Risk factors for development of coronary heart disease in patients with acromegaly: A five-year prospective study

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 11, 2007, Pages 4271-4277

  Bogazzi, Fausto ^a   Battolla, Luigi ^b   Spinelli, Cheti ^b   Rossi, Giuseppe ^c   Gavioli, Silvia ^a   Di Bello, Vitantonio ^a   Cosci, Chiara ^a   Sardella, Chiara ^a   Volterrani, Duccio ^d   Talini, Enrica ^a   Pepe, Pasquale ^c   Falaschi, Fabio ^b   Mariani, Giuliano ^d   Martino, Enio ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

^c INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^d Regional Center of Nuclear Medicine   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GROWTH HORMONE;

ACROMEGALY; ADULT; AGED; ARTICLE; COMPUTED TOMOGRAPHY SCANNER; CORONARY ARTERY; DIAGNOSTIC IMAGING; EVALUATION; FEMALE; FOLLOW UP; HIGH RISK POPULATION; HUMAN; IMAGE ANALYSIS; ISCHEMIC HEART DISEASE; ITALY; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

EID: 36048946304     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-1213     Document Type: Article

References (39)

1. Melmed S 2006 Medical progress: acromegaly. N Engl J Med 355:2558-2573
2. Colao AM, Ferone D, Marzullo P, Lombardi G 2004 Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev 25:102-152
3. Sacca' L, Cittadini A, Fazio S 1994 Growth hormone and the heart. Endocr Rev 15:555-573
4. Ciulla M, Arosio M, Barelli MV, Paliotti R, Porretti S, Valentini P, Tortora G, Buonamici V, Moraschi A, Capiello V, Magrini F 1999 Blood-pressure independent cardiac hypertrophy in acromegalic patients. J Hypert 17:1965-1969
5. Clayton RN 2003 Cardiovascular function in acromegaly. Endocr Rev 24:272-277
6. Colao AM, Marzullo P, Di Somma C, Lombardi G 2001 Growth hormone and the heart. Clin Endocrinol (Oxf) 54:137-154
7. Fazio S, Cittadini A, Cuocilo A, Merola B, Sabatini D, Colao AM, Biondi B, Lombardi G, Saccà L 1994 Impaired cardiac performance is a distinct feature of uncomplicated acromegaly. J Clin Endocrinol Metab 79:441-446
8. Minniti G, Jaffrain-Rea ML, Moroni C, Balzelli R, Ferretti E, Cassone R, Gulino A, Tamburrano G 1998 Echocardiographic evidence for a direct effect of GH/IGF-I hypersecretion on cardiac mass and function in young acromegalics. Clin Endocrinol (Oxf) 49:101-106
9. Colao AM, Marzullo P, Cuocilo A, Spinelli L, Pivonello R, Bonaduce D, Salvatore M, Lombardi G 2003 Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide. Clin Endocrinol (Oxf) 58:176-196
10. Merola B, Cittadini A, Colao AM, Ferone D, Fazio S, Sabatini D, Biondi B, Saccà L, Lombardi G 1993 Chronic treatment with the somatostatin analog octreotide improves cardiac abnormalities in acromegaly. J Clin Endocrinol Metab 77:790-793
11. Colao A, Marzullo P, Lombardi G, the Multicenter Italian Study Group on Lanreotide 2002 Effect of a six-month treatment with lanreotide on cardiovascular risk factors and arterial intima-media thickness in patients with acromegaly. Eur J Endocrinol 146:303-309
12. Bogazzi F, Di Bello V, Palagi C, Delle Donne MG, Di Cori A, Gavioli S, Talini E, Cosci C, Sardella C, Brogioni S, Mariani M, Martino E 2005 Improvement of intrinsic myocardial contractility and cardiac fibrosis degree in acromegalic patients treated with somatostatin analogues: a prospective study. Clin Endocrinol (Oxf) 62:590-596
13. Pivonello R, Galderisi M, Auriemma RS, De Martino MC, Galdiero M, Ciccarelli A, D'Errico A, Kourides I, Barman P, Lombardi G, Colao A 2007 Treatment with GH receptor antagonist in acromegaly: effect on cardiac structure and performance. J Clin Endocrinol Metab 92:476-482
14. Orme SM, McNally RJQ, Catwright RA, Belchetz PE 1998 Mortality and cancer incidence in acromegaly: a retrospective cohort study. J Clin Endocrinol Metab 83:2730-2734
15. Ayuk J, Clayton RN, Holder G, Sheppard MC, Stewart PM, Bates AS 2004 Growth hormone and pituitary radiotherapy, but not serum insulin-like growth factor-I concentrations, predict excess mortality in patients with acromegaly. J Clin Endocrinol Metab 89:1613-1617
16. Kauppinen-Makelin R, Sane T, Reunanen A, Valimaki MJ, Kiskanen L, Markkanen H, Lottyniemi E, Ebelig T, Jaatinen P, Laine H, Nuutila P, Salmela P, Salmi J, Stenman UH, Viikari J, Voutinalainen E 2005 A nationwide survey of mortality in acromegaly. J Clin Endocrinol Metab 90:4081-4086
17. Courville C, Mason VR 1938 The heart in acromegaly. Arch Intern Med 61:704-713
18. Goldberg MB, Lisser H 1942 Acromegaly: a consideration of its course and treatment. Report of four cases with autopsies. J Clin Endocrinol 2:477-501
19. Hejtmancik MR, Bradfield JY, Herrmann GR 1950 Acromegaly and heart: a clinical and pathologic study. Ann Intern Med 34:1445-1456
