Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in livers of harbor seals (Phoca vitulina) from San Francisco Bay, California and Gulf of Maine

Marine Environmental Research

Volumn 67, Issue 3, 2009, Pages 129-135

  Park, June Soo ^a   Kalantzi, Olga Ioanna ^a   Kopec, Dianne ^b   Petreas, Myrto ^a  

^a CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF MAINE   (United States)

Author keywords

Gulf of Maine; Harbor seal liver; Hydroxylated PCB metabolites; Polychlorinated biphenyls; San Francisco Bay

Indexed keywords

BELUGA WHALES; ENDOCRINE DISRUPTORS; EXPOSURE DATUM; FOOD CHAINS; GULF OF MAINE; HARBOR SEAL LIVER; HUMAN LIVERS; HYDROXYLATED METABOLITES; HYDROXYLATED PCB METABOLITES; MARINE MAMMALS; PCB CONCENTRATIONS; PCB CONGENERS; PHOCA VITULINA; SAN FRANCISCO BAY; SAN FRANCISCO BAY , CALIFORNIA;

BIOCHEMISTRY; BIOMOLECULES; HYDROXYLATION; LIVER; MAMMALS; METABOLISM; METABOLITES; ORGANIC POLLUTANTS; PORTS AND HARBORS; PRINTED CIRCUITS;

POLYCHLORINATED BIPHENYLS;

ADULT; BIOACCUMULATION; CONCENTRATION (COMPOSITION); ENDOCRINE DISRUPTOR; FOOD CHAIN; LIPID; METABOLITE; PCB; PINNIPED; POLLUTION EXPOSURE; TOXICOLOGY; YOUNG POPULATION;

ANIMALS; CALIFORNIA; LIVER; MAINE; OCEANS AND SEAS; PHOCA; POLYCHLORINATED BIPHENYLS; WATER POLLUTANTS, CHEMICAL;

DELPHINAPTERUS LEUCAS; MAMMALIA; PHOCA; PHOCA VITULINA;

EID: 60449096165     PISSN: 01411136     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.marenvres.2008.12.003     Document Type: Article

References (48)

