-
2
-
-
0032552112
-
The stomach is a source of leptin
-
Bado A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, Moizo L, Lehy T, Guerre-Millo M, Le Marchand-Brustel Y, et al. (1998) The stomach is a source of leptin. Nature 394:790-793.
-
(1998)
Nature
, vol.394
, pp. 790-793
-
-
Bado, A.1
Levasseur, S.2
Attoub, S.3
Kermorgant, S.4
Laigneau, J.P.5
Bortoluzzi, M.N.6
Moizo, L.7
Lehy, T.8
Guerre-Millo, M.9
Le Marchand-Brustel, Y.10
-
3
-
-
59649091876
-
-
Beal SL, Boeckmann AJ, Sheiner LB, and NONMEM Project Group (2007) NONMEM Users Guides, University of California, San Francisco, CA.
-
Beal SL, Boeckmann AJ, Sheiner LB, and NONMEM Project Group (2007) NONMEM Users Guides, University of California, San Francisco, CA.
-
-
-
-
4
-
-
15744399214
-
Altered body composition and metabolism in the male offspring of high fat-fed rats
-
Buckley AJ, KeserüB, Briody J, Thompson M, Ozanne SE, and Thompson CH (2005) Altered body composition and metabolism in the male offspring of high fat-fed rats. Metabolism 54:500-507.
-
(2005)
Metabolism
, vol.54
, pp. 500-507
-
-
Buckley, A.J.1
Keserü, B.2
Briody, J.3
Thompson, M.4
Ozanne, S.E.5
Thompson, C.H.6
-
5
-
-
0034046561
-
Secretory granules of endocrine and chief cells of human stomach mucosa contain leptin
-
Cinti S, Matteis RD, Picó C, Ceresi E, Obrador A, Maffeis C, Oliver J, and Palou A (2000) Secretory granules of endocrine and chief cells of human stomach mucosa contain leptin. Int J Obes Relat Metab Disord 24:789-793.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 789-793
-
-
Cinti, S.1
Matteis, R.D.2
Picó, C.3
Ceresi, E.4
Obrador, A.5
Maffeis, C.6
Oliver, J.7
Palou, A.8
-
6
-
-
0027769745
-
Comparison of four basic models of indirect pharmacodynamic responses
-
Dayneka NL, Garg V, and Jusko WJ (1993) Comparison of four basic models of indirect pharmacodynamic responses. J Pharmacokinet Biopharm 21:457-478.
-
(1993)
J Pharmacokinet Biopharm
, vol.21
, pp. 457-478
-
-
Dayneka, N.L.1
Garg, V.2
Jusko, W.J.3
-
7
-
-
33644967119
-
The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity
-
Dyck DJ, Heigenhauser GJ, and Bruce CR (2006) The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity. Acta Physiol (Oxf) 186:5-16.
-
(2006)
Acta Physiol (Oxf)
, vol.186
, pp. 5-16
-
-
Dyck, D.J.1
Heigenhauser, G.J.2
Bruce, C.R.3
-
8
-
-
0033931981
-
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
-
El-Haschimi K, Pierroz DD, Hileman SM, Bjørbaek C, and Flier JS (2000) Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 105:1827-1832.
-
(2000)
J Clin Invest
, vol.105
, pp. 1827-1832
-
-
El-Haschimi, K.1
Pierroz, D.D.2
Hileman, S.M.3
Bjørbaek, C.4
Flier, J.S.5
-
9
-
-
34547482420
-
Effect of age and moderate food restriction on insulin sensitivity in Wistar rats: Role of adiposity
-
Escrivá F, Gavete ML, Fermín Y, Pérez C, Gallardo N, Alvarez C, Andrés A, Ros M, and Carrascosa JM (2007) Effect of age and moderate food restriction on insulin sensitivity in Wistar rats: role of adiposity. J Endocrinol 194:131-141.
-
(2007)
J Endocrinol
, vol.194
, pp. 131-141
-
-
Escrivá, F.1
Gavete, M.L.2
Fermín, Y.3
Pérez, C.4
Gallardo, N.5
Alvarez, C.6
Andrés, A.7
Ros, M.8
Carrascosa, J.M.9
-
10
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman JM and Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395:763-770.
