-
2
-
-
1442326975
-
Systemic complications of acromegaly: Epidemiology, pathogenesis, and management
-
Colao A, Ferone D, Marzullo P, Lombardi G. Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev 2004; 25:102-152.
-
(2004)
Endocr Rev
, vol.25
, pp. 102-152
-
-
Colao, A.1
Ferone, D.2
Marzullo, P.3
Lombardi, G.4
-
3
-
-
22744440855
-
Diagnosis and treatment of acromegaly
-
Katznelson L. Diagnosis and treatment of acromegaly. Growth Horm IGF Res 2005; 15 (Suppl A):A31-A35.
-
(2005)
Growth Horm IGF Res
, vol.15
, Issue.SUPPL. A
-
-
Katznelson, L.1
-
4
-
-
0025700486
-
Acromegaly
-
Melmed S. Acromegaly. N Engl J Med 1990; 322:966-977.
-
(1990)
N Engl J Med
, vol.322
, pp. 966-977
-
-
Melmed, S.1
-
5
-
-
34147169560
-
Effect of transsphenoidal surgery on sleep apnoea in acromegaly
-
Sze L, Schmid C, Bloch KE, et al. Effect of transsphenoidal surgery on sleep apnoea in acromegaly. Eur J Endocrinol 2007; 156:321-329.
-
(2007)
Eur J Endocrinol
, vol.156
, pp. 321-329
-
-
Sze, L.1
Schmid, C.2
Bloch, K.E.3
-
6
-
-
0025943847
-
-
Grunstein RR, Ho KY, Sullivan CE. Sleep apnea in acromegaly. Ann Intern Med 1991; 115:527-532.
-
Grunstein RR, Ho KY, Sullivan CE. Sleep apnea in acromegaly. Ann Intern Med 1991; 115:527-532.
-
-
-
-
7
-
-
19144366774
-
Risk of colorectal neoplasm in patients with acromegaly and its relationship with serum growth hormone levels
-
Matano Y, Okada T, Suzuki A, et al. Risk of colorectal neoplasm in patients with acromegaly and its relationship with serum growth hormone levels. Am J Gastroenterol 2005; 100:1154-1160.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 1154-1160
-
-
Matano, Y.1
Okada, T.2
Suzuki, A.3
-
8
-
-
0028818513
-
The prevalence of colonic polyps in acromegaly: A colonoscopic and pathological study in 103 patients
-
Delhougne B, Deneux C, Abs R, et al. The prevalence of colonic polyps in acromegaly: a colonoscopic and pathological study in 103 patients. J Clin Endocrinol Metab 1995; 80:3223-3226.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3223-3226
-
-
Delhougne, B.1
Deneux, C.2
Abs, R.3
-
9
-
-
17244362859
-
Acromegaly and cancer
-
Jenkins PJ. Acromegaly and cancer. Horm Res 2004; 62 (Suppl 1):108-115.
-
(2004)
Horm Res
, vol.62
, Issue.SUPPL. 1
, pp. 108-115
-
-
Jenkins, P.J.1
-
11
-
-
0026341594
-
Acromegaly and gastrointestinal cancer
-
Ron E, Gridley G, Hrubec Z, et al. Acromegaly and gastrointestinal cancer. Cancer 1991; 68:1673-1677.
-
(1991)
Cancer
, vol.68
, pp. 1673-1677
-
-
Ron, E.1
Gridley, G.2
Hrubec, Z.3
-
12
-
-
0033710082
-
Cardiovascular effects of depot long-acting somatostatin analog Sandostatin LAR in acromegaly
-
Colao A, Marzullo P, Ferone D, et al. Cardiovascular effects of depot long-acting somatostatin analog Sandostatin LAR in acromegaly. J Clin Endocrinol Metab 2000; 85:3132-3140.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3132-3140
-
-
Colao, A.1
Marzullo, P.2
Ferone, D.3
-
13
-
-
4644265458
-
The heart: An end-organ of GH action
-
Colao A, Vitale G, Pivonello R, et al. The heart: an end-organ of GH action. Eur J Endocrinol 2004; 151 (Suppl 1):S93-S101.
