Underlying mechanism of actions of tefluthrin, a pyrethroid insecticide, on voltage-gated ion currents and on action currents in pituitary tumor (GH3) cells and GnRH-secreting (GT1-7) neurons

Toxicology

Volumn 258, Issue 1, 2009, Pages 70-77

  Wu, Sheng Nan ^a   Wu, Yung Han ^a   Chen, Bing Shuo ^a,b   Lo, Yi Ching ^c   Liu, Yen Chin ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Action current; GH3 cells; GT1 7 cells; L type Ca2+ current; Na+ current; Pyrethroid; Tefluthrin

Indexed keywords

CALCIUM CHANNEL L TYPE; GONADORELIN; INSECTICIDE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; POTASSIUM; PYRETHROID; RANOLAZINE; RILUZOLE; TEFLUTHRIN; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRAIN NERVE CELL; CELL ADHESION; CELL STRAIN GH3; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ENDOCRINE FUNCTION; HYPOPHYSIS TUMOR; HYPOTHALAMUS; IN VIVO STUDY; ION CURRENT; NEUROENDOCRINE SYSTEM; NONHUMAN; OSCILLATION; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; RECORDING; TUMOR CELL; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS, L-TYPE; CELL LINE, TUMOR; CYCLOPROPANES; GONADOTROPIN-RELEASING HORMONE; HYDROCARBONS, FLUORINATED; INSECTICIDES; ION CHANNEL GATING; NEURONS; PATCH-CLAMP TECHNIQUES; PITUITARY NEOPLASMS; POTASSIUM CHANNELS; RATS; SODIUM CHANNELS;

EID: 60249088334     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.01.009     Document Type: Article

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