Monoamine transporters in human endometrium and decidua

Human Reproduction Update

Volumn 15, Issue 2, 2009, Pages 249-260

  Hansson, Stefan R ^a   Bottalico, Barbara ^a   Noskova, Vera ^a   Casslén, Bertil ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Decidua; Endometrium; Histamine; Monoamines

Indexed keywords

ADRENALIN; AMINE OXIDASE (FLAVIN CONTAINING); CARRIER PROTEIN; CATECHOL METHYLTRANSFERASE; DOPAMINE; DOPAMINE TRANSPORTER; HISTAMINE; INDOLEAMINE; MONOAMINE; NEURONAL MONOAMINE TRANSPORTER; NEUROTRANSMITTER; NON NEURONAL MONOAMINE TRANSPORTER; NORADRENALIN; NORADRENALIN TRANSPORTER; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; SEROTONIN; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER; VESICULAR MONOAMINE TRANSPORTER 1; VESICULAR MONOAMINE TRANSPORTER 2;

CAPILLARY PERMEABILITY; CELL FATE; CELL VACUOLE; CONCENTRATION (PARAMETERS); DECIDUA; DECIDUALIZATION; ENDOMETRIUM; ENZYME INACTIVATION; FEMALE; FEMALE INFERTILITY; HUMAN; IMMUNOMODULATION; INFERTILITY THERAPY; INFLAMMATION; MEDLINE; MENSTRUATION; MONOAMINE METABOLISM; MONOAMINERGIC SYSTEM; NIDATION; PREGNANCY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN SECRETION; REPRODUCTION; REVIEW; UTERUS BLOOD FLOW;

BIOGENIC MONOAMINES; DECIDUA; EMBRYO IMPLANTATION; ENDOMETRIUM; EPITHELIAL CELLS; EQUILIBRATIVE NUCLEOSIDE TRANSPORT PROTEINS; FEMALE; HUMANS; ORGANIC CATION TRANSPORT PROTEINS; PLACENTATION; PREGNANCY; REPRODUCTION; RNA, MESSENGER; STROMAL CELLS; SUBSTRATE SPECIFICITY; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 60149092745     PISSN: 13554786     EISSN: 14602369     Source Type: Journal    
DOI: 10.1093/humupd/dmn048     Document Type: Review

References (116)

1. Alm P, Falck B, Owman C, Sjöberg NO, Thorbert G. Reduced level of uterine norepinephrine transmitter during hCG-induced pseudopregrancy in the rabbit. Endocrinology 1975;96:819-822.
2. Amara SG, Kuhar MJ. Neurotransmitter transporters: Recent progress. Annu Rev Neurosci 1993;16:73-93.
3. Amenta F, Vega JA, Ricci A, Collier WL. Localization of 5-hydroxytryptamine-like immunoreactive cells and nerve fibers in the rat female reproductive system. Anat Rec 1992;233:478-484.
4. Apparsundaram S, Moore KR, Malone MD, Hartzell CH, Blakely RD. Molecular cloning and characterization of an L-epinephrine transporter from sympathetic ganglia of the bullfrog, Rana catesbiana. J Neurosci 1997;17:2691-2702.
5. Axelrod J. Brain monoamines. Biosynthesis and fate. Neurosci Res Program Bull 1971;9:188-196.
6. Balkovetz DF, Tiruppathi C, Leibach FH, Mahesh VB, Ganapathy V. Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes. J Biol Chem 1989;264:2195-2198.
7. Barash A, Dekel N, Fieldust S, Segal I, Schechtman E, Granot I. Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization. Fertil Steril 2003;79: 1317-1322.
8. Barkai U, Kraicer PF. Intrauterine signaling and embryonic implantation. Biol Signals 1996;5:111-121.
9. Battaglia G, Cabrera T, Van de Kar LD. Prenatal cocaine produces biochemical and functional changes in brain serotonin systems in rat progeny. NIDA Res Monogr 1995;158:115-148.
10. Baxter SW, Thomas EJ, Campbell IG. GSTM I null polymorphism and susceptibility to endometriosis and ovarian cancer. Carcinogenesis 2001;22:63-65.