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
11
-
-
0942279569
-
Energy homeostasis, obesity and eating disorders: Recent advances in endocrinology
-
Gale SM, Castracane VD, and Mantzoros CS (2004) Energy homeostasis, obesity and eating disorders: recent advances in endocrinology. J Nutr 134:295-298.
-
(2004)
J Nutr
, vol.134
, pp. 295-298
-
-
Gale, S.M.1
Castracane, V.D.2
Mantzoros, C.S.3
-
12
-
-
0024197770
-
Development of diabetes in the non-obese NIDDM rat (GK rat)
-
Goto Y, Suzuki K, Ono T, Sasaki M, and Toyota T (1988) Development of diabetes in the non-obese NIDDM rat (GK rat). Adv Exp Med Biol 246:29-31.
-
(1988)
Adv Exp Med Biol
, vol.246
, pp. 29-31
-
-
Goto, Y.1
Suzuki, K.2
Ono, T.3
Sasaki, M.4
Toyota, T.5
-
13
-
-
0003633755
-
-
Institute of Laboratory Animal Resources , 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington, DC
-
Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington, DC.
-
(1996)
Guide for the Care and Use of Laboratory Animals
-
-
-
14
-
-
0032789522
-
Energy intake and utilization vary during development in rats
-
Iossa S, Lionetti L, Mollica MP, Barletta A, and Liverini G (1999) Energy intake and utilization vary during development in rats. J Nutr 129:1593-1596.
-
(1999)
J Nutr
, vol.129
, pp. 1593-1596
-
-
Iossa, S.1
Lionetti, L.2
Mollica, M.P.3
Barletta, A.4
Liverini, G.5
-
15
-
-
0029894050
-
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes
-
Kallen CB and Lazar MA (1996) Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A 93:5793-5796.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5793-5796
-
-
Kallen, C.B.1
Lazar, M.A.2
-
16
-
-
37249046860
-
Central leptin insufficiency syndrome: An interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions
-
Kalra SP (2008) Central leptin insufficiency syndrome: an interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions. Peptides 29:127-138.
-
(2008)
Peptides
, vol.29
, pp. 127-138
-
-
Kalra, S.P.1
-
17
-
-
0031589139
-
Leptin is a four-helix bundle: Secondary structure by NMR
-
Kline AD, Becker GW, Churgay LM, Landen BE, Martin DK, Muth WL, Rathnachalam R, Richardson JM, Schoner B, Ulmer M, et al. (1997) Leptin is a four-helix bundle: secondary structure by NMR. FEBS Lett 407:239-242.
-
(1997)
FEBS Lett
, vol.407
, pp. 239-242
-
-
Kline, A.D.1
Becker, G.W.2
Churgay, L.M.3
Landen, B.E.4
Martin, D.K.5
Muth, W.L.6
Rathnachalam, R.7
Richardson, J.M.8
Schoner, B.9
Ulmer, M.10
-
18
-
-
0035516188
-
Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats
-
Larsen PJ, Fledelius C, Knudsen LB, and Tang-Christensen M (2001) Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats. Diabetes 50:2530-2539.
-
(2001)
Diabetes
, vol.50
, pp. 2530-2539
-
-
Larsen, P.J.1
Fledelius, C.2
Knudsen, L.B.3
Tang-Christensen, M.4
-
19
-
-
0035756691
-
Growth curve analyses in selected duck lines
-
Maruyama K, Vinyard B, Akbar MK, Shafer DJ, and Turk CM (2001) Growth curve analyses in selected duck lines. Br Poult Sci 42:574-582.
-
(2001)
Br Poult Sci
, vol.42
, pp. 574-582
-
-
Maruyama, K.1
Vinyard, B.2
Akbar, M.K.3
Shafer, D.J.4
Turk, C.M.5
-
20
-
-
24944567409
-
Simulated high altitude selectively decreases protein intake and lean mass gain in rats
-
Morel OE, Aubert R, Richalet JP, and Chapelot D (2005) Simulated high altitude selectively decreases protein intake and lean mass gain in rats. Physiol Behav 86:145-153.
