Abnormal assemblies and subunit exchange of αB-crystallin R120 mutants could be associated with destabilization of the dimeric substructure

Biochemistry

Volumn 48, Issue 2, 2009, Pages 442-453

  Michiel, Magalie ^a   Skouri Panet, Fériel ^b   Duprat, Elodie ^a   Simon, Stéphanie ^c   Férard, Céline ^b   Tardieu, Annette ^a   Finet, Stéphanie ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^c CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LIGHT SCATTERING; MOLECULAR DYNAMICS; SIMULATED ANNEALING; STRUCTURAL DYNAMICS; X RAY SCATTERING;

ANION EXCHANGE CHROMATOGRAPHY; CHAPERONE-LIKE ACTIVITY; INCREASING TEMPERATURES; INTERSUBUNIT INTERACTION; QUATERNARY STRUCTURE; SMALL HEAT SHOCK PROTEINS; STATIC AND DYNAMIC LIGHT SCATTERING; TEMPERATURE AND PRESSURES;

SIZE EXCLUSION CHROMATOGRAPHY;

ALPHA CRYSTALLIN; ARGININE; DIMER; MUTANT PROTEIN; OLIGOMER; PROTEIN SUBUNIT; SMALL HEAT SHOCK PROTEIN;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; GEL PERMEATION CHROMATOGRAPHY; LIGHT SCATTERING; MOLECULAR DYNAMICS; MOLECULAR SIZE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN QUATERNARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; SIMULATION; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMISTRY; COMPUTER SIMULATION; DIMERIZATION; ESCHERICHIA COLI; GEL CHROMATOGRAPHY; GENETICS; HUMAN; HYDROGEN BOND; ION EXCHANGE CHROMATOGRAPHY; LIGHT; METABOLISM; MOLECULAR GENETICS; MOLECULAR WEIGHT; MUTATION; NUCLEOTIDE SEQUENCE; PRESSURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; SMALL ANGLE SCATTERING; STRUCTURE ACTIVITY RELATION; TEMPERATURE;

ALPHA-CRYSTALLIN B CHAIN; AMINO ACID SEQUENCE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; COMPUTER SIMULATION; CONSERVED SEQUENCE; DIMERIZATION; ESCHERICHIA COLI; HUMANS; HYDROGEN BONDING; LIGHT; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTAGENESIS, SITE-DIRECTED; MUTATION; PRESSURE; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 59849129128     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8014967     Document Type: Article

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