Differential induction of cytochrome P450 1A1 and 1B1 mRNA in primary cultured bovine hepatocytes treated with TCDD, PBDD/Fs and feed ingredients

Toxicology Letters

Volumn 185, Issue 3, 2009, Pages 193-196

  Guruge, Keerthi S ^a   Yamanaka, Noriko ^a   Hasegawa, Jun ^a   Miyazaki, Shigeru ^a  

^a NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

Author keywords

Brominated dioxins; Cytochrome; Hepatocytes; Real time RT PCR; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; FISH OIL; MESSENGER RNA; POLYBROMINATED DIBENZODIOXIN; POLYBROMINATED DIBENZOFURAN;

ANIMAL CELL; ANIMAL FOOD; ARTICLE; CALF (BOVINE); CONTROLLED STUDY; ENZYME ANALYSIS; LIVER CELL CULTURE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS;

ANIMAL FEED; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZOFURANS; CATTLE; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FISH OILS; HEPATOCYTES; HYDROCARBONS, BROMINATED; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN;

ANIMALIA; BOVINAE;

EID: 60349097752     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.01.002     Document Type: Article

References (26)

1. Abel J., Li W., Döhr O., Vogel C., and Donat S. Dose-response relationship of cytochrome P4501b1 mRNA induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in livers of C57BL/6J and DBA/2J mice. Arch. Toxicol. 70 (1996) 510-513
2. Behnisch P.A., Hosoe K., and Sakai S. Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. Environ. Int. 29 (2003) 861-877
3. Denison M.S., and Whitlock Jr. J.P. Xenobiotic-inducible transcription of cytochrome P450 genes. J. Biol. Chem. 270 (1995) 18175-18178 (Minireview)
4. Denison M., and Nagy S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43 (2003) 309-334 (Review)
5. Gebhardt R., Hengstler J.G., Müller D., Glöckner R., Buenning P., Laube B., Schmelzer E., Ullrich M., Utesch D., Hewitt N., Ringel M., Hilz B.R., Bader A., Langsch A., Koose T., Burger H.J., Maas J., and Oesch F. New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metab. Rev. 35 (2003) 145-213
6. Gilbertson M., Kubiak T., Ludwig J., and Fox G. Great Lakes embryo mortality, edema, and deformities syndrome (GLEMEDS) in colonial fish-eating birds: similarity to chick-edema disease. J. Toxicol. Environ. Health 33 (1991) 455-520
7. Guruge K.S., Yamanaka N., Kubota T., Miyazaki S., and Motoi Y. Identification of CYP1A1 gene expression and ethoxyresorufin-O-deethylase (EROD) activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in primary cultured bovine hepatocytes. Organohalogen Compd. 53 (2001) 251-254
8. Hasegawa J., Guruge K.S., Seike N., Shirai Y., Yamata T., Nakamura M., Handa H., Yamanaka N., and Miyazaki S. Determination of PCDD/Fs and dioxin-like PCBs in fish oils for feed ingredients by congener-specific chemical analysis and CALUX bioassay. Chemosphere 69 (2007) 1188-1194
9. Haws L.C., Su S.H., Harris M., Devito M.J., Walker N.J., Farland W.H., Finley B., and Birnbaum L.S. Development of a refined database of mammalian relative potency estimates for dioxin-like compounds. Toxicol. Sci. 89 (2006) 4-30
10. Higuchi H., Katoh N., Miyamoto T., Uchida E., Yuasa A., and Takahashi K. Dexamethasone-induced haptoglobin release by calf liver parenchymal cells. Am. J. Vet. Res. 55 (1994) 1080-1085
11. Kennedy S.W., Lorenzen A., Jones S.P., Hahn M.E., and Stegeman J.J. Cytochrome P4501A induction in avian hepatocyte cultures: a promising approach for predicting the sensitivity of avian species to toxic effects of halogenated aromatic hydrocarbons. Toxicol. Appl. Pharmacol. 141 (1996) 214-230
12. MAFF (Ministry of Agriculture, Forestry and Fisheries) of Japan, 2004. The provisional guidelines for analytical method of dioxin-related compounds in feed (in Japanease).
13. Martineau D., De Guise S., Fournier M., Shugart L., Girard C., Lagacé A., and Béland P. Pathology and toxicology of beluga whales from the St. Lawrence Estuary, Quebec, Canada. Past, present and future. Sci. Total. Environ. 154 (1994) 201-215
14. Nelson D.R., Koymans L., Kamataki T., Stegeman J.J., Feyereisen R., Waxman D.J., Waterman M.R., Gotoh O., Coon M.J., Estabrook R.W., Gunsalus I.C., and Nebert D.W. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6 (1996) 1-42
15. Olsman H., Engwall M., Kammann U., Klempt M., Otte J., Bavel B., and Hollert H. Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species. Environ. Toxicol. Chem. 26 (2007) 2448-2454
16. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
17. Poland A., and Knutson J.C. 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22 (1982) 517-554
18. Safe S.H. Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans. Annu. Rev. Pharmacol. Toxicol. 26 (1986) 371-399
19. Seglen P.O. Preparation rat liver cells. III. Enzymatic requirement for tissue dispersion. Exp. Cell Res. 82 (1973) 391-398
20. Silkworth J.B., Koganti A., Illouz K., Possolo A., Zhao M., and Hamilton S.B. Comparison of TCDD and PCB CYP1A induction sensitivities in fresh hepatocytes from human donors, sprague-dawley rats, and rhesus monkeys and HepG2 cells. Toxicol. Sci. 87 (2005) 508-519
21. Smeets J.M., van Holsteijn I., Giesy J.P., and van den Berg M. The anti-estrogenicity of Ah receptor agonists in carp (Cyprinus carpio) hepatocytes. Toxicol. Sci. 52 (1999) 178-188
22. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., Fiedler H., Hakansson H., Hanberg A., Haws L., Rose M., Safe S., Schrenk D., Tohyama C., Tritscher A., Tuomisto J., Tysklind M., Walker N., and Peterson R.E. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol. Sci. 93 (2006) 223-241
23. Walker N.J., Portier C.J., Lax S.F., Crofts F.G., Li Y., Lucier G.W., and Sutter T.R. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 154 (1999) 279-286
24. Wang K., Shindoh H., Inoue T., and Horii I. Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines. J. Toxicol. Sci. 27 (2002) 229-237
25. Wilson C.L., and Safe S. Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses. Toxicol. Pathol. 26 (1998) 657-671 (Review)
26. Xu L., Li A.P., Kaminski D.L., and Ruh M.F. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in cultured rat and human hepatocytes. Chem. Biol. Interact. 124 (2000) 173-189