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Volumn 37, Issue 3, 2009, Pages 357-366

Proteasome proteolytic profile is linked to Bcr-Abl expression

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; IMATINIB; PROTEASOME; PROTEASOME INHIBITOR; SMALL INTERFERING RNA;

EID: 59749086449     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2008.11.004     Document Type: Article
Times cited : (13)

References (53)
  • 1
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo T.G., Pendergast A.M., Muller A.J., and Witte O.N. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 247 (1990) 1079-1082
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 2
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • Druker B.J., Guilhot F., O'Brien S.G., et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 355 (2006) 2408-2417
    • (2006) N Engl J Med , vol.355 , pp. 2408-2417
    • Druker, B.J.1    Guilhot, F.2    O'Brien, S.G.3
  • 3
    • 33745102555 scopus 로고    scopus 로고
    • Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
    • Talpaz M., Shah N.P., Kantarjian H., et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 354 (2006) 2531-2541
    • (2006) N Engl J Med , vol.354 , pp. 2531-2541
    • Talpaz, M.1    Shah, N.P.2    Kantarjian, H.3
  • 4
    • 0032539702 scopus 로고    scopus 로고
    • Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids
    • Adams J., Behnke M., Chen S., et al. Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids. Bioorg Med Chem Lett 8 (1998) 333-338
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 333-338
    • Adams, J.1    Behnke, M.2    Chen, S.3
  • 5
    • 0033152760 scopus 로고    scopus 로고
    • Proteasome inhibitors: a novel class of potent and effective antitumor agents
    • Adams J., Palombella V.J., Sausville E.A., et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 59 (1999) 2615-2622
    • (1999) Cancer Res , vol.59 , pp. 2615-2622
    • Adams, J.1    Palombella, V.J.2    Sausville, E.A.3
  • 8
    • 0033564512 scopus 로고    scopus 로고
    • Eponemycin exerts it antitumour effect through inhibition of proteasome function
    • Meng L., Kwok B.H., Sin N., and Crews C.M. Eponemycin exerts it antitumour effect through inhibition of proteasome function. Cancer Res 59 (1999) 2798-2801
    • (1999) Cancer Res , vol.59 , pp. 2798-2801
    • Meng, L.1    Kwok, B.H.2    Sin, N.3    Crews, C.M.4
  • 9
    • 0032189685 scopus 로고    scopus 로고
    • Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor
    • Orlowski R.Z., Eswara J.R., Lafond-Walker A., Grever M.R., Orlowski M., and Dang C.V. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res 58 (1998) 4342-4348
    • (1998) Cancer Res , vol.58 , pp. 4342-4348
    • Orlowski, R.Z.1    Eswara, J.R.2    Lafond-Walker, A.3    Grever, M.R.4    Orlowski, M.5    Dang, C.V.6
  • 10
    • 3042562304 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts
    • Nawrocki S.T., Sweeeny-Gotsch B., Takamori R., and McConkey D.J. The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther 3 (2004) 59-70
    • (2004) Mol Cancer Ther , vol.3 , pp. 59-70
    • Nawrocki, S.T.1    Sweeeny-Gotsch, B.2    Takamori, R.3    McConkey, D.J.4
  • 11
    • 33744832401 scopus 로고    scopus 로고
    • United States Food and Drug Administration approval summary: bortezomib for the treatment of progressive multiple myeloma after one prior therapy
    • Kane R.C., Farell A.T., Sridhara R., and Pazdur R. United States Food and Drug Administration approval summary: bortezomib for the treatment of progressive multiple myeloma after one prior therapy. Clin Cancer Res 12 (2006) 2955-2960
    • (2006) Clin Cancer Res , vol.12 , pp. 2955-2960
    • Kane, R.C.1    Farell, A.T.2    Sridhara, R.3    Pazdur, R.4
  • 12
    • 33747875167 scopus 로고    scopus 로고
    • Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia
    • Faderl S., Rai K., Gribben J., et al. Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia. Cancer 107 (2006) 916-924
    • (2006) Cancer , vol.107 , pp. 916-924
    • Faderl, S.1    Rai, K.2    Gribben, J.3
  • 13
    • 34848870352 scopus 로고    scopus 로고
    • Bortezomib for the treatment of mantle cell lymphoma
    • Kane R.C., Dagher R., Farell A., et al. Bortezomib for the treatment of mantle cell lymphoma. Clin Cancer Res 13 (2007) 5291-5294
    • (2007) Clin Cancer Res , vol.13 , pp. 5291-5294
    • Kane, R.C.1    Dagher, R.2    Farell, A.3
  • 14
    • 34249088967 scopus 로고    scopus 로고
    • Efficacy and safety of Bortezomib in patients with plasma cell leukemia
    • Musto P., Rossini F., Gay F., et al. Efficacy and safety of Bortezomib in patients with plasma cell leukemia. Cancer 109 (2007) 2285-2290
    • (2007) Cancer , vol.109 , pp. 2285-2290
    • Musto, P.1    Rossini, F.2    Gay, F.3
  • 15
    • 41949135751 scopus 로고    scopus 로고
    • Response of primary plasma cell leukemia to the combination of bortezomib and dexamethasone: do specific cytogenetic and immunophenotypic characteristics influence treatment outcome?
