Lipid metabolism predicts changes in body composition during energy restriction in overweight humans

Journal of Nutrition

Volumn 139, Issue 2, 2009, Pages 222-229

  Smilowitz, Jennifer T ^a   Wiest, Michelle M ^b   Watkins, Steven M ^c   Teegarden, Dorothy ^d   Zemel, Michael B ^e   German, J Bruce ^a   Van Loan, Marta D ^f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF IDAHO   (United States)

^c Lipomics Technologies Inc   (United States)

^d PURDUE UNIVERSITY   (United States)

^e UNIVERSITY OF TENNESSEE   (United States)

^f AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; LIPID; PHOSPHATIDYLCHOLINE;

ADIPOSE TISSUE; ADULT; ANTHROPOMETRY; ARTICLE; BODY COMPOSITION; BODY FAT; BODY WEIGHT; CALORIC RESTRICTION; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FEMALE; HUMAN; LEAN BODY WEIGHT; LIPID METABOLISM; MALE; METABOLITE; OBESITY; QUANTITATIVE ANALYSIS; WAIST CIRCUMFERENCE; WEIGHT REDUCTION; BLOOD; CHEMISTRY; METABOLISM; PATHOLOGY;

BODY COMPOSITION; CALORIC RESTRICTION; COHORT STUDIES; FATTY ACIDS; HUMANS; LIPID METABOLISM; LIPIDS; OVERWEIGHT; WEIGHT LOSS;

EID: 60249093081     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.108.095364     Document Type: Article

References (34)