-
(2005)
Physiol Behav
, vol.86
, pp. 145-153
-
-
Morel, O.E.1
Aubert, R.2
Richalet, J.P.3
Chapelot, D.4
-
21
-
-
38349039301
-
Follow-up of GK rats during prediabetes highlights increased insulin action and fat deposition despite low insulin secretion
-
Movassat J, Bailbé D, Lubrano-Berthelier C, Picarel-Blanchot F, Bertin E, Mourot J, and Portha B (2008) Follow-up of GK rats during prediabetes highlights increased insulin action and fat deposition despite low insulin secretion. Am J Physiol Endocrinol Metab 294:E168-E175.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Movassat, J.1
Bailbé, D.2
Lubrano-Berthelier, C.3
Picarel-Blanchot, F.4
Bertin, E.5
Mourot, J.6
Portha, B.7
-
22
-
-
17844401180
-
Molecular and anatomical determinants of central leptin resistance
-
Münzberg H and Myers MG Jr (2005) Molecular and anatomical determinants of central leptin resistance. Nat Neurosci 8:566-570.
-
(2005)
Nat Neurosci
, vol.8
, pp. 566-570
-
-
Münzberg, H.1
Myers Jr, M.G.2
-
24
-
-
23744516690
-
Disease system analysis: Basic disease progression models in degenerative disease
-
Post TM, Freijer JI, DeJongh J, and Danhof M (2005) Disease system analysis: basic disease progression models in degenerative disease. Pharm Res 22:1038-1049.
-
(2005)
Pharm Res
, vol.22
, pp. 1038-1049
-
-
Post, T.M.1
Freijer, J.I.2
DeJongh, J.3
Danhof, M.4
-
25
-
-
0037743488
-
Long-term feeding effects of heated and fried oils on hepatic antioxidant enzymes, absorption and excretion of fat in rats
-
Purushothama S, Ramachandran HD, Narasimhamurthy K, and Raina PL (2003) Long-term feeding effects of heated and fried oils on hepatic antioxidant enzymes, absorption and excretion of fat in rats. Mol Cell Biochem 247:95-99.
-
(2003)
Mol Cell Biochem
, vol.247
, pp. 95-99
-
-
Purushothama, S.1
Ramachandran, H.D.2
Narasimhamurthy, K.3
Raina, P.L.4
-
26
-
-
33645888693
-
Nutrition and aging: Changes in the regulation of energy metabolism with aging
-
Roberts SB and Rosenberg I (2006) Nutrition and aging: changes in the regulation of energy metabolism with aging. Physiol Rev 86:651-667.
-
(2006)
Physiol Rev
, vol.86
, pp. 651-667
-
-
Roberts, S.B.1
Rosenberg, I.2
-
27
-
-
33750331204
-
The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes
-
Rubino F, Forgione A, Cummings DE, Vix M, Gnuli D, Mingrone G, Castagneto M, and Marescaux J (2006) The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg 244:741-749.
-
(2006)
Ann Surg
, vol.244
, pp. 741-749
-
-
Rubino, F.1
Forgione, A.2
Cummings, D.E.3
Vix, M.4
Gnuli, D.5
Mingrone, G.6
Castagneto, M.7
Marescaux, J.8
-
28
-
-
42449100763
-
Pharmacogenomics of metabolic effects of rosiglitazone
-
Seda O, Sedová L, Oliyarnyk O, Kazdová L, Krenová D, Corbeil G, Hamet P, Tremblay J, and Kren V (2008) Pharmacogenomics of metabolic effects of rosiglitazone. Pharmacogenomics 9:141-155.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 141-155
-
-
Seda, O.1
Sedová, L.2
Oliyarnyk, O.3
Kazdová, L.4
Krenová, D.5
Corbeil, G.6
Hamet, P.7
Tremblay, J.8
Kren, V.9
-
29
-
-
34249279490
-
Animal models in type 2 diabetes research: An overview
-
Srinivasan K and Ramarao P (2007) Animal models in type 2 diabetes research: an overview. Indian J Med Res 125:451-472.