1. Ballschmitter K., and Zell M. Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography. Composition of technical Aroclor- and Chlophen-PCB mixtures. Fresenius′ Journal of Analytical Chemistry 302 (1980) 20-31
2. Beckmen K.B., Blake J.E., Ylitalo G.M., Stott J.L., and O'Hara T.M. Organochlorine contaminant exposure and associations with hematological and humoral immune functional assays with dam age as a factor in free-ranging northern fur seal pups (Callorhinus ursinus). Marine Pollution Bulletin 46 (2003) 594-606
3. Bergman A., Klassonwehler E., and Kuroki H. Selective retention of hydroxylated Pcb metabolites in blood. Environmental Health Perspectives 102 (1994) 464-469
4. Bigg, M. A., 1969. The harbour seal in British Columbia. Fish Res Board Canada, Bulletin 172. pp. 33.
5. Boon J.P., vanderMeer J., Allchin C.R., Law R.J., Klunsoyr J., Leonards P.E.G., Spliid H., StorrHansen E., McKenzie C., and Wells D.E. Concentration-dependent changes of PCB patterns in fish-eating mammals: Structural evidence for induction of cytochrome P450. Archives of Environmental Contamination and Toxicology 33 (1997) 298-311
6. Campbell L.M., Muir D.C.G., Whittle D.M., Backus S., Norstrom R.J., and Fisk A.T. Hydroxylated PCBs and other chlorinated phenolic compounds in lake trout (Salvelinus namaycush) blood plasma from the Great Lakes Region. Environmental Science and Technology 37 (2003) 1720-1725
7. Debier C., Chalon C., Le Boeuf B.J., de Tillesse T., Larondelle Y., and Thome J.P. Mobilization of PCBs from blubber to blood in northern elephant seals (Mirounga angustirostris) during the post-weaning fast. Aquatic Toxicology 80 (2006) 149-157
8. Fängström B., Athanasiadou M., Grandjean P., Weihe P., and Bergman A. Hydroxylated PCB metabolites and PCBs in serum from pregnant Faroese women. Environmental Health Perspectives 110 (2002) 895-899
9. Gebbink W.A., Sonne C., Dietz R., Kirkegaard M., Riget F.F., Born E.W., Muir D.C.G., and Letcher R.J. Tissue-specific congener composition of organohalogen and metabolite contaminants in East Greenland polar bears (Ursus maritimus). Environmental Pollution 152 3 (2008) 621-629
10. Guvenius D.M., Hassanzadeh P., Bergman A., and Noren K. Metabolites of polychlorinated biphenyls in human liver and adipose tissue. Environmental Toxicology and Chemistry 21 (2002) 2264-2269
11. Hall A.J., Hugunin K., Deaville R., Law R.J., Allchin C.R., and Jepson P.D. The risk of infection from polychlorinated biphenyl exposure in the harbor porpoise (Phocoena phocoena): a case-control approach. Environmental Health Perspectives 114 (2006) 704-711
12. Hammond J.A., Hall A.J., and Dyrynda E.A. Comparison of polychlorinated biphenyl (PCB) induced effects on innate immune functions in harbor and grey seals. Aquatic Toxicology 74 (2005) 126-138
13. Haraguchi K., Kato Y., Kimura R., and Masuda Y. Hydroxylation and methylthiolation of mono-ortho-substituted polychlorinated biphenyls in rats: Identification of metabolites with tissue affinity. Chemical Research in Toxicology 11 12 (1998) 1508-1515
14. Hoekstra P.F., Letcher R.J., O'Hara T.M., Backus S.M., Solomon K.R., and Muir D.C.G. Hydroxylated and methylsulfone-containing metabolites of polychlorinated biphenyls in the plasma and blubber of bowhead whales (Balaena mysticetus). Environmental Toxicology and Chemistry 22 (2003) 2650-2658
15. Houde M., Pacepavicius G., Wells R.S., Fair P.A., Letcher R.J., Alaee M., Bossart G.D., Hohn A.A., Sweeney J., Solomon K.R., and Muir D.C.G. Polychlorinated biphenyls and hydroxylated polychlorinated biphenyls in plasma of bottlenose dolphins (Tursiops truncatus) from the Western Atlantic and the Gulf of Mexico. Environmental Science and Technology 40 (2006) 5860-5866
16. Jaspers V.L.B., Dirtu A.C., Eens M., Neels H., and Covaci A. Predatory bird species show different patterns of hydroxylated polychlorinated biphenyls (HO-PCBs) and polychlorinated biphenyls (PCBs). Environmental Science and Technology 42 (2008) 3465-3471
