TaxlBPl interacts with papillomavirus E2 and regulates E2-dependent transcription and stability

Journal of Virology

Volumn 83, Issue 5, 2009, Pages 2274-2284

  Wang, Xiaoyu ^a   Naidu, Samisubbu R ^a   Sverdrup, Francis ^a,c   Androphy, Elliot J ^a,b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GLYCOPROTEIN E2; PROTEIN P300; PROTEIN TAX1BP1; UNCLASSIFIED DRUG; VIRUS PROTEIN; DNA BINDING PROTEIN; E2 PROTEIN, BOVINE PAPILLOMAVIRUS; E2 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOPROTEIN; PROTEASOME; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TAX1BP1 PROTEIN, HUMAN; TUMOR PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; NONHUMAN; PAPILLOMA VIRUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; TRANSCRIPTION REGULATION; TWO HYBRID SYSTEM; VIRUS GENOME; YEAST; ANIMAL; BOVINE PAPILLOMAVIRUS TYPE 1; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HELA CELL; HUMAN PAPILLOMAVIRUS TYPE 11; METABOLISM; MOUSE; PROTEIN STABILITY; UBIQUITINATION;

BOVINE PAPILLOMAVIRUS TYPE 1; HUMAN PAPILLOMAVIRUS TYPE 18; PAPILLOMAVIRIDAE;

ANIMALS; BOVINE PAPILLOMAVIRUS 1; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, VIRAL; HELA CELLS; HUMAN PAPILLOMAVIRUS 11; HUMAN PAPILLOMAVIRUS 18; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NEOPLASM PROTEINS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITINATION; VIRAL PROTEINS;

EID: 60049094359     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01791-08     Document Type: Article

References (47)

