CCL2 DNA vaccine to treat renal disease

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 4, 2009, Pages 729-732

  Watson, Debbie ^a   Zheng, Guoping ^b   Wu, Huiling ^c   Wang, Yuan Min ^a   Wang, Yiping ^b   Harris, David C H ^b   Alexander, S I ^a  

^a CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Adriamycin nephropathy; Chemokine; DNA vaccine; Immune response; Monocyte chemoattractant protein 1

Indexed keywords

AUTOANTIBODY; DNA VACCINE; DOXORUBICIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES;

ADJUVANT ARTHRITIS; AUTOIMMUNITY; CELLULAR IMMUNITY; DNA STRUCTURE; DRUG STRUCTURE; HUMAN; KIDNEY DISEASE; MACROPHAGE; NONHUMAN; PROTEIN EXPRESSION; SHORT SURVEY; TH1 CELL;

AMINO ACID SEQUENCE; ANIMALS; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; HUMANS; KIDNEY DISEASES; MOLECULAR SEQUENCE DATA; RATS; VACCINES, DNA;

RATTUS;

EID: 59849097571     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.04.028     Document Type: Short Survey

References (20)

1. Fujinaka H., Yamamoto T., Takeya M., Feng L., Kawasaki K., Yaoita E., et al. Suppression of anti-glomerular basement membrane nephritis by administration of anti-monocyte chemoattractant protein-1 antibody in WKY rats. J Am Soc Nephrol 8 (1997) 1174-1178
2. Furuichi K., Wada T., Iwata Y., Kitagawa K., Kobayashi K., Hashimoto H., et al. Gene therapy expressing amino-terminal truncated monocyte chemoattractant protein-1 prevents renal ischemia-reperfusion injury. J Am Soc Nephrol 14 (2003) 1066-1071
3. Hertz M., Mahalingam S., Dalum I., Klysner S., Mattes J., Neisig A., et al. Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma. J Immunol 167 (2001) 3792-3799
4. Donnelly J.J., Wahren B., and Liu M.A. DNA vaccines: progress and challenges. J Immunol. 175 2 (2005) 633-639
5. Kunkel S.L., and Godessart N. Chemokines in autoimmunity: from pathology to therapeutics. Autoimmun Rev 1 (2002) 313-320
6. Rangan G.K., Wang Y., Tay Y.C., and Harris D.C. Cytokine gene expression in adriamycin nephropathy: effects of antioxidant nuclear factor kappaB inhibitors in established disease. Nephron 86 (2000) 482-490
7. Segerer S., Nelson P.J., and Schlondorff D. Chemokines, chemokine receptors, and renal disease: from basic science to pathophysiologic and therapeutic studies. J Am Soc Nephrol 11 (2000) 152-176
8. Shimizu H., Maruyama S., Yuzawa Y., Kato T., Miki Y., Suzuki S., et al. Anti-monocyte chemoattractant protein-1 gene therapy attenuates renal injury induced by protein-overload proteinuria. J Am Soc Nephrol 14 (2003) 1496-1505
9. Shimizu S., Nakashima H., Masutani K., Inoue Y., Miyake K., Akahoshi M., et al. Anti-monocyte chemoattractant protein-1 gene therapy attenuates nephritis in MRL/lpr mice. Rheumatology (Oxford) 43 (2004) 1121-1128
10. Tesch G.H. MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy. Am J Physiol Renal Physiol (2008)
11. Tesch G.H., Maifert S., Schwarting A., Rollins B.J., and Kelley V.R. Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas(lpr) mice. J Exp Med 190 (1999) 1813-1824
12. Tesch G.H., Schwarting A., Kinoshita K., Lan H.Y., Rollins B.J., and Kelley V.R. Monocyte chemoattractant protein-1 promotes macrophage-mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis. J Clin Invest 103 (1999) 73-80
13. Wang Y., Chen J., Chen L., Tay Y.C., Rangan G.K., and Harris D.C. Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein. J Am Soc Nephrol 8 (1997) 1537-1545
14. Wang Y., Rangan G.K., Goodwin B., Tay Y.C., and Harris D.C. Lipopolysaccharide-induced MCP-1 gene expression in rat tubular epithelial cells is nuclear factor-kappaB dependent. Kidney Int 57 (2000) 2011-2022
15. Wenzel U., Schneider A., Valente A.J., Abboud H.E., Thaiss F., Helmchen U.M., et al. Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis. Kidney Int 51 (1997) 770-776
16. Wildbaum G., Youssef S., and Karin N. A targeted DNA vaccine augments the natural immune response to self TNF-alpha and suppresses ongoing adjuvant arthritis. J Immunol 165 (2000) 5860-5866
17. Wu H., Wang Y., Tay Y.C., Zheng G., Zhang C., Alexander S.I., et al. DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. Kidney Int 67 (2005) 2178-2186
18. Youssef S., Wildbaum G., Maor G., Lanir N., Gour-Lavie A., Grabie N., et al. Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines. J Immunol 161 (1998) 3870-3879
19. Youssef S., Maor G., Wildbaum G., Grabie N., Gour-Lavie A., and Karin N. C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis. J Clin Invest 106 (2000) 361-371
20. Zheng G., Wang Y., Xiang S.H., Tay Y.C., Wu H., Watson D., et al. DNA vaccination with CCL2 DNA modified by the addition of an adjuvant epitope protects against "nonimmune" toxic renal injury. J Am Soc Nephrol 17 (2006) 465-474