메뉴 건너뛰기




Volumn 32, Issue 1, 2009, Pages 111-116

A consensus definition of cataplexy in mouse models of narcolepsy

Author keywords

Atonia; Hypocretin; Orexin; Paralysis; Positive affect; REM sleep

Indexed keywords

CLOMIPRAMINE; FLUOXETINE; OREXIN; OXYBATE SODIUM; PHYSOSTIGMINE; PRAZOSIN; PROTRIPTYLINE; VENLAFAXINE; NEUROPEPTIDE; OREXINS; SIGNAL PEPTIDE;

EID: 59649094276     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.5665/sleep/32.1.111     Document Type: Conference Paper
Times cited : (139)

References (57)
  • 1
    • 0000103314 scopus 로고
    • De la narcolepsie.
    • Gélineau J. De la narcolepsie. Gaz Hop (Paris) 1880;53:626-8.
    • (1880) Gaz Hop (Paris) , vol.53 , pp. 626-628
    • Gélineau, J.1
  • 2
    • 0036467285 scopus 로고    scopus 로고
    • Clinical aspects of narcolepsy-cataplexy across ethnic groups
    • Okun ML, Lin L, Pelin Z, Hong S, Mignot E. Clinical aspects of narcolepsy-cataplexy across ethnic groups. Sleep 2002;25:27-35.
    • (2002) Sleep , vol.25 , pp. 27-35
    • Okun, M.L.1    Lin, L.2    Pelin, Z.3    Hong, S.4    Mignot, E.5
  • 4
    • 0029446732 scopus 로고
    • Clinical aspects and features of cataplexy
    • Guilleminault C, Gelb M. Clinical aspects and features of cataplexy. Adv Neurol 1995;67:65-77.
    • (1995) Adv Neurol , vol.67 , pp. 65-77
    • Guilleminault, C.1    Gelb, M.2
  • 6
    • 0031917206 scopus 로고    scopus 로고
    • Narcolepsy in prepubertal children
    • Guilleminault C, Pelayo R. Narcolepsy in prepubertal children. Ann Neurol 1998;43:135-42.
    • (1998) Ann Neurol , vol.43 , pp. 135-142
    • Guilleminault, C.1    Pelayo, R.2
  • 9
    • 0029437324 scopus 로고
    • Physiology of REM sleep, cataplexy, and sleep paralysis
    • Hishikawa Y, Shimizu T. Physiology of REM sleep, cataplexy, and sleep paralysis. Adv Neurol 1995;67:245-71.
    • (1995) Adv Neurol , vol.67 , pp. 245-271
    • Hishikawa, Y.1    Shimizu, T.2
  • 10
    • 0028358954 scopus 로고
    • Stability of cataplexy over several months - information for the design of therapeutic trials
    • Gelb M, Guilleminault C, Kraemer H, et al. Stability of cataplexy over several months - information for the design of therapeutic trials. Sleep 1994;17:265-73.
    • (1994) Sleep , vol.17 , pp. 265-273
    • Gelb, M.1    Guilleminault, C.2    Kraemer, H.3
  • 11
    • 0036791834 scopus 로고    scopus 로고
    • The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias
    • Mignot E, Lammers G, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002;59:1553-62.
    • (2002) Arch Neurol , vol.59 , pp. 1553-1562
    • Mignot, E.1    Lammers, G.2    Ripley, B.3
  • 12
    • 0033826856 scopus 로고    scopus 로고
    • A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
    • Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000;6:991-7.
    • (2000) Nat Med , vol.6 , pp. 991-997
    • Peyron, C.1    Faraco, J.2    Rogers, W.3
  • 13
    • 0033710848 scopus 로고    scopus 로고
    • Reduced number of hypocretin neurons in human narcolepsy
    • Thannickal TC, Moore RY, Nienhuis R, et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 2000;27:469-74.
    • (2000) Neuron , vol.27 , pp. 469-474
    • Thannickal, T.C.1    Moore, R.Y.2    Nienhuis, R.3
  • 14
    • 24944518715 scopus 로고    scopus 로고
    • Concomitant loss of dynorphin, NARP, and orexin in narcolepsy
    • Crocker A, Espana RA, Papadopoulou M, et al. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology 2005;65:1184-8.
    • (2005) Neurology , vol.65 , pp. 1184-1188
    • Crocker, A.1    Espana, R.A.2    Papadopoulou, M.3
  • 15
    • 0035091595 scopus 로고    scopus 로고
    • Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups
    • Mignot E, Lin L, Rogers W, et al. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet 2001;68:686-99.
