Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy

NeuroImage

Volumn 45, Issue 2, 2009, Pages 360-369

  McCann, Corey M ^a   Waterman, Peter ^a   Figueiredo, Jose Luiz ^a   Aikawa, Elena ^a   Weissleder, Ralph ^a   Chen, John W ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; GADOLINIUM PENTETATE; PROSENSE 680; PROTEINASE; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CANCER MORPHOLOGY; CONTROLLED STUDY; DRUG MEGADOSE; ENZYME ACTIVITY; FLUORESCENCE IMAGING; GLIOMA; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEASE ACTIVITY CONCENTRATION; QUANTITATIVE ANALYSIS; TREATMENT RESPONSE; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; CELL LINE, TUMOR; DACARBAZINE; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICROSCOPY, FLUORESCENCE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SUBTRACTION TECHNIQUE; TREATMENT OUTCOME;

EID: 60149098026     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2008.12.022     Document Type: Article

References (37)

1. Bindal A.K., Hammoud M., Shi W.M., Wu S.Z., Sawaya R., and Rao J.S. Prognostic significance of proteolytic enzymes in human brain tumors. J. Neuro-oncol. 22 (1994) 101-110
2. Blum G., Mullins S.R., Keren K., Fonovic M., Jedeszko C., Rice M.J., Sloane B.F., and Bogyo M. Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Nat. Chem. Biol. 1 (2005) 203-209
3. Brat D.J., Castellano-Sanchez A.A., Hunter S.B., Pecot M., Cohen C., Hammond E.H., Devi S.N., Kaur B., and Van Meir E.G. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res. 64 (2004) 920-927
4. Bremer C., Ntziachristos V., and Weissleder R. Optical-based molecular imaging: contrast agents and potential medical applications. Eur. Radiol. 13 (2003) 231-243
5. Graves E.E., Yessayan D., Turner G., Weissleder R., and Ntziachristos V. Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography. J. Biomed. Opt. 10 (2005) 44019
6. Hintersteiner M., Enz A., Frey P., Jaton A.L., Kinzy W., Kneuer R., Neumann U., Rudin M., Staufenbiel M., Stoeckli M., Wiederhold K.H., and Gremlich H.U. In vivo detection of amyloid-beta deposits by near-infrared imaging using an oxazine-derivative probe. Nat. Biotechnol. 23 (2005) 577-583
7. Izmailova E.S., Paz N., Alencar H., Chun M., Schopf L., Hepperle M., Lane J.H., Harriman G., Xu Y., Ocain T., Weissleder R., Mahmood U., Healy A.M., and Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum. 56 (2007) 117-128
8. Jaffer F.A., Libby P., and Weissleder R. Molecular and cellular imaging of atherosclerosis: emerging applications. J. Am. Coll. Cardiol. 47 (2006) 1328-1338
9. Jiang T., Olson E.S., Nguyen Q.T., Roy M., Jennings P.A., and Tsien R.Y. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 17867-17872
10. Kak A., and Slaney M. Principles of Computerized Tomographic Imaging (1988), IEEE Press, New York
11. Kelloff G.J., Krohn K.A., Larson S.M., Weissleder R., Mankoff D.A., Hoffman J.M., Link J.M., Guyton K.Z., Eckelman W.C., Scher H.I., O'Shaughnessy J., Cheson B.D., Sigman C.C., Tatum J.L., Mills G.Q., Sullivan D.C., and Woodcock J. The progress and promise of molecular imaging probes in oncologic drug development. Clin. Cancer Res. 11 (2005) 7967-7985
12. Koblinski J.E., Ahram M., and Sloane B.F. Unraveling the role of proteases in cancer. Clin. Chim. Acta 291 (2000) 113-135
13. Lardinois D., Weder W., Hany T.F., Kamel E.M., Korom S., Seifert B., von Schulthess G.K., and Steinert H.C. Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography. N. Engl. J. Med. 348 (2003) 2500-2507
14. Moffat B.A., Chenevert T.L., Lawrence T.S., Meyer C.R., Johnson T.D., Dong Q., Tsien C., Mukherji S., Quint D.J., Gebarski S.S., Robertson P.L., Junck L.R., Rehemtulla A., and Ross B.D. Functional diffusion map: a noninvasive MRI biomarker for early stratification of clinical brain tumor response. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 5524-5529