1. Androphy, E. J., D. R. Lowy, and J. T. Schiller. 1987. Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA. Nature 325:70-73.
2. Bellanger, S., C. Demeret, S. Goyat, and F. Thierry. 2001. Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domain. J. Virol. 75:7244-7251.
3. Breiding, D. E., M. J. Grossel, and E. J. Androphy. 1996. Genetic analysis of the bovine papillomavirus E2 transcriptional activation domain. Virology 221:34-43.
4. Chin, K. T., A. C. Chun, Y. P. Ching, K. T. Jeang, and D. Y. Jin. 2007. Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1. Cancer Res. 67:1072-1081.
5. Crosas, B., J. Hanna, D. S. Kirkpatrick, D. P. Zhang, Y. Tone, N. A. Hathaway, C. Buecker, D. S. Leggett, M. Schmidt, R. W. King, S. P. Gygi, and D. Finley. 2006. Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. Cell 127:1401-1413.
6. De Valck, D., D. Y. Jin, K. Heyninck, M. Van de Craen, R. Contreras, W. Fiers, K. T. Jeang, and R. Beyaert. 1999. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene 18:4182-4190.
7. Giandomenico, V., M. Simonsson, E. Gronroos, and J. Ericsson. 2003. Co-activator-dependent acetylation stabilizes members of the SREBP family of transcription factors. Mol. Cell. Biol. 23:2587-2599.
8. Giri, I., and M. Yaniv. 1988. Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains. EMBO J. 7:2823-2829.
9. Gregory, M. A., and S. R. Hann. 2000. c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells. Mol. Cell. Biol. 20:2423-2435.
10. Gronroos, E., U. Hellman, C. H. Heldin, and J. Ericsson. 2002. Control of Smad7 stability by competition between acetylation and ubiquitination. Mol. Cell 10:483-493.
11. Grossman, S. R., M. E. Deato, C. Brignone, H. M. Chan, A. L. Kung, H. Tagami, Y. Nakatani, and D. M. Livingston. 2003. Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science 300:342-344.
12. Grossman, S. R., M. Perez, A. L. Kung, M. Joseph, C. Mansur, Z. X. Xiao, S. Kumar, P. M. Howley, and D. M. Livingston. 1998. p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol. Cell 2:405-415.
13. Grussenmeyer, T., K. H. Scheidtmann, M. A. Hutchinson, W. Eckhart, and G. Walter. 1985. Complexes of polyoma virus medium T antigen and cellular proteins. Proc. Natl. Acad. Sci. USA 82:7952-7954.
14. Gu, W., and R. G. Roeder. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90:595-606.
15. Haugen, T. H., L. P. Turek, F. M. Mercurio, T. P. Cripe, B. J. Olson, R. D. Anderson, D. Seidl, M. Karin, and J. Schiller. 1988. Sequence-specific and general transcriptional activation by the bovine papillomavirus-1 E2 trans-activator require an N-terminal amphipathic helix-containing E2 domain. EMBO J. 7:4245-4253.
16. Iha, H., J. M. Peloponese, L. Verstrepen, G. Zapart, F. Ikeda, C. D. Smith, M. F. Starost, V. Yedavalli, K. Heyninck, I. Dikic, R. Beyaert, and K. T. Jeang. 2008. Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kB activation. EMBO J. 27:629-641.
17. Ito, A., Y. Kawaguchi, C. H. Lai, J. J. Kovacs, Y. Higashimoto, E. Appella, and T. P. Yao. 2002. MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J. 21:6236-6245.
18. Ito, A., C. H. Lai, X. Zhao, S. Saito, M. H. Hamilton, E. Appella, and T. P. Yao. 2001. p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J. 20:1331-1340.
19. Kruppel, U., A. Muller-Schiffmann, S. E. Baldus, S. Smola-Hess, and G. Steger. 2008. E2 and the co-activator p300 can cooperate in activation of the human papillomavirus type 16 early promoter. Virology 377:151-159.
20. Kumar, R. A., S. R. Naidu, X. Wang, A. N. Imbalzano, and E. J. Androphy. 2007. Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation. J. Virol. 81:2213-2220.
21. Lambert, P. F., B. A. Spalholz, and P. M. Howley. 1987. A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell 50:69-78.
22. Lassot, I., E. Estrabaud, S. Emiliani, M. Benkirane, R. Benarous, and F. Margottin-Goguet. 2005. p300 modulates ATF4 stability and transcriptional activity independently of its acetyltransferase domain. J. Biol. Chem. 280: 41537-41545.
23. Lee, D., S. G. Hwang, J. Kim, and J. Choe. 2002. Functional interaction between p/CAF and human papillomavirus E2 protein. J. Biol. Chem. 277: 6483-6489.
24. Lee, D., B. Lee, J. Kim, D. W. Kim, and J. Choe. 2000. cAMP response element-binding protein-binding protein binds to human papillomavirus E2 protein and activates E2-dependent transcription. J. Biol. Chem. 275:7045-7051.
25. Lehman, C. W., D. S. King, and M. R. Botchan. 1997. A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention. J. Virol. 71: 3652-3665.
26. Li, M., J. Luo, C. L. Brooks, and W. Gu. 2002. Acetylation of p53 inhibits its ubiquitination by Mdm2. J. Biol. Chem. 277:50607-50611.
27. Li, R., J. Knight, G. Bream, A. Stenlund, and M. Botchan. 1989. Specific recognition nucleotides and their DNA context determine the affinity of E2 protein for 17 binding sites in the BPV-1 genome. Genes Dev. 3:510-526.
28. Ling, L., and D. V. Goeddel. 2000. T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proc. Natl. Acad. Sci. USA 97:9567-9572.
29. Lusky, M., and E. Fontane. 1991. Formation of the complex of bovine papillomavirus E1 and E2 proteins is modulated by E2 phosphorylation and depends upon sequences within the carboxyl terminus of E1. Proc. Natl. Acad. Sci. USA 88:6363-6367.
30. Martinez-Balbas, M. A., U. M. Bauer, S. J. Nielsen, A. Brehm, and T. Kouzarides. 2000. Regulation of E2F1 activity by acetylation. EMBO J. 19:662-671.
31. McBride, A. A., J. C. Byrne, and P. M. Howley. 1989. E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc. Natl. Acad. Sci. USA 86:510-514.
32. McBride, A. A., H. Romanczuk, and P. M. Howley. 1991. The papillomavirus E2 regulatory proteins. J. Biol. Chem. 266:18411-18414.
33. Muller, A., A. Ritzkowsky, and G. Steger. 2002. Cooperative activation of human papillomavirus type 8 gene expression by the E2 protein and the cellular coactivator p300. J. Virol. 76:11042-11053.
34. Niman, H. L., R. A. Houghten, L. E. Walker, R. A. Reisfeld, I. A. Wilson, J. M. Hogle, and R. A. Lerner. 1983. Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. Proc. Natl. Acad. Sci. USA 80:4949-4953.
35. Pearson, M., R. Carbone, C. Sebastiani, M. Cioce, M. Fagioli, S. Saito, Y. Higashimoto, E. Appella, S. Minucci, P. P. Pandolfi, and P. G. Pelicci. 2000. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature 406:207-210.
36. Peng, Y. C., D. E. Breiding, F. Sverdrup, J. Richard, and E. J. Androphy. 2000. AMF-1/Gps2 binds p300 and enhances its interaction with papilloma-virus E2 proteins. J. Virol. 74:5872-5879.
37. Penrose, K. J., and A. A. McBride. 2000. Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number. J. Virol. 74:6031-6038.
38. Rehtanz, M., H. M. Schmidt, U. Warthorst, and G. Steger. 2004. Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription. Mol. Cell. Biol. 24:2153-2168.
39. Shembade, N., N. S. Harhaj, D. J. Liebl, and E. W. Harhaj. 2007. Essential role for TAX1BP1 in the termination of TNF-α-, IL-1- and LPS-mediated NF-KB and JNK signaling. EMBO J. 26:3910-3922.
40. Shembade, N., N. S. Harhaj, K. Parvatiyar, N. G. Copeland, N. A. Jenkins, L. E. Matesic, and E. W. Harhaj. 2008. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nat. Immunol. 9:254-262.
41. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
42. Simonsson, M., C. H. Heldin, J. Ericsson, and E. Gronroos. 2005. The balance between acetylation and deacetylation controls Smad7 stability. J. Biol. Chem. 280:21797-21803.
43. Sverdrup, F., and S. A. Khan. 1994. Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins. J. Virol. 68:505-509.
44. Yao, J. M., D. E. Breiding, and E. J. Androphy. 1998. Functional interaction of the bovine papillomavirus E2 transactivation domain with TFIIB. J. Virol. 72:1013-1019.
45. You, J., J. L. Croyle, A. Nishimura, K. Ozato, and P. M. Howley. 2004. Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell 117:349-360.
46. Yu, T., Y. C. Peng, and E. J. Androphy. 2007. Mitotic kinesin-like protein 2 binds and colocalizes with papillomavirus E2 during mitosis. J. Virol. 81: 1736-1745.
47. Zeng, S. X., Y. Jin, D. T. Kuninger, P. Rotwein, and H. Lu. 2003. The acetylase activity of p300 is dispensable for MDM2 stabilization. J. Biol. Chem. 278:7453-7458.