메뉴 건너뛰기




Volumn 98, Issue 1, 2007, Pages 131-144

Mechanism of spontaneous and receptor-controlled electrical activity in pituitary somatotrophs: Experiments and theory

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; GROWTH HORMONE RELEASING FACTOR; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SOMATOSTATIN; TETRODOTOXIN; VOLTAGE GATED CALCIUM CHANNEL;

EID: 34447571654     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00872.2006     Document Type: Article
Times cited : (83)

References (62)
  • 1
    • 0038675292 scopus 로고    scopus 로고
    • Nitric oxide inhibits prolactin secretion in pituitary cells downstream of voltage-gated calcium influx
    • Andric SA, Gonzalez-Iglesias AE, Van Goor F, Tomic M, Stojilkovic SS. Nitric oxide inhibits prolactin secretion in pituitary cells downstream of voltage-gated calcium influx. Endocrinology 144: 2912-2921, 2003.
    • (2003) Endocrinology , vol.144 , pp. 2912-2921
    • Andric, S.A.1    Gonzalez-Iglesias, A.E.2    Van Goor, F.3    Tomic, M.4    Stojilkovic, S.S.5
  • 2
    • 0020593740 scopus 로고
    • Stimulation of adenosine 3′,5′-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro
    • Bilezikjian LM, Vale WW. Stimulation of adenosine 3′,5′-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro. Endocrinology 113: 1726-1731, 1983.
    • (1983) Endocrinology , vol.113 , pp. 1726-1731
    • Bilezikjian, L.M.1    Vale, W.W.2
  • 3
    • 0022978198 scopus 로고
    • + channel in the bursting pancreatic beta-cell
    • + channel in the bursting pancreatic beta-cell. Biophys J 50: 765-777, 1986.
    • (1986) Biophys J , vol.50 , pp. 765-777
    • Chay, T.R.1
  • 4
    • 0020957719 scopus 로고
    • Minimal model for membrane oscillations in the pancreatic beta-cell
    • Chay TR, Keizer J. Minimal model for membrane oscillations in the pancreatic beta-cell. Biophys J 42: 181-190, 1983.
    • (1983) Biophys J , vol.42 , pp. 181-190
    • Chay, T.R.1    Keizer, J.2
  • 5
    • 0028940815 scopus 로고
    • 2+ influx in the ovine somatotroph by growth hormone-releasing factor
    • 2+ influx in the ovine somatotroph by growth hormone-releasing factor. Am J Physiol Endocrinol Metab 268: E204-212, 1995.
    • (1995) Am J Physiol Endocrinol Metab , vol.268
    • Chen, C.1    Clarke, I.J.2
  • 6
    • 0025319034 scopus 로고
    • Sodium and calcium currents in action potentials of rat somatotrophs: Their possible functions in growth hormone secretion
    • Chen C, Zhang J, Vincent JD, Israel JM. Sodium and calcium currents in action potentials of rat somatotrophs: their possible functions in growth hormone secretion. Life Sci 46: 983-989, 1990a.
    • (1990) Life Sci , vol.46 , pp. 983-989
    • Chen, C.1    Zhang, J.2    Vincent, J.D.3    Israel, J.M.4
  • 7
    • 0025676399 scopus 로고
    • Somatostatin increases voltage-dependent potassium currents in rat somatotrophs
    • Chen C, Zhang J, Vincent JD, Israel JM. Somatostatin increases voltage-dependent potassium currents in rat somatotrophs. Am J Physiol Cell Physiol 259: C854-861, 1990b.
    • (1990) Am J Physiol Cell Physiol , vol.259
    • Chen, C.1    Zhang, J.2    Vincent, J.D.3    Israel, J.M.4
  • 8
    • 15244361042 scopus 로고    scopus 로고
    • Regulation of recombinant and native hyperpolarization-activated cation channels
    • Frere SG, Kuisle M, Luthi A. Regulation of recombinant and native hyperpolarization-activated cation channels. Mol Neurobiol 30: 279-305, 2004.