20. Lie JT, Grossman SJ 1980 Pathology of the heart in acromegaly: anatomic findings in 27 autopsied patients. Am Heart J 100:41-52
21. Otsuki M, Kasamaya S, Hiroyasu Y, Saito H, Sumitani S, Kouhara H, Saito Y, Ohnishi T, Arita N 2001 Characterization of premature atherosclerosis of carotid arteries in acromegalic patients. Clin Endocrinol (Oxf) 54:791-796
22. Cannavò S, Almoto B, Cavalli G, Squadrito S, Romanello G, Vigo MT, Fiumara F, Benvenga S, Trimarchi F 2006 Acromegaly and coronaric disease: an integrated evaluation of conventional coronary risk factors and coronary calcifications detected by computed tomography. J Clin Endocrinol Metab 91:3766-3772
23. Greenland P, Bonow RO, Eisenberg MJ, Grundy SM, Lauer MS, Post WS, Raggi P, Redberg RF, Rodgers GP, Shaw LJ, Taylor AJ, Weintraub WS 2007 Clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain. Circulation 115:402-426
24. Colao A, Martino E, Cappabianca P, Cozzi R, Scanarini M, Ghigo E, A.L.I.C.E. Study Group 2006 First-line therapy of acromegaly: a statement of the A.L.I.C.E. (acromegaly primary medical treatment learning and improvement with continuous medical education) Study Group. J Endocrinol Invest 29:1017-1020
25. Manetti L, Lupi I, Morselli LL, Albertini S, Cosottini M, Grasso L, Genovesi M, Pinna G, Mariotti S, Bogazzi F, Bartalena L, Martino E 2007 Prevalence and functional significance of antipituitary antibodies in patients with autoimmune and non-autoimmune thyroid diseases. J Clin Endocrinol Metab 92:2176-2181
26. Grundy SM, Cleeman JI, Merz NB, Brewer HB, Clark LT, Hunnighake DB, Pasternak RC, Smith SC, Stone NJ 2004 Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines. Circulation 110:227-239
27. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte Jr M, Detrano R 1990 Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15:827-832
28. Petronio AS, Rovai D, Musumeci G, Baglini R, Nardi C, Libruno U, Palagi C, Volterrani D, Mariani M 2003 Effects of abciximab on microvascular integrity and left ventricular functional recovery in patients with acute infarction treated by primary coronary angioplasty. Eur Heart J 24:67-76
29. Delafontaine P, Lou H, Alexander RW 1991 Regulation of insulin-like growth factor 1 messenger RNA levels in vascular smooth muscle cells. Hypertension 18:742-747
30. Budoff MJ, Achebach S, Blumenthal RS, Carr JJ, Goldin JG, Greenland P, Guerci AD, Lima JAC, Rader DJ, Rubin GD, Shaw LJ, Wiegers SE 2006 Assessment of coronary artery disease by cardiac computed tomography: a statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation 114:1761-1791
31. Rumberger JA, Simons DB, Fitzpatrick LA, Sheedy PF, Schwartz RS 1995 Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation 92:2157-2162
32. Arad Y, Goodman KJ, Roth M, Newstein D, Guerci AD 2005 Coronary calcification, coronary disease risk factor, C-reactive protein, and atherosclerotic cardiovascular disease event: the St. Francis Heart Study. J Am Coll Cardiol 46:158-165
33. Greenland P, LaBree L, Azen SP, Doherty TM, Detrano RC 2004 Coronary artery calcium score combined with Framinghan score for risk prediction in asymptomatic individuals. JAMA 291:210-215
34. Redberg RF, Vogel RA, Criqui MH, Herrington DM, Lima JA, Roman MJ 2003 34th Bethesda Conference: Task force #3-What is the spectrum of current and emerging techniques for the noninvasive measurement of atherosclerosis? J Am Coll Cardiol 41:1886-1898
35. Third report of the National Cholesterol Education Program (NCEP) 2002 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 106:3143-3421
36. Herrmann BL, Brandt-Mainz K, Saller B, Bruch C, Wieneke H, Kugler C, Ferdin S, Hahn S, Erbel R, Bockisch A, Mann K 2003 Myocardial perfusion abnormalities in patients with active acromegaly. Horm Metab Res 35:183-188
37. Kapur A, Latus KA, Davies G, Dhawan RT, Eastick S, Jarritt PH, Roussakis G, Young MC, Anagnostopoulos C, Bomanji J, Costa DC, Pennell DJ, Prvulovich EM, Ell PJ, Underwood SR 2002 A comparison of three radionuclide myocardial perfusion tracers in clinical practice: the ROBUST study. Eur J Nucl Med Mol Imaging 29:1608-1616
38. Taillefer R, DePuey EG, Udelson JE, Beller GA, Latour Y, Reeves F 1997 Comparative diagnostic accuracy of Tl-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECG-gated SPECT) in detecting coronary artery disease in women. J Am Coll Cardiol 29:69-77
39. Metz LD, Beattie M, Hom R, Redberg RF, Grady D, Fleischmann KE 2007 The prognostic value of normal exercise myocardial perfusion imaging and exercise echocardiography: a meta-analysis. J Am Coll Cardiol 49:227-237