-
(2004)
Eur J Endocrinol
, vol.151
, Issue.SUPPL. 1
-
-
Colao, A.1
Vitale, G.2
Pivonello, R.3
-
14
-
-
0026705639
-
Clinical manifestations of acromegaly
-
Molitch ME. Clinical manifestations of acromegaly. Endocrinol Metab Clin North Am 1992; 21:597-614.
-
(1992)
Endocrinol Metab Clin North Am
, vol.21
, pp. 597-614
-
-
Molitch, M.E.1
-
15
-
-
26644464576
-
Hypertension in acromegaly and in the normal population: Prevalence and determinants
-
Vitale G, Pivonello R, Auriemma RS, et al. Hypertension in acromegaly and in the normal population: prevalence and determinants. Clin Endocrinol (Oxf) 2005; 63:470-476.
-
(2005)
Clin Endocrinol (Oxf)
, vol.63
, pp. 470-476
-
-
Vitale, G.1
Pivonello, R.2
Auriemma, R.S.3
-
16
-
-
0033867735
-
LDL physical properties, lipoprotein and Lp(a) levels in acromegalic patients. Effects of octreotide therapy. Italian Multicenter Octreotide Study Group
-
Arosio M, Sartore G, Rossi CM, et al. LDL physical properties, lipoprotein and Lp(a) levels in acromegalic patients. Effects of octreotide therapy. Italian Multicenter Octreotide Study Group. Atherosclerosis 2000; 151:551-557.
-
(2000)
Atherosclerosis
, vol.151
, pp. 551-557
-
-
Arosio, M.1
Sartore, G.2
Rossi, C.M.3
-
18
-
-
25844458249
-
Reduced nitric oxide levels in acromegaly: Cardiovascular implications
-
Ronconi V, Giacchetti G, Mariniello B, et al. Reduced nitric oxide levels in acromegaly: cardiovascular implications. Blood Press 2005; 14:227-232.
-
(2005)
Blood Press
, vol.14
, pp. 227-232
-
-
Ronconi, V.1
Giacchetti, G.2
Mariniello, B.3
-
19
-
-
30344460510
-
-
Ronchi CL, Varca V, Beck-Peccoz P, et al. Comparison between six-year therapy with long-acting somatostatin analogs and successful surgery in acromegaly: effects on cardiovascular risk factors. J Clin Endocrinol Metab 2006; 91:121-128. An excellent prospective study on the effects of somatostatin analogs on cardiovascular risk factors. This study, excluding radiation-treated subjects, is controlled and demonstrates the variable effects of somatostatin analogs on glucose homeostasis over a 6-year follow-up.
-
Ronchi CL, Varca V, Beck-Peccoz P, et al. Comparison between six-year therapy with long-acting somatostatin analogs and successful surgery in acromegaly: effects on cardiovascular risk factors. J Clin Endocrinol Metab 2006; 91:121-128. An excellent prospective study on the effects of somatostatin analogs on cardiovascular risk factors. This study, excluding radiation-treated subjects, is controlled and demonstrates the variable effects of somatostatin analogs on glucose homeostasis over a 6-year follow-up.
-
-
-
-
20
-
-
33645221483
-
Efficacy of 12-month treatment with the GH receptor antagonist pegvisomant in patients with acromegaly resistant to long-term, high-dose somatostatin analog treatment: Effect on IGF-I levels, tumor mass, hypertension and glucose tolerance
-
This study demonstrates the benefit of pegvisomant on cardiovascular risk profiles
-
Colao A, Pivonello R, Auriemma RS, et al. Efficacy of 12-month treatment with the GH receptor antagonist pegvisomant in patients with acromegaly resistant to long-term, high-dose somatostatin analog treatment: effect on IGF-I levels, tumor mass, hypertension and glucose tolerance. Eur J Endocrinol 2006; 154:467-477. This study demonstrates the benefit of pegvisomant on cardiovascular risk profiles.
-
(2006)
Eur J Endocrinol
, vol.154
, pp. 467-477
-
-
Colao, A.1
Pivonello, R.2
Auriemma, R.S.3
-
21
-
-
20444443924
-
The effect of atorvastatin on serum lipoproteins in acromegaly
-
Mishra M, Durrington P, Mackness M, et al. The effect of atorvastatin on serum lipoproteins in acromegaly. Clin Endocrinol (Oxf) 2005; 62:650-655.