    • (2004) Mol Neurobiol , vol.30 , pp. 279-305
    • Frere, S.G.1    Kuisle, M.2    Luthi, A.3
  • 10
    • 33745206357 scopus 로고    scopus 로고
    • Dependence of electrical activity and calcium influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs
    • Gonzalez-Iglesias AE, Jiang Y, Tomic M, Kretschmannova K, Andric SA, Zemkova H, Stojilkovic SS. Dependence of electrical activity and calcium influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs. Mol Endocrinol 20: 2231-2246, 2006a.
    • (2006) Mol Endocrinol , vol.20 , pp. 2231-2246
    • Gonzalez-Iglesias, A.E.1    Jiang, Y.2    Tomic, M.3    Kretschmannova, K.4    Andric, S.A.5    Zemkova, H.6    Stojilkovic, S.S.7
  • 11
    • 33745188446 scopus 로고    scopus 로고
    • ZD7288 inhibits exocytosis in an HCN-independent manner and downstream of voltage-gated calcium influx in pituitary lactotrophs
    • Gonzalez-Iglesias AE, Kretschmannova K, Tomic M, Stojilkovic SS. ZD7288 inhibits exocytosis in an HCN-independent manner and downstream of voltage-gated calcium influx in pituitary lactotrophs. Biochem Biophys Res Commun 346: 845-850, 2006b.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 845-850
    • Gonzalez-Iglesias, A.E.1    Kretschmannova, K.2    Tomic, M.3    Stojilkovic, S.S.4
  • 13
    • 0023920443 scopus 로고
    • Intracellular calcium concentration and growth hormone secretion in individual somatotropes: Effects of xgrowth hormone-releasing factor and somatostatin
    • Holl RW, Thorner MO, Leong DA. Intracellular calcium concentration and growth hormone secretion in individual somatotropes: effects of xgrowth hormone-releasing factor and somatostatin. Endocrinology 122: 2927-2932, 1988.
    • (1988) Endocrinology , vol.122 , pp. 2927-2932
    • Holl, R.W.1    Thorner, M.O.2    Leong, D.A.3
  • 14
    • 0000303940 scopus 로고    scopus 로고
    • Neural excitability, spiking, and bursting
    • Izhikevich EM. Neural excitability, spiking, and bursting. Int J Bifurcation Chaos 10: 1171-1266, 2000.
    • (2000) Int J Bifurcation Chaos , vol.10 , pp. 1171-1266
    • Izhikevich, E.M.1
  • 15
    • 0028317927 scopus 로고
    • 2+] with fluorescent indicators
    • 2+] with fluorescent indicators. Methods Cell Biol 40: 155-181, 1994.
    • (1994) Methods Cell Biol , vol.40 , pp. 155-181
    • Kao, J.P.1
  • 16
    • 0028868898 scopus 로고
    • 2+ current in primary cultured rat somatotrophs
    • 2+ current in primary cultured rat somatotrophs. J Neuroendocrinol 7: 855-859, 1995.
    • (1995) J Neuroendocrinol , vol.7 , pp. 855-859
    • Kato, M.1
  • 17
    • 0026576828 scopus 로고
    • Imaging of intracellular calcium in rat anterior pituitary cells in response to growth hormone releasing factor
    • Kato M, Hoyland J, Sikdar SK, Mason WT. Imaging of intracellular calcium in rat anterior pituitary cells in response to growth hormone releasing factor. J Physiol 447: 171-189, 1992.
    • (1992) J Physiol , vol.447 , pp. 171-189
    • Kato, M.1    Hoyland, J.2    Sikdar, S.K.3    Mason, W.T.4
  • 18
    • 0030670069 scopus 로고    scopus 로고
    • + current in the primary cultured rat somatotroph
    • + current in the primary cultured rat somatotroph. Endocrinology 138: 5096-5100, 1997.
    • (1997) Endocrinology , vol.138 , pp. 5096-5100
    • Kato, M.1    Sakuma, Y.2
  • 19
    • 0036301043 scopus 로고    scopus 로고
    • Cyclic nucleotide-gated ion channels
    • Kaupp UB, Seifert R. Cyclic nucleotide-gated ion channels. Physiol Rev 82: 769-824, 2002.