    • (2001) Am J Hum Genet , vol.68 , pp. 686-699
    • Mignot, E.1    Lin, L.2    Rogers, W.3
  • 16
    • 0030955520 scopus 로고    scopus 로고
    • Pharmacological aspects of human and canine narcolepsy
    • Nishino S, Mignot E. Pharmacological aspects of human and canine narcolepsy. Prog Neurobiol 1997;52:27-78.
    • (1997) Prog Neurobiol , vol.52 , pp. 27-78
    • Nishino, S.1    Mignot, E.2
  • 17
    • 12144291325 scopus 로고    scopus 로고
    • Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy
    • U.S. Xyrem Multicenter Study Group
    • U.S. Xyrem Multicenter Study Group. Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy. Sleep Med 2004;5:119-23.
    • (2004) Sleep Med , vol.5 , pp. 119-123
  • 19
    • 0026434566 scopus 로고
    • Neuronal activity in narcolepsy: Identification of cataplexy-related cells in the medial medulla
    • Siegel JM, Nienhuis R, Fahringer HM, et al. Neuronal activity in narcolepsy: identification of cataplexy-related cells in the medial medulla. Science 1991;252:1315-8.
    • (1991) Science , vol.252 , pp. 1315-1318
    • Siegel, J.M.1    Nienhuis, R.2    Fahringer, H.M.3
  • 20
    • 3042792719 scopus 로고    scopus 로고
    • Treatment with immunosuppressive and anti-inflammatory agents delays onset of canine genetic narcolepsy and reduces symptom severity
    • Boehmer LN, Wu MF, John J, Siegel JM. Treatment with immunosuppressive and anti-inflammatory agents delays onset of canine genetic narcolepsy and reduces symptom severity. Exp Neurol 2004;188:292-9.
    • (2004) Exp Neurol , vol.188 , pp. 292-299
    • Boehmer, L.N.1    Wu, M.F.2    John, J.3    Siegel, J.M.4
  • 21
    • 0034499322 scopus 로고    scopus 로고
    • Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans
    • Nishino S, Riehl J, Hong J, Kwan M, Reid M, Mignot E. Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans. Neurosci Res 2000;38:437-46.
    • (2000) Neurosci Res , vol.38 , pp. 437-446
    • Nishino, S.1    Riehl, J.2    Hong, J.3    Kwan, M.4    Reid, M.5    Mignot, E.6
  • 23
    • 0036317592 scopus 로고    scopus 로고
    • Analysis of onset location, laterality and propagation of cataplexy in canine narcolepsy
    • Fujiki N, Morris L, Mignot E, Nishino S. Analysis of onset location, laterality and propagation of cataplexy in canine narcolepsy. Psychiatry Clin Neurosci 2002;56:275-6.
    • (2002) Psychiatry Clin Neurosci , vol.56 , pp. 275-276
    • Fujiki, N.1    Morris, L.2    Mignot, E.3    Nishino, S.4
  • 24
    • 0029031471 scopus 로고
    • Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: Implication for the pathophysiology of canine narcolepsy
    • Nishino S, Tafti M, Reid MS, et al. Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy. J Neurosci 1995;15:4806-14.
    • (1995) J Neurosci , vol.15 , pp. 4806-4814
    • Nishino, S.1    Tafti, M.2    Reid, M.S.3
  • 25
    • 0026561190 scopus 로고
    • Activity of medial mesopontine units during cataplexy and sleep- waking states in the narcoleptic dog
    • Siegel JM, Nienhuis R, Fahringer HM, et al. Activity of medial mesopontine units during cataplexy and sleep- waking states in the narcoleptic dog. J Neurosci 1992;12:1640-6.
    • (1992) J Neurosci , vol.12 , pp. 1640-1646
    • Siegel, J.M.1    Nienhuis, R.2    Fahringer, H.M.3
  • 26
    • 0002234129 scopus 로고
    • Behavioral functions of the reticular formation
    • Siegel JM. Behavioral functions of the reticular formation. Brain Res 1979;180:69-105.
    • (1979) Brain Res , vol.180 , pp. 69-105
    • Siegel, J.M.1
  • 27
    • 0020962143 scopus 로고    scopus 로고
    • Siegel JM, Tomaszewski KS. Behavioral organization of reticular formation: studies in the unrestrained cat. I. Cells related to axial, limb, eye, and other movements. J Neurophysiol 1983;50:696-716.