1. Bray GA, Champagne CM. Beyond energy balance: there is more to obesity than kilocalories. J Am Diet Assoc. 2005;105:S17-23.
2. NIH. Technology Assessment Conference Statement: methods for voluntary weight loss and control, March 30-April 1, 1992. Nutr Rev. 1992;50:340-5.
3. Villareal DT, Fontana L, Weiss EP, Racette SB, Steger-May K, Schechtman KB, Klein S, Holloszy JO. Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial. Arch Intern Med. 2006;166:2502-10.
4. Weiss EP, Racette SB, Villareal DT, Fontana L, Steger-May K, Schechtman KB, Klein S, Ehsani AA, Holloszy JO. Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss. J Appl Physiol. 2007;102:634-40.
5. German JB, Roberts MA, Watkins SM. Personal metabolomics as a next generation nutritional assessment. J Nutr. 2003;133:4260-6.
6. German JB, Gillies LA, Smilowitz JT, Zivkovic AM, Watkins SM. Lipidomics and lipid profiling in metabolomics. Curr Opin Lipidol. 2007;18:66-71.
7. German JB, Hammock BD, Watkins SM. Metabolomics: building on a century of biochemistry to guide human health. Metabolomics. 2005; 1:3-9.
8. Cazeils JL, Bouillier-Oudot M, Auvergne A, Candau M, Babile R. Lipid composition of hepatocyte plasma membranes from geese overfed with corn. Lipids. 1999;34:937-42.
9. Fukuchi S, Hamaguchi K, Seike M, Himeno K, Sakata T, Yoshimatsu H. Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats. Exp Biol Med (Maywood). 2004;229:486-93.
10. Houdali B, Wahl HG, Kresi M, Nguyen V, Haap M, Machicao F, Ammon HP, Renn W, Schleicher ED, et al. Glucose oversupply increases Delta9-desaturase expression and its metabolites in rat skeletal muscle. Diabetologia. 2003;46:203-12.
11. Ntambi JM, Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res. 2004;43:91-104.
12. Kim YC, Gomez FE, Fox BG, Ntambi JM. Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipo-cytes. J Lipid Res. 2000;41:1310-6.
13. Waters KM, Miller CW, Ntambi JM. Localization of a negative thyroid hormone-response region in hepatic stearoyl-CoA desaturase gene 1. Biochem Biophys Res Commun. 1997;233:838-43.
14. Waters KM, Ntambi JM. Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression of diabetic mice. J Biol Chem. 1994; 269:27773-7.
15. Kis M, Zsiros O, Farkas T, Wada H, Nagy F, Gombos Z. Light-induced expression of fatty acid desaturase genes. Proc Natl Acad Sci USA. 1998;95:4209-14.
16. Listenberger LL, Han X, Lewis SE, Cases S, Farese RV Jr, Ory DS, Schaffer JE. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci USA. 2003;100:3077-82.
17. Lee Y, Naseem RH, Duplomb L, Park BH, Garry DJ, Richardson JA, Schaffer JE, Unger RH. Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Proc Natl Acad Sci USA. 2004;101:13624-9.
18. Salomaa V, Ahola I, Tuomilehto J, Aro A, Pietinen P, Korhonen HJ, Penttila I. Fatty acid composition of serum cholesterol esters in different degrees of glucose intolerance: a population-based study. Metabolism. 1990;39:1285-91.
19. Hodge AM, English DR, O'Dea K, Sinclair AJ, Makrides M, Gibson RA, Giles GG. Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: interpreting the role of linoleic acid. Am J Clin Nutr. 2007;86:189-97.
20. Wang L, Folsom AR, Zheng ZJ, Pankow JS, Eckfeldt JH. Plasma fatty acid composition and incidence of diabetes in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Clin Nutr. 2003;78:91-8.
21. Zemel MB, Teegarden D, Van Loan M, Schoeller DA, Matkovic V, Lyle RM, Craig BA. Role of dairy products in modulating weight and fat loss: a multi-center trial. FASEB J. 2004;18:A845.
22. Teegarden D, White KM, Lyle RM, Zemel MB, Van Loan MD, Matkovic V, Craig BA, Schoeller DA. Calcium and dairy product modulation of lipid utilization and energy expenditure. Obesity (Silver-Spring). 2008;16(7):1566-72.
23. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz A, Strath SJ, O'Brien WL, Bassett DR Jr, Schmitz KH, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000;32:S498-504.
24. Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care. 2004;27:1487-95.
25. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957;226:497-509.
26. Watkins SM, Lin TY, Davis RM, Ching JR, DePeters EJ, Halpern GM, Walzem RL, German JB. Unique phospholipid metabolism in mouse heart in response to dietary docosahexaenoic or alpha-linolenic acids. Lipids. 2001;36:247-54.
27. Wang Y, Botolin D, Xu J, Christian B, Mitchell E, Jayaprakasam B, Nair MG, Peters JM, Busik JV, et al. Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity. J Lipid Res. 2006;47: 2028-41.
28. Mougios V, Kotzamanidis C, Koutsari C, Atsopardis S. Exercise-induced changes in the concentration of individual fatty acids and triacylglycerols of human plasma. Metabolism. 1995;44:681-8.
29. Jang Y, Kim OY, Lee JH, Koh SJ, Chae JS, Kim JY, Park S, Cho H, Lee JE, et al. Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss. Int J Obes (Lond). 2006;30:1601-8.
30. Mottagui-Tabar S, Ryden M, Lofgren P, Faulds G, Hoffstedt J, Brookes AJ, Andersson I, Arner P. Evidence for an important role of perilipin in the regulation of human adipocyte lipolysis. Diabetologia. 2003;46: 789-97.
31. Boden G, Shulman GI. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest. 2002;32 Suppl 3:14-23.
32. Brehm A, Krssak M, Schmid Al, Nowotny P, Waldhausl W, Roden M. Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes. 2006;55:136-40.
33. Watkins SM, Zhu X, Zeisel SH. Phosphatidylethanolamine-N- methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. J Nutr. 2003;133: 3386-91.
34. Hartz CS, Nieman KM, Jacobs RL, Vance DE, Schalinske KL. Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic rats. J Nutr. 2006;136:3005-9.