15. Monje M.L., Toda H., and Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 302 (2003) 1760-1765
16. Montet X., Ntziachristos V., Grimm J., and Weissleder R. Tomographic fluorescence mapping of tumor targets. Cancer Res. 65 (2005) 6330-6336
17. Nahrendorf M., Sosnovik D.E., Waterman P., Swirski F.K., Pande A.N., Aikawa E., Figueiredo J.L., Pittet M.J., and Weissleder R. Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct. Circ. Res. 100 (2007) 1218-1225
18. Nesterov E.E., Skoch J., Hyman B.T., Klunk W.E., Bacskai B.J., and Swager T.M. In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers. Angew. Chem., Int. Ed. Engl. 44 (2005) 5452-5456
19. Ntziachristos V., Yodh A.G., Schnall M., and Chance B. Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 2767-2772
20. Ntziachristos V., Bremer C., Graves E.E., Ripoll J., and Weissleder R. In vivo tomographic imaging of near-infrared fluorescent probes. Mol. Imaging 1 (2002) 82-88
21. Ntziachristos V., Ripoll J., and Weissleder R. Would near-infrared fluorescence signals propagate through large human organs for clinical studies?. Opt. Lett. 27 (2002) 333-335
22. Ntziachristos V., Tung C.H., Bremer C., and Weissleder R. Fluorescence molecular tomography resolves protease activity in vivo. Nat. Med. 8 (2002) 757-760
23. Ntziachristos V., Bremer C., and Weissleder R. Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur. Radiol. 13 (2003) 195-208
24. Ntziachristos V., Schellenberger E.A., Ripoll J., Yessayan D., Graves E., Bogdanov Jr. A., Josephson L., and Weissleder R. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 12294-12299
25. Ntziachristos V., Ripoll J., Wang L.V., and Weissleder R. Looking and listening to light: the evolution of whole-body photonic imaging. Nat. Biotechnol. 23 (2005) 313-320
26. Otsuka H., Morita N., Yamashita K., and Nishitani H. FDG-PET/CT for cancer management. J. Med. Investig. 54 (2007) 195-199
27. Schiff D. Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation. Cancer Investig. 25 (2007) 776-784
28. Shcherbo D., Merzlyak E.M., Chepurnykh T.V., Fradkov A.F., Ermakova G.V., Solovieva E.A., Lukyanov K.A., Bogdanova E.A., Zaraisky A.G., Lukyanov S., and Chudakov D.M. Bright far-red fluorescent protein for whole-body imaging. Nat. Methods 4 (2007) 741-746
29. Sloane B.F. Suicidal tumor proteases. Nat. Biotechnol. 14 (1996) 826-827
30. Trehin R., Figueiredo J.L., Pittet M.J., Weissleder R., Josephson L., and Mahmood U. Fluorescent nanoparticle uptake for brain tumor visualization. Neoplasia 8 (2006) 302-311
31. Vasiljeva O., Papazoglou A., Kruger A., Brodoefel H., Korovin M., Deussing J., Augustin N., Nielsen B.S., Almholt K., Bogyo M., Peters C., and Reinheckel T. Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer. Cancer Res. 66 (2006) 5242-5250
32. Veit-Haibach P., Kuehle C.A., Beyer T., Stergar H., Kuehl H., Schmidt J., Borsch G., Dahmen G., Barkhausen J., Bockisch A., and Antoch G. Diagnostic accuracy of colorectal cancer staging with whole-body PET/CT colonography. Jama 296 (2006) 2590-2600
33. von Wallbrunn A., Holtke C., Zuhlsdorf M., Heindel W., Schafers M., and Bremer C. In vivo imaging of integrin alpha v beta 3 expression using fluorescence-mediated tomography. Eur. J. Nucl. Med. Mol. Imaging 34 (2007) 745-754
34. Weber W.A., Grosu A.L., and Czernin J. Technology insight: advances in molecular imaging and an appraisal of PET/CT scanning. Nat. Clin. Pract. Oncol. 5 (2008) 160-170
35. Weissleder R., and Ntziachristos V. Shedding light onto live molecular targets. Nat. Med. 9 (2003) 123-128
36. Weissleder R., Tung C.H., Mahmood U., and Bogdanov Jr. A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat. Biotechnol. 17 (1999) 375-378
37. Zacharakis G., Kambara H., Shih H., Ripoll J., Grimm J., Saeki Y., Weissleder R., and Ntziachristos V. Volumetric tomography of fluorescent proteins through small animals in vivo. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 18252-18257