    • (2002) Physiol Rev , vol.82 , pp. 769-824
    • Kaupp, U.B.1    Seifert, R.2
  • 20
    • 0032230275 scopus 로고    scopus 로고
    • Functional role of alternative splicing in pituitary P2X2 receptor-channel activation and desensitization
    • Koshimizu T, Tomic M, Van Goor F, Stojilkovic SS. Functional role of alternative splicing in pituitary P2X2 receptor-channel activation and desensitization. Mol Endocrinol 12: 901-913, 1998.
    • (1998) Mol Endocrinol , vol.12 , pp. 901-913
    • Koshimizu, T.1    Tomic, M.2    Van Goor, F.3    Stojilkovic, S.S.4
  • 21
    • 0033711098 scopus 로고    scopus 로고
    • Characterization of purinergic receptors and receptor-channels expressed in anterior pituitary cells
    • Koshimizu TA, Tomic M, Wong AO, Zivadinovic D, Stojilkovic SS. Characterization of purinergic receptors and receptor-channels expressed in anterior pituitary cells. Endocrinology 141: 4091-4099, 2000.
    • (2000) Endocrinology , vol.141 , pp. 4091-4099
    • Koshimizu, T.A.1    Tomic, M.2    Wong, A.O.3    Zivadinovic, D.4    Stojilkovic, S.S.5
  • 22
    • 0842334077 scopus 로고    scopus 로고
    • Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5′-monophosphate production in pituitary cells
    • Kostic TS, Andric SA, Stojilkovic SS. Receptor-controlled phosphorylation of alpha 1 soluble guanylyl cyclase enhances nitric oxide-dependent cyclic guanosine 5′-monophosphate production in pituitary cells. Mol Endocrinol 18: 458-470, 2004.
    • (2004) Mol Endocrinol , vol.18 , pp. 458-470
    • Kostic, T.S.1    Andric, S.A.2    Stojilkovic, S.S.3
  • 23
    • 0037053379 scopus 로고    scopus 로고
    • Calcium-independent and cAMP-dependent modulation of soluble guanylyl cyclase activity by G protein-coupled receptors in pituitary cells
    • Kostic TS, Tomic M, Andric SA, Stojilkovic SS. Calcium-independent and cAMP-dependent modulation of soluble guanylyl cyclase activity by G protein-coupled receptors in pituitary cells. J Biol Chem 277: 16412-16418, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 16412-16418
    • Kostic, T.S.1    Tomic, M.2    Andric, S.A.3    Stojilkovic, S.S.4
  • 24
    • 33744762807 scopus 로고    scopus 로고
    • Dependence of hyperpolarisation-activated cyclic nucleotide-gated channel activity on basal cyclic adenosine monophosphate production in spontaneously firing GH3 cells
    • Kretschmannova K, Gonzalez-Iglesias AE, Tomic M, Stojilkovic SS. Dependence of hyperpolarisation-activated cyclic nucleotide-gated channel activity on basal cyclic adenosine monophosphate production in spontaneously firing GH3 cells. J Neuroendocrinol 18: 484-493, 2006.
    • (2006) J Neuroendocrinol , vol.18 , pp. 484-493
    • Kretschmannova, K.1    Gonzalez-Iglesias, A.E.2    Tomic, M.3    Stojilkovic, S.S.4
  • 25
    • 0030797192 scopus 로고    scopus 로고
    • Corticotropin releasing hormone inhibits an inwardly rectifying potassium current in rat corticotropes
    • Kuryshev YA, Haak L, Childs GV, Ritchie AK. Corticotropin releasing hormone inhibits an inwardly rectifying potassium current in rat corticotropes. J Physiol 502: 265-279, 1997.
    • (1997) J Physiol , vol.502 , pp. 265-279
    • Kuryshev, Y.A.1    Haak, L.2    Childs, G.V.3    Ritchie, A.K.4
  • 26
    • 0031595936 scopus 로고    scopus 로고
    • 2+ oscillations by anterior pituitary cells: A comparative overview
    • 2+ oscillations by anterior pituitary cells: a comparative overview. Neuroendocrinology 68: 135-151, 1998.