17. Kopec, A. D., Harvey, J. T., 1995. Toxic pollutants, Health Indices and Population Dynamics of Harbor Seals in San Francisco Bay, 1989-1992. Moss Landing Marine Laboratories Technical Report 96-4, Moss Landing, CA, pp. 168 .
18. Lans M.C., Klassonwehler E., Willemsen M., Meussen E., Safe S., and Brouwer A. Structure-dependent, competitive interaction of hydroxy-polychlorobiphenyls, hydroxy-dibenzo-p-dioxins and hydroxy-dibenzofurans with human transthyretin. Chemico-Biological Interactions 88 (1993) 7-21
19. Leighty E.G., and Fentiman A.F. Conjugation of pentachlorophenol to palmitic acid by liver-microsomes. Bulletin of Environmental Contamination and Toxicology 28 (1982) 329-333
20. Letcher R.J., Klasson W.E., and Bergman A. Methylsulfon and hydroxylated metabolites of polychlorinated biphenyls. In: Paasivirta J. (Ed). Handbook of Environmental Chemistry. New Types of Persistent Halogenated Compounds vol. 3 (2000), Springer-Verlag, Berlin Part K
21. Li H.X., Boon J.P., Lewis W.E., van den Berg M., Nyman M., and Letcher R.J. Hepatic microsomal cytochrome P450 enzyme activity in relation to in vitro metabolism/inhibition of polychlorinated biphenyls and testosterone in Baltic grey seal (Halichoerus grypus). Environmental Toxicology and Chemistry 22 (2003) 636-644
22. Malmberg T., Hoogstraate J., Bergman A., and Wehler E.K. Pharmacokinetics of two major hydroxylated polychlorinated biphenyl metabolites with specific retention in rat blood. Xenobiotica 34 (2004) 581-589
23. Martineau D., Lemberger K., Dallaire A., Labelle P., Lipscomb T.P., Michel P., and Mikaelian I. Cancer in wildlife, a case study: Beluga from the St. Lawrence estuary, Quebec, Canada. Environmental Health Perspectives 110 (2002) 285-292
24. McKinney M.A., Arukwe A., De Guise S., Martineau D., Beland P., Dallaire A., Lair S., Lebeuf M., and Letcher R.J. Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (Delphinapterus leucas) from the St. Lawrence River Estuary and the Canadian Arctic. Aquatic Toxicology 69 (2004) 35-49
25. McKinney M.A., De Guise S., Martineau D., Beland P., Lebeuf M., and Letcher R.J. Organohalogen contaminants and metabolites in beluga whale (Delphinapterus leucas) liver from two Canadian populations. Environmental Toxicology and Chemistry 25 (2006) 1246-1257
26. Meerts I., Assink Y., Cenijn P.H., van den Berg J.H.J., Weijers B.M., Bergman A., Koeman J.H., and Brouwer A. Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. Toxicological Sciences 68 (2002) 361-371
27. Neale J.C.C., Gulland F.M.D., Schmelzer K.R., Harvey J.T., Berg E.A., Allen S.G., Greig D.J., Grigg E.K., and Tjeerdema R.S. Contaminant loads and hematological correlates in the harbor seal (Phoca vitulina) of San Francisco Bay, California. Journal of Toxicology and Environmental Health-Part a-Current Issues 68 (2005) 617-633
28. Neale J.C.C., Schmelzer K.R., Gulland F.M.D., Berg E.A., and Tjeerdema R.S. Rapid communication: Organohalogen levels in harbor seal (Phoca vitulina) pups increase with duration of nursing. Journal of Toxicology and Environmental Health-Part a-Current Issues 68 (2005) 687-691
29. Park J.S., Linderholm L., Charles M.J., Athanasiadou M., Petrik J., Kocan A., Drobna B., Trnovec T., Bergman A., and Hertz-Picciotto I. Polychlorinated biphenyls and their hydroxylated metabolites (OH-PCBs) in pregnant women from eastern Slovakia. Environmental Health Perspectives 115 (2007) 20-27
30. Park J.S., Petreas M., Cohn B.A., and Factor-Litvak P. Measurement of hydroxylated PCB metabolites (OH-PCBs) in archived serum from 1950-60's California mothers. Organohalogen Compounds 69 (2007) 754-757
31. Park J.S., Holden A., Wang Y., Chang J., Heckly S., McKeown K., Jewell N., and Hooper K. Hydroxylated metabolites of polychlorinated biphenyls (PCBs) in California wild birds. Organohalogen Compounds 70 (2008) 157-160
32. Reddy M.L., Reif J.S., Bachand A., and Ridgway S.H. Opportunities for using Navy marine mammals to explore associations between organochlorine contaminants and unfavorable effects on reproduction. Science of the Total Environment 274 (2001) 171-182