    • Katodritou E., Verrou E., Gastari V., Hadjiaggelidou C., Terpos E., and Zervas K. Response of primary plasma cell leukemia to the combination of bortezomib and dexamethasone: do specific cytogenetic and immunophenotypic characteristics influence treatment outcome?. Leuk Res 32 (2008) 1153-1156
    • (2008) Leuk Res , vol.32 , pp. 1153-1156
    • Katodritou, E.1    Verrou, E.2    Gastari, V.3    Hadjiaggelidou, C.4    Terpos, E.5    Zervas, K.6
  • 16
    • 40949128188 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia
    • Attar E.C., Deangelo D.J., Supko J.G., et al. Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia. Clin Cancer Res 14 (2008) 1446-1454
    • (2008) Clin Cancer Res , vol.14 , pp. 1446-1454
    • Attar, E.C.1    Deangelo, D.J.2    Supko, J.G.3
  • 17
    • 0037059012 scopus 로고    scopus 로고
    • Preferential induction of apoptosis for primary human leukemic stem cells
    • Guzman M.L., Swiderski C.F., Howard D.F., et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proc Natl Acad Sci U S A 99 (2002) 16220-16225
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16220-16225
    • Guzman, M.L.1    Swiderski, C.F.2    Howard, D.F.3
  • 18
    • 0242493856 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571
    • Yu C., Rahmani M., Conrad D., Subler M., Dent P., and Grant S. The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571. Blood 102 (2003) 3765-3774
    • (2003) Blood , vol.102 , pp. 3765-3774
    • Yu, C.1    Rahmani, M.2    Conrad, D.3    Subler, M.4    Dent, P.5    Grant, S.6
  • 19
    • 3142554015 scopus 로고    scopus 로고
    • Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms
    • Dai Y., Rahmani M., Pei X.Y., Dent P., and Grant S. Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms. Blood 104 (2004) 509-518
    • (2004) Blood , vol.104 , pp. 509-518
    • Dai, Y.1    Rahmani, M.2    Pei, X.Y.3    Dent, P.4    Grant, S.5
  • 20
    • 30144443664 scopus 로고    scopus 로고
    • The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism
    • Dasmahapatra G., Rahmani M., Dent P., and Grant S. The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism. Blood 107 (2006) 232-240
    • (2006) Blood , vol.107 , pp. 232-240
    • Dasmahapatra, G.1    Rahmani, M.2    Dent, P.3    Grant, S.4
  • 21
    • 10444224552 scopus 로고    scopus 로고
    • Proteasome proteolytic activity in hematopoietic cells from patients with chronic myeloid leukemia and multiple myeloma
    • Magill L., Lynas J., Morris T.C., Walker B., and Irvine A.E. Proteasome proteolytic activity in hematopoietic cells from patients with chronic myeloid leukemia and multiple myeloma. Hematalogica 89 (2004) 1428-1433
    • (2004) Hematalogica , vol.89 , pp. 1428-1433
    • Magill, L.1    Lynas, J.2    Morris, T.C.3    Walker, B.4    Irvine, A.E.5
  • 22
    • 0030774890 scopus 로고    scopus 로고
    • The active sites of the eukaryotic 20S proteasome and their involvement in subunit precursor processing
    • Heinemeyer W., Fischer M., Krimmer T., Stachon U., and Wolf D.H. The active sites of the eukaryotic 20S proteasome and their involvement in subunit precursor processing. J Biol Chem 272 (1997) 25200-25209
    • (1997) J Biol Chem , vol.272 , pp. 25200-25209
    • Heinemeyer, W.1    Fischer, M.2    Krimmer, T.3    Stachon, U.4    Wolf, D.H.5
  • 23
    • 0027708384 scopus 로고
    • Catalytic components of the bovine pituitary multicatalytic proteinase complex (proteasome)
    • Cardozo C. Catalytic components of the bovine pituitary multicatalytic proteinase complex (proteasome). Enzyme Protein 47 (1993) 296-301
    • (1993) Enzyme Protein , vol.47 , pp. 296-301
    • Cardozo, C.1
  • 24
