Susceptibility to cell death induced by blockade of MAPK pathway in human colorectal cancer cells carrying Ras mutations is dependent on p53 status

Biochemical and Biophysical Research Communications

Volumn 322, Issue 2, 2004, Pages 609-613

  Wang, Zhen ^a   Li, Yuqing ^a   Liu, Edison T ^a   Yu, Qiang ^a  

^a GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

Cell death; Colon cancer; MAPK; p53; Ras

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN P53; RAS PROTEIN; 1,3 BUTADIENE DERIVATIVE; NITRILE;

ARTICLE; CANCER CELL; CELL DEATH; CELL SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; RNA INTERFERENCE; WILD TYPE; APOPTOSIS; COLORECTAL TUMOR; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; METABOLISM; PHYSIOLOGY;

APOPTOSIS; BUTADIENES; COLORECTAL NEOPLASMS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NITRILES; RAS PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 6044220227     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.07.166     Document Type: Article

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