-
(2005)
Clin Endocrinol (Oxf)
, vol.62
, pp. 650-655
-
-
Mishra, M.1
Durrington, P.2
Mackness, M.3
-
22
-
-
0023886723
-
Epidemiology and long-term survival in acromegaly. A study of 166 cases diagnosed between 1955 and 1984
-
Bengtsson BA, Eden S, Ernest I, et al. Epidemiology and long-term survival in acromegaly. A study of 166 cases diagnosed between 1955 and 1984. Acta Med Scand 1988; 223:327-335.
-
(1988)
Acta Med Scand
, vol.223
, pp. 327-335
-
-
Bengtsson, B.A.1
Eden, S.2
Ernest, I.3
-
24
-
-
0031774361
-
Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly
-
Swearingen B, Barker FG 2nd, Katznelson L, et al. Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly. J Clin Endocrinol Metab 1998; 83:3419-3426.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 3419-3426
-
-
Swearingen, B.1
Barker 2nd, F.G.2
Katznelson, L.3
-
25
-
-
7244257406
-
Epidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Espanol de Acromegalia, REA)
-
Mestron A, Webb SM, Astorga R, et al. Epidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Espanol de Acromegalia, REA). Eur J Endocrinol 2004; 151:439-446.
-
(2004)
Eur J Endocrinol
, vol.151
, pp. 439-446
-
-
Mestron, A.1
Webb, S.M.2
Astorga, R.3
-
27
-
-
15944401695
-
The outcome of surgery in 668 patients with acromegaly using current criteria of biochemical 'cure'. Eur
-
Nomikos P, Buchfelder M, Fahlbusch R. The outcome of surgery in 668 patients with acromegaly using current criteria of biochemical 'cure'. Eur J Endocrinol 2005; 152:379-387.
-
(2005)
J Endocrinol
, vol.152
, pp. 379-387
-
-
Nomikos, P.1
Buchfelder, M.2
Fahlbusch, R.3
-
28
-
-
0029826419
-
Outcome of transsphenoidal surgery for acromegaly using strict criteria for surgical cure
-
Sheaves R, Jenkins P, Blackburn P, et al. Outcome of transsphenoidal surgery for acromegaly using strict criteria for surgical cure. Clin Endocrinol (Oxf) 1996; 45:407-413.
-
(1996)
Clin Endocrinol (Oxf)
, vol.45
, pp. 407-413
-
-
Sheaves, R.1
Jenkins, P.2
Blackburn, P.3
-
29
-
-
0034458010
-
Long-term follow-up results of postoperative radiotherapy in 36 patients with acromegaly
-
Biermasz NR, Van Dulken H, Roelfsema F. Long-term follow-up results of postoperative radiotherapy in 36 patients with acromegaly. J Clin Endocrinol Metab 2000; 85:2476-2482.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2476-2482
-
-
Biermasz, N.R.1
Van Dulken, H.2
Roelfsema, F.3
-
30
-
-
0034455933
-
Outcome of radiotherapy for acromegaly using normalization of insulin-like growth factor I to define cure
-
Powell JS, Wardlaw SL, Post KD, Freda PU. Outcome of radiotherapy for acromegaly using normalization of insulin-like growth factor I to define cure. J Clin Endocrinol Metab 2000; 85:2068-2071.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2068-2071
-
-
Powell, J.S.1
Wardlaw, S.L.2
Post, K.D.3
Freda, P.U.4
-
31
-
-
0030884349
-
Pituitary irradiation is ineffective in normalizing plasma insulin-like growth factor I in patients with acromegaly
-
Barkan AL, Halasz I, Dornfeld KJ, et al. Pituitary irradiation is ineffective in normalizing plasma insulin-like growth factor I in patients with acromegaly. J Clin Endocrinol Metab 1997; 82:3187-3191.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3187-3191
-
-
Barkan, A.L.1
Halasz, I.2
Dornfeld, K.J.3
-
32
-
-
23844500632
-
Outcome of gamma knife radiosurgery in 82 patients with acromegaly: Correlation with initial hypersecretion
-
Castinetti F, Taieb D, Kuhn JM, et al. Outcome of gamma knife radiosurgery in 82 patients with acromegaly: correlation with initial hypersecretion. J Clin Endocrinol Metab 2005; 90:4483-4488.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 4483-4488
-
-
Castinetti, F.1
Taieb, D.2
Kuhn, J.M.3
-
33
-
-
33645989150
-
Gamma knife radiosurgery for acromegaly - long-term experience
-
Jezkova J, Marek J, Hana V, et al. Gamma knife radiosurgery for acromegaly - long-term experience. Clin Endocrinol (Oxf) 2006; 64:588-595.
