Editorial: Cyclooxygenase-2-derived prostaglandin F2α: An endothelium-derived contractile factor acting independently of other endothelium-derived contractile factors via vascular thromboxane receptors

Circulation Research

Volumn 104, Issue 2, 2009, Pages 141-143

  Schrör, Karsten ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

EDCF; Hamster aorta; PGF2 ; Thromboxane receptors

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ENDOTHELIUM DERIVED CONSTRICTING FACTOR; PROSTAGLANDIN F2 ALPHA; THROMBOXANE RECEPTOR; CALCIUM; PTGS2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

AORTA CONSTRICTION; EDITORIAL; ENZYME SYNTHESIS; FEMORAL ARTERY; HYPERTENSION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION; VASOMOTOR REFLEX; ANIMAL; DRUG EFFECT; HUMAN; METABOLISM; NOTE; VASCULAR ENDOTHELIUM;

ANIMALS; CALCIUM; CYCLOOXYGENASE 2; DINOPROST; ENDOTHELIUM, VASCULAR; HUMANS; REACTIVE OXYGEN SPECIES; RECEPTORS, THROMBOXANE; SIGNAL TRANSDUCTION; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 59849126844     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.192526     Document Type: Editorial

References (23)

1. Vanhoutte PM, Tang EHC. Endothelium-dependent contractions: when a good guy turns bad. J Physiol. 2008;586:5295-5304.
2. Taddei S, Virdis S, Mattei P, Ghiadoni L, Fasolo CB, Sudano I, Sakvetti A. Hypertension causes premature aging of endothelial function in humans. Hypertension. 1997;29:736-743.
3. Matsumoto T, Kakami M, Noguchi E, Kobayashi T, Kamata K. Imbalance between endothelium-derived relaxing and contractile factors in mesenteric arteries from aged OLETF rats, a model of type 2 diabetes. Am J Physiol Heart Circ Physiol. 2007;293:H1480-H1490.
4. Tokunaga O, Yamada T, Fan J, Watanabe T. Age-related decline in prostacyclin biosynthesis by human aortic endothelial cells. Am J Pathol. 1991;138:141-149.
5. Lennon EA, Poyser NL. Effect of age on vascular prostaglandin production in male and female rats. Prostagl Leukotr Med. 1986;25:1-15.
6. Shi Y, Man RYK, Vanhoutte PM. Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats. Acta Pharmacol Sin. 2008;29:185-192.
7. Tang EHC, Vanhoutte PM. Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension. Physiol Genomics. 2008; 32:409-418.
8. Auch-Schwelk W, Katusic ZS, Vanhoutte PM. Thromboxane A2 receptor antagonists inhibit endothelium-dependent contractions. Hypertension. 1990;15:699-703.
9. Gluais P, Lonchampt M, Morrow JD, Vanhoutte PM, Feletou M. Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin. Br J Pharmacol. 2005;146: 834-845.
10. Wong SL, Leung FP, Lau CW, Au CL, Yung LM, Yao X, Chen Z-Y, Vanhoutte PM, Gollasch M, Huang Y. Cyclooxygenase-2-derived prostaglandin F2a mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res. 2009;104:228-235.
11. Hirao A, Kondo K, Takeuchi K, Inui N, Umemura K, Ohashi K, Watanabe H. Cyclooxygenase-dependent vaoconstricting factor(s) in remodelled rat femoral arteries. Cardiovasc Res. 2008;79:161-168.
12. DeWitt DL, Day JS, Sonnenburg WK, Smith WL. Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta. J Clin Invest. 1983;72: 1882-1888.
13. Ge T, Hughes H, Junquero DC, Wu KK, Vanhoutte PM, Boulanger CM. Endothelium-dependent contractions are associated with both augmented expression of prostaglandin H synthase-1 and hypersensitivity to prostaglandin H2 in the SHR aorta. Circ Res. 1995;76:1003-1010.
14. McAdam BF, Catella-Lawson F, Mardini IA, Kapoor S, Lawson JA, FitzGerald GA. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2-the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci USA. 1999;96:272-277.
15. Halushka PV, Allan CJ, Davis-Bruno KL. Thromboxane A2 receptors. J Lipid Med Cell Signal. 1995;12:361-378.
16. Sametz W, Hennerbichler S, Glaser S, Wintersteiger R, Juan H. Characterization of prostanoid receptors mediating action of the isoprostanes, 8-iso-PGE2 and 8-iso-PGF2a, in some isolated smooth muscle preparations. Br J Pharmacol. 2000;130:1903-1910.
17. Armstrong RA, Wilson NH. Aspects of the thromboxane receptor system. Gen Pharmac. 1995;26:463-472.
18. Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ. Cyclooxygen-ase-1 and-2-dependent prostacyclin formation in patients with atherosclerosis. Circulation. 2000;102:840-845.
19. Tang EHC, Jensen BL, Skott O, Leung GPH, Feletou M, Man RYK, Vanhoutte PM. The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats. Cardiovasc Res. 2008;78: 130-138.
20. Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvien TK, Schnitzer TJ; VIGOR Study Group. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Engl J Med. 2000;343:1520-1528.
21. Lüscher TF, Boulanger CM, Yang Z, Noll G, Dohi Y. Interactions between endothelium-derived relaxing and contracting factors in health and cardiovascular disease. Circulation. 1993;87(suppl V):V-36-V-44.
22. Egg D, Herold M, Rumpl E, Gunther R. Prostaglandin F2a levels in human cerebrospinal fluid in normal and pathological conditions. J Neurol. 1980;222:239-248.
23. Behm DJ, Ogbonna A, Wu C, Burns-Kurtis CL, Douglas SA. Epoxyeicoatrieneoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation. J Pharmacol Exp Ther. 2009;328:231-239.