11. Beer DJ, Matloff SM, Rocklin RE. The influence of histamine on immune and inflammatory responses. Adv Immunol 1984;35:209-268.
12. Blakely RD, Berson HE, Fremeau RT Jr, Caron MG, Peek MM, Prince HK, Bradley CC. Cloning and expression of a functional serotonin transporter from rat brain. Nature 1991;354:66-70.
13. Borowsky B, Hoffman BJ. Neurotransmitter transporters: Molecular biology, function, and regulation. Int Rev Neurobiol 1995;38 139-199.
14. Bottalico B, Pilka R, Larsson I, Casslen B, Marsal K, Hansson S. Plasma membrane and vesicular monoamine transporters in normal endometrium and early pregnancy decidua. Mol Hum Reprod 2003;9: 389-394.
15. Bottalico B, Larsson I, Casslen B, Broszki J, Hernandez-Andrade E, Marsal K, Hansson RS. Norepinephrine (NET), serotonin (SERT), vesicular monoamine (VMAT2) and organic cation transporters (OCT1,2 and EMT) in human placenta from preeclamptic and normotensive pregnancies. Placenta 2004;25:518-529.
16. Bottalico B, Noskova V, Pilka R, Larsson I, Domanski H, Casslen B, Hansson SR. The organic cation transporters (OCT1, OCT2, EMT) and the plasma membrane monoamine transporter (PMAT) show differential distribution and cyclic expression pattern in human endometrium and early pregnancy decidua. Mol Reprod Dev 2007; 74:1303-1311.
17. Bradley DJ, Towle HC, Young WS III. Spatial and temporal expression of α- and β-thyroid hormone receptor mRNAs, including the β2-Subtype, in the developing mammalian nervous system. J Neurosci 1992;12: 2288-2302.
18. Brownstein MJ, Hoffman BJ. Neurotransmitter transporters. Recent Prog Horm Res 1994;49:27-42.
19. Brownstein MJ, Saavedra JM, Palkovits M, Axelrod J. Histamine content of hypothalamic nuclei of the rat. Brain Res 1974;77:151-156.
20. Buznikov GA. The action of neurotransmitters and related substances on early embryogenesis. Pharmacol Ther 1984;25:23-59.
21. Casslen B, Kobayashi TK, Stormby N. Cyclic variation of the cellular components in human uterine fluid. J Reprod Fertil 1982: 66 213-218.
22. Chang AS, Chang SM, Starnes DM, Schroeter S, Bauman AL, Blakely RD. Cloning and expression of the mouse serotonin transporter. Brain Res Mol Brain Res 1996;43:185-192.
23. Cocchiara R, Di Trapani G, Azzolina A, Albeggiani G, Geraci D. Early embryonic histamine-releasing factor: A new model for human implantation. Hum Reprod 1986;1:445-447.
24. Declercq de Perez Bedes G, Garcia Bienere W. Retention of noradrenaline by the rat endometrial epithelium. Action of estradiol. Ann Endocrinol (Paris) 1975;36:185-187.
25. Demir R, Kosanke G, Kohnen G, Kertschanska S, Kaufmann P. Classification of human placental stem villi: Review of structural and functional aspects. Microsc Res Tech 1997;38:29-41.
26. Dey SK. Role of histamine in implantation: Inhibition of histidine decarboxylase induced delayed implantation in the rabbit. Biol Reprod 1981;24:867-869.
27. Dey SK, Villanueva C, Abdou NI. Histamine receptors on rabbit blastocyst and endometrial cell membranes. Nature 1979;278:648-649.
28. Eisenhofer G. The role of neuronal and extraneuronal plasma membrane transporters in the activation of peripheral catecholamines. Pharmacol Ther 2001;91:35-62.
29. Eisenhofer G, Kopin IJ, Goldstein DS. Catecholamine metabolism: A contemporary view with implications for physiology and medicine. Pharmacol Rev 2004;56:331-349.
30. Engel K, Wang J. Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Mol Pharmacol 2005; 68 1397-1407.
31. Engel K, Zhou M, Wang J. Identification and characterization of a novel monoamine transporter in the human brain. J Biol Chem 2004;279 50042-50049.