-
(2007)
Indian J Med Res
, vol.125
, pp. 451-472
-
-
Srinivasan, K.1
Ramarao, P.2
-
30
-
-
34047258355
-
Leptin and age-related down-regulation of lipogenic enzymes genes expression in rat white adipose tissue
-
Swierczynski J (2006) Leptin and age-related down-regulation of lipogenic enzymes genes expression in rat white adipose tissue. J Physiol Pharmacol 57 (Suppl 6):85-102.
-
(2006)
J Physiol Pharmacol
, vol.57
, Issue.SUPPL. 6
, pp. 85-102
-
-
Swierczynski, J.1
-
31
-
-
33746886648
-
Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice
-
Ueno N, Inui A, Kalra PS, and Kalra SP (2006) Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides 27:2332-2342.
-
(2006)
Peptides
, vol.27
, pp. 2332-2342
-
-
Ueno, N.1
Inui, A.2
Kalra, P.S.3
Kalra, S.P.4
-
32
-
-
5644225734
-
Maternal dietary vitamin restriction increases body fat content but not insulin resistance in WNIN rat offspring up to 6 months of age
-
Venu L, Harishankar N, Prasanna Krishna T, and Raghunath M (2004) Maternal dietary vitamin restriction increases body fat content but not insulin resistance in WNIN rat offspring up to 6 months of age. Diabetologia 47:1493-1501.
-
(2004)
Diabetologia
, vol.47
, pp. 1493-1501
-
-
Venu, L.1
Harishankar, N.2
Prasanna Krishna, T.3
Raghunath, M.4
-
33
-
-
0032543680
-
A nutrient-sensing pathway regulates leptin gene expression in muscle and fat
-
Wang J, Liu R, Hawkins M, Barzilai N, and Rossetti L (1998) A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393:684-688.
-
(1998)
Nature
, vol.393
, pp. 684-688
-
-
Wang, J.1
Liu, R.2
Hawkins, M.3
Barzilai, N.4
Rossetti, L.5
-
34
-
-
43149112800
-
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome
-
Wang MY, Grayburn P, Chen S, Ravazzola M, Orci L, and Unger RH (2008) Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome. Proc Natl Acad Sci U S A 105:6139-6144.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6139-6144
-
-
Wang, M.Y.1
Grayburn, P.2
Chen, S.3
Ravazzola, M.4
Orci, L.5
Unger, R.H.6
-
35
-
-
84987266075
-
A statistical distribution function of wide applicability
-
Weibull W (1951) A statistical distribution function of wide applicability. J Appl Mech 18:293-297.
-
(1951)
J Appl Mech
, vol.18
, pp. 293-297
-
-
Weibull, W.1
-
36
-
-
0030932272
-
A general model for the origin of allometric scaling laws in biology
-
West GB, Brown JH, and Enquist BJ (1997) A general model for the origin of allometric scaling laws in biology. Science 276:122-126.
-
(1997)
Science
, vol.276
, pp. 122-126
-
-
West, G.B.1
Brown, J.H.2
Enquist, B.J.3
-
37
-
-
0035846161
-
A general model for ontogenetic growth
-
West GB, Brown JH, and Enquist BJ (2001) A general model for ontogenetic growth. Nature 413:628-631.
-
(2001)
Nature
, vol.413
, pp. 628-631
-
-
West, G.B.1
Brown, J.H.2
Enquist, B.J.3
-
38
-
-
0037434713
-
Physiology: Why does metabolic rate scale with body size?
-
discussion 714
-
West GB, Savage VM, Gillooly J, Enquist BJ, Woodruff WH, and Brown JH (2003) Physiology: why does metabolic rate scale with body size? Nature 421:713; discussion 714.
-
(2003)
Nature
, vol.421
, pp. 713
-
-
West, G.B.1
Savage, V.M.2
Gillooly, J.3
Enquist, B.J.4
Woodruff, W.H.5
Brown, J.H.6
-
39
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, and Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
|