The cyclopentenone 15-deoxy-δ12,14-prostaglandin J 2 delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse

Endocrinology

Volumn 150, Issue 2, 2009, Pages 699-706

  Pirianov, Grisha ^a   Waddington, Simon N ^b   Lindström, Tamsin M ^a   Terzidou, Vasiliki ^a   Mehmet, Huseyin ^a   Bennett, Phillip R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; CYCLOPENTENONE 15 DEOXY DELTA 12,14 PROSTAGLANDIN J2; CYTOSOLIC PHOSPHOLIPASE A2; LIPOPOLYSACCHARIDE; PROSTAGLANDIN J2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FETUS MORTALITY; IN VITRO STUDY; MOUSE; MYOMETRIUM; NONHUMAN; PREGNANCY OUTCOME; PREMATURE LABOR; PRIORITY JOURNAL; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANIMALS, OUTBRED STRAINS; ANTI-INFLAMMATORY AGENTS; CYCLOPENTANES; DRUG EVALUATION, PRECLINICAL; FEMALE; INFLAMMATION; LIPOPOLYSACCHARIDES; MYOMETRIUM; NF-KAPPA B; OBSTETRIC LABOR, PREMATURE; PHOSPHOLIPASES A2; PHOSPHORYLATION; PREGNANCY; PROSTAGLANDIN D2; TIME FACTORS; UTERINE DISEASES; UTERUS;

EID: 59749094580     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1178     Document Type: Article

References (47)