    • (1998) Neuroendocrinology , vol.68 , pp. 135-151
    • Kwiecien, R.1    Hammond, C.2
  • 29
    • 0344305676 scopus 로고    scopus 로고
    • Role of K(+) channels in frequency regulation of spontaneous action potentials in rat pituitary GH(3) cells
    • Lee SH, Lee EH, Ryu SY, Rhim H, Baek HJ, Lim W, Ho WK. Role of K(+) channels in frequency regulation of spontaneous action potentials in rat pituitary GH(3) cells. Neuroendocrinology 78: 260-269, 2003.
    • (2003) Neuroendocrinology , vol.78 , pp. 260-269
    • Lee, S.H.1    Lee, E.H.2    Ryu, S.Y.3    Rhim, H.4    Baek, H.J.5    Lim, W.6    Ho, W.K.7
  • 30
    • 0023735194 scopus 로고
    • Calcium currents and fura-2 signals in fluorescence-activated cell sorted lactotrophs and somatotrophs of rat anterior pituitary
    • Lewis DL, Goodman MB, St John PA, Barker JL. Calcium currents and fura-2 signals in fluorescence-activated cell sorted lactotrophs and somatotrophs of rat anterior pituitary. Endocrinology 123: 611-621, 1988.
    • (1988) Endocrinology , vol.123 , pp. 611-621
    • Lewis, D.L.1    Goodman, M.B.2    St John, P.A.3    Barker, J.L.4
  • 31
    • 0022858916 scopus 로고
    • A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line
    • Lewis DL, Weight FF, Luini A. A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line. Proc Natl Acad Sci USA 83: 9035-9039, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 9035-9039
    • Lewis, D.L.1    Weight, F.F.2    Luini, A.3
  • 32
    • 0023000028 scopus 로고
    • Somatostatin, an inhibitor of ACTH secretion, decreases cytosolic free calcium and voltage-dependent calcium current in a pituitary cell line
    • Luini A, Lewis D, Guild S, Schofield G, Weight F. Somatostatin, an inhibitor of ACTH secretion, decreases cytosolic free calcium and voltage-dependent calcium current in a pituitary cell line. J Neurosci 6: 3128-3132, 1986.
    • (1986) J Neurosci , vol.6 , pp. 3128-3132
    • Luini, A.1    Lewis, D.2    Guild, S.3    Schofield, G.4    Weight, F.5
  • 33
    • 0025924620 scopus 로고
    • 2+ concentration and growth hormone (GH) release from purified rat somatotrophs. III. Mechanism of action of GH-releasing factor and somatostatin
    • 2+ concentration and growth hormone (GH) release from purified rat somatotrophs. III. Mechanism of action of GH-releasing factor and somatostatin. Endocrinology 128: 592-603, 1991.
    • (1991) Endocrinology , vol.128 , pp. 592-603
    • Lussier, B.T.1    French, M.B.2    Moor, B.C.3    Kraicer, J.4
  • 34
    • 0023795123 scopus 로고
    • Whole-cell recordings of ionic currents in bovine somatotrophs and their involvement in growth hormone secretion
    • Mason WT, Rawlings SR. Whole-cell recordings of ionic currents in bovine somatotrophs and their involvement in growth hormone secretion. J Physiol 405: 577-593, 1988.
    • (1988) J Physiol , vol.405 , pp. 577-593
    • Mason, W.T.1    Rawlings, S.R.2
  • 36
    • 0028308801 scopus 로고
    • Actions of growth-hormone- releasing hormone on rat pituitary cells: Intracellular calcium and ionic currents
    • Naumov AP, Herrington J, Hille B. Actions of growth-hormone- releasing hormone on rat pituitary cells: intracellular calcium and ionic currents. Pfluegers 427: 414-421, 1994.
    • (1994) Pfluegers , vol.427 , pp. 414-421
    • Naumov, A.P.1    Herrington, J.2    Hille, B.3
  • 37
    • 0022559209 scopus 로고
    • Somatostatin mediation of adenohypophysial secretion
    • Patel YC, Srikant CB. Somatostatin mediation of adenohypophysial secretion. Annu Rev Physiol 48: 551-567, 1986.
