A novel role for Gemin5 in mRNA translation

Nucleic Acids Research

Volumn 37, Issue 2, 2009, Pages 582-590

  Pacheco, Almudena ^a   De Quinto, Sonia López ^a   Ramajo, Jorge ^a   Fernández, Noemí ^a   Martínez Salas, Encarnación ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GEMININ; INITIATION FACTOR 4E; MESSENGER RNA; POLYPEPTIDE; PROTEIN P170A; PROTEIN P170B; RIBONUCLEOPROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; BIOGENESIS; CONTROLLED STUDY; DOWN REGULATION; FOOT AND MOUTH DISEASE VIRUS; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEOMICS; REGULATORY MECHANISM; RNA TRANSLATION; TRANSLATION INITIATION;

CELL LINE; DOWN-REGULATION; HUMANS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PEPTIDES; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA, MESSENGER; RNA, VIRAL; RNA-BINDING PROTEINS; SMN COMPLEX PROTEINS;

EUKARYOTA; FOOT-AND-MOUTH DISEASE VIRUS; HEPATITIS C VIRUS;

EID: 59649126267     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn979     Document Type: Article

References (52)

1. Sonenberg,N. and Dever,T.E. (2003) Eukaryotic translation initiation factors and regulators. Curr. Opin. Struct. Biol., 13, 56-63.
2. Pestova,T.V., Lorsch,J.R. and Hellen,C.U.T. (2007) The mechanism of translation initiation in eukaryotes. In Mathews,M.B., Sonenberg,N. and Hershey,J.W.B. (eds), Translation Control in Biology and Medicine. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp. 87-128.
3. Pelletier,J. and Sonenberg,N. (1988) Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature, 334, 320-325.
4. Jang,S.K., Krausslich,H.G., Nicklin,M.J., Duke,G.M., Palmenberg,A.C. and Wimmer,E. (1988) A segment of the 50 non-translated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol., 62, 2636-2643.
5. Martinez-Salas,E. (2008) The impact of RNA structure on picornavirus IRES activity. Trends Microbiol., 16, 230-237.
6. Baird,S.D., Turcotte,M., Korneluk,R.G. and Holcik,M. (2006) Searching for IRES. RNA, 12, 1755-1785.
7. Spriggs,K.A., Bushell,M., Mitchell,S.A. and Willis,A.E. (2005) Internal ribosome entry segment-mediated translation during apoptosis: The role of IRES-trans-acting factors. Cell Death Differ., 12, 585-591.
8. Pestova,T.V., Kolupaeva,V.G., Lomakin,I.B., Pilipenko,E.V., Shatsky,I.N., Agol,V.I. and Hellen,C.U. (2001) Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl Acad. Sci. USA, 98, 7029-7036.
9. Pestova,T.V., Shatsky,I.N., Fletcher,S.P., Jackson,R.J. and Hellen,C.U. (1998) A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs. Genes Dev., 12, 67-83.
10. Fraser,C.S. and Doudna,J.A. (2007) Structural and mechanistic insights into hepatitis C viral translation initiation. Nat. Rev. Microbiol. 5, 29-38.
11. Martinez-Salas,E., Pacheco,A., Serrano,P. and Fernandez,N. (2008) New insights into internal ribosome entry site elements relevant for viral gene expression. J. Gen. Virol., 89, 611-626.
12. Semler,B.L. and Waterman,M.L. (2008) IRES-mediated pathways to polysomes: Nuclear versus cytoplasmic routes. Trends Microbiol., 16, 1-5.
13. Anderson,P. and Kedersha,N. (2008) Stress granules: The Tao of RNA triage. Trends Biochem. Sci., 33, 141-150.
14. Lopez de Quinto,S., Lafuente,E. and Martinez-Salas,E. (2001) IRES interaction with translation initiation factors: Functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GII. RNA, 7, 1213-1226.
