Effects of gambogic acid on regulation of steroid receptor coactivator-3 in lung adenocarcinoma A549 cells

Chinese Journal of Cancer Research

Volumn 21, Issue 1, 2009, Pages 68-73

  Li, Rui ^a   Chen, Yan ^a   Shu, Wen Xiu ^a   Zhao, Fei ^a   Liu, Yuan ^a   Wen, Lu ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Gambogic acid; Lung cancer; SRC 3

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GAMBOGIC ACID; STEROID RECEPTOR COACTIVATOR 3;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL NUCLEUS; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENCY; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; LUNG ADENOCARCINOMA; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; WESTERN BLOTTING;

EID: 60349132305     PISSN: 10009604     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11670-009-0068-x     Document Type: Article

References (22)

1. Auterhoff H, Frauendorf H, Liesenklas W, et al. The chief constituent of gamboge resin. 1. Chemistry of gamboge [J]. Arch Pharma 1962; 295:833-846.
2. Ollis WD, Ramsay MVJ, Sutherland IO, et al. The constitution of gambogic acid [J]. Tetrahedron 1965; 21:1453-1470.
3. Zhou HJ, Yan J, Luo W, et al. SRC-3 is required for prostate cancer cell proliferation and survival [J]. Cancer Res 2005; 65: 7976-7983.
4. Zhao L, Guo QL, You QD, et al. Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells [J]. Biol Pharm Bull 2004; 27:998-1003.
5. Guo QL, Lin SS, You QD, et al. Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells [J]. Life Sci 2006; 78: 1238-1245.
6. Wang Y, Chen Y, Chen Z, et al. Gambogic acid induces death inducer-obliterator 1-mediated apoptosis in Jurkat T cells [J]. Acta Pharmacol Sin 2008; 29:349-354.
7. Anzick SL, Kononen J, Walker RL, et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer [J]. Science 1997; 277:965-968.
8. Han SJ, Demayo FJ, Xu J, et al. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor [J]. Mol Endocrinol 2006; 20: 45-55.
9. Ying H, Furuya F, Willingham MC, et al. Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone [J]. Mol Cell Biol 2005; 25:7687-7695.
10. Lee SK, Kim HJ, Na SY, et al. Steroid receptor coactivator-1 coactivates activating protein-1-mediated transactivations through interaction with the c-Jun and c-Fos subunits [J]. J Biol Chem 1998; 273:16651-16654.
11. Werbajh S, Nojek I, Lanz R, et al. RAC-3 is a NF-kappa B coactivator [J]. FEBS Lett 2000; 485:195-199.
12. Chen D, Ma H, Hong H, et al. Regulation of transcription by a protein methyltransferase [J]. Science 1999; 284:2174-2177.
13. McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators [J]. Cell 2002; 108:465-474.
14. Kuang SQ, Liao L, Zhang H, et al. AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-rasinduced breast cancer initiation and progression in mice [J]. Cancer Res 2004; 64:1875-1885.
15. Tanner MM, Grenman S, Koul A, et al. Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer [J]. Clin Cancer Res 2000; 6:1833-1839.
16. Henke RT, Haddad BR, Kim SE, et al. Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma [J]. Clin Cancer Res 2004; 10:6134-6142.
17. Ghadimi BM, Schröck E, Walker RL, et al. Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas [J]. Am J Pathol 1999; 154:525-536.
18. Sakakura C, Hagiwara A, Yasuoka R, et al. Amplification and over-expression of the AIB1 nuclear receptor co-activator gene in primary gastric cancers [J]. Int J Cancer 2000; 89:217-223.
19. Wang Y, Wu MC, Sham JS, et al. Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray [J]. Cancer 2002; 95:2346-2352.
20. Torres-Arzayus MI, Font de Mora J, Yuan J, et al. High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene [J]. Cancer Cell 2004; 6:263-74.
21. Márquez-Garbán DC, Chen HW, Fishbein MC, et al. Estrogen receptor signaling pathways in human non-small cell lung cancer[J]. Steroids 2007; 72:135-143.
22. Lahusen T, Fereshteh M, Oh A, et al. Epidermal growth factor receptor tyrosine phosphorylation and signaling controlled by a nuclear receptor coactivator, amplified in breast cancer 1 [J]. Cancer Res 2007; 67: 7256-7265.