Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors

Journal of Medicinal Chemistry

Volumn 48, Issue 13, 2005, Pages 4220-4223

  Di Santo, Roberto ^a   Costi, Roberta ^a   Roux, Alessandra ^a   Artico, Marino ^a   Befani, Olivia ^a   Meninno, Tiziana ^a   Agostinelli, Enzo ^a   Palmegiani, Paola ^a   Turini, Paola ^a   Cirilli, Roberto ^b   Ferretti, Rosella ^b   Gallinella, Bruno ^b   La Torre, Francesco ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; AMINOALCOHOL; AMINOKETONE; MOCLOBEMIDE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; MONOAMINE OXIDASE INHIBITOR; PYRROLYLETHANONEAMINE DERIVATIVE; SELEGILINE; TOLOXATONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; COW; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; LIPOPHILICITY; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MONOAMINE OXIDASE INHIBITORS; OXAZOLIDINONES; PIPERAZINES; PIPERIDINES; PYRROLIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 21244505103     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050172c     Document Type: Article

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