15. Lopez de Quinto,S., Saiz,M., de la Morena,D., Sobrino,F. and Martinez-Salas,E. (2002) IRES-driven translation is stimulated separately by the FMDV 3′-NCR and poly(A) sequences. Nucleic Acids Res., 30, 4398-4405.
16. Battle,D.J., Lau,C.K., Wan,L., Deng,H., Lotti,F. and Dreyfuss,G. (2006) The Gemin5 protein of the SMN complex identifies snRNAs. Mol. Cell 23, 273-279.
17. Wollerton,M.C., Gooding,C., Wagner,E.J., Garcia-Blanco,M.A. and Smith,C.W. (2004) Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol. Cell 13, 91-100.
18. Burgui,I., Yanguez,E., Sonenberg,N. and Nieto,A. (2007) Influenza virus mRNA translation revisited: Is the eIF4E cap-binding factor required for viral mRNA translation? J. Virol., 81, 12427-12438.
19. Fernandez-Miragall,O. and Martinez-Salas,E. (2003) Structural organization of a viral IRES depends on the integrity of the GNRA motif. RNA, 9, 1333-1344.
20. Fernandez-Miragall,O., Ramos,R., Ramajo,J. and Martinez-Salas,E. (2006) Evidence of reciprocal tertiary interactions between conserved motifs involved in organizing RNA structure essential for internal initiation of translation. RNA, 12, 223-234.
21. Lopez de Quinto,S. and Martinez-Salas,E. (1999) Involvement of the aphthovirus RNA region located between the two functional AUGs in start codon selection. Virology, 255, 324-336.
22. Lafuente,E., Ramos,R. and Martinez-Salas,E. (2002) Long-range RNA-RNA interactions between distant regions of the hepatitis C virus internal ribosome entry site element. J. Gen. Virol., 83, 1113-1121.
23. Pacheco,A., Reigadas,S. and Martinez-Salas,E. (2008) Riboproteomic analysis of polypeptides interacting with the internal ribosome entry site element of foot-and-mouth disease virus. Proteomics, 8, 4782-4790.
24. Shevchenko,A., Wilm,M., Vorm,O. and Mann,M. (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem., 68, 850-858.
25. Lopez de Quinto,S. and Martinez-Salas,E. (2000) Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo. RNA, 6, 1380-1392.
26. Rodriguez Pulido,M., Serrano,P., Saiz,M. and Martinez-Salas,E. (2007) Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins. Virology, 364, 466-474.
27. Gubitz,A.K., Mourelatos,Z., Abel,L., Rappsilber,J., Mann,M. and Dreyfuss,G. (2002) Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. J. Biol. Chem., 277, 5631-5636.
28. Godbout,R., Packer,M. and Bie,W. (1998) Overexpression of a DEAD box protein (DDX1) in neuroblastoma and retinoblastoma cell lines. J. Biol. Chem., 273, 21161-21168.
29. Squatrito,M., Mancino,M., Donzelli,M., Areces,L.B. and Draetta,G.F. (2004) EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes. Oncogene, 23, 4454-4465.
30. Lopez de Quinto,S. and Martinez-Salas,E. (1997) Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation. J. Virol., 71, 4171-4175.
31. Fernandez-Miragall,O. and Martinez-Salas,E. (2007) In vivo footprint of a picornavirus internal ribosome entry site reveals differences in accessibility to specific RNA structural elements. J. Gen. Virol., 88, 3053-3062.
32. Vagnozzi,A., Stein,D.A., Iversen,P.L. and Rieder,E. (2007) Inhibition of foot-and-mouth disease virus infections in cell cultures with antisense morpholino oligomers. J Virol., 81, 11669-11680.
33. Will,C.L. and Luhrmann,R. (2001) Spliceosomal UsnRNP biogenesis, structure and function. Curr. Opin. Cell Biol., 13, 290-301.
34. Borman,A.M., Le Mercier,P., Girard,M. and Kean,K.M. (1997) Comparison of picornaviral IRES-driven internal initiation of translation in cultured cells of different origins. Nucleic Acids Res., 25, 925-932.