    • Siegel JM, Tomaszewski KS. Behavioral organization of reticular formation: studies in the unrestrained cat. I. Cells related to axial, limb, eye, and other movements. J Neurophysiol 1983;50:696-716.
  • 28
    • 0020608649 scopus 로고
    • Behavioral organization of reticular formation: Studies in the unrestrained cat. II. Cells related to facial movements
    • Siegel JM, Tomaszewski KS, Wheeler RL. Behavioral organization of reticular formation: studies in the unrestrained cat. II. Cells related to facial movements. J Neurophysiol 1983;50:717-23.
    • (1983) J Neurophysiol , vol.50 , pp. 717-723
    • Siegel, J.M.1    Tomaszewski, K.S.2    Wheeler, R.L.3
  • 30
    • 2442544417 scopus 로고    scopus 로고
    • Cataplexy-active neurons in the hypothalamus: Implications for the role of histamine in sleep and waking behavior
    • John J, Wu MF, Boehmer LN, Siegel JM. Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior. Neuron 2004;42:619-34.
    • (2004) Neuron , vol.42 , pp. 619-634
    • John, J.1    Wu, M.F.2    Boehmer, L.N.3    Siegel, J.M.4
  • 31
    • 0032402181 scopus 로고    scopus 로고
    • Neurons containing hypocretin (orexin) project to multiple neuronal systems
    • Peyron C, Tighe DK, van den Pol AN, et al. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 1998;18:9996-10015.
    • (1998) J Neurosci , vol.18 , pp. 9996-10015
    • Peyron, C.1    Tighe, D.K.2    van den Pol, A.N.3
  • 32
    • 0035005977 scopus 로고    scopus 로고
    • Increased and decreased muscle tone with orexin (hypocretin) microinjections in the locus coeruleus and pontine inhibitory area
    • Kiyashchenko LI, Mileykovskiy BY, Lai YY, Siegel JM. Increased and decreased muscle tone with orexin (hypocretin) microinjections in the locus coeruleus and pontine inhibitory area. J Neurophysiol 2001;85:2008-16.
    • (2001) J Neurophysiol , vol.85 , pp. 2008-2016
    • Kiyashchenko, L.I.1    Mileykovskiy, B.Y.2    Lai, Y.Y.3    Siegel, J.M.4
  • 33
    • 0033532499 scopus 로고    scopus 로고
    • Brainstem projections to the ventromedial medulla in cat: Retrograde transport horseradish peroxidase and immunohistochemical studies
    • Lai YY, Clements JR, Wu XY, et al. Brainstem projections to the ventromedial medulla in cat: retrograde transport horseradish peroxidase and immunohistochemical studies. J Comp Neurol 1999;408:419-36.
    • (1999) J Comp Neurol , vol.408 , pp. 419-436
    • Lai, Y.Y.1    Clements, J.R.2    Wu, X.Y.3
  • 34
    • 0034668770 scopus 로고    scopus 로고
    • Activation of pontine and medullary motor inhibitory regions reduces discharge in neurons located in the locus coeruleus and the anatomical equivalent of the midbrain locomotor region
    • Mileykovskiy BY, Kiyashchenko LI, Kodama T, Lai YY, Siegel JM. Activation of pontine and medullary motor inhibitory regions reduces discharge in neurons located in the locus coeruleus and the anatomical equivalent of the midbrain locomotor region. J Neurosci 2000;20:8551-8.
    • (2000) J Neurosci , vol.20 , pp. 8551-8558
    • Mileykovskiy, B.Y.1    Kiyashchenko, L.I.2    Kodama, T.3    Lai, Y.Y.4    Siegel, J.M.5
  • 35
    • 0037129913 scopus 로고    scopus 로고
    • Cataplexy-related neurons in the amygdala of the narcoleptic dog
    • Gulyani S, Wu MF, Nienhuis R, John J, Siegel JM. Cataplexy-related neurons in the amygdala of the narcoleptic dog. Neuroscience 2002;112:355-65.
    • (2002) Neuroscience , vol.112 , pp. 355-365
    • Gulyani, S.1    Wu, M.F.2    Nienhuis, R.3    John, J.4    Siegel, J.M.5
  • 36
    • 0024322452 scopus 로고
    • Exacerbation of human cataplexy by prazosin
    • Aldrich MS, Rogers AE. Exacerbation of human cataplexy by prazosin. Sleep 1989;12:254-6.