33. Reijnders P.J.H. Reproductive failure in common seals feeding on fish from polluted coastal waters. Nature 324 (1986) 456-457
34. Ross P.S. The role of immunotoxic environmental contaminants in facilitating the emergence of infectious diseases in marine mammals. Human and Ecological Risk Assessment 8 (2002) 277-292
35. Sandau, C. D. 2000. Analytical chemistry of hydroxylated metabolites of PCBs and other halogenated phenolic compounds in blood and their relationship to thyroid hormone and retinol homeostasis in humans and polar bears. Carleton University, Ottawa, Ontario, Canada. Ph.D. Dissertation: pp 39-44.
36. Shaw S.D., Brenner D., Bourakovsky A., Mahaffey C.A., and Perkins C.R. Polychlorinated biphenyls and chlorinated pesticides in harbor seals (Phoca vitulina concolor) from the northwestern Atlantic coast. Marine Pollution Bulletin 50 (2005) 1069-1084
37. She J.W., Petreas M., Winkler J., Visita P., McKinney M., and Kopec D. PBDEs in the San Francisco Bay Area: measurements in harbor seal blubber and human breast adipose tissue. Chemosphere 46 (2002) 697-707
38. Sormo E.G., Jussi I., Jussi M., Braathen M., Skaare J.U., and Jenssen B.M. Thyroid hormone status in gray seal (Halichoerus grypus) pups from the Baltic Sea and the Atlantic Ocean in relation to organochlorine pollutants. Environmental Toxicology and Chemistry 24 (2005) 610-616
39. Tabuchi M., Veldhoen A., Dangerfield N., Jeffries S., Helbing C.C., and Ross P.S. PCB-related alteration of thyroid hormones and thyroid hormone receptor gene expression in free-ranging Harbor seals (Phoca vitulina). Environmental Health Perspectives 114 (2006) 1024-1031
40. Teramitsu I., Yamamoto Y., Chiba I., Iwata H., Tanabe S., Fujise Y., Kazusaka A., Akahori F., and Fujita S. Identification of novel cytochrome P450 1A genes from five marine mammal species. Aquatic Toxicology 51 (2000) 145-153
41. Ueno D., Darling C., Alaee M., Campbell L., Pacepavicius G., Teixeira C., and Muir D. Detection of hydroxylated polychlorinated biphenyls (OH-PCBs) in the abiotic environment: surface water and precipitation from Ontario, Canada. Environmental Science and Technology 41 (2007) 1841-1848
42. Verreault J., Dietz R., Sonne C., Gebbink W.A., Shahmiri S., and Letcher R.J. Comparative fate of organohalogen contaminants in two top carnivores in Greenland: Captive sledge dogs and wild polar bears. Comparative Chemistry and Physiology - Toxicology and Pharmacology 147 3 (2008) 306-315
43. Verreault J., Shahmiri S., Gabrielsen G.W., and Letcher R.J. Organohalogen and metabolically-derived contaminants and associations with whole body constituents in Norwegian Arctic glaucous gulls. Environment International 33 6 (2007) 823-830
44. Wan Y., Hu J.Y., Yang M., An L.H., An W., Jin X.H., Hattori T., and Itoh M. Characterization of trophic transfer for polychlorinated dibenzo-p-dioxins, dibenzofurans, non- and mono-ortho polychlorinated biphenyls in the marine food web of Bohai Bay, north China. Environmental Science and Technology 39 (2005) 2417-2425
45. Waring G.T., Gilbert J.R., Loftin J., and Cabana N. Short-term movements of radio-tagged harbor seals in New England. Northeastern Naturalist 13 (2006) 1-14
46. Wolkers H., Hammill M.O., and van Bavel B. Tissue-specific accumulation and lactational transfer of polychlorinated biphenyls, chlorinated pesticides, and brominated flame retardants in hooded seals (Cistophora cristata) from the Gulf of St. Lawrence. Applications for monitoring. Environmental Pollution 142 3 (2006) 476-486
47. Wolkers H., Krafft B.A., van Bavel B., Helgason L.B., Lydersen C., and Kovacs K.M. Biomarker responses and decreasing contaminant levels in ringed seals (Pusa hispida) from Svalbard, Norway. Journal of Toxicology and Environmental Health: Part A 71 15 (2008) 1009-1018
48. Ylitalo G.M. The role of organochlorines in cancer-associated mortality in California sea lions (Zalophus californianus). Marine Pollution Bulletin 50 (2005) 30-39