35. Saiz,J.C., Lopez de Quinto,S., Ibarrola,N., Lopez-Labrador,F.X., Sanchez-Tapias,J.M., Rodes,J. and Martinez-Salas,E. (1999) Internal initiation of translation efficiency in different hepatitis C genotypes isolated from interferon treated patients. Arch. Virol., 144 215-229.
36. Monie,T.P., Perrin,A.J., Birtley,J.R., Sweeney,T.R., Karakasiliotis,I., Chaudhry,Y., Roberts,L.O., Matthews,S., Goodfellow,I.G. and Curry,S. (2007) Structural insights into the transcriptional and translational roles of Ebp1. EMBO J., 26, 3936-3944.
37. Andreev,D.E., Fernandez-Miragall,O., Ramajo,J., Dmitriev,S.E., Terenin,I.M., Martinez-Salas,E. and Shatsky,I.N. (2007) Differential factor requirement to assemble translation initiation complexes at the alternative start codons of foot-and-mouth disease virus RNA. RNA, 13, 1366-1374.
38. Florez,P.M., Sessions,O.M., Wagner,E.J., Gromeier,M. and Garcia-Blanco,M.A. (2005) The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation. J. Virol., 79, 6172-6179.
39. Fierro-Monti,I., Mohammed,S., Matthiesen,R., Santoro,R., Burns,J.S., Williams,D.J., Proud,C.G., Kassem,M., Jensen,O.N. and Roepstor.,P. (2006) Quantitative proteomics identifies Gemin5, a scaffolding protein involved in ribonucleoprotein assembly, as a novel partner for eukaryotic initiation factor 4E. J. Proteome Res., 5, 1367-1378.
40. Yong,J., Wan,L. and Dreyfuss,G. (2004) Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol., 14, 226-232.
41. Fuller-Pace,F.V. (2006) DExD/H box RNA helicases: Multifunctional proteins with important roles in transcriptional regulation. Nucleic Acids Res., 34, 4206-4215.
42. Buratti,E., Tisminetzky,S., Zotti,M. and Baralle,F.E. (1998) Functional analysis of the interaction between HCV 5'UTR and putative subunits of eukaryotic translation initiation factor eIF3. Nucleic Acids Res., 26, 3179-3187.
43. Kaminski,A., Hunt,S.L., Patton,J.G. and Jackson,R.J. (1995) Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA. RNA, 1, 924-938.
44. Conte,M.R., Grune,T., Ghuman,J., Kelly,G., Ladas,A., Matthews,S. and Curry,S. (2000) Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold. EMBO J., 19, 3132-3141.
45. Almstead,L.L. and Sarnow,P. (2007) Inhibition of U snRNP assembly by a virus-encoded proteinase. Genes Dev., 21, 1086-1097.
46. Richter,J.D. (2007) CPEB: A life in translation. Trends Biochem. Sci. 32, 279-285.
47. Merrill,M.K. and Gromeier,M. (2006) The double-stranded RNA binding protein 76:NF45 heterodimer inhibits translation initiation at the rhinovirus type 2 internal ribosome entry site. J. Virol., 80 6936-6942.
48. Hao le,T., Fuller,H.R., Lam le,T., Le,T.T., Burghes,A.H. and Morris,G.E. (2007) Absence of gemin5 from SMN complexes in nuclear Cajal bodies. BMC Cell Biol., 8, 28.
49. Bedard,K.M., Daijogo,S. and Semler,B.L. (2007) A nucleocytoplasmic SR protein functions in viral IRES-mediated translation initiation. EMBO J., 26, 459-467.
50. Michlewski,G., Sanford,J.R. and Caceres,J.F. (2008) The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1. Mol. Cell, 30, 179-189.
51. Cammas,A., Pileur,F., Bonnal,S., Lewis,S.M., Leveque,N., Holcik,M. and Vagner,S. (2007) Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs. Mol. Biol. Cell, 18, 5048-5059.
52. Kim,T.D., Woo,K.C., Cho,S., Ha,D.C., Jang,S.K. and Kim,K.T. (2007) Rhythmic control of AANAT translation by hnRNP Q in circadian melatonin production. Genes Dev., 21, 797-810.