메뉴 건너뛰기




Volumn 52, Issue 9, 2008, Pages 1416-1429

Cardiovascular disturbances in acromegaly;Distúrbios cardiovasculares na acromegalia

Author keywords

Acromegalic cardiomyopathy; Acromegaly; Cardiovascular risk; Secondary hypertension

Indexed keywords

HUMAN GROWTH HORMONE; SOMATOMEDIN C;

EID: 60149094172     PISSN: 00042730     EISSN: 16779487     Source Type: Journal    
DOI: 10.1590/S0004-27302008000900004     Document Type: Review
Times cited : (10)

References (69)
  • 1
    • 0033139863 scopus 로고    scopus 로고
    • Epidemiology of acromegaly
    • Holdaway IM, Rajasoorya C. Epidemiology of acromegaly. Pituitary. 1999;2(1):29-41.
    • (1999) Pituitary , vol.2 , Issue.1 , pp. 29-41
    • Holdaway, I.M.1    Rajasoorya, C.2
  • 2
    • 4744348959 scopus 로고    scopus 로고
    • Acromegaly
    • Melmed S, ed, Massachusets: Blackwell Publishing
    • Melmed S. Acromegaly. In: Melmed S, ed. The Pituitary. Massachusets: Blackwell Publishing. 2002. p.419-54.
    • (2002) The Pituitary , pp. 419-454
    • Melmed, S.1
  • 3
    • 1442326975 scopus 로고    scopus 로고
    • Systemic complications of acromegaly: Epidemiology, pathogenesis, and management
    • Colao A, Ferone D, Marzullo P, Lombardi G. Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev. 2004;25(1):102-52.
    • (2004) Endocr Rev , vol.25 , Issue.1 , pp. 102-152
    • Colao, A.1    Ferone, D.2    Marzullo, P.3    Lombardi, G.4
  • 4
    • 33845491265 scopus 로고    scopus 로고
    • Medical progress: Acromegaly
    • Melmed S. Medical progress: acromegaly. N Engl J Med. 2006;355(24):2558-73.
    • (2006) N Engl J Med , vol.355 , Issue.24 , pp. 2558-2573
    • Melmed, S.1
  • 5
    • 4644304160 scopus 로고    scopus 로고
    • Cardiac abnormalities in acromegaly. Pathophysiology and implications for management
    • Vitale G, Pivonello R, Lombardi G, Colao A. Cardiac abnormalities in acromegaly. Pathophysiology and implications for management. Treat Endocrinol. 2004;3(5):309-18.
    • (2004) Treat Endocrinol , vol.3 , Issue.5 , pp. 309-318
    • Vitale, G.1    Pivonello, R.2    Lombardi, G.3    Colao, A.4
  • 6
    • 0038646354 scopus 로고    scopus 로고
    • Cardiovascular function in acromegaly
    • Clayton RN. Cardiovascular function in acromegaly. Endocr Rev. 2003;24(3):272-7.
    • (2003) Endocr Rev , vol.24 , Issue.3 , pp. 272-277
    • Clayton, R.N.1
  • 7
    • 0035723837 scopus 로고    scopus 로고
    • Characterization of premature atherosclerosis of carotid arteries in acromegalic patients
    • Otsuki M, Kasayama S, Yamamoto H, Saito H, Sumitani S, Kouhara H, et al. Characterization of premature atherosclerosis of carotid arteries in acromegalic patients. Clin Endocrinol (Oxf). 2001;54(6):791-6.
    • (2001) Clin Endocrinol (Oxf) , vol.54 , Issue.6 , pp. 791-796
    • Otsuki, M.1    Kasayama, S.2    Yamamoto, H.3    Saito, H.4    Sumitani, S.5    Kouhara, H.6
  • 8
    • 34447577819 scopus 로고    scopus 로고
    • Current thinking on the management of the acromegalic patient
    • Katznelson L. Current thinking on the management of the acromegalic patient. Curr Opin Endocrinol Diabetes Obes. 2007;14(4):311-6.
    • (2007) Curr Opin Endocrinol Diabetes Obes , vol.14 , Issue.4 , pp. 311-316
    • Katznelson, L.1
  • 9
    • 7244257406 scopus 로고    scopus 로고
    • Epidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Espanol de Acromegalia, REA)
    • Mestron A, Webb SM, Astorga R, Benito P, Catala M, Gaztambide S, et al. Epidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Espanol de Acromegalia, REA). Eur J Endocrinol. 2004;151(4):439-46.