    • (1986) Annu Rev Physiol , vol.48 , pp. 551-567
    • Patel, Y.C.1    Srikant, C.B.2
  • 38
    • 0033949993 scopus 로고    scopus 로고
    • Somatostatin-induced control of cytosolic free calcium in pituitary tumour cells
    • Petrucci C, Cervia D, Buzzi M, Biondi C, Bagnoli P. Somatostatin-induced control of cytosolic free calcium in pituitary tumour cells. Br J Pharmacol 129: 471-484, 2000.
    • (2000) Br J Pharmacol , vol.129 , pp. 471-484
    • Petrucci, C.1    Cervia, D.2    Buzzi, M.3    Biondi, C.4    Bagnoli, P.5
  • 39
    • 0033821712 scopus 로고    scopus 로고
    • Activation of BK channels in rat chromaffin cells requires summation of Ca(2+) influx from multiple Ca(2+) channels
    • Prakriya M, Lingle CJ. Activation of BK channels in rat chromaffin cells requires summation of Ca(2+) influx from multiple Ca(2+) channels. J Neurophysiol 84: 1123-1135, 2000.
    • (2000) J Neurophysiol , vol.84 , pp. 1123-1135
    • Prakriya, M.1    Lingle, C.J.2
  • 40
    • 0032526920 scopus 로고    scopus 로고
    • Simulation study of cellular electric properties in heart failure
    • Priebe L, Beuckelmann DJ. Simulation study of cellular electric properties in heart failure. Circ Res 82: 1206-1223, 1998.
    • (1998) Circ Res , vol.82 , pp. 1206-1223
    • Priebe, L.1    Beuckelmann, D.J.2
  • 41
    • 0025775356 scopus 로고
    • Low access resistance perforated patch recordings using amphotericin B
    • Rae J, Cooper K, Gates P, Watsky M. Low access resistance perforated patch recordings using amphotericin B. J Neurosci Methods 37: 15-26, 1991.
    • (1991) J Neurosci Methods , vol.37 , pp. 15-26
    • Rae, J.1    Cooper, K.2    Gates, P.3    Watsky, M.4
  • 42
    • 0030452374 scopus 로고    scopus 로고
    • A role for a background sodium current in spontaneous action potentials and secretion from rat lactotrophs
    • Sankaranarayanan S, Simasko SM. A role for a background sodium current in spontaneous action potentials and secretion from rat lactotrophs. Am J Physiol Cell Physiol 271: C1927-1934, 1996.
    • (1996) Am J Physiol Cell Physiol , vol.271
    • Sankaranarayanan, S.1    Simasko, S.M.2
  • 45
    • 0028328767 scopus 로고
    • A background sodium conductance is necessary for spontaneous depolarizations in rat pituitary cell line GH3
    • Simasko SM. A background sodium conductance is necessary for spontaneous depolarizations in rat pituitary cell line GH3. Am J Physiol Cell Physiol 266: C709-719, 1994.
    • (1994) Am J Physiol Cell Physiol , vol.266
    • Simasko, S.M.1
  • 46
    • 0030892934 scopus 로고    scopus 로고
    • Characterization of a hyperpolarization-activated cation current in rat pituitary cells
    • Simasko SM, Sankaranarayanan S. Characterization of a hyperpolarization-activated cation current in rat pituitary cells. Am J Physiol Endocrinol Metab 272: E405-414, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.272
    • Simasko, S.M.1    Sankaranarayanan, S.2
  • 47
    • 0025741172 scopus 로고
    • + conductance in freshly dispersed rat somatotrophs
    • + conductance in freshly dispersed rat somatotrophs. J Physiol 441: 615-637, 1991.
    • (1991) J Physiol , vol.441 , pp. 615-637
    • Sims, S.M.1    Lussier, B.T.2    Kraicer, J.3
  • 49
    • 0026695018 scopus 로고
    • Calcium oscillations in anterior pituitary cells
    • Stojilkovic SS, Catt KJ. Calcium oscillations in anterior pituitary cells. Endocr Rev 13: 256-280, 1992.
