Synthesis and structure-function analysis of Fe(II)-form-selective antibacterial inhibitors of Escherichia coli methionine aminopeptidase

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 4, 2009, Pages 1080-1083

  Wang, Wen Long ^a   Chai, Sergio C ^a   Ye, Qi Zhuang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antibacterial; Catechol; Drug discovery; Metalloform; Methionine aminopeptidase; Protease

Indexed keywords

ANTIINFECTIVE AGENT; CATECHOL DERIVATIVE; FURAN DERIVATIVE; HETEROCYCLIC COMPOUND; IRON; METHIONYL AMINOPEPTIDASE; THIAZOLE; THIOPHENE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; IC 50; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINOPEPTIDASES; ANTI-BACTERIAL AGENTS; CATECHOLS; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DISCOVERY; ESCHERICHIA COLI; FERROUS COMPOUNDS; FURANS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 59649123584     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.01.011     Document Type: Article

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