    • 0033197542 scopus 로고    scopus 로고
    • Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown
    • Kisselev A.F., Akopian T.N., Castillo V., and Goldberg A.L. Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown. Mol Cell 4 (1999) 395-402
    • (1999) Mol Cell , vol.4 , pp. 395-402
    • Kisselev, A.F.1    Akopian, T.N.2    Castillo, V.3    Goldberg, A.L.4
  • 25
    • 0040008534 scopus 로고    scopus 로고
    • Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function
    • Jager S., Groll M., Huber R., Wolf D.H., and Heinemeyer W. Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function. J Mol Biol 291 (1999) 997-1013
    • (1999) J Mol Biol , vol.291 , pp. 997-1013
    • Jager, S.1    Groll, M.2    Huber, R.3    Wolf, D.H.4    Heinemeyer, W.5
  • 26
    • 33646841837 scopus 로고    scopus 로고
    • Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate
    • Kisselev A.F., Callard A., and Goldberg A.L. Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. J Biol Chem 281 (2006) 8582-8590
    • (2006) J Biol Chem , vol.281 , pp. 8582-8590
    • Kisselev, A.F.1    Callard, A.2    Goldberg, A.L.3
  • 27
    • 33845532759 scopus 로고    scopus 로고
    • Activity patterns of proteasome subunits reflect bortezomib sensitivity of hematologic malignancies and are variable in primary human leukemia cells
    • Kraus M., Ruckrich T., Reich M., et al. Activity patterns of proteasome subunits reflect bortezomib sensitivity of hematologic malignancies and are variable in primary human leukemia cells. Leukemia 21 (2007) 84-92
    • (2007) Leukemia , vol.21 , pp. 84-92
    • Kraus, M.1    Ruckrich, T.2    Reich, M.3
  • 28
    • 38749115417 scopus 로고    scopus 로고
    • Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits
    • Busse A., Kraus M., Na I.K., et al. Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits. Cancer 112 (2008) 659-670
    • (2008) Cancer , vol.112 , pp. 659-670
    • Busse, A.1    Kraus, M.2    Na, I.K.3
  • 29
    • 0032490833 scopus 로고    scopus 로고
    • P210 bcr-abl expression in a primitive haematopoietic cell line models the development of chronic myeloid leukaemia
    • Pierce A., Owen-Lynch P., Spooncer E., Dexter T.M., and Whetton A.D. P210 bcr-abl expression in a primitive haematopoietic cell line models the development of chronic myeloid leukaemia. Oncogene 17 (1998) 667-672
    • (1998) Oncogene , vol.17 , pp. 667-672
    • Pierce, A.1    Owen-Lynch, P.2    Spooncer, E.3    Dexter, T.M.4    Whetton, A.D.5
  • 30
    • 0034254368 scopus 로고    scopus 로고
    • Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance
    • Mahon F.X., Deininger M.W., Schultheis B., et al. Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance. Blood 96 (2000) 1070-1079
    • (2000) Blood , vol.96 , pp. 1070-1079
    • Mahon, F.X.1    Deininger, M.W.2    Schultheis, B.3
  • 31
    • 0032539571 scopus 로고    scopus 로고
    • Inhibitors of the chymotrypsin-like activity of the proteasome based on di- and tri-peptidyl α-keto aldehydes (glyoxals)
    • Lynas J., Harriott P., Healy A., McKervey A., and Walker B. Inhibitors of the chymotrypsin-like activity of the proteasome based on di- and tri-peptidyl α-keto aldehydes (glyoxals). Bioorg Med Chem Lett 8 (1998) 373-378
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 373-378
    • Lynas, J.1    Harriott, P.2    Healy, A.3    McKervey, A.4    Walker, B.5
  • 33
    • 18244406798 scopus 로고    scopus 로고
    • Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib
    • Berkers C.R., Verdoes M., Lichtman E., et al. Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib. Nat Methods 2 (2005) 357-362
    • (2005) Nat Methods , vol.2 , pp. 357-362