1. Wen SW, Smith G, Yang Q, Walker M 2004 Epidemiology of preterm birth and neonatal outcome. Semin Fetal Neonatal Med 9:429-435
2. Dyet LE, Kennea N, Counsell SJ, Maalouf EF, Ajayi-Obe M, Duggan PJ, Harrison M, Allsop JM, Hajnal J, Herlihy AH, Edwards B, Laroche S, Cowan FM, Rutherford MA, Edwards AD 2006 Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessment. Pediatrics 118:536-548
3. Hagberg B, Hagberg G, Beckung E, Uvebrant P 2001 Changing panorama of cerebral palsy in Sweden. VIII. Prevalence and origin in the birth year period 1991-94. Acta Paediatr 90:271-277
4. Romero R, Espinoza J, Mazor M, Chaiworapongsa T 2004 The preterm parturition syndrome. In: Critchley H, Bennett P, Thornton S, eds. Preterm birth. London: RCOG Press; 28
5. Romero R, Mazor M 1988 Infection and preterm labor. Clin Obstet Gynecol 31:553-584
6. ElovitzMA,WangZ,ChienEK,RychlikDF,PhillippeM2003Anewmodel for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4. Am J Pathol 163:2103-2111
7. Wu YW, Colford Jr JM 2000 Chorioamnionitis as a risk factor for cerebral palsy: a meta-analysis. JAMA 284:1417-1424
8. Debillon T, Gras-Leguen C, Véerielle V, Winer N, Caillon J, Rozé JC, Gressens P2000 Intrauterine infection induces programmed cell death in rabbit periventricular white matter. Pediatr Res 47:736 -742
9. Drougia A, Giapros V, Krallis N, Theocharis P, Nikaki A, Tzoufi M, Andronikou S 2007 Incidence and risk factors for cerebral palsy in infants with perinatal problems: a 15-year review. Early Hum Dev 83:541-547
10. Wang H, Hirsch E 2003 Bacterially induced preterm labor and regulation of prostaglandin-metabolizing enzyme expression in mice: the role of toll-like receptor 4. Biol Reprod 69:1957-1963
11. Fitzgerald KA, Rowe DC, GolenbockDT2004 Endotoxin recognition and signal transduction by the TLR4/MD2-complex. Microbes Infect 6:1361-1367
12. Elovitz MA, Mrinalini C, Sammel MD 2006 Elucidating the early signal transduction pathways leading to fetal brain injury in preterm birth. Pediatr Res 59:50-55
13. Romero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel LA, Nien JK 2006 Inflammation in preterm and term labour and delivery. Semin Fetal Neonatal Med 11:317-326
14. Pollard JK, Mitchell MD 1996 Intrauterine infection and the effects of inflamatory mediators on prostaglandin production by myometrial cells from pregnant women. Am J Obstet Gynecol 174:682-686
15. Gravett MG, Witkin SS, Haluska GJ, Edwards JL, Cook MJ, Novy MJ 1994 An experimental model for intraamniotic infection and preterm labor in rhesus monkeys. Am J Obstet Gynecol 171:1660 -1667
16. Kelly RW 2002 Inflammatory mediators and cervical ripening. JReprod Immunol 57:217-224
17. Baggia S, Gravett MG, Witkin SS, Haluska GJ, Novy MJ 1996 Interleukin-1 β intraamniotic infusion induces tumor necrosis factor-α, prostaglandin production, and preterm contractions in pregnant rhesus monkeys. J Soc Gynecol Investig 3:121-126
18. Bell MJ, Hallenbeck JM, Gallo V 2004 Determining the fetal inflammatory response in an experimental model of intrauter ineinflammation in rats.Pediatr Res 56:541-546
19. Mendelson CR, Condon JC 2005 New insights into the molecular endocrinology of parturition. J Steroid Biochem Mol Biol 93:113-119
20. Choi SJ, Oh SY, Kim JH, Roh CR 2007 Changes of nuclear factor κB(NF-κB), cyclooxygenase-2(COX-2) and matrix metalloproteinase- 9(MMP-9) in human myometrium before and during term labor. Eur J Obstet Gynecol Reprod Biol 132:182-188
21. Condon JC, Hardy DB, Kovaric K, Mendelson CR 2006 Up-regulation of the progesterone receptor(PR)-C isoform in laboring myometrium by activation of nuclear factor-κB may contribute to the onset of labor through inhibition of PR function. Mol Endocrinol 20:764-775
22. Belt AR, Baldassare JJ, Molnar M, Romero R, Hertelendy F 1999 The nuclear transcription factor NF-κB mediates interleukin-1β-induced expression of cyclooxygenase-2 in human myometrial cells. Am JObstet Gynecol 181:359-366
23. Slater D, AllportV, Bennett P 1998 Changes in the expression of the type-2 but not the type-1 cycloxygenase enzyme in chorion-decidua with the onset of labour. BrJObstetGynaecol105:745-748
24. Filipovich Y, Lu S-J, Hirsch E, E. coli induced preterm delivery in the mouse is completely dependent upon the Toll-like receptor adaptor protein MyD88. Proc 54th Annual Meeting of the Society for Gynecologic Investigation, Reproductive Sciences, 2007, Reno, NV, p 131A(Abstract 265)
25. Lappas M, Permezel M, Georgiou HM, Rice GE 2002 Nuclear factor κB regulation of proinflammatory cytokines in human gestational tissues in vitro. Biol Reprod 67:668 -673