-
(2006)
Clin Endocrinol (Oxf)
, vol.64
, pp. 588-595
-
-
Jezkova, J.1
Marek, J.2
Hana, V.3
-
34
-
-
34447549877
-
Efficacy and safety of CyberKnife radiosurgery for acromegaly
-
Roberts BK, Ouyang DL, Lad SP, et al. Efficacy and safety of CyberKnife radiosurgery for acromegaly. Pituitary 2007; 10:19-25.
-
(2007)
Pituitary
, vol.10
, pp. 19-25
-
-
Roberts, B.K.1
Ouyang, D.L.2
Lad, S.P.3
-
35
-
-
0031812096
-
Stereotactic radiosurgery for recurrent surgically treated acromegaly: Comparison with fractionated radiotherapy
-
Landolt AM, Haller D, Lomax N, et al. Stereotactic radiosurgery for recurrent surgically treated acromegaly: comparison with fractionated radiotherapy. J Neurosurg 1998; 88:1002-1008.
-
(1998)
J Neurosurg
, vol.88
, pp. 1002-1008
-
-
Landolt, A.M.1
Haller, D.2
Lomax, N.3
-
36
-
-
23844540615
-
Long-acting somatostatin analog therapy of acromegaly: A meta-analysis
-
Freda PU, Katznelson L, Van der Lely AJ, et al. Long-acting somatostatin analog therapy of acromegaly: a meta-analysis. J Clin Endocrinol Metab 2005; 90:4465-4473.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 4465-4473
-
-
Freda, P.U.1
Katznelson, L.2
Van der Lely, A.J.3
-
37
-
-
33748652910
-
Drug insight: Primary medical therapy of acromegaly
-
quiz following 117
-
Katznelson L. Drug insight: primary medical therapy of acromegaly. Nat Clin Pract Endocrinol Metab 2006; 2:109-117; quiz following 117.
-
(2006)
Nat Clin Pract Endocrinol Metab
, vol.2
, pp. 109-117
-
-
Katznelson, L.1
-
38
-
-
33644944535
-
-
Colao A, Pivonello R, Rosato F, et al. First-line octreotide-LAR therapy induces tumour shrinkage and controls hormone excess in patients with acromegaly: results from an open, prospective, multicentre trial. Clin Endocrinol (Oxf) 2006; 64:342-351. This study demonstrates efficacy of somatostatin analogs to improve biochemical parameters and induce tumor shrinkage as de-novo, primary therapy.
-
Colao A, Pivonello R, Rosato F, et al. First-line octreotide-LAR therapy induces tumour shrinkage and controls hormone excess in patients with acromegaly: results from an open, prospective, multicentre trial. Clin Endocrinol (Oxf) 2006; 64:342-351. This study demonstrates efficacy of somatostatin analogs to improve biochemical parameters and induce tumor shrinkage as de-novo, primary therapy.
-
-
-
-
39
-
-
23044466974
-
A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly
-
Melmed S, Sternberg R, Cook D, et al. A critical analysis of pituitary tumor shrinkage during primary medical therapy in acromegaly. J Clin Endocrinol Metab 2005; 90:4405-4410.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 4405-4410
-
-
Melmed, S.1
Sternberg, R.2
Cook, D.3
-
40
-
-
15944427116
-
Clinical review: The antitumoral effects of somatostatin analog therapy in acromegaly
-
Bevan JS. Clinical review: the antitumoral effects of somatostatin analog therapy in acromegaly. J Clin Endocrinol Metab 2005; 90:1856-1863.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 1856-1863
-
-
Bevan, J.S.1
-
41
-
-
33744954691
-
Predictors of tumor shrinkage after primary therapy with somatostatin analogs in acromegaly: A prospective study in 99 patients
-
Colao A, Pivonello R, Auriemma RS, et al. Predictors of tumor shrinkage after primary therapy with somatostatin analogs in acromegaly: a prospective study in 99 patients. J Clin Endocrinol Metab 2006; 91:2112-2118.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2112-2118
-
-
Colao, A.1
Pivonello, R.2
Auriemma, R.S.3
-
42
-
-
13244255682
-
Gross total resection or debulking of pituitary adenomas improves hormonal control of acromegaly by somatostatin analogs
-
Petrossians P, Borges-Martins L, Espinoza C, et al. Gross total resection or debulking of pituitary adenomas improves hormonal control of acromegaly by somatostatin analogs. Eur J Endocrinol 2005; 152:61-66.