    • Berkers, C.R.1    Verdoes, M.2    Lichtman, E.3
  • 34
    • 0037441756 scopus 로고    scopus 로고
    • Specific inhibition of bcr-abl gene expression by small interfering RNA
    • Scherr M., Battmer K., Winkler T., Heidenreich O., Ganser A., and Eder M. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood 101 (2003) 1566-1569
    • (2003) Blood , vol.101 , pp. 1566-1569
    • Scherr, M.1    Battmer, K.2    Winkler, T.3    Heidenreich, O.4    Ganser, A.5    Eder, M.6
  • 35
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of real-time quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia-a Europe against cancer program
    • Gabert J., Beillard E., van der Velden V.H., et al. Standardization and quality control studies of real-time quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia-a Europe against cancer program. Leukemia 17 (2003) 2318-2357
    • (2003) Leukemia , vol.17 , pp. 2318-2357
    • Gabert, J.1    Beillard, E.2    van der Velden, V.H.3
  • 36
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou T., and Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22 (1984) 27-55
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.1    Talalay, P.2
  • 37
    • 0025115736 scopus 로고
    • Abnormally high expression of proteasomes in leukaemic cells
    • Kumatori A., Tanaka K., Inamura N., et al. Abnormally high expression of proteasomes in leukaemic cells. Proc Natl Acad Sci U S A 87 (1990) 7071-7075
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 7071-7075
    • Kumatori, A.1    Tanaka, K.2    Inamura, N.3
  • 38
    • 20244376911 scopus 로고    scopus 로고
    • BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells
    • Andreu E.J., Lledo E., Poch E., et al. BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells. Cancer Res 65 (2005) 3264-3272
    • (2005) Cancer Res , vol.65 , pp. 3264-3272
    • Andreu, E.J.1    Lledo, E.2    Poch, E.3
  • 39
    • 0033920566 scopus 로고    scopus 로고
    • Protease inhibitor induced apoptosis: Accumulation of wt p53, p21 WAF1/CIP1 and induction of apoptosis are independent markers of proteasome inhibition
    • An W.G., Hwang S.G., Trepel J.B., and Blagosklonny M.V. Protease inhibitor induced apoptosis: Accumulation of wt p53, p21 WAF1/CIP1 and induction of apoptosis are independent markers of proteasome inhibition. Leukemia 14 (2000) 1276-1283
    • (2000) Leukemia , vol.14 , pp. 1276-1283
    • An, W.G.1    Hwang, S.G.2    Trepel, J.B.3    Blagosklonny, M.V.4
  • 40
    • 34250845034 scopus 로고    scopus 로고
    • Therapeutic targets in chronic myeloid leukaemia
    • Heaney N.B., and Holyoake T.L. Therapeutic targets in chronic myeloid leukaemia. Hematol Oncol 25 (2007) 66-75
    • (2007) Hematol Oncol , vol.25 , pp. 66-75
    • Heaney, N.B.1    Holyoake, T.L.2
  • 41
    • 0032523919 scopus 로고    scopus 로고
    • Oncogenic abl and src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a ras-independent pathway
    • Dai Z., Quakenbush R.C., Courtney K.D., et al. Oncogenic abl and src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a ras-independent pathway. Genes Dev 12 (1998) 1415-1424
    • (1998) Genes Dev , vol.12 , pp. 1415-1424
    • Dai, Z.1    Quakenbush, R.C.2    Courtney, K.D.3
  • 42
    • 0035108553 scopus 로고    scopus 로고
    • CIS1, a cytokine-inducible SH2 protein, suppresses BCR/ABL-mediated transformation
    • Tauchi T., Yoshimura A., and Ohyashiki K. CIS1, a cytokine-inducible SH2 protein, suppresses BCR/ABL-mediated transformation. Exp Hematol 29 (2001) 356-361
    • (2001) Exp Hematol , vol.29 , pp. 356-361
    • Tauchi, T.1    Yoshimura, A.2    Ohyashiki, K.3
  • 43
    • 4344623889 scopus 로고    scopus 로고
    • Imatinib as a paradigm of targeted therapies