    • (1989) Sleep , vol.12 , pp. 254-256
    • Aldrich, M.S.1    Rogers, A.E.2
  • 37
    • 0028314282 scopus 로고
    • Cholinergic mechanisms in canine narcolepsy - I. Modulation of cataplexy via local drug administration into the pontine reticular formation
    • Reid MS, Tafti M, Geary JN, et al. Cholinergic mechanisms in canine narcolepsy - I. Modulation of cataplexy via local drug administration into the pontine reticular formation. Neuroscience 1994;59:511-22.
    • (1994) Neuroscience , vol.59 , pp. 511-522
    • Reid, M.S.1    Tafti, M.2    Geary, J.N.3
  • 38
    • 0023216765 scopus 로고
    • Effect of blood pressure on medial medulla-induced muscle atonia
    • Lai YY, Siegel JM, Wilson WJ. Effect of blood pressure on medial medulla-induced muscle atonia. Am J Physiol 1987;252:H1249-57.
    • (1987) Am J Physiol , vol.252
    • Lai, Y.Y.1    Siegel, J.M.2    Wilson, W.J.3
  • 39
    • 61849094624 scopus 로고
    • Effect of blood pressure changes on atonia produced by stimulation of the medial medulla
    • Siegel J, Wilson W, Tomaszewski K. Effect of blood pressure changes on atonia produced by stimulation of the medial medulla. Sleep Res 1984;13:39.
    • (1984) Sleep Res , vol.13 , pp. 39
    • Siegel, J.1    Wilson, W.2    Tomaszewski, K.3
  • 41
    • 0025255980 scopus 로고
    • Cardiovascular and muscle tone changes produced by microinjection of cholinergic and glutamatergic agonists in dorsolateral pons and medial medulla
    • Lai YY, Siegel JM. Cardiovascular and muscle tone changes produced by microinjection of cholinergic and glutamatergic agonists in dorsolateral pons and medial medulla. Brain Res 1990;514:27-36.
    • (1990) Brain Res , vol.514 , pp. 27-36
    • Lai, Y.Y.1    Siegel, J.M.2
  • 42
    • 0033588184 scopus 로고    scopus 로고
    • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
    • Chemelli RM, Willie JT, Sinton CM, et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999;98:437-51.
    • (1999) Cell , vol.98 , pp. 437-451
    • Chemelli, R.M.1    Willie, J.T.2    Sinton, C.M.3
  • 43
    • 0034992322 scopus 로고    scopus 로고
    • Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
    • Hara J, Beuckmann CT, Nambu T, et al. Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron 2001;30:345-54.
    • (2001) Neuron , vol.30 , pp. 345-354
    • Hara, J.1    Beuckmann, C.T.2    Nambu, T.3
  • 44
    • 0038724250 scopus 로고    scopus 로고
    • Distinct narcolepsy syndromes in orexin receptor-2 and orexin null mice: Molecular genetic dissection of non-REM and REM sleep regulatory processes
    • Willie JT, Chemelli RM, Sinton CM, et al. Distinct narcolepsy syndromes in orexin receptor-2 and orexin null mice: molecular genetic dissection of non-REM and REM sleep regulatory processes. Neuron 2003;38:715-30.
    • (2003) Neuron , vol.38 , pp. 715-730
    • Willie, J.T.1    Chemelli, R.M.2    Sinton, C.M.3
  • 46
    • 84892870509 scopus 로고    scopus 로고
    • Willie J, Yanagisawa M. Lessons from sleepy mice: narcolepsy-cataplexy and the orexin neuropeptide system. In: Bassetti C, Billiard M, Mignot E, eds. Narcolepsy and hypersomnia. New York: Informa Healthcare, 2007:257-78.
    • Willie J, Yanagisawa M. Lessons from sleepy mice: narcolepsy-cataplexy and the orexin neuropeptide system. In: Bassetti C, Billiard M, Mignot E, eds. Narcolepsy and hypersomnia. New York: Informa Healthcare, 2007:257-78.
  • 47
    • 35648943730 scopus 로고    scopus 로고
    • Running promotes wakefulness and increases cataplexy in orexin knockout mice
    • España RA, McCormack SL, Mochizuki T, Scammell TE. Running promotes wakefulness and increases cataplexy in orexin knockout mice. Sleep 2007;30:1417-25.