32. Erickson JD, Eiden LE. Functional identification and molecular cloning of a human brain vesicle monoamine transporter. J Neurochem 1993;61: 2314-2317.
33. Erickson JD, Eiden LE, Hoffman BJ. Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc Natl Acad Sci USA 1992;89:10993-10997.
34. Erickson JD, Schafer MK, Bonner TI, Eiden LE, Weihe E. Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter. Proc Natl Acad Sci USA 1996;93:5166-5171.
35. Foley KF, DeSanty KP, Kast RE. Bupropion: Pharmacology and therapeutic applications. Expert Rev Neurother 2006;6:1249-1265.
36. Fox K. The critical period for long-term potentiation in primary sensory cortex. Neuron 1995;15:485-488.
37. Ganapathy V, Leibach FH. Placental biogenic amines and their transporters. In: Ramasastry BV (ed). Placental Toxicology. Boca Raton, FL: CRC, 1995,161-174.
38. Ganapathy V, Ramamoorthy S, Leibach FH. Transport and metabolism of monoamines in the human placenta. Trophoblast Res 1993;7 35-51.
39. Godfrey KM. The role of the placenta in fetal programming - a review. Placenta 2002;23(Suppl A):S20-S27.
40. Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, Baumann C, Lang F, Busch AE, Koepsell H. Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol 1997;16:871-881.
41. Grundemann D, Schechinger B, Rappold GA, Schomig E. Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter. Nat Neurosci 1998;1:349-351.
42. Grundemann D, Liebich G, Kiefer N, Koste S, Schomig E. Selective substrates for non-neuronal monoamine transporters. Mol Pharmacol 1999;56:1-10.
43. Hansson SR, Mezey E, Hoffman BJ. Serotonin transporter mRNA expression in neuronal crest-derived structures and sensory pathways of the developing rat embryo. Neuroscience 1998;89:243-265.
44. Hansson S, Bottalico B, Amer-Wahlin I, Marsal K, Ley D. Increased fetal blood pressure response to maternal norepinephrine after pharmacological inhibition of norepinephrine uptake in pregnant sheep. Acta Paediatr 2007;96:650-654.
45. Hatanaka K, Kitamura Y, Maeyama K, Watanabe T, Matsumoto K. Deciduoma formation in uterus of genetically mast cell-deficient W/W mice. Biol Reprod 1982;27:25-28.
46. Hayer-Zillgen M, Bruss M, Bonisch H. Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3. Br J Pharmacol 2002;136:829-836.
47. Hendrickson MR, Kempson RL. Surgical Pathology of the Uterine Corpus Philadelphia: Saunders, 1980.
48. Hobel CJ, Parvez H, Parvez S, Lirette M, Papiernik E. Enzymes for epinephrine synthesis and metabolism in the myometrium, endometrium, red blood cells, and plasma of pregnant human subjects. Am J Obstet Gynecol 1981;141:1009-1018.
49. Hoffman BJ. Expression cloning of a serotonin transporter: A new way to study antidepressant drugs. Pharmacopsychiatry 1994;27:16-22.
50. Hoffman LH, Winfrey VP, Hoos PC. Sites of endometrial vascular leakage during implantation in the rabbit. Anat Rec 1990;227:47-61.
51. Hoffman BJ, Mezey E, Brownstein MJ. Cloning of a serotonin transporter affected by antidepressants. Science 1991;254:579-580.
52. Iversen LL. The uptake of catecholamine at high perfusion concentrations in the rat isolated heart: A novel catecholamine uptake process. Br J Pharmacol 1965;25:18-33.
53. Jeffrey JJ, Ehlich LS, Roswit WT. Serotonin: An inducer of collagenase in myometrial smooth muscle cells. J Cell Physiol 1991;146 399-406.
54. Johnson DC, Dey SK. Role of histamine in implantation: Dexamethasone inhibits estradiol-induced implantation in the rat. Biol Reprod 1980;22: 1136-1141.
55. Kandel ER, Schwartz JH. In: Kandel ER, Schwartz JH (eds). Principles of Neural Science. New York: Elsevier, 1985.
56. Kennedy JA, de la Lande IS. Effect of progesterone on the metabolism of noradrenaline in rabbit uterine endometrium and myometrium. Naunyn Schmiedebergs Arch Pharmacol 1986;333:368-376.