    • (1992) Endocr Rev , vol.13 , pp. 256-280
    • Stojilkovic, S.S.1    Catt, K.J.2
  • 53
    • 0033568862 scopus 로고    scopus 로고
    • Expression of Ca(2+)-mobilizing endothelin(A) receptors and their role in the control of Ca(2+) influx and growth hormone secretion in pituitary somatotrophs
    • Tomic M, Zivadinovic D, Van Goor F, Yuan D, Koshimizu T, Stojilkovic SS. Expression of Ca(2+)-mobilizing endothelin(A) receptors and their role in the control of Ca(2+) influx and growth hormone secretion in pituitary somatotrophs. J Neurosci 19: 7721-7731, 1999b.
    • (1999) J Neurosci , vol.19 , pp. 7721-7731
    • Tomic, M.1    Zivadinovic, D.2    Van Goor, F.3    Yuan, D.4    Koshimizu, T.5    Stojilkovic, S.S.6
  • 55
    • 0035823522 scopus 로고    scopus 로고
    • Dependence of pituitary hormone secretion on the pattern of spontaneous voltage-gated calcium influx. Cell type-specific action potential secretion coupling
    • van Goor F, Zivadinovic D, Martinez-Fuentes AJ, Stojilkovic SS. Dependence of pituitary hormone secretion on the pattern of spontaneous voltage-gated calcium influx. Cell type-specific action potential secretion coupling. J Biol Chem 276: 33840-33846, 2001b.
    • (2001) J Biol Chem , vol.276 , pp. 33840-33846
    • van Goor, F.1    Zivadinovic, D.2    Martinez-Fuentes, A.J.3    Stojilkovic, S.S.4
  • 56
    • 0034974361 scopus 로고    scopus 로고
    • Differential expression of ionic channels in rat anterior pituitary cells
    • van Goor F, Zivadinovic D, Stojilkovic SS. Differential expression of ionic channels in rat anterior pituitary cells. Mol Endocrinol 15: 1222-1236, 2001c.
    • (2001) Mol Endocrinol , vol.15 , pp. 1222-1236
    • van Goor, F.1    Zivadinovic, D.2    Stojilkovic, S.S.3
  • 57
    • 0025296969 scopus 로고
    • A-type receptors and activation of chloride and voltage-sensitive calcium channels
    • A-type receptors and activation of chloride and voltage-sensitive calcium channels. Endocrinology 126: 2499-2505, 1990.
    • (1990) Endocrinology , vol.126 , pp. 2499-2505
    • Virmani, M.A.1    Stojilkovic, S.S.2    Catt, K.J.3
  • 59
    • 0034059512 scopus 로고    scopus 로고
    • Expression of mRNA for voltage-dependent and inward-rectifying K channels in GH3/B6 cells and rat pituitary
    • Wulfsen I, Hauber HP, Schiemann D, Bauer CK, Schwarz JR. Expression of mRNA for voltage-dependent and inward-rectifying K channels in GH3/B6 cells and rat pituitary. J Neuroendocrinol 12: 263-272, 2000.
    • (2000) J Neuroendocrinol , vol.12 , pp. 263-272
    • Wulfsen, I.1    Hauber, H.P.2    Schiemann, D.3    Bauer, C.K.4    Schwarz, J.R.5
  • 60
    • 0033231526 scopus 로고    scopus 로고
    • + currents via a non-cAMP-dependent but PKC-mediated pathway in human GH adenoma cells
    • + currents via a non-cAMP-dependent but PKC-mediated pathway in human GH adenoma cells. J Physiol 520 Pt 3: 697-707, 1999.
    • (1999) J Physiol , vol.520 , Issue.PART 3 , pp. 697-707
    • Xu, R.1    Roh, S.G.2    Loneragan, K.3    Pullar, M.4    Chen, C.5
  • 61
    • 0036905839 scopus 로고    scopus 로고
    • + currents via a PKA-cAMP-mediated signalling pathway in ovine somatotropes
    • + currents via a PKA-cAMP-mediated signalling pathway in ovine somatotropes. J Physiol 545: 421-433, 2002.
    • (2002) J Physiol , vol.545 , pp. 421-433
    • Xu, R.1    Zhao, Y.2    Chen, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.