A rational approach to predict and modulate stereolability of chiral α substituted ketones

Chirality

Volumn 21, Issue 1, 2009, Pages 24-34

  Cirilli, Roberto ^a   Costi, Roberta ^b   Di Santo, Roberto ^b   Gasparrini, Francesco ^b   La Torre, Francesco ^a   Pierini, Marco ^b   Siani, Gabriella ^c  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF CHIETI   (Italy)

Author keywords

Asymmetric synthesis; Chemical design; Enantiomerization; Enolization; Keto enol tautomerism; MAO inhibitors; Molecular modeling; Racemization

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); KETONE; PROTON; WATER; ACETONITRILE; ACETONITRILE DERIVATIVE; CARBON; HYDROGEN; MONOAMINE OXIDASE INHIBITOR; PYRROLIDINE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; ATOM; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CHIRALITY; CIRCULAR DICHROISM; ENANTIOMER; ENANTIOSELECTIVITY; KINETICS; MEASUREMENT; MOLECULAR MODEL; POLARIMETRY; PRIORITY JOURNAL; THERMODYNAMICS; CHEMISTRY; STEREOISOMERISM;

ACETONITRILES; CARBON; HYDROGEN; KETONES; KINETICS; MODELS, MOLECULAR; MONOAMINE OXIDASE INHIBITORS; PYRROLIDINES; STEREOISOMERISM; THERMODYNAMICS; WATER;

EID: 59849121710     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20589     Document Type: Article

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