    • (2007) Sleep , vol.30 , pp. 1417-1425
    • España, R.A.1    McCormack, S.L.2    Mochizuki, T.3    Scammell, T.E.4
  • 48
    • 0001826987 scopus 로고    scopus 로고
    • A behavioral paradigm that elicits narcoleptic attacks in orexin knockout mice
    • Willie J, Chemelli R, Xiong Y, Yanagisawa M. A behavioral paradigm that elicits narcoleptic attacks in orexin knockout mice. Sleep 2000;23:A91-2.
    • (2000) Sleep , vol.23
    • Willie, J.1    Chemelli, R.2    Xiong, Y.3    Yanagisawa, M.4
  • 49
    • 61849105291 scopus 로고    scopus 로고
    • Clark E, Baumann C, Cano G, Scammell T, Mochizuki T. Anticipation of food increases cataplexy in orexin knockout mice. In: Annual Meeting of the Society for Neuroscience; 2007; San Diego, 2007. 632.19.
    • Clark E, Baumann C, Cano G, Scammell T, Mochizuki T. Anticipation of food increases cataplexy in orexin knockout mice. In: Annual Meeting of the Society for Neuroscience; 2007; San Diego, 2007. 632.19.
  • 50
    • 18144370824 scopus 로고    scopus 로고
    • Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions
    • Hara J, Yanagisawa M, Sakurai T. Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions. Neurosci Lett 2005;380:239-42.
    • (2005) Neurosci Lett , vol.380 , pp. 239-242
    • Hara, J.1    Yanagisawa, M.2    Sakurai, T.3
  • 51
    • 35648996655 scopus 로고    scopus 로고
    • Specificity of direct transitions from wake to REM sleep in orexin/ataxin-3 narcoleptic mice
    • Fujiki N, Cheng T, Yoshino F, Nishino S. Specificity of direct transitions from wake to REM sleep in orexin/ataxin-3 narcoleptic mice. Sleep 2006;29:A225.
    • (2006) Sleep , vol.29
    • Fujiki, N.1    Cheng, T.2    Yoshino, F.3    Nishino, S.4
  • 52
    • 61849113162 scopus 로고    scopus 로고
    • Pharmacological evaluation of direct transition from wake to REM sleep (DREM) in orexin/ataxin-3 narcoleptic mice
    • Fujiki N, Cheng T, Yoshino F, Nishino S. Pharmacological evaluation of direct transition from wake to REM sleep (DREM) in orexin/ataxin-3 narcoleptic mice. Sleep 2007;30:A219.
    • (2007) Sleep , vol.30
    • Fujiki, N.1    Cheng, T.2    Yoshino, F.3    Nishino, S.4
  • 53
    • 61849133744 scopus 로고    scopus 로고
    • International classification of sleep disorders. 2nd ed. Chicago, Illinois: American Academy of Sleep Medicine, 2005.
    • International classification of sleep disorders. 2nd ed. Chicago, Illinois: American Academy of Sleep Medicine, 2005.
  • 54
    • 2342602218 scopus 로고    scopus 로고
    • Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat
    • Beuckmann CT, Sinton CM, Williams SC, et al. Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat. J Neurosci 2004;24:4469-77.
    • (2004) J Neurosci , vol.24 , pp. 4469-4477
    • Beuckmann, C.T.1    Sinton, C.M.2    Williams, S.C.3
  • 55
    • 34547670915 scopus 로고    scopus 로고
    • The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats
    • Zhang S, Lin L, Kaur S, et al. The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats. Neuroscience 2007;148:34-43.
    • (2007) Neuroscience , vol.148 , pp. 34-43
    • Zhang, S.1    Lin, L.2    Kaur, S.3
  • 56
    • 0035884938 scopus 로고    scopus 로고
    • Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat
    • Gerashchenko D, Kohls MD, Greco M, et al. Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. J Neurosci 2001;21:7273-83.
    • (2001) J Neurosci , vol.21 , pp. 7273-7283
    • Gerashchenko, D.1    Kohls, M.D.2    Greco, M.3
  • 57
    • 61849132072 scopus 로고    scopus 로고
    • McGregor R, Wu F, Boehmer L, Abordo K, Siegel J. Reduced motivated behavior in hypocretin knockout mice. In: Annual Meeting of the Society for Neuroscience; 2007; San Diego, 2007. 97.7.
    • McGregor R, Wu F, Boehmer L, Abordo K, Siegel J. Reduced motivated behavior in hypocretin knockout mice. In: Annual Meeting of the Society for Neuroscience; 2007; San Diego, 2007. 97.7.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.