26. Lindstrom TM, Bennett PR 2005 15-Deoxy-A12,14-prostaglandin J2 inhibits IL-1β-induced NF-κB in human amnion and myometrial cells: mechanisms and implications. J Clin Endocrinol Metab 90:3534-3543
27. Lappas M, Permezel M, Rice GE 2006 15-Deoxy-A(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues. Placenta 27:1060 -1072
28. Hirsch E, Saotome I, Hirsh D 1995 A model of intrauterine infection and preterm delivery in mice. Am JObstet Gynecol 172:1598-1603
29. Buss H, Dorrie A, Schmitz ML, Hoffmann E, Resch K, Kracht M 2004Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase(IKK)-α, IKKβ, IKKε, TRAF family member-associated(TANK)- binding kinase 1(TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31- mediated interleukin-8 transcription. J Biol Chem 279:55633-55643
30. Vichai V, Suyarnsesthakorn C, Pittayakhajonwut D, Sriklung K, Kirtikara K 2005 PositivefeedbackregulationofCOX-2 expression by prostaglandin metabolites. Inflamm Res 54:163-172
31. Tsubouchi Y, Kawahito Y, Kohno M, Inoue K, Hla T, Sano H 2001 Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy(12,14)-prostaglandin J2. Biochem Biophys Res Commun 18;283:750-755
32. Romero R, Sirtori M, Oyarzun E, Avila C, Mazor M, Callahan R, Sabo V, Athanassiadis AP, Hobbins JC 1989 Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 161:817-824
33. Jiang Z, Georgel P, Du X, Shamel L, Sovath S, Mudd S, Huber M, Kalis C, Keck S, Galanos C, Freudenberg M, Beutler B 2005 CD14 is required for MyD88- independent LPS signaling. Nat Immunol 6:565-570
34. Huber M, Kalis C, Keck S, Jiang Z, George lP, Du X, Shame lL, Sovath S, Mudd S, Beutler B, Galanos C, Freudenberg MA 2006 R-form LPS, the master key to the activation ofTLR4/MD-2-positive cells. Eur J Immunol 36:701-711
35. Cuzzocrea S, Wayman NS, Mazzon E, Dugo L, Di Paola R, Serraino I, Britti D, Chatterjee PK, Caputi AP, Thiemermann C 2002Thecyclopentenoneprostaglandin 15-deoxy-δ(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. Mol Pharmacol 61:997-1007
36. Gilroy DW, Colville-Nash PR, Willis D, Chivers J, Paul-Clark MJ, Willoughby DA 1999 Inducible cyclooxygenase may have anti-inflammatory properties. Nat Med 5:698-701
37. Norwitz ER, Starkey PM, Lopez Bernal A 1992 Prostaglandin D2 production by term human decidua: cellular origins defined using flow cytometry. Obstet Gynecol 80:440-445
38. Helliwell RJ, Keelan JA, Marvin KW, Adams L, Chang MC, Anand A, Sato TA, O'Carroll S, Chaiworapongsa T, Romero RJ, Mitchell MD 2006 Gestational age-dependent up-regulation of prostaglandin D synthase(PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta. J Clin Endocrinol Metab 91:597-606
39. Berry EB, Keelan JA, Helliwell RJ, Gilmour RS, Mitchell MD 2005 Nanomolar andmicromolareffectsof15-deoxy-δ12,14-prostaglandinJ2onamnion- derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors γa and δ and nuclear factor κB. Mol Pharmacol 68:169-178
40. Ackerman WE 4th, Zhang XL, Rovin BH, Kniss DA 2005 Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFκB signal disruption in human WISH and amnion cells. Biol Reprod 73:527-535
41. KudoI,MurakamiM2002PhospholipaseA2enzymes.ProstaglandinsOther Lipid Mediat 68-69:3-58
42. Diamond AK, SweetL M, Oppenheimer KH, Bradley DF, Phillippe M 2007 Modulation of monocyte chemotactic protein-1 expression during lipopolysaccharide- induced preterm delivery in the pregnant mouse. Reprod Sci 14:548 -559
43. Esplin MS, Peltier MR, Hamblin S, Smith S, Fausett MB, Dildy GA, Branch DW, Silver RM, Adashi EY 2005 Monocytechemotacticprotein-1 expression is increased in human gestational tissues during term and preterm labor. Placenta 26:661-671
44. LeeJ G, Lee SH, Park DW, Lee SH, Yoon HS, Chin BR, Kim JH, Kim JR, Baek SH 2008 Toll-likereceptor9-stimulatedmonocytechemoattractantprotein-1 is mediated via JNK-cytosolic phospholipase A2-ROS signaling. Cell Signal 20:105-111
45. Wolter S, Doerrie A, Weber A, Schneider H, Hoffmann E, vonder Ohe J, Bakiri L, Wagner EF, Resch K, Kracht M 2008 c-Jun controls histone modifications, NF-kB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol 28:4407-4423
46. Parl AK, Rice VM, Khabele D 2007 Keratinocyte chemoattractant(KC)/ hu- man growth-regulated oncogene(GRO) chemokines and proinflammatory chemokine networks in mouse and human ovarian epithelial cancer cells. Cancer Biol Ther 6:1302-1312
47. Monneret G, Li H, Vasilescu J, Rokach J, Powell WS 2002 15-Deoxy-A12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. J Immunol 168:3563-3569