    • (2004) Eur J Endocrinol , vol.151 , Issue.4 , pp. 439-446
    • Mestron, A.1    Webb, S.M.2    Astorga, R.3    Benito, P.4    Catala, M.5    Gaztambide, S.6
  • 12
    • 34547903604 scopus 로고    scopus 로고
    • Growth hormone (GH) and IGF-I assays: Methodological aspects and its implications in acromegaly diagnosis and follow-up. Arq Bras Endocrinol
    • Casagrande A, Czepielewski MA. Growth hormone (GH) and IGF-I assays: methodological aspects and its implications in acromegaly diagnosis and follow-up. Arq Bras Endocrinol Metabol. 2007;51(4):511-9.
    • (2007) Metabol , vol.51 , Issue.4 , pp. 511-519
    • Casagrande, A.1    Czepielewski, M.A.2
  • 13
    • 0031871481 scopus 로고    scopus 로고
    • Echocardiographic evidence for a direct effect of GH/IGF-I hypersecretion on cardiac mass and function in young acromegalics
    • Minniti G, Jaffrain-Rea ML, Moroni C, Baldelli R, Ferretti E, Cassone R, et al. Echocardiographic evidence for a direct effect of GH/IGF-I hypersecretion on cardiac mass and function in young acromegalics. Clin Endocrinol (Oxf). 1998;49(1):101-6.
    • (1998) Clin Endocrinol (Oxf) , vol.49 , Issue.1 , pp. 101-106
    • Minniti, G.1    Jaffrain-Rea, M.L.2    Moroni, C.3    Baldelli, R.4    Ferretti, E.5    Cassone, R.6
  • 15
    • 0027970820 scopus 로고
    • Growth hormone and the heart
    • Sacca L, Cittadini A, Fazio S. Growth hormone and the heart. Endocr Rev. 1994;15(5):555-73.
    • (1994) Endocr Rev , vol.15 , Issue.5 , pp. 555-573
    • Sacca, L.1    Cittadini, A.2    Fazio, S.3
  • 16
    • 1542269637 scopus 로고    scopus 로고
    • Prevalence and determinants of left ventricular hypertrophy in acromegaly: Impact of different methods of indexing left ventricular mass
    • Vitale G, Galderisi M, Pivonello R, Spinelli L, Ciccarelli A, de Divitiis O, et al. Prevalence and determinants of left ventricular hypertrophy in acromegaly: impact of different methods of indexing left ventricular mass. Clin Endocrinol (Oxf). 2004;60(3): 343-9.
    • (2004) Clin Endocrinol (Oxf) , vol.60 , Issue.3 , pp. 343-349
    • Vitale, G.1    Galderisi, M.2    Pivonello, R.3    Spinelli, L.4    Ciccarelli, A.5    de Divitiis, O.6
  • 18
    • 33646740349 scopus 로고    scopus 로고
    • Cardiac morphology and performance alterations and analysis of determinant factors of left ventricular hypertrophy in 40 patients with acromegaly. Arq Bras Endocrinol
    • Casini AF, Araujo PB, Fontes R, Xavier SS, Gadelha MR. Cardiac morphology and performance alterations and analysis of determinant factors of left ventricular hypertrophy in 40 patients with acromegaly. Arq Bras Endocrinol Metabol. 2006;50(1):82-90.
    • (2006) Metabol , vol.50 , Issue.1 , pp. 82-90
    • Casini, A.F.1    Araujo, P.B.2    Fontes, R.3    Xavier, S.S.4    Gadelha, M.R.5
  • 21
    • 0021984429 scopus 로고
    • Progression of cardiovascular disease in acromegalic patients treated by external pituitary irradiation
    • Baldwin A, Cundy T, Butler J, Timmis AD. Progression of cardiovascular disease in acromegalic patients treated by external pituitary irradiation. Acta Endocrinol (Copenh). 1985;108(1):26-30.
    • (1985) Acta Endocrinol (Copenh) , vol.108 , Issue.1 , pp. 26-30
    • Baldwin, A.1    Cundy, T.2    Butler, J.3    Timmis, A.D.4
  • 22
    • 0035040518 scopus 로고    scopus 로고
    • Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance
    • Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Della Morte AM, et al. Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance. J Clin Endocrinol Metabolism. 2001;86(4):1551-7.