-
(2005)
Eur J Endocrinol
, vol.152
, pp. 61-66
-
-
Petrossians, P.1
Borges-Martins, L.2
Espinoza, C.3
-
43
-
-
0031792509
-
Cabergoline in the treatment of acromegaly: A study in 64 patients
-
Abs R, Verhelst J, Maiter D, et al. Cabergoline in the treatment of acromegaly: a study in 64 patients. J Clin Endocrinol Metab 1998; 83:374-378.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 374-378
-
-
Abs, R.1
Verhelst, J.2
Maiter, D.3
-
44
-
-
0034690311
-
Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant
-
Trainer PJ, Drake WM, Katznelson L, et al. Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med 2000; 342:1171-1177.
-
(2000)
N Engl J Med
, vol.342
, pp. 1171-1177
-
-
Trainer, P.J.1
Drake, W.M.2
Katznelson, L.3
-
45
-
-
0035944825
-
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist
-
Van der Lely AJ, Hutson RK, Trainer PJ, et al. Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet 2001; 358:1754-1759.
-
(2001)
Lancet
, vol.358
, pp. 1754-1759
-
-
Van der Lely, A.J.1
Hutson, R.K.2
Trainer, P.J.3
-
46
-
-
33846040409
-
Gender, body weight, disease activity, and previous radiotherapy influence the response to pegvisomant
-
Parkinson C, Burman P, Messig M, Trainer PJ. Gender, body weight, disease activity, and previous radiotherapy influence the response to pegvisomant. J Clin Endocrinol Metab 2007; 92:190-195.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 190-195
-
-
Parkinson, C.1
Burman, P.2
Messig, M.3
Trainer, P.J.4
-
47
-
-
29644441517
-
Consensus statement: Medical management of acromegaly
-
Melmed S, Casanueva F, Cavagnini F, et al. Consensus statement: medical management of acromegaly. Eur J Endocrinol 2005; 153:737-740.
-
(2005)
Eur J Endocrinol
, vol.153
, pp. 737-740
-
-
Melmed, S.1
Casanueva, F.2
Cavagnini, F.3
-
48
-
-
18744389775
-
Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly
-
Feenstra J, De Herder WW, Ten Have SM, et al. Combined therapy with somatostatin analogues and weekly pegvisomant in active acromegaly. Lancet 2005; 365:1644-1646.
-
(2005)
Lancet
, vol.365
, pp. 1644-1646
-
-
Feenstra, J.1
De Herder, W.W.2
Ten Have, S.M.3
-
49
-
-
85047684868
-
Control of tumor size and disease activity during cotreatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient
-
Van der Lely AJ, Muller A, Janssen JA, et al. Control of tumor size and disease activity during cotreatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient. J Clin Endocrinol Metab 2001; 86:478-481.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 478-481
-
-
Van der Lely, A.J.1
Muller, A.2
Janssen, J.A.3
-
50
-
-
33847700931
-
Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: Safety and efficacy evaluation from the German Pegvisomant Observational Study
-
Large, multicenter follow-up for patients receiving pegvisomant. Useful for assessment of safety risks
-
Schreiber I, Buchfelder M, Droste M, et al. Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: safety and efficacy evaluation from the German Pegvisomant Observational Study. Eur J Endocrinol 2007; 156:75-82. Large, multicenter follow-up for patients receiving pegvisomant. Useful for assessment of safety risks.
-
(2007)
Eur J Endocrinol
, vol.156
, pp. 75-82
-
-
Schreiber, I.1
Buchfelder, M.2
Droste, M.3
|