    • Druker B.J. Imatinib as a paradigm of targeted therapies. Adv Cancer Res 91 (2004) 1-30
    • (2004) Adv Cancer Res , vol.91 , pp. 1-30
    • Druker, B.J.1
  • 44
    • 0038066488 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors promote STI571-mediated apoptosis in STI571-sensitive and-resistant Bcr/Abl+ human myeloid leukemia cells
    • Yu C., Rahmani M., Almenara J., Subler M., et al. Histone deacetylase inhibitors promote STI571-mediated apoptosis in STI571-sensitive and-resistant Bcr/Abl+ human myeloid leukemia cells. Cancer Res 63 (2003) 2118-2126
    • (2003) Cancer Res , vol.63 , pp. 2118-2126
    • Yu, C.1    Rahmani, M.2    Almenara, J.3    Subler, M.4
  • 45
    • 0035313251 scopus 로고    scopus 로고
    • In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents
    • Kano Y., Akutsu M., Tsunoda S., et al. In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents. Blood 97 (2001) 1999-2007
    • (2001) Blood , vol.97 , pp. 1999-2007
    • Kano, Y.1    Akutsu, M.2    Tsunoda, S.3
  • 46
    • 0037079720 scopus 로고    scopus 로고
    • Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro
    • Mow B.M., Chandra J., Svingen P., et al. Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro. Blood 99 (2002) 664-671
    • (2002) Blood , vol.99 , pp. 664-671
    • Mow, B.M.1    Chandra, J.2    Svingen, P.3
  • 47
    • 0036682301 scopus 로고    scopus 로고
    • Crystal structures of the kinase domain of c-abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)
    • Nagar B., Bornmann W.G., Pellicena P., et al. Crystal structures of the kinase domain of c-abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Res 62 (2002) 4236-4243
    • (2002) Cancer Res , vol.62 , pp. 4236-4243
    • Nagar, B.1    Bornmann, W.G.2    Pellicena, P.3
  • 49
    • 0141761420 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in Bcr-Abl-positive cell lines sensitive and resistant to imatinib mesylate
    • Gatto S., Scappini B., Pham L., et al. The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in Bcr-Abl-positive cell lines sensitive and resistant to imatinib mesylate. Haematologica 88 (2003) 853-863
    • (2003) Haematologica , vol.88 , pp. 853-863
    • Gatto, S.1    Scappini, B.2    Pham, L.3
  • 50
    • 33745728140 scopus 로고    scopus 로고
    • Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341 and MG-132
    • Crawford L.J., Walker B., Ovaa H., et al. Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341 and MG-132. Cancer Res 66 (2006) 6379-6386
    • (2006) Cancer Res , vol.66 , pp. 6379-6386
    • Crawford, L.J.1    Walker, B.2    Ovaa, H.3
  • 51
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia-advances in biology and new approaches to treatment
    • Goldman J.M., and Melo J.V. Chronic myeloid leukemia-advances in biology and new approaches to treatment. N Engl J Med 349 (2003) 1451-1464
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 52
    • 33750209537 scopus 로고    scopus 로고
    • A novel proteasome inhibitor NPI-0052 as an anticancer therapy
    • Chauhan D., Hideshima T., and Anderson K.C. A novel proteasome inhibitor NPI-0052 as an anticancer therapy. Br J Cancer 95 (2006) 961-965
    • (2006) Br J Cancer , vol.95 , pp. 961-965
    • Chauhan, D.1    Hideshima, T.2    Anderson, K.C.3
  • 53
    • 36148944490 scopus 로고    scopus 로고
    • Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma
    • Kuhn D.J., Chen Q., Voorhees P.M., et al. Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood 110 (2007) 3281-3290
    • (2007) Blood , vol.110 , pp. 3281-3290
    • Kuhn, D.J.1    Chen, Q.2    Voorhees, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.