    • (2001) J Clin Endocrinol Metabolism , vol.86 , Issue.4 , pp. 1551-1557
    • Colao, A.1    Cuocolo, A.2    Marzullo, P.3    Nicolai, E.4    Ferone, D.5    Della Morte, A.M.6
  • 23
    • 0034852751 scopus 로고    scopus 로고
    • Marked improvement in cardiovascular function after successful transsphenoidal surgery in acromegalic patients
    • Minniti G, Moroni C, Jaffrain-Rea ML, Esposito V, Santoro A, Affricano C, et al. Marked improvement in cardiovascular function after successful transsphenoidal surgery in acromegalic patients. Clin Endocrinol (Oxf). 2001;55(3):307-13.
    • (2001) Clin Endocrinol (Oxf) , vol.55 , Issue.3 , pp. 307-313
    • Minniti, G.1    Moroni, C.2    Jaffrain-Rea, M.L.3    Esposito, V.4    Santoro, A.5    Affricano, C.6
  • 24
    • 4444272797 scopus 로고    scopus 로고
    • Evaluation of cardiac structure by echorefl ectivity analysis in acromegaly: Effects of treatment
    • Ciulla MM, Epaminonda P, Paliotti R, Barelli MV, Ronchi C, Cappiello V, et al. Evaluation of cardiac structure by echorefl ectivity analysis in acromegaly: effects of treatment. Eur J Endocrinol. 2004;151(2):179-86.
    • (2004) Eur J Endocrinol , vol.151 , Issue.2 , pp. 179-186
    • Ciulla, M.M.1    Epaminonda, P.2    Paliotti, R.3    Barelli, M.V.4    Ronchi, C.5    Cappiello, V.6
  • 25
    • 0037318794 scopus 로고    scopus 로고
    • Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide
    • Colao A, Marzullo P, Cuocolo A, Spinelli L, Pivonello R, Bonaduce D, et al. Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide. Clin Endocrinol (Oxf). 2003;58(2):169-76.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , Issue.2 , pp. 169-176
    • Colao, A.1    Marzullo, P.2    Cuocolo, A.3    Spinelli, L.4    Pivonello, R.5    Bonaduce, D.6
  • 29
    • 33750085284 scopus 로고    scopus 로고
    • Effects of treatment with somatostatin analogues on QT interval duration in acromegalic patients
    • Fatti LM, Scacchi M, Lavezzi E, Pecori Giraldi F, De Martin M, Toja P, et al. Effects of treatment with somatostatin analogues on QT interval duration in acromegalic patients. Clin Endocrinol (Oxf). 2006;65(5):626-30.
    • (2006) Clin Endocrinol (Oxf) , vol.65 , Issue.5 , pp. 626-630
    • Fatti, L.M.1    Scacchi, M.2    Lavezzi, E.3    Pecori Giraldi, F.4    De Martin, M.5    Toja, P.6
  • 31
    • 12244286036 scopus 로고    scopus 로고
    • Improvement of left ventricular hypertrophy and arrhythmias after lanreotide-induced GH and IGF-I decrease in acromegaly. A prospective multi-center study
    • Lombardi G, Colao A, Marzullo P, Biondi B, Palmieri E, Fazio S. Improvement of left ventricular hypertrophy and arrhythmias after lanreotide-induced GH and IGF-I decrease in acromegaly. A prospective multi-center study. J Endocrinol Invest. 2002;25(11):971-6.
    • (2002) J Endocrinol Invest , vol.25 , Issue.11 , pp. 971-976
    • Lombardi, G.1    Colao, A.2    Marzullo, P.3    Biondi, B.4    Palmieri, E.5    Fazio, S.6
  • 32
    • 0037961032 scopus 로고    scopus 로고
    • High prevalence of cardiac valve disease in acromegaly: An observational, analytical, case-control study
    • Colao A, Spinelli L, Marzullo P, Pivonello R, Petretta M, Di Somma C, et al. High prevalence of cardiac valve disease in acromegaly: an observational, analytical, case-control study. J Clin Endocrinol Metabolism. 2003;88(7):3196-201.
    • (2003) J Clin Endocrinol Metabolism , vol.88 , Issue.7 , pp. 3196-3201
    • Colao, A.1    Spinelli, L.2    Marzullo, P.3    Pivonello, R.4    Petretta, M.5    Di Somma, C.6
  • 33
    • 0018871602 scopus 로고
    • Pathology of the heart in acromegaly: Anatomic findings in 27 autopsied patients
    • Lie JT. Pathology of the heart in acromegaly: anatomic findings in 27 autopsied patients. Am Heart J. 1980;100(1):41-52.
    • (1980) Am Heart J , vol.100 , Issue.1 , pp. 41-52
    • Lie, J.T.1
  • 37
    • 33845974147 scopus 로고    scopus 로고
    • Valvular heart disease and the use of dopamine agonists for Parkinson's disease
    • Zanettini R, Antonini A, Gatto G, Gentile R, Tesei S, Pezzoli G. Valvular heart disease and the use of dopamine agonists for Parkinson's disease. N Engl J Med. 2007;356(1):39-46.
    • (2007) N Engl J Med , vol.356 , Issue.1 , pp. 39-46
    • Zanettini, R.1    Antonini, A.2    Gatto, G.3    Gentile, R.4    Tesei, S.5    Pezzoli, G.6
  • 38
  • 39
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. New England Journal of Medicine. 1999;340(2):115-26.
    • (1999) New England Journal of Medicine , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 41
    • 0033785894 scopus 로고    scopus 로고
    • Vascular reactivity in acromegalic patients: Preliminary evidence for regional endothelial dysfunction and increased sympathetic vasoconstriction
    • Maison P, Demolis P, Young J, Schaison G, Giudicelli JF, Chanson P. Vascular reactivity in acromegalic patients: preliminary evidence for regional endothelial dysfunction and increased sympathetic vasoconstriction. Clin Endocrinol (Oxf). 2000;53(4):445-51.
    • (2000) Clin Endocrinol (Oxf) , vol.53 , Issue.4 , pp. 445-451
    • Maison, P.1    Demolis, P.2    Young, J.3    Schaison, G.4    Giudicelli, J.F.5    Chanson, P.6
  • 44
    • 0035725059 scopus 로고    scopus 로고
    • Increased arterial intima-media thickness by B-M mode echodoppler ultrasonography in acromegaly
    • Colao A, Spiezia S, Cerbone G, Pivonello R, Marzullo P, Ferone D, et al. Increased arterial intima-media thickness by B-M mode echodoppler ultrasonography in acromegaly. Clin Endocrinol (Oxf). 2001;54(4):515-24.
    • (2001) Clin Endocrinol (Oxf) , vol.54 , Issue.4 , pp. 515-524
    • Colao, A.1    Spiezia, S.2    Cerbone, G.3    Pivonello, R.4    Marzullo, P.5    Ferone, D.6
  • 46
    • 33749542715 scopus 로고    scopus 로고
    • Acromegaly and coronary disease: An integrated evaluation of conventional coronary risk factors and coronary calcifications detected by computed tomography
    • Cannavo S, Almoto B, Cavalli G, Squadrito S, Romanello G, Vigo MT, et al. Acromegaly and coronary disease: an integrated evaluation of conventional coronary risk factors and coronary calcifications detected by computed tomography. J Clin Endocrinol Metabolism. 2006;91(10):3766-72.
    • (2006) J Clin Endocrinol Metabolism , vol.91 , Issue.10 , pp. 3766-3772
    • Cannavo, S.1    Almoto, B.2    Cavalli, G.3    Squadrito, S.4    Romanello, G.5    Vigo, M.T.6
  • 47
    • 36048946304 scopus 로고    scopus 로고
    • Risk factors for development of coronary heart disease in patients with acromegaly: A five-year prospective study
    • Bogazzi F, Battolla L, Spinelli C, Rossi G, Gavioli S, Di Bello V, et al. Risk factors for development of coronary heart disease in patients with acromegaly: a five-year prospective study. J Clin Endocrinol Metabolism. 2007;92(11):4271-7.
    • (2007) J Clin Endocrinol Metabolism , vol.92 , Issue.11 , pp. 4271-4277
    • Bogazzi, F.1    Battolla, L.2    Spinelli, C.3    Rossi, G.4    Gavioli, S.5    Di Bello, V.6
  • 51
    • 0038644714 scopus 로고    scopus 로고
    • The effects of depot long-acting somatostatin analog on central aortic pressure and arterial stiffness in acromegaly
    • Smith JC, Lane H, Davies N, Evans LM, Cockcroft J, Scanlon MF, et al. The effects of depot long-acting somatostatin analog on central aortic pressure and arterial stiffness in acromegaly. J Clin Endocrinol Metabolism. 2003;88(6):2556-61.
    • (2003) J Clin Endocrinol Metabolism , vol.88 , Issue.6 , pp. 2556-2561
    • Smith, J.C.1    Lane, H.2    Davies, N.3    Evans, L.M.4    Cockcroft, J.5    Scanlon, M.F.6
  • 52
    • 10744228810 scopus 로고    scopus 로고
    • Acromegalic patients show the presence of hypertrophic remodeling of subcutaneous small resistance arteries
    • Rizzoni D, Porteri E, Giustina A, De Ciuceis C, Sleiman I, Boari GE, et al. Acromegalic patients show the presence of hypertrophic remodeling of subcutaneous small resistance arteries. Hypertension. 2004;43(3):561-5.
    • (2004) Hypertension , vol.43 , Issue.3 , pp. 561-565
    • Rizzoni, D.1    Porteri, E.2    Giustina, A.3    De Ciuceis, C.4    Sleiman, I.5    Boari, G.E.6
  • 53
    • 0034090236 scopus 로고    scopus 로고
    • Baseline and stimulated catecholamine secretion in normotensive patients with active acromegaly: Acute effects of continuous octreotide infusion
    • Rio GD, Velardo A, Mascadri C, Zalteri G, Papi G, Menozzi R, et al. Baseline and stimulated catecholamine secretion in normotensive patients with active acromegaly: acute effects of continuous octreotide infusion. Eur J Endocrinol. 2000;142(2):179-86.
    • (2000) Eur J Endocrinol , vol.142 , Issue.2 , pp. 179-186
    • Rio, G.D.1    Velardo, A.2    Mascadri, C.3    Zalteri, G.4    Papi, G.5    Menozzi, R.6
  • 56
    • 0029964803 scopus 로고    scopus 로고
    • Growth hormone, the insulin-like growth factor system, and the kidney
    • Feld S, Hirschberg R. Growth hormone, the insulin-like growth factor system, and the kidney. Endocr Rev. 1996;17(5):423-80.
    • (1996) Endocr Rev , vol.17 , Issue.5 , pp. 423-480
    • Feld, S.1    Hirschberg, R.2
  • 57
    • 17744362863 scopus 로고    scopus 로고
    • Systemic hypertension and impaired glucose tolerance are independently correlated to the severity of the acromegalic cardiomyopathy
    • Colao A, Baldelli R, Marzullo P, Ferretti E, Ferone D, Gargiulo P, et al. Systemic hypertension and impaired glucose tolerance are independently correlated to the severity of the acromegalic cardiomyopathy. J Clin Endocrinol Metabolism. 2000;85(1):193-9.
    • (2000) J Clin Endocrinol Metabolism , vol.85 , Issue.1 , pp. 193-199
    • Colao, A.1    Baldelli, R.2    Marzullo, P.3    Ferretti, E.4    Ferone, D.5    Gargiulo, P.6
  • 58
    • 30344460510 scopus 로고    scopus 로고
    • Comparison between six-year therapy with long-acting somatostatin analogs and successful surgery in acromegaly: Effects on cardiovascular risk factors
    • Ronchi CL, Varca V, Beck-Peccoz P, Orsi E, Donadio F, Baccarelli A, et al. Comparison between six-year therapy with long-acting somatostatin analogs and successful surgery in acromegaly: effects on cardiovascular risk factors. J Clin Endocrinol Metabolism. 2006;91(1):121-8.
    • (2006) J Clin Endocrinol Metabolism , vol.91 , Issue.1 , pp. 121-128
    • Ronchi, C.L.1    Varca, V.2    Beck-Peccoz, P.3    Orsi, E.4    Donadio, F.5    Baccarelli, A.6
  • 61
    • 34548447989 scopus 로고    scopus 로고
    • Increase of classic and nonclassic cardiovascular risk factors in patients with acromegaly
    • Vilar L, Naves LA, Costa SS, Abdalla LF, Coelho CE, Casulari LA. Increase of classic and nonclassic cardiovascular risk factors in patients with acromegaly. Endocr Pract. 2007;13(4):363-72.
    • (2007) Endocr Pract , vol.13 , Issue.4 , pp. 363-372
    • Vilar, L.1    Naves, L.A.2    Costa, S.S.3    Abdalla, L.F.4    Coelho, C.E.5    Casulari, L.A.6
  • 62
    • 0028882919 scopus 로고
    • Effects of treatment with octreotide in acromegalic patients-a multicenter Italian study. Italian Multicenter Octreotide Study Group
    • Arosio M, Macchelli S, Rossi CM, Casati G, Biella O, Faglia G. Effects of treatment with octreotide in acromegalic patients-a multicenter Italian study. Italian Multicenter Octreotide Study Group. Eur J Endocrinol. 1995;133(4):430-9.
    • (1995) Eur J Endocrinol , vol.133 , Issue.4 , pp. 430-439
    • Arosio, M.1    Macchelli, S.2    Rossi, C.M.3    Casati, G.4    Biella, O.5    Faglia, G.6
  • 63
    • 0035677240 scopus 로고    scopus 로고
    • Risk factors for glucose intolerance in active acromegaly
    • Kreze A, Kreze-Spirova E, Mikulecky M. Risk factors for glucose intolerance in active acromegaly. Braz J Med Biol Res. 2001;34(11):1429-33.
    • (2001) Braz J Med Biol Res , vol.34 , Issue.11 , pp. 1429-1433
    • Kreze, A.1    Kreze-Spirova, E.2    Mikulecky, M.3
  • 65
    • 0036891721 scopus 로고    scopus 로고
    • Growth hormone receptor antagonist improves insulin resistance in acromegaly
    • Rose DR, Clemmons DR. Growth hormone receptor antagonist improves insulin resistance in acromegaly. Growth Horm IGF Res. 2002;12(6):418-24.
    • (2002) Growth Horm IGF Res , vol.12 , Issue.6 , pp. 418-424
    • Rose, D.R.1    Clemmons, D.R.2
  • 66
    • 0035944825 scopus 로고    scopus 로고
    • Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist
    • van der Lely AJ, Hutson RK, Trainer PJ, Besser GM, Barkan AL, Katznelson L, et al. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet. 2001;358(9295):1754-9.
    • (2001) Lancet , vol.358 , Issue.9295 , pp. 1754-1759
    • van der Lely, A.J.1    Hutson, R.K.2    Trainer, P.J.3    Besser, G.M.4    Barkan, A.L.5    Katznelson, L.6
  • 67
    • 18444366740 scopus 로고    scopus 로고
    • Cardiovascular risk factors in acromegaly before and after normalization of serum IGF-I levels with the GH antagonist pegvisomant
    • Sesmilo G, Fairfield WP, Katznelson L, Pulaski K, Freda PU, Bonert V, et al. Cardiovascular risk factors in acromegaly before and after normalization of serum IGF-I levels with the GH antagonist pegvisomant. J Clin Endocrinol Metabolism. 2002;87(4):1692-9.
    • (2002) J Clin Endocrinol Metabolism , vol.87 , Issue.4 , pp. 1692-1699
    • Sesmilo, G.1    Fairfield, W.P.2    Katznelson, L.3    Pulaski, K.4    Freda, P.U.5    Bonert, V.6
  • 68
    • 0036231569 scopus 로고    scopus 로고
    • Serum lipoprotein changes following IGF-I normalization using a growth hormone receptor antagonist in acromegaly
    • Parkinson C, Drake WM, Wieringa G, Yates AP, Besser GM, Trainer PJ. Serum lipoprotein changes following IGF-I normalization using a growth hormone receptor antagonist in acromegaly. Clin Endocrinol (Oxf). 2002;56(3):303-11.
    • (2002) Clin Endocrinol (Oxf) , vol.56 , Issue.3 , pp. 303-311
    • Parkinson, C.1    Drake, W.M.2    Wieringa, G.3    Yates, A.P.4    Besser, G.M.5    Trainer, P.J.6
  • 69
    • 0031759850 scopus 로고    scopus 로고
    • Mortality and cancer incidence in acromegaly: A retrospective cohort study. United Kingdom Acromegaly Study Group
    • Orme SM, McNally RJ, Cartwright RA, Belchetz PE. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. J Clin Endocrinol Metabolism. 1998;83(8):2730-4.
    • (1998) J Clin Endocrinol Metabolism , vol.83 , Issue.8 , pp. 2730-2734
    • Orme, S.M.1    McNally, R.J.2    Cartwright, R.A.3    Belchetz, P.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.