57. Kilty JE, Lorang D, Amara SG. Cloning and expression of a cocaine-sensitive rat dopamine transporter. Science 1991;254 578-579.
58. Koehler MR, Wissinger B, Gorboulev V, Koepsell H, Schmid M. The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26. Cytogenet Cell Genet 1997;79: 198-200.
59. Koepsell H. Polyspecific organic cation transporters: Their functions and interactions with drugs. Trends Pharmacol Sci 2004;25 375-381.
60. Lang U, Prada J, Clark KE. Systemic and uterine vascular response to serotonin in third trimester pregnant ewes. Eur J Obstet Gynecol Reprod Biol 1993;51:131-138.
61. Laporte R, DeRoth L. Modulation of the effects of norepinephrine uptake inhibitors on the norepinephrine-induced contractile response of the porcine uterine artery during early pregnancy. Can J Vet Res 1997;61: 214-220.
62. Leslie CA, Robertson MW, Jung AB, Liebermann J, Bennett JP Jr. Effects of prenatal cocaine exposure upon postnatal development of neostriatal dopaminergic function. Synapse 1994;17:210-215.
63. Liu Z, Kilburn BA, Leach RE, Romero R, Paria BC, Armant DR. Histamine enhances cytotrophoblast invasion by inducing intracellular calcium transients through the histamine type-1 receptor. Mol Reprod Dev 2004;68:345-353.
64. Maekawa F, Yamanouchi K. Effect of deprivation of serotonin by pchlorophenylalanine on induction and maintenance of pseudopregnancy in female rats. Brain Res Bull 1996;39:317-321.
65. Manyonda IT, Fenske C, Hole D, Choy MY, Wilson C. A role for noradrenaline in pre-eclampsia: Towards a unifying hypothesis for the pathophysiology. Br J Obstet Gynaecol 1998;105:641-648.
66. Marshak DR. S100 beta as a neurotrophic factor. Prog Brain Res 1990;86: 169-181.
67. Matsuzawa-Yanagida K, Narita M, Nakajima M, Kuzumaki N, Niikura K, Nozaki H, Takagi T, Tamai E, Hareyama N, Terada M et al. Usefulness of antidepressants for improving the neuropathic pain-like state and pain-induced anxiety through actions at different brain sites. Neuropsychopharmacology 2008;33:1952-1965.
68. Merickel A, Edwards RH. Transport of histamine by vesicular monoamine transporter-2. Neuropharmacology 1995;34:1543-1547.
69. Meyer JS, Shearman LP, Collins LM, Maguire RL. Cocaine binding sites in fetal rat brain: Implications for prenatal cocaine action. Psychopharmacology (Berl) 1993;112:445-451.
70. Mezey E, Eisenhofer G, Harta G, Hansson S, Gould L, Hunyady B, Hoffman BJ. A novel nonneuronal catecholaminergic system: Exocrine pancreas synthesizes and releases dopamine. Proc Natl Acad Sci USA 1996; 93: 10377-10382.
71. Mitchell JA, Hammer RE, Goldman H. Serotonin-induced disruption of implantation in the rat: II. Suppression of decidualization. Biol Reprod 1983;29:151-156.
72. Moiseiwitsch JR, Lauder JM. Serotonin regulates mouse cranial neural crest migration. Proc Natl Acad Sci USA 1995;92:7182-7186.
73. Nirenberg MJ, Liu Y, Peter D, Edwards RH, Pickel VM. The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei. Proc Natl Acad Sci USA 1995;92:8773-8777.
74. Noskova V, Bottalico B, Orbona I, Pilka R, Larsson I, Casslen B, Marsal K, Hansson SR. Histamine uptake by organic cation transporter (EMT) and vesicular monoamine transporter (VMAT2) in cultured human endometrial stromal and epithelial cells. Mol Hum Reprod 2006;12: 483-489.
75. Noyes RW, Hertig AT, Rock J. Dating the endometrial biopsy. Fertil Steril 1950;1:3-25.
76. Olson L, Seiger A. Early prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations. Z Anat Entwicklungsgesch 1972;137:301-316.
77. Olson L, Boreus LO, Seiger A. Histochemical demonstration and mapping of 5-hydroxytryptamine- and catecholamine-containing neuron systems in the human fetal brain. Z Anat Entwicklungsgesch 1973;139: 259-282.
78. Pacholczyk T, Blakely RD, Amara SG. Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 1991; 350:350-354.
79. Paria BC, Das N, Das SK, Zhao X, Dileepan KN, Dey SK. Histidine decarboxylase gene in the mouse uterus is regulated by progesterone and correlates with uterine differentiation for blastocyst implantation. Endocrinology 1998;139:3958-3966.
80. Paria BC, Lim H, Das SK, Reese J, Dey SK. Molecular signaling in uterine receptivity for implantation. Semin Cell Dev Biol 2000;11 67-76.
81. Pastuszak A, Schick-Boschetto B, Zuber C, Feldkamp M, Pinelli M, Sihn S, Donnenfeld A, McCormack M, Leen-Mitchell M, Woodland C et al. Pregnancy outcome following first-trimester exposure to Fluoxetine (Prozac). JAMA 1993;269:2246-2248.
82. Pedroza-Garcia E, Garcia Bienere W, Inglesi J, Szerezewski A, Rosner JM. Interactions in the uptake between catecholamines and estradiol in the human uterus. Am J Obstet Gynecol 1975;122:96-100.
83. Peter D, Liu Y, Brecha N, Edwards RH. The transport of neurotransmitters into synaptic vesicles. Prog Brain Res 1995a; 105:273-281.
84. Peter D, Liu Y, Sternini C, de Giorgio R, Brecha N, Edwards RH. Differential expression of two vesicular monoamine transporters. J Neurosci 1995b; 15:6179-6188.
85. Pilka R, Noskova V, Domanski H, Andersson C, Hansson S, Casslen B. Endometrial TIMP-4 mRNA is expressed in the stroma, while TIMP-4 protein accumulates in the epithelium and is released to the uterine fluid. Mol Hum Reprod 2006;12:497-503.
86. Poropatich C, Rojas M, Silverberg SG. Polymorphonuclear leukocytes in the endometrium during the normal menstrual cycle. Int J Gynecol Pathol 1987;6:230-234.
87. Prasad PD, Leibach FH, Mahesh VB, Ganapathy V. Human placenta as a target organ for cocaine action: Interaction of cocaine with the placental serotonin transporter. Placenta 1994;15:267-278.
88. Ramamoorthy S, Bauman AL, Moore KR, Han H, Yang-Feng T, Chang AS, Ganapathy V, Blakely RD. Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization. Proc Natl Acad Sci USA 1993a;90:2542-2546.
89. Ramamoorthy S, Prasad PD, Kulanthaivel P, Leibach FH, Blakely RD, Ganapathy V. Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast. Biochemistry 1993b;32:1346-1353.
90. Rockwell LC, Pillai S, Olson CE, Koos RD. Inhibition of vascular endothelial growth factor/vascular permeability factor action blocks estrogen-induced uterine edema and implantation in rodents. Biol Reprod 2002; 67:1804-1810.
91. Schrey MP, Hare AL, Ilson SL, Walters MP. Decidual histamine release and amplification of prostaglandin F2 alpha production by histamine in interleukin-1 beta-primed decidual cells: Potential interactive role for inflammatory mediators in uterine function at term. J Clin Endocrinol Metab 1995;80:648-653.
92. Schroeter S, Levey AI, Blakely RD. Polarized expression of the antidepressant-sensitive serotonin transporter in epinephrine-synthesizing chromaffin cells of the rat adrenal gland. Mol Cell Neurosci 1997;9: 170-184.
93. Schuldiner S, Liu Y, Edwards RH. Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts. J Biol Chem 1993;268:29-34.
94. Shah NR, Jones JB, Aperi J, Shemtov R, Karne A, Borenstein J. Selective serotonin reuptake inhibitors for premenstrual syndrome and premenstrual dysphoric disorder: A meta-analysis. Obstet Gynecol 2008; 111 1175-1182.
95. Shelesnyak MC. Inhibition of decidual cell formation in the pseudopregnant rat by histamine antagonists. Am J Physiol 1952; 170:522-527.
96. Shelesnyak MC. Some experimental studies on the mechanism of ova-implantation in the rat. Recent Prog Horm Res 1957;13 269-322.
97. Shiverick KT, Salafia C. Cigarette smoking and pregnancy I: Ovarian, uterine and placental effects. Placenta 1999;20:265-272.
98. Skarzynski DJ, Uenoyama Y, Kotwica J, Okuda K. Noradrenaline stimulates the production of prostaglandin f2alpha in cultured bovine endometrial cells. Biol Reprod 1999;60:277-282.
99. Steinbusch HWM, Mulder AH. Immunohistochemical localization of histamine in neurons and mast cells in the rat brain. In: Bjorklund A, Hokfelt T, Kuhar MJ (eds). Handbook of Chemical Anatomy, Vol 3: Classical Transmitters and Transmitter Receptors in the CNS, Part 11. London: Elsevier Science, 1984,126-140.
100. Talvenheimo J, Rudnick G. Solubilization of the platelet plasma membrane serotonin transporter in an active form. J Biol Chem 1980;255 8606-8611.
101. Tatsumi M, Groshan K, Blakely RD, Richelson E. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol 1997;340:249-258.
102. Torres GE, Gainetdinov RR, Caron MG. Plasma membrane monoamine transporters: Structure, regulation and function. Nat Rev Neurosci 2003; 4:13-25.
103. Uhl GR, Kitayama S. A cloned dopamine transporter. Potential insights into Parkinson's disease pathogenesis. Adv Neurol 1993;60 321-324.
104. Usdin TB, Mezey E, Chen C, Brownstein MJ, Hoffman BJ. Cloning of the cocaine-sensitive bovine dopamine transporter. Proc Natl Acad Sci USA 1991;88:11168-11171.
105. Wade PR, Chen J, Jaffe B, Kassem IS, Blakely RD, Gershon MD. Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. J Neurosci 1996;16:2352-2364.
106. Weihe E, Schafer MK, Erickson JD, Eiden LE. Localization of vesicular monoamine transporter isoforms (VMAT1 and VMAT2) to endocrine cells and neurons in rat. J Mol Neurosci 1994;5:149-164.
107. Whitaker-Azmitia PM, Druse M, Walker P, Lauder JM. Serotonin as a developmental signal. Behav Brain Res 1996;73:19-29.
108. Whitaker-Azmitia PM, Shemer AV, Caruso J, Molino L, Azmitia EC. Role of high affinity serotonin receptors in neuronal growth. Ann NY Acad Sci 1990;600:315-330.
109. 3-Norepinephrine in animals. J Pharmacol Exp Ther 1961;132:193-201.
110. White MV. The role of histamine in allergic diseases. J Allergy Clin Immunol 1990;86:599-605.
111. Wieland A, Hayer-Zillgen M, Bonisch H, Bruss M. Analysis of the gene structure of the human (SLC22A3) and murine (Slc22a3) extraneuronal monoamine transporter. J Neural Transm 2000;107:1149-1157.
112. Wilcox BD, Rydelek-Fitzgerald L, Jeffrey JJ. Regulation of collagenase gene expression by serotonin and progesterone in rat uterine smooth muscle cells. J Biol Chem 1992;267:20752-20757.
113. Woods JR. Maternal and transplacental effects of cocaine. Ann N Y Acad Sci 1998;846:1-11.
114. Yanagawa T, Kishimoto Y, Tada K, Arai F, Kondo Y, Kudo T. Presence of dopamine DA-1 receptors in human decidua. Placenta 1997;18 169-172.
115. Zhang L, Dresser MJ, Gray AT, Yost SC, Terashita S, Giacomini KM. Cloning and functional expression of a human liver organic cation transporter. Mol Pharmacol 1997;51:913-921.
116. Zhao X, Ma W, Das SK, Dey SK, Paria BC. Blastocyst H(2) receptor is the target for uterine histamine in implantation in the mouse. Development 2000;127:2643-2651.