. Biol. Chem. 387 (2006) 1005-1016
4. Tibbetts M.D., Zheng L., and Lenardo M.J. The death effector domain protein family: regulators of cellular homeostasis. Nat. Immunol. 4 (2003) 404-409
5. Buttner S., Eisenberg T., Herker E., Carmona-Gutierrez D., Kroemer G., and Madeo F. Why yeast cells can undergo apoptosis: death in times of peace, love, and war. J. Cell Biol. 175 (2006) 521-525
6. Hamann A., Brust D., and Osiewacz H.D. Apoptosis pathways in fungal growth, development and ageing. Trends Microbiol. 16 (2008) 276-283
7. Frohlich K.U., Fussi H., and Ruckenstuhl C. Yeast apoptosis-from genes to pathways. Semin. Cancer Biol. 17 (2007) 112-121
8. Buttner S., Eisenberg T., Carmona-Gutierrez D., Ruli D., Knauer H., Ruckenstuhl C., Sigrist C., Wissing S., Kollroser M., Frohlich K.U., Sigrist S., and Madeo F. Endonuclease G regulates budding yeast life and death. Mol. Cell 25 (2007) 233-246
9. Fahrenkrog B., Sauder U., and Aebi U. The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J. Cell Sci. 117 (2004) 115-126
10. Madeo F., Herker E., Maldener C., Wissing S., Lachelt S., Herlan M., Fehr M., Lauber K., Sigrist S.J., Wesselborg S., and Frohlich K.U. A caspase-related protease regulates apoptosis in yeast. Mol. Cell 9 (2002) 911-917
11. Wissing S., Ludovico P., Herker E., Buttner S., Engelhardt S.M., Decker T., Link A., Proksch A., Rodrigues F., Corte-Real M., Frohlich K.U., Manns J., Cande C., Sigrist S.J., Kroemer G., and Madeo F. An AIF orthologue regulates apoptosis in yeast. J. Cell Biol. 166 (2004) 969-974
12. Xu Q., and Reed J.C. Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol. Cell 1 (1998) 337-346
13. Tao W., Kurschner C., and Morgan J.I. Modulation of cell death in yeast by the Bcl-2 family of proteins. J. Biol. Chem. 272 (1997) 15547-15552
14. Kang J.J., Schaber M.D., Srinivasula S.M., Alnemri E.S., Litwack G., Hall D.J., and Bjornsti M.A. Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 274 (1999) 3189-3198
15. Puryer M.A., and Hawkins C.J. Human, insect and nematode caspases kill Saccharomyces cerevisiae independently of YCA1 and Aif1p. Apoptosis 11 (2006) 509-517
16. Gietz R.D., and Woods R.A. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol. 350 (2002) 87-96
17. Eggleston M.D., and Marshall P.A. Saccharomyces cerevisiae samples stained with FUN-1 dye can be stored at - 20 degrees C for later observation. J. Microscopy 225 (2007) 100-103
18. Madeo F., Frohlich E., and Frohlich K.U. A yeast mutant showing diagnostic markers of early and late apoptosis. J. Cell Biol. 139 (1997) 729-734
19. Kaufmann S.H., Mesner Jr. P.W., Samejima K., Tone S., and Earnshaw W.C. Detection of DNA cleavage in apoptotic cells. Methods Enzymol. 322 (2000) 3-15
20. Neiman A.M. Prospore membrane formation defines a developmentally regulated branch of the secretory pathway in yeast. J. Cell Biol. 140 (1998) 29-37
21. Ng P.W., Porter A.G., and Janicke R.U. Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10. J. Biol. Chem. 274 (1999) 10301-10308
22. Scaffidi C., Medema J.P., Krammer P.H., and Peter M.E. FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. J. Biol. Chem. 272 (1997) 26953-26958
23. Eisenberg T., Buttner S., Kroemer G., and Madeo F. The mitochondrial pathway in yeast apoptosis. Apoptosis 12 (2007) 1011-1023
24. Madeo F., Frohlich E., Ligr M., Grey M., Sigrist S.J., Wolf D.H., and Frohlich K.U. Oxygen stress: a regulator of apoptosis in yeast. J. Cell Biol. 145 (1999) 757-767
25. Weinberger M., Ramachandran L., Feng L., Sharma K., Sun X., Marchetti M., Huberman J.A., and Burhans W.C. Apoptosis in budding yeast caused by defects in initiation of DNA replication. J. Cell Sci. 118 (2005) 3543-3553
26. Grallert B., and Boye E. The multiple facets of the intra-S checkpoint. Cell Cycle 7 (2008) 2315-2320
27. Gourlay C.W., and Ayscough K.R. The actin cytoskeleton: a key regulator of apoptosis and ageing?. Nature Rev. 6 (2005) 583-589
28. Leadsham J.E., and Gourlay C.W. Cytoskeletal induced apoptosis in yeast. Biochimica et biophysica acta 1783 (2008) 1406-1412
29. Zheng K., Pan J.W., Ye L., Fu Y., Peng H.Z., Wan B.Y., Gu Q., Bian H.W., Han N., Wang J.H., Kang B., Pan J.H., Shao H.H., Wang W.Z., and Zhu M.Y. Programmed cell death-involved aluminum toxicity in yeast alleviated by antiapoptotic members with decreased calcium signals. Plant physiology 143 (2007) 38-49
30. Roberts P., Moshitch-Moshkovitz S., Kvam E., O'Toole E., Winey M., and Goldfarb D.S. Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Mol. Biol. Cell 14 (2003) 129-141
31. Kroemer G., El-Deiry W.S., Golstein P., Peter M.E., Vaux D., Vandenabeele P., Zhivotovsky B., Blagosklonny M.V., Malorni W., Knight R.A., Piacentini M., Nagata S., and Melino G. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ. 12 Suppl 2 (2005) 1463-1467
32. Garrido C., and Kroemer G. Life's smile, death's grin: vital functions of apoptosis-executing proteins. Curr. Opin. Cell Biol. 16 (2004) 639-646
33. Galluzzi L., Joza N., Tasdemir E., Maiuri M.C., Hengartner M., Abrams J.M., Tavernarakis N., Penninger J., Madeo F., and Kroemer G. No death without life: vital functions of apoptotic effectors. Cell Death Differ. 15 (2008) 1113-1123
34. Kischkel F.C., Lawrence D.A., Tinel A., LeBlanc H., Virmani A., Schow P., Gazdar A., Blenis J., Arnott D., and Ashkenazi A. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J. Biol. Chem. 276 (2001) 46639-46646
35. Wang J., Chun H.J., Wong W., Spencer D.M., and Lenardo M.J. Caspase-10 is an initiator caspase in death receptor signaling. Proc. Nat. Acad. Sci. U. S. A. 98 (2001) 13884-13888
36. Gilot D., Serandour A.L., Ilyin G.P., Lagadic-Gossmann D., Loyer P., Corlu A., Coutant A., Baffet G., Peter M.E., Fardel O., and Guguen-Guillouzo C. A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes. Carcinogenesis 26 (2005) 2086-2094
37. Lee R.E., Puente L.G., Kaern M., and Megeney L.A. A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics. PLoS ONE 3 (2008) e2956
38. Bartek J., Lukas C., and Lukas J. Checking on DNA damage in S phase. Nature Rev. 5 (2004) 792-804
39. Dalle-Donne I., Rossi R., Milzani A., Di Simplicio P., and Colombo R. The actin cytoskeleton response to oxidants: from small heat shock protein phosphorylation to changes in the redox state of actin itself. Free Radic. Biol. Med> 31 (2001) 1624-1632
40. Farah M.E., and Amberg D.C. Conserved actin cysteine residues are oxidative stress sensors that can regulate cell death in yeast. Mol. Biol. Cell 18 (2007) 1359-1365
41. Staleva L., Hall A., and Orlow S.J. Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner. Mol. Biol. Cell 15 (2004) 5574-5582
42. Vilella F., Herrero E., Torres J., and de la Torre-Ruiz M.A. Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress. J. Biol. Chem. 280 (2005) 9149-9159
43. Li S.C., and Kane P.M. The yeast lysosome-like vacuole: endpoint and crossroads. Biochimica et biophysica acta (2008)
44. Mizushima N., Levine B., Cuervo A.M., and Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 451 (2008) 1069-1075
45. Khoury C.M., and Greenwood M.T. The pleiotropic effects of heterologous Bax expression in yeast. Biochimica et biophysica acta 1783 (2008) 1449-1465
46. Kissova I., Plamondon L.T., Brisson L., Priault M., Renouf V., Schaeffer J., Camougrand N., and Manon S. Evaluation of the roles of apoptosis, autophagy, and mitophagy in the loss of plating efficiency induced by Bax expression in yeast. J. Biol. Chem. 281 (2006) 36187-36197
47. Gozuacik D., and Kimchi A. Autophagy and cell death. Curr. Top. Dev. Biol. 78 (2007) 217-245
48. Scott R.C., Juhasz G., and Neufeld T.P. Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death. Curr. Biol. 17 (2007) 1-11
49. Braun R.J., and Zischka H. Mechanisms of Cdc48/VCP-mediated cell death: from yeast apoptosis to human disease. Biochimica et biophysica acta 1783 (2008) 1418-1435
50. Dudgeon D.D., Zhang N., Ositelu O.O., Kim H., and Cunningham K.W. Non-apoptotic death of Saccharomyces cerevisiae cells that is stimulated by Hsp90 and inhibited by calcineurin and Cmk2 in response to ER stresses